Journal Articles

Review

IL‑33 and kidney disease (Review)

Feifei Yang, Ping Zhu, Lihua Duan, Lin Yang, Jiajun Wang

Pages: 3-8 Published online on: 06 November 2015
Review

Activating transcription factor 3 ‑ an endogenous inhibitor of myocardial ischemia-reperfusion injury (Review)

Chao‑Jun Yang, Jun Yang, Zhi‑Xing Fan, Jian Yang

Pages: 9-12 Published online on: 06 November 2015
Article Open Access

Methylene blue exerts a neuroprotective effect against traumatic brain injury by promoting autophagy and inhibiting microglial activation

Mingfei Zhao, Feng Liang, Hangdi Xu, Wei Yan, Jianmin Zhang

Pages: 13-20 Published online on: 11 November 2015
Article Open Access

Melatonin attenuates hypertension-induced renal injury partially through inhibiting oxidative stress in rats

Yu‑Feng Qiao, Wen‑Juan Guo, Lu Li, Shan Shao, Xi Qiao, Jin‑Jin Shao, Qiong Zhang, Rong‑Shan Li, Li‑Hua Wang

Pages: 21-26 Published online on: 02 November 2015
Article Open Access

Long non‑coding RNA‑GAS5 acts as a tumor suppressor in bladder transitional cell carcinoma via regulation of chemokine (C‑C motif) ligand 1 expression

Qifeng Cao, Ning Wang, Juan Qi, Zhengqin Gu, Haibo Shen

Pages: 27-34 Published online on: 05 November 2015
Article Open Access

Silencing of MAP4K4 by short hairpin RNA suppresses proliferation, induces G1 cell cycle arrest and induces apoptosis in gastric cancer cells

Yuan‑Fei Liu, Guo‑Qiang Qu, Yun‑Min Lu, Wu‑Ming Kong, Yuan Liu, Wei‑Xiong Chen, Xiao‑Hong Liao

Pages: 41-48 Published online on: 06 November 2015
Article Open Access

Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro

Yang Hu, Yan Zhang, Kang Tian, Chong Xun, Shouyu Wang, Decheng Lv

Pages: 49-58 Published online on: 11 November 2015
Article Open Access

Microfluidics‑based optimization of neuroleukin‑mediated regulation of articular chondrocyte proliferation

Kang Tian, Weiliang Zhong, Yingqiu Zhang, Baosheng Yin, Weiguo Zhang, Han Liu

Pages: 67-74 Published online on: 10 November 2015
Article Open Access

MicroRNA-21 stimulates epithelial-to-mesenchymal transition and tumorigenesis in clear cell renal cells

Jian Cao, Jun Liu, Ran Xu, Xuan Zhu, Lei Liu, Xiaokun Zhao

Pages: 75-82 Published online on: 13 November 2015
Article Open Access

MicroRNA-148b enhances proliferation and apoptosis in human renal cancer cells via directly targeting MAP3K9

Fang Nie, Tianming Liu, Liang Zhong, Xianggui Yang, Yunhong Liu, Hongwei Xia, Xiaoqiang Liu, Xiaoyan Wang, Zhicheng Liu, Li Zhou, Zhaomin Mao, Qin Zhou, Tingmei Chen

Pages: 83-90 Published online on: 11 November 2015
Article Open Access

A comparative analysis of metal allergens associated with dental alloy prostheses and the expression of HLA-DR in gingival tissue

Xin Zhang, Li‑Cheng Wei, Bin Wu, Li‑Ying Yu, Xiao‑Ping Wang, Yue Liu

Pages: 91-98 Published online on: 12 November 2015
Article Open Access

Abnormal epigenetic regulation of the gene expression levels of Wnt2b and Wnt7b: Implications for neural tube defects

Baoling Bai, Shuyuan Chen, Qin Zhang, Qian Jiang, Huili Li

Pages: 99-106 Published online on: 06 November 2015
Article Open Access

Identification of hub genes of pneumocyte senescence induced by thoracic irradiation using weighted gene co‑expression network analysis

Yonghua Xing, Junling Zhang, Lu Lu, Deguan Li, Yueying Wang, Song Huang, Chengcheng Li, Zhubo Zhang, Jianguo Li, Aimin Meng

Pages: 107-116 Published online on: 13 November 2015
Article Open Access

Effects of maslinic acid on the proliferation and apoptosis of A549 lung cancer cells

Xue Bai, Yi Zhang, Hongfang Jiang, Peng Yang, Hui Li, Yue Zhang, Ping He

Pages: 117-122 Published online on: 11 November 2015
Article Open Access

KiSS‑1‑mediated suppression of the invasive ability of human pancreatic carcinoma cells is not dependent on the level of KiSS‑1 receptor GPR54

Chun‑Hui Wang, Chong Qiao, Ruo‑Chen Wang, Wen‑Ping Zhou

Pages: 123-129 Published online on: 09 November 2015
Article Open Access

Chromosomal radiosensitivity of human immunodeficiency virus positive/negative cervical cancer patients in South Africa

Olivia Herd, Flavia Francies, Jeffrey Kotzen, Trudy Smith, Zwide Nxumalo, Xanthene Muller, Jacobus Slabbert, Anne Vral, Ans Baeyens

Pages: 130-136 Published online on: 05 November 2015
Article Open Access

Hippocampal mitogen-activated protein kinase activation is associated with intermittent hypoxia in a rat model of obstructive sleep apnea syndrome

Ya‑Ning Zhao, Hong‑Yang Wang, Jian‑Min Li, Bao‑Yuan Chen, Guo Xia, Pan‑Pan Zhang, Yan‑Lei Ge

Pages: 137-145 Published online on: 05 November 2015
Article Open Access

Metformin inhibits early stage diethylnitrosamine‑induced hepatocarcinogenesis in rats

Woori Jo, Eun‑Sil Yu, Minsun Chang, Hyun‑Kyu Park, Hyun‑Ji Choi, Jae‑Eun Ryu, Sungwoong Jang, Hyo‑Ju Lee, Ja‑June Jang, Woo‑Chan Son

Pages: 146-152 Published online on: 06 November 2015
Article Open Access

Triptolide reverses the Taxol resistance of lung adenocarcinoma by inhibiting the NF-κB signaling pathway and the expression of NF-κB-regulated drug-resistant genes

Ning Jiang, Xiao‑Peng Dong, Suo‑Lin Zhang, Qing‑Yong You, Xing‑Tao Jiang, Xiao‑Gang Zhao

Pages: 153-159 Published online on: 02 November 2015
Article Open Access

Gene silencing of galectin-3 changes the biological behavior of Eca109 human esophageal cancer cells

Lili Qiao, Ning Liang, Jian Xie, Hui Luo, Jingxin Zhang, Guodong Deng, Yupeng Li, Jiandong Zhang

Pages: 160-166 Published online on: 10 November 2015
Article Open Access

Downregulation of matrix metalloproteinase‑19 induced by respiratory syncytial viral infection affects the interaction between epithelial cells and fibroblasts

Xiuxiu Wu, Huijuan Qi, Yan Yang, Yunhong Yin, Dedong Ma, Hao Li, Yiqing Qu

Pages: 167-173 Published online on: 06 November 2015
Article Open Access

In vitro culture of hFOB1.19 osteoblast cells on TGF-β1-SF-CS three-dimensional scaffolds

Shuang Tong, Lei Xue, Da‑Peng Xu, Zi‑Mei Liu, Yang Du, Xu‑Kai Wang

Pages: 181-187 Published online on: 02 November 2015
Article Open Access

Combination of remote ischemic perconditioning and remote ischemic postconditioning fails to increase protection against myocardial ischemia/reperfusion injury, compared with either alone

Kankai Chen, Meiling Yan, Penglong Wu, Yanwei Qing, Shuai Li, Yongguang Li, Zhifeng Dong, Hongjuan Xia, Dong Huang, Ping Xin, Jingbo Li, Meng Wei

Pages: 197-205 Published online on: 09 November 2015
Article Open Access

NMDA receptors promote neurogenesis in the neonatal rat subventricular zone following hypoxic‑ischemic injury

Qingwei Lai, Peng Hu, Qingyun Li, Xinyu Li, Rui Yuan, Xiaohong Tang, Wei Wang, Xiaoquan Li, Hongbin Fan, Xiaoxing Yin

Pages: 206-212 Published online on: 04 November 2015
Article Open Access

Irradiation alters the differentiation potential of bone marrow mesenchymal stem cells

Yu Wang, Guoying Zhu, Jianping Wang, Junxiang Chen

Pages: 213-223 Published online on: 10 November 2015
Article

Resveratrol attenuates the progress of liver fibrosis via the Akt/nuclear factor-κB pathways

Hui Zhang, Qingfeng Sun, Tingyan Xu, Liang Hong, Rongquan Fu, Jinguo Wu, Jiguang Ding

Pages: 224-230 Published online on: 02 November 2015
Article

Partial deletion of the ROCK2 protein fails to reduce renal fibrosis in a unilateral ureteral obstruction model in mice

Itsuko Baba, Yasuhiro Egi, Kazuo Suzuki

Pages: 231-236 Published online on: 16 November 2015
Article

YAP overexpression promotes the epithelial-mesenchymal transition and chemoresistance in pancreatic cancer cells

Yanli Yuan, Deyu Li, Haibo Li, Liancai Wang, Guangjin Tian, Yadong Dong

Pages: 237-242 Published online on: 11 November 2015
Article

Mitogen-activated protein kinase kinase 3 induces cell cycle arrest via p38 activation mediated Bmi-1 downregulation in hepatocellular carcinoma

Lin Wang, Chen Chen, Shuzhi Feng, Ping Lei, Jianli Tian

Pages: 243-248 Published online on: 13 November 2015
Article

Clinical significance and role of LKB1 in gastric cancer

Shanshan Jiang, Rensheng Chen, Jianan Yu, Nianshuang Li, Rong Ke, Lingyu Luo, Junrong Zou, Jiangnan Zhang, Kunhe Zhang, Nonghua Lu, Deqiang Huang

Pages: 249-256 Published online on: 05 November 2015
Article

Rapid method of luxS and pfs gene inactivation in enterotoxigenic Escherichia coli and the effect on biofilm formation

Xiaoxu Wang, Shiyu Li, Xiaoran Lu, Pan Hu, Haiyan Chen, Zheng Li, Zhaoyang Bu, Xulong Lang, Xinglong Wang

Pages: 257-264 Published online on: 09 November 2015
Article

Adenovirus‑mediated overexpression of cystic fibrosis transmembrane conductance regulator enhances invasiveness and motility of serous ovarian cancer cells

Jiao Xu, Liangbo Lin, Min Yong, Xiaojing Dong, Tinghe Yu, Lina Hu

Pages: 265-272 Published online on: 05 November 2015
Article

MicroRNA-1246 promotes growth and metastasis of colorectal cancer cells involving CCNG2 reduction

Sai Wang, Ya Zeng, Ju‑Mei Zhou, Shao‑Lin Nie, Qiao Peng, Jian Gong, Ji‑Rong Huo

Pages: 273-280 Published online on: 12 November 2015
Article

Inhibition of the expression of aquaporin‑1 by RNA interference in pulmonary epithelial cells and its effects on water transport

Qiuyue Zhang, Jianhua Fu, Xindong Xue

Pages: 281-286 Published online on: 06 November 2015
Article

Resveratrol inhibits mucus overproduction and MUC5AC expression in a murine model of asthma

Zhen‑Hua Ni, Ji‑Hong Tang, Guo Chen, Yi‑Min Lai, Qing‑Ge Chen, Zao Li, Wei Yang, Xu‑Min Luo, Xiong‑Biao Wang

Pages: 287-294 Published online on: 06 November 2015
Article

Microarray expression profiling and gene ontology analysis of long non-coding RNAs in spontaneously hypertensive rats and their potential roles in the pathogenesis of hypertension

Lianglei Hou, Zhenhao Lin, Yunjie Ni, Yihao Wu, Dezhun Chen, Lijuan Song, Xiaoyan Huang, Huanhuan Hu, Deye Yang

Pages: 295-300 Published online on: 11 November 2015
Article

Hepatitis B virus X protein upregulates DNA methyltransferase 3A/3B and enhances SOCS-1CpG island methylation

Xiaoyu Fu, Xiaoling Song, Yanyan Li, Deming Tan, Guozhen Liu

Pages: 301-308 Published online on: 11 November 2015
Article

Propofol protects against the neurotoxicity of 1‑methyl‑4‑phenylpyridinium

Shoushi Wang, Tingting Song, Cuibo Leng, Ketao Lan, Jishun Ning, Haichen Chu

Pages: 309-314 Published online on: 16 November 2015
Article

UHRF1 promotes human osteosarcoma cell invasion by downregulating the expression of E‑cadherin in an Rb1‑dependent manner

Wei Liu, Rui Hong Qiao, Dong Ming Wang, Xiao Wei Huang, Bing Li, Dong Wang

Pages: 315-320 Published online on: 06 November 2015
Article

Overexpression of melanopsin in the retina restores visual function in Royal College of Surgeons rats

Mingming Liu, Jiaman Dai, Wenyi Liu, Chongjian Zhao, Zheng Qin Yin

Pages: 321-326 Published online on: 11 November 2015
Article

Sequential changes in autophagy in diabetic cardiac fibrosis

Huikuan Gao, Qiong Yang, Ruiqing Dong, Fei Hou, Yongquan Wu

Pages: 327-332 Published online on: 06 November 2015
Article

PP242 suppresses bladder cancer cell proliferation and migration through deactivating the mammalian target of rapamycin complex 2/AKT1 signaling pathway

Zhe Zhang, Guojun Zhang, Chuize Kong, Daxin Gong

Pages: 333-338 Published online on: 06 November 2015
Article

Newly synthesized podophyllotoxin derivative, LJ12, induces apoptosis and mitotic catastrophe in non-small cell lung cancer cells in vitro

Ling Hui, Chunyan Sang, Donghong Wang, Xiaohui Wang, Meiliang Wang, Qinghua Jia, Mingren Ma, Shiwu Chen

Pages: 339-346 Published online on: 12 November 2015
Article

Smith‑Magenis syndrome in monozygotic twin fetuses presenting with discordant phenotypes and uteroplacental insufficiency

Yi Zhou, Yingjun Xie, Yunxiao Zhu, Jianzhu Wu, Meijiao Shang, Baojiang Chen, Qun Fang

Pages: 347-352 Published online on: 09 November 2015
Article

FAM172A protein promotes the proliferation of human papillary thyroid carcinoma cells via the p38 mitogen-activated protein kinase pathway

Mei‑Fang Li, Rong Zhang, Ming‑Gao Guo, Lian‑Xi Li, Han‑Kui Lu, Jun‑Xi Lu, Wei‑Ping Jia

Pages: 353-358 Published online on: 11 November 2015
Article

Smac mimetic‑induced caspase‑independent necroptosis requires RIP1 in breast cancer

Gongsheng Jin, Yadong Lan, Fusheng Han, Yiming Sun, Zhe Liu, Mingliang Zhang, Xianfu Liu, Xiaojing Zhang, Jianguo Hu, Hao Liu, Benzhong Wang

Pages: 359-366 Published online on: 10 November 2015
Article

Hydrogen sulfide attenuates doxorubicin-induced cardiotoxicity by inhibiting the expression of peroxiredoxin III in H9c2 cells

Mi‑Hua Liu, Xiao‑Long Lin, Cong Yuan, Jun He, Tian‑Ping Tan, Shao‑Jian Wu, Shan Yu, Li Chen, Jun Liu, Wei Tian, Yu‑Dan Chen, Hong‑Yun Fu, Jian Li, Yuan Zhang

Pages: 367-372 Published online on: 11 November 2015
Article

Catalpol downregulates vascular endothelial‑cadherin expression and induces vascular hyperpermeability

Caiqing Zhang, Qingfa Liu, Fengyun Dong, Liqun Li, Juan Du, Qi Xie, Hesheng Hu, Suhua Yan, Xia Zhou, Changsheng Li, Corrinne G. Lobe, Ju Liu

Pages: 373-378 Published online on: 06 November 2015
Article

MicroRNA‑566 modulates vascular endothelial growth factor by targeting Von Hippel‑Landau in human glioblastoma in vitro and in vivo

Bing Xiao, Xuan Zhou, Minhua Ye, Shigang Lv, Miaojing Wu, Changchun Liao, Lei Han, Chunsheng Kang, Xingen Zhu

Pages: 379-385 Published online on: 09 November 2015
Article

Flap endonuclease 1 silencing is associated with increasing the cisplatin sensitivity of SGC‑7901 gastric cancer cells

Chunhong Xie, Kejia Wang, Daorong Chen

Pages: 386-392 Published online on: 13 November 2015
Article

Imiquimod inhibits the growth of SGC‑7901 cells in vitro through induction of autophagy and apoptosis

Jiong Jiang, Lei Dong, Hai‑Tao Shi, Xiao‑Yan Guo, Bin Qin, Yan Wang, Hong Li

Pages: 393-397 Published online on: 06 November 2015
Article

Endoplasmic reticulum protein 29 is involved in endoplasmic reticulum stress in islet beta cells

Jialin Gao, Yao Zhang, Lizhuo Wang, Libing Xia, Meiqing Lu, Binghua Zhang, Yueping Chen, Lianzhi He

Pages: 398-402 Published online on: 06 November 2015
Article

Trichosanthin reduces the viability of SU‑DHL‑2 cells via the activation of the extrinsic and intrinsic apoptotic pathways

Yingjie Zhu, Yueli Sun, Yuchen Cai, Ou Sha, Wenqi Jiang

Pages: 403-411 Published online on: 06 November 2015
Article

Neuroprotective effects of lycopene pretreatment on transient global cerebral ischemia‑reperfusion in rats: The role of the Nrf2/HO‑1 signaling pathway

Xiaofeng Lei, Lijian Lei, Zhelin Zhang, Yan Cheng

Pages: 412-418 Published online on: 09 November 2015
Article

Protective effects of the Tougu Xiaotong capsule on morphology and osteoprotegerin/nuclear factor-κB ligand expression in rabbits with knee osteoarthritis

Sainan Chen, Yunmei Huang, Wenlie Chen, Guangwen Wu, Naishun Liao, Xihai Li, Meiya Huang, Ruhui Lin, Chao Yu, Xiaodong Li, Xianxiang Liu

Pages: 419-425 Published online on: 11 November 2015
Article

Inhibitory effects of fermented extract of Ophiopogon japonicas on thrombin-induced vascular smooth muscle cells

Jun‑Hui Song, Gi Hee Jeong, Sung Lyea Park, Se Yeon Won, Nam Soo Paek, Bog‑Hieu Lee, Sung‑Kwon Moon

Pages: 426-432 Published online on: 02 November 2015
Article

MicroRNA 28-5p regulates ATP-binding cassette transporter A1 via inhibiting extracellular signal-regulated kinase 2

Jia Liu, Xue‑Qing Liu, Ying Liu, Ya‑Nan Sun, Si Li, Chun‑Mei Li, Jie Li, Wei Tian, Xiao‑Ming Shang, Yun‑Tao Zhou

Pages: 433-440 Published online on: 12 November 2015
Article

Unique dose-dependent effects of the human pregnancy hormone estriol on the ratio of blood IgM to IgG in female mice

Jian Ding, Bao‑Ting Zhu

Pages: 447-452 Published online on: 29 October 2015
Article

Analysis of microRNA and gene networks in human chronic myelogenous leukemia

Kunhao Wang, Zhiwen Xu, Ning Wang, Ye Tian, Xin Sun, Yonggang Ma

Pages: 453-460 Published online on: 05 November 2015
Article

Effect of vascular endothelial growth factor siRNA and wild‑type p53 co‑expressing plasmid in MDA‑MB‑231 cells

Hua Guo, Yang Li, Junlian Gu, Yue Wang, Lianqin Liu, Ping Zhang, Yanan Liu

Pages: 461-468 Published online on: 16 November 2015
Article

Effect of GnT-V knockdown on the proliferation, migration and invasion of the SMMC7721/R human hepatocellular carcinoma drug-resistant cell line

Bo Li, Song Su, Meng‑Yu Zhang, Lei He, Qing‑Da Wang, Kai He

Pages: 469-476 Published online on: 29 October 2015
Article

MicroRNA-148b targets Rho-associated protein kinase 1 to inhibit cell proliferation, migration and invasion in hepatocellular carcinoma

Xian Chen, Lianhua Bo, Wei Lu, Guihua Zhou, Qi Chen

Pages: 477-482 Published online on: 02 November 2015
Article

A regulatory circuit involving miR-143 and DNMT3a mediates vascular smooth muscle cell proliferation induced by homocysteine

Hui‑Ping Zhang, Yan‑Hua Wang, Cheng‑Jian Cao, Xiao‑Ming Yang, Sheng‑Chao Ma, Xue‑Bo Han, Xiao‑Ling Yang, An‑Ning Yang, Jue Tian, Hua Xu, Ming‑Hao Zhang, Yi‑Deng Jiang

Pages: 483-490 Published online on: 12 November 2015
Article

Catalpol preserves neural function and attenuates the pathology of Alzheimer's disease in mice

Jin‑Zhong Huang, Jian Wu, Shoukui Xiang, Shiying Sheng, Ying Jiang, Zhilong Yang, Fei Hua

Pages: 491-496 Published online on: 02 November 2015
Article

SOX18 knockdown suppresses the proliferation and metastasis, and induces the apoptosis of osteosarcoma cells

Zhong Wu, Junjian Liu, Jianguang Wang, Fan Zhang

Pages: 497-504 Published online on: 10 November 2015
Article

MicroRNA‑1915‑3p prevents the apoptosis of lung cancer cells by downregulating DRG2 and PBX2

Chengshan Xu, Hengheng Li, Ling Zhang, Tianjun Jia, Lianning Duan, Chengrong Lu

Pages: 505-512 Published online on: 13 November 2015
Article

Expression of HMGB1 in septic serum induces vascular endothelial hyperpermeability

Yun‑Jiang Zheng, Wei‑Ping Xu, Gang Ding, Yu‑Hua Gao, Hai‑Rong Wang, Shu‑Ming Pan

Pages: 513-521 Published online on: 09 November 2015
Article

NIM811 downregulates transforming growth factor‑β signal transduction in vivo and in vitro

Jing Chen, Dian‑Gang Liu, Hui Wang, Xiao‑Ning Wu, Min Cong, Hong You, Ji‑Dong Jia

Pages: 522-528 Published online on: 16 November 2015
Article

Rac1 mediates HMGB1‑induced hyperpermeability in pulmonary microvascular endothelial cells via MAPK signal transduction

Min Shao, Song‑Tao Tang, Bao Liu, Hua‑Qing Zhu

Pages: 529-535 Published online on: 06 November 2015
Article

Sesamin attenuates mast cell-mediated allergic responses by suppressing the activation of p38 and nuclear factor-κB

Liang Chang Li, Hong Mei Piao, Ming Yu Zheng, Zhen Hua Lin, Guangzhao Li, Guang Hai Yan

Pages: 536-542 Published online on: 11 November 2015
Article
Article

Effects of CDC42 on the proliferation and invasion of gastric cancer cells

Dong‑Shu Du, Xiao‑Zhong Yang, Qiong Wang, Wei‑Jie Dai, Wen‑Xia Kuai, Ye‑Liu Liu, Dechang Chu, Xiao‑Jun Tang

Pages: 550-554 Published online on: 06 November 2015
Article

Mycophenolic acid inhibits the phosphorylation of nuclear factor‑κB and Akt in renal tubular epithelial cells

Fang Zeng, Hui‑Qun Qin, Wei‑Jia Xu, Ming‑Dan Zheng, Hong‑Tao Hu, Hua Shui

Pages: 560-564 Published online on: 06 November 2015
Article

Autoimmune regulator‑overexpressing dendritic cells induce T helper 1 and T helper 17 cells by upregulating cytokine expression

Haijun Li, Dongbei Li, Jitong Sun, Yinan Li, Wei Yang, Yi Li

Pages: 565-571 Published online on: 06 November 2015
Article

MicroRNA-101 induces apoptosis in cisplatin-resistant gastric cancer cells by targeting VEGF-C Retraction in /10.3892/mmr.2021.12333

Guangyan Li, Fang Yang, Shiyu Gu, Zhenjuan Li, Minghui Xue

Pages: 572-578 Published online on: 12 November 2015
Retraction Open Access

[Retracted] Blockade of 11β-hydroxysteroid dehydrogenase type 1 enzyme inhibits experimental collagenase-induced osteoarthritis

Faxin Li, Chuanwu Qiao, Yi Li, Jie Zhu, Jian Chen, Shuya Guo

Pages: 579-579 Published online on: 12 November 2015
Review

Extramedullary hematopoiesis: Elucidating the function of the hematopoietic stem cell niche (Review)

Kouhei Yamamoto, Yukako Miwa, Shiho Abe‑Suzuki, Shinya Abe, Susumu Kirimura, Iichiroh Onishi, Masanobu Kitagawa, Morito Kurata

Pages: 587-591 Published online on: 27 November 2015
Article Open Access

Systematic and comprehensive investigation of the toxicity of curcuminoid‑essential oil complex: A bioavailable turmeric formulation

Madan L. Aggarwal, Karampendethu M. Chacko, Binu T. Kuruvilla

Pages: 592-604 Published online on: 19 November 2015
Article Open Access

Overexpression of TIP30 inhibits the growth and invasion of glioma cells

Yingying Hu, Fengsheng Chen, Feiye Liu, Xinhui Liu, Na Huang, Xiaoli Cai, Yi Sun, Aimin Li, Rongcheng Luo

Pages: 605-612 Published online on: 27 November 2015
Article Open Access

Dose-dependent inhibitory effects of zoledronic acid on osteoblast viability and function in vitro

Xin Huang, Shilong Huang, Fengjin Guo, Fei Xu, Peng Cheng, Yaping Ye, Yonghui Dong, Wei Xiang, Anmin Chen

Pages: 613-622 Published online on: 30 November 2015
Article Open Access

Growth differentiation factor 15 may protect the myocardium from no‑reflow by inhibiting the inflammatory‑like response that predominantly involves neutrophil infiltration

Mei Zhang, Kunying Pan, Qianping Liu, Xin Zhou, Tiemin Jiang, Yuming Li

Pages: 623-632 Published online on: 19 November 2015
Article Open Access

Calycosin‑7‑O‑β‑D‑glucoside attenuates ischemia‑reperfusion injury in vivo via activation of the PI3K/Akt pathway

Min Ren, Xudong Wang, Guoqing Du, Jiawei Tian, Yujie Liu

Pages: 633-640 Published online on: 24 November 2015
Article Open Access

Detection and preliminary screening of the human gene expression profile for Hirschsprung's disease

Xin Wang, Shiqi Wang, Xianqing Jin, Ning Wang, Yuanyuan Luo, Yinping Teng

Pages: 641-650 Published online on: 01 December 2015
Article Open Access

Evaluation of the dynamic pattern of viral evolution in patients with virological breakthrough during treatment with nucleoside/nucleotide analogs by ultra‑deep pyrosequencing

Shaolong Chen, Jing Wu, Erli Gu, Yaojie Shen, Feifei Wang, Wenhong Zhang

Pages: 651-660 Published online on: 19 November 2015
Article Open Access

Valproate attenuates diabetic nephropathy through inhibition of endoplasmic reticulum stress‑induced apoptosis

Xin‑Yi Sun, Han‑Jiao Qin, Ze Zhang, Ye Xu, Xiao‑Chun Yang, Dong‑Ming Zhao, Xiao‑Ning Li, Lian‑Kun Sun

Pages: 661-668 Published online on: 19 November 2015
Article Open Access

Multi‑transgenic minipig models exhibiting potential for hepatic insulin resistance and pancreatic apoptosis

Siyuan Kong, Jinxue Ruan, Leilei Xin, Junhua Fan, Jihan Xia, Zhiguo Liu, Yulian Mu, Shulin Yang, Kui Li

Pages: 669-680 Published online on: 19 November 2015
Article Open Access

Intramuscular injection of bone marrow mononuclear cells contributes to bone repair following midpalatal expansion in rats

Xiaoxia Che, Jie Guo, Xiangdong Li, Lve Wang, Silong Wei

Pages: 681-688 Published online on: 19 November 2015
Article Open Access

Suppression of HSP27 increases the anti‑tumor effects of quercetin in human leukemia U937 cells

Xi Chen, Xiu‑Shuai Dong, Hai‑Yan Gao, Yong‑Fang Jiang, Ying‑Lan Jin, Yu‑Ying Chang, Li‑Yan Chen, Jing‑Hua Wang

Pages: 689-696 Published online on: 23 November 2015
Article Open Access

Effect of P2X4R on airway inflammation and airway remodeling in allergic airway challenge in mice

Hongxia Chen, Qingqing Xia, Xiaoqian Feng, Fangyuan Cao, Hang Yu, Yinli Song, Xiuqin Ni

Pages: 697-704 Published online on: 27 November 2015
Article Open Access

Effects of human vascular endothelial growth factor on reparative dentin formation

Juan Zhang, Xia Liu, Weixian Yu, Yingli Zhang, Ce Shi, Shilei Ni, Qilin Liu, Xiangwei Li, Yingjian Sun, Changyu Zheng, Hongchen Sun

Pages: 705-712 Published online on: 23 November 2015
Article Open Access

Fibroblast growth factor receptor 1 promotes MG63 cell proliferation and is associated with increased expression of cyclin-dependent kinase 1 in osteosarcoma

Wei Zhou, Yue Zhu, Song Chen, Ruijun Xu, Kunzheng Wang

Pages: 713-719 Published online on: 23 November 2015
Article Open Access

Dickkopf Wnt signaling pathway inhibitor 1 regulates the differentiation of mouse embryonic stem cells in vitro and in vivo

Liping Ou, Liaoqiong Fang, Hejing Tang, Hai Qiao, Xiaomei Zhang, Zhibiao Wang

Pages: 720-730 Published online on: 19 November 2015
Article Open Access

Expression of arginase I and inducible nitric oxide synthase in the peripheral blood and lymph nodes of HIV‑positive patients

Naichun Zhang, Jianning Deng, Fengyao Wu, Xiangchan Lu, Lei Huang, Min Zhao

Pages: 731-743 Published online on: 23 November 2015
Article Open Access

Downregulation of caveolin‑1 upregulates the expression of growth factors and regulators in co‑culture of fibroblasts with cancer cells

Xiao‑Yu Shi, Li‑Xia Xiong, Liang Xiao, Chuang Meng, Guan‑Yun Qi, Wen‑Lin Li

Pages: 744-752 Published online on: 24 November 2015
Article Open Access

Peroxiredoxin 6 attenuates ischemia‑ and hypoxia‑induced liver damage of brain‑dead donors

Qiang Tu, Yan Xiong, Lin Fan, Bingbing Qiao, Zhiping Xia, Long Hu, Yanfeng Wang, Guizhu Peng, Qifa Ye

Pages: 753-761 Published online on: 19 November 2015
Article Open Access

Establishment of a dual-color fluorescence tracing orthotopic transplantation model of hepatocellular carcinoma

Qian Chen, Xiaoping Wang, Hao Wu, Hui Wang, Mingao Zhu, Roushu Wang, Ying Wu, Luyao Zhang, Qiao Meng, Ranran Song, Zhixiang Zhuang, Qiang Huang

Pages: 762-768 Published online on: 30 November 2015
Article Open Access

Effect of gallium nitrate on the expression of osteoprotegerin and receptor activator of nuclear factor‑κB ligand in osteoblasts in vivo and in vitro

Jingwu Li, Guang‑Bin Wang, Xue Feng, Jing Zhang, Qin Fu

Pages: 769-777 Published online on: 19 November 2015
Article Open Access

SNAIL transcription factor increases the motility and invasive capacity of prostate cancer cells

Luis A. Osorio, Nancy M. Farfán, Enrique A. Castellón, Héctor R. Contreras

Pages: 778-786 Published online on: 19 November 2015
Article Open Access

Fructus xanthii improves lipid homeostasis in the epididymal adipose tissue of rats fed a high-fat diet

Xiumin Li, Mingxing Yang, Zhipeng Li, Mei Xue, Zhaoshui Shangguan, Zhimin Ou, Ming Liu, Suhuan Liu, Shuyu Yang, Xuejun Li

Pages: 787-795 Published online on: 30 November 2015
Article

Induction of autophagy by the MG‑132 proteasome inhibitor is associated with endoplasmic reticulum stress in MCF‑7 cells

Wenhua Bao, Yiqi Gu, La Ta, Keren Wang, Zheli Xu

Pages: 796-804 Published online on: 23 November 2015
Article

LY294002 prevents lipopolysaccharide‑induced hepatitis in a murine model by suppressing IκB phosphorylation

Zhize Chen, Huimin Liu, Shaoqin Lei, Bo Zhao, Zhongyuan Xia

Pages: 811-816 Published online on: 19 November 2015
Article

Bufalin induces apoptosis in the U‑2OS human osteosarcoma cell line via triggering the mitochondrial pathway

Ya Chen, Meng Li, Zhongji Li, Peng Gao, Xiao Zhou, Jianxin Zhang

Pages: 817-822 Published online on: 19 November 2015
Article

Orally administered betaine reduces photodamage caused by UVB irradiation through the regulation of matrix metalloproteinase-9 activity in hairless mice

A‑Rang Im, Hee Jeong Lee, Ui Joung Youn, Jin Won Hyun, Sungwook Chae

Pages: 823-828 Published online on: 24 November 2015
Article

Epigallocatechin-3-gallate suppresses alveolar epithelial cell apoptosis in seawater aspiration-induced acute lung injury via inhibiting STAT1-caspase-3/p21 associated pathway

Wei Liu, Mingqing Dong, Liyan Bo, Congcong Li, Qingqing Liu, Zhichao Li, Faguang Jin

Pages: 829-836 Published online on: 27 November 2015
Article

4.1N suppresses hypoxia-induced epithelial-mesenchymal transition in epithelial ovarian cancer cells

Letian Zhang, Ajin Hu, Mengrui Li, Hongquan Zhang, Caixia Ren, Xiuli An, Congrong Liu

Pages: 837-844 Published online on: 01 December 2015
Article

Trichostatin A inhibits inflammation in phorbol myristate acetate‑induced macrophages by regulating the acetylation of histone and/or non‑histone proteins

Qian Zhang, Fan Yang, Xun Li, Luwen Wang, Xiaogang Chu, Hong Zhang, Zuojiong Gong

Pages: 845-852 Published online on: 20 November 2015
Article

Correlation between Th17 and nTreg cell frequencies and the stages of progression in chronic hepatitis B

Chun Yang, Fang Cui, Li‑Min Chen, Xue‑Yan Gong, Bo Qin

Pages: 853-859 Published online on: 27 November 2015
Article

Lentivirus‑mediated knockdown of MeCP2 inhibits the growth of colorectal cancer cells in vitro

Ning Song, Keqiang Li, Yan Wang, Zongyou Chen, Liubin Shi

Pages: 860-866 Published online on: 24 November 2015
Article

Effects of miR‑590 on oxLDL‑induced endothelial cell apoptosis: Roles of p53 and NF‑κB

Mei‑Hua Bao, Jian‑Ming Li, Qi‑Liang Zhou, Guang‑Yi Li, Jie Zeng, Juan Zhao, Yi‑Wen Zhang

Pages: 867-873 Published online on: 23 November 2015
Article

Sodium orthovanadate induces the apoptosis of SH-SY5Y cells by inhibiting PIWIL2

Xiaohong Tian, Jun Fan, Weijian Hou, Shuling Bai, Qiang Ao, Hao Tong

Pages: 874-880 Published online on: 26 November 2015
Article

Capsaicin enhances anti-proliferation efficacy of pirarubicin via activating TRPV1 and inhibiting PCNA nuclear translocation in 5637 cells

Long Zheng, Jiaqi Chen, Zhenkun Ma, Wei Liu, Fei Yang, Zhao Yang, Ke Wang, Xinyang Wang, Dalin He, Lei Li, Jin Zeng

Pages: 881-887 Published online on: 30 November 2015
Article

Bioinformatic prediction of the antigenic epitopes of recombinant ferritin of Echinococcus granulosus

Xuelei Liu, Hui Zhao, Wenyan Cao, Yumei Liu, Chuntao Zhang, Xi Lan, Shanshan Peng, Hao Wen, Jianbing Ding, Xiumin Ma

Pages: 888-894 Published online on: 19 November 2015
Article

Connexin43 knockdown in bone marrow‑derived dendritic cells by small interfering RNA leads to a diminished T-cell stimulation

Fuling Yu, Hui Yan, Wencheng Nie, Jianhua Zhu

Pages: 895-900 Published online on: 20 November 2015
Article

Lefty1 alleviates renal tubulointerstitial injury in mice with unilateral ureteral obstruction

Changgeng Xu, Mingwei Xu, Wei Wang, Jie Zhang

Pages: 901-908 Published online on: 30 November 2015
Article

Modulation of transforming growth factor‑β signaling transducers in colon adenocarcinoma cells induced by staphylococcal enterotoxin B

Abolfazl Akbari, Gholam Reza Mobini, Reza Maghsoudi, Javad Akhtari, Ebrahim Faghihloo, Zohreh Farahnejad

Pages: 909-914 Published online on: 23 November 2015
Article

Synthetic innate defense regulator peptide combination using CpG ODN as a novel adjuvant induces long‑lasting and balanced immune responses

Chao‑Heng Yu, Zi‑Chao Luo, Meng Li, Lian Lu, Zhan Li, Xiao‑Zhe Wu, Ying‑Zi Fan, Hai‑Long Zhang, Bai‑Ling Zhou, Yang Wan, Ke Men, Yao‑Mei Tian, Shuang Chen, Feng‑Jiao Yuan, Rong Xiang, Li Yang

Pages: 915-924 Published online on: 19 November 2015
Article

Indoleamine 2,3‑dioxygenase downregulates T‑cell receptor complex ζ‑chain and c‑Myc, and reduces proliferation, lactate dehydrogenase levels and mitochondrial glutaminase in human T‑cells

Theodoros Eleftheriadis, Georgios Pissas, Georgia Antoniadi, Konstantina Tsogka, Maria Sounidaki, Vassilios Liakopoulos, Ioannis Stefanidis

Pages: 925-932 Published online on: 20 November 2015
Article

CK0403, a 9‑aminoacridine, is a potent anti‑cancer agent in human breast cancer cells

Yuan‑Wan Sun, Kuen‑Yuan Chen, Chul‑Hoon Kwon, Kun‑Ming Chen

Pages: 933-938 Published online on: 23 November 2015
Article

Investigation of the antidepressant effects of exopolysaccharides obtained from Marasmius androsaceus fermentation in a mouse model

Jia Song, Gaoyang Xing, Jiaming Cao, Lirong Teng, Chenliang Li, Qingfan Meng, Jiahui Lu, Yulin Zhou, Yang Liu, Di Wang, Lesheng Teng

Pages: 939-946 Published online on: 19 November 2015
Article

Polymorphisms in the PE35 and PPE68 antigens in Mycobacterium tuberculosis strains may affect strain virulence and reflect ongoing immune evasion

Yi Jiang, Jianhao Wei, Haican Liu, Guilian Li, Qian Guo, Yan Qiu, Lili Zhao, Machao Li, Xiuqin Zhao, Xiangfeng Dou, Kanglin Wan

Pages: 947-954 Published online on: 19 November 2015
Article

Effects of hesperetin on platelet-derived growth factor-BB-induced pulmonary artery smooth muscle cell proliferation

Li Wei, Wei Deng, Zhihong Cheng, Haipeng Guo, Shihong Wang, Xiao Zhang, Yiyu He, Qizhu Tang

Pages: 955-960 Published online on: 30 November 2015
Article

Characterization of mitochondrial NADH dehydrogenase 1α subcomplex 10 variants in cardiac muscles from normal Wistar rats and spontaneously hypertensive rats: Implications in the pathogenesis of hypertension

Liying Huang, Xian Jin, Li Xia, Xiaoling Wang, Yun Yu, Cunfei Liu, Dongmin Shao, Ningyuan Fang, Chao Meng

Pages: 961-966 Published online on: 23 November 2015
Article

Inhibitory effect of withaferin A on Helicobacter pylori‑induced IL‑8 production and NF‑κB activation in gastric epithelial cells

Green Kim, Tae‑Hyoun Kim, Min‑Jung Kang, Jin‑A Choi, Da‑Young Pack, Ik‑Rae Lee, Min‑Gyu Kim, Sang‑Seop Han, Bo‑Yeon Kim, Sang‑Muk Oh, Kyung‑Bok Lee, Dong‑Jae Kim, Jong‑Hwan Park

Pages: 967-972 Published online on: 23 November 2015
Article

Astaxanthin reduces type 2 diabetic‑associated cognitive decline in rats via activation of PI3K/Akt and attenuation of oxidative stress

Xiaobin Li, Zhonghua Qi, Longshan Zhao, Zhan Yu

Pages: 973-979 Published online on: 25 November 2015
Article

Shensongyangxin protects against pressure overload‑induced cardiac hypertrophy

Di‑Fei Shen, Qing‑Qing Wu, Jian Ni, Wei Deng, Cong Wei, Zhen‑Hua Jia, Heng Zhou, Meng‑Qiao Zhou, Zhou‑Yan Bian, Qi‑Zhu Tang

Pages: 980-988 Published online on: 23 November 2015
Article

Effects of total flavones from Dendranthema morifolium on vasocontraction and proliferation of vascular smooth muscle cells

Hong‑Feng Jin, Xiao‑Wei Liu, Yi‑Ming Tang, Li‑Jiang Tang, Ya‑Li Wang, Chang‑Qing Du

Pages: 989-993 Published online on: 19 November 2015
Article

miR-362-3p targets nemo-like kinase and functions as a tumor suppressor in renal cancer cells

Xiaowen Zou, Jianhua Zhong, Jiaqiang Li, Zhengming Su, Yan Chen, Wanxin Deng, Yuchi Li, Siheng Lu, Youcheng Lin, Liya Luo, Zesong Li, Zhiming Cai, Aifa Tang

Pages: 994-1002 Published online on: 30 November 2015
Article

Inhibitory effects of tetrandrine on epidermal growth factor-induced invasion and migration in HT29 human colorectal adenocarcinoma cells

Chi‑Ting Horng, Jai‑Sing Yang, Jo‑Hua Chiang, Chi‑Cheng Lu, Chiu‑Fang Lee, Ni‑Na Chiang, Fu‑An Chen

Pages: 1003-1009 Published online on: 01 December 2015
Article

Lentivirus-mediated TNF-α gene silencing and overexpression of osteoprotegerin inhibit titanium particle-induced inflammatory response and osteoclastogenesis in vitro

Li Peng, Hongzhi Wang, Keguan Song, Hai Wang, Ping Liu

Pages: 1010-1018 Published online on: 27 November 2015
Article

Rhus javanica Linn protects against hydrogen peroxide‑induced toxicity in human Chang liver cells via attenuation of oxidative stress and apoptosis signaling

Chanjin Yoon, Sushruta Koppula, Seunghoon Yoo, Munjeong Yum, Jinseoub Kim, Jaedong Lee, Mindong Song

Pages: 1019-1025 Published online on: 23 November 2015
Article Open Access

Survivin is expressed in degenerated nucleus pulposus cells and is involved in proliferation and the prevention of apoptosis in vitro

Yazhou Lin, Bin Yue, Hongfei Xiang, Yong Liu, Xuexiao Ma, Bohua Chen

Pages: 1026-1032 Published online on: 23 November 2015
Article

MicroRNA‑145 inhibits the malignant phenotypes of gastric carcinoma cells via downregulation of fascin 1 expression Retraction in /10.3892/mmr.2022.12613

Minghui Xue, Lunde Zhao, Fang Yang, Zhenjuan Li, Guangyan Li

Pages: 1033-1039 Published online on: 24 November 2015
Article

Association between DNMT3L polymorphic variants and the risk of endometriosis-associated infertility

Adrianna Mostowska, Malgorzata Szczepańska, Przemyslaw Wirstlein, Jana Skrzypczak, Paweł P. Jagodziński

Pages: 1040-1046 Published online on: 30 November 2015
Article

Morphine-induced delayed pre-conditioning against anoxia/reoxygenation injury in pulmonary artery endothelial cells: The role of mitochondrial KATP channels Retraction in /10.3892/mmr.2023.13030

Wengang Ding, Yueping Guo, Xiaoguang Cui, Bing Zhang, Dongmei Li, Wenzhi Li

Pages: 1047-1053 Published online on: 30 November 2015
Correction Open Access

[Corrigendum] Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells

Dacai Xu, Jianglin Wang, Zhenkang Zhou, Zhiwei He, Qing Zhao

Pages: 1054-1054 Published online on: 20 November 2015
Correction Open Access

[Corrigendum] Naotaifang extract treatment results in increased ferroportin expression in the hippocampus of rats subjected to cerebral ischemia

Jun Liao, Xing Xia, Guo‑Zuo Wang, Yong‑Mei Shi, Jin‑Wen Ge

Pages: 1055-1055 Published online on: 30 November 2015
Correction Open Access

[Corrigendum] NADPH oxidase 3-associated oxidative stress and caspase 3-dependent apoptosis in the cochleae of D-galactose-induced aged rats

Zhengde Du, Shuo Li, Lin Liu, Qiong Yang, Hongwei Zhang, Chunsheng Gao

Pages: 1056-1056 Published online on: 20 November 2015
Journal Cover

January-2016
Volume 13 Issue 1

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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