|
1
|
Garbe C, Peris K, Hauschild A, et al:
Diagnosis and treatment of melanoma: European consensus-based
interdisciplinary guideline. Eur J Cancer. 46:270–283. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Festino L, Fabozzi A, Manzo A, Gambardella
V, Martinelli E, Troiani T, De Vita F, Orditura M, Ciardiello F and
Morgillo F: Critical appraisal of the use of regorafenib in the
management of colorectal cancer. Cancer Manag Res. 5:49–55.
2013.PubMed/NCBI
|
|
3
|
Thalayasingam M, Davies LJ, Llanora GV,
Gerez IF, Van Bever HP and Shek LP: Clinical characteristics and
outcomes of patients undergoing drug provocation tests (DPTs). Ann
Acad Med Singapore. 42:184–189. 2013.PubMed/NCBI
|
|
4
|
Hofheinz RD, Heinemann V, von Weikersthal
LF, Laubender RP, Gencer D, Burkholder I, Hochhaus A and Stintzing
S: Capecitabine-associated hand-foot-skin reaction is an
independent clinical predictor of improved survival in patients
with colorectal cancer. Br J Cancer. 107:1678–1683. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Abou Youssif T, Fahmy MA, Koumakpayi IH,
Ayala F, Al Marzooqi S, Chen G, Tamboli P, Squire J, Tanguay S and
Sircar K: The mammalian target of rapamycin pathway is widely
activated without PTEN deletion in renal cell carcinoma metastases.
Cancer. 117:290–300. 2011.PubMed/NCBI
|
|
6
|
Qian CN, Furge KA, Knol J, et al:
Activation of the PI3K/AKT pathway induces urothelial carcinoma of
the renal pelvis: identification in human tumors and confirmation
in animal models. Cancer Res. 69:8256–8264. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Foster JG, Blunt MD, Carter E and Ward SG:
Inhibition of PI3K signaling spurs new therapeutic opportunities in
inflammatory/autoimmune diseases and hematological malignancies.
Pharmacol Rev. 64:1027–1054. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Shi ZM, Wang XF, Qian X, et al: MiRNA-181b
suppresses IGF-1R and functions as a tumor suppressor gene in
gliomas. RNA. 19:552–560. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ponnurangam S, Standing D, Rangarajan P
and Subramaniam D: Tandutinib inhibits the Akt/mTOR signaling
pathway to inhibit colon cancer growth. Mol Cancer Ther.
12:598–609. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Wang X, Jiao F, Wang QW, Wang J, Yang K,
Hu RR, Liu HC, Wang HY and Wang YS: Aged black garlic extract
induces inhibition of gastric cancer cell growth in vitro
and in vivo. Mol Med Rep. 5:66–72. 2012.PubMed/NCBI
|
|
11
|
Rajput S and Mandal M: Antitumor promoting
potential of selected phytochemicals derived from spices: a review.
Eur J Cancer Prev. 21:205–215. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Cha JH, Choi YJ, Cha SH, Choi CH and Cho
WH: Allicin inhibits cell growth and induces apoptosis in U87MG
human glioblastoma cells through an ERK-dependent pathway. Oncol
Rep. 28:41–48. 2012.PubMed/NCBI
|
|
13
|
Shirzad H, Taji F and Rafieian-Kopaei M:
Correlation between antioxidant activity of garlic extracts and
WEHI-164 fibrosarcoma tumor growth in BALB/c mice. J Med Food.
14:969–974. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kaschula CH, Hunter R, Stellenboom N, et
al: Structure-activity studies on the anti-proliferation activity
of ajoene analogues in WHCO1 oesophageal cancer cells. Eur J Med
Chem. 50:236–254. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Hammoud SS, Cairns BR and Jones DA:
Epigenetic regulation of colon cancer and intestinal stem cells.
Curr Opin Cell Biol. 25:177–183. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Stemke-Hale K, Gonzalez-Angulo AM, Lluch
A, et al: An integrative genomic and proteomic analysis of PIK3CA,
PTEN, and AKT mutations in breast cancer. Cancer Res. 68:6084–6091.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Squarize CH, Castilho RM, Abrahao AC,
Molinolo A, Lingen MW and Gutkind JS: PTEN deficiency contributes
to the development and progression of head and neck cancer.
Neoplasia. 15:461–471. 2013.PubMed/NCBI
|
|
18
|
Sansal I and Sellers WR: The biology and
clinical relevance of the PTEN tumor suppressor pathway. J Clin
Oncol. 22:2954–2963. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhang P, Chen JH and Guo XL: New insights
into PTEN regulation mechanisms and its potential function in
targeted therapies. Biomed Pharmacother. 66:485–490. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Carpenter RL, Jiang Y, Jing Y, He J,
Rojanasakul Y, Liu LZ and Jiang BH: Arsenite induces cell
transformation by reactive oxygen species, AKT, ERK1/2, and
p70S6K1. Biochem Biophys Res Commun. 414:533–538. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Vander Haar E, Lee SI, Bandhakavi S,
Griffin TJ and Kim DH: Insulin signalling to mTOR mediated by the
Akt/PKB substrate PRAS40. Nat Cell Biol. 9:316–323. 2007.PubMed/NCBI
|
|
22
|
Qian Y, Corum L, Meng Q, Blenis J, Zheng
JZ, Shi X, Flynn DC and Jiang BH: PI3K induced actin filament
remodeling through Akt and p70S6K1: implication of essential role
in cell migration. Am J Physiol Cell Physiol. 286:C153–C163. 2004.
View Article : Google Scholar : PubMed/NCBI
|
