|
1
|
Gualtierotti R, Biggioggero M, Penatti AE
and Meroni PL: Updating on the pathogenesis of systemic lupus
erythematosus. Autoimmun Rev. 10:3–7. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Rahman A and Isenberg DA: Systemic lupus
erythematosus. N Engl J Med. 358:929–939. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Harley IT, Kaufman KM, Langefeld CD,
Harley JB and Kelly JA: Genetic susceptibility to SLE, New insights
from fine mapping and genome-wide association studies. Nat Rev
Genet. 10:285–290. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Sestak AL, Fürnrohr BG, Harley JB, Merrill
JT and Namjou B: The genetics of systemic lupus erythematosus and
implications for targeted therapy. Ann Rheum Dis. 70((Suppl 1)):
i37–i43. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Mak A and Tay SH: Environmental factors
toxicants and systemic lupus erythematosus. Int J Mol Sci.
15:16043–16056. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Rigante D, Mazzoni MB and Esposito S: The
cryptic interplay between systemic lupus erythematosus and
infections. Autoimmun Rev. 13:96–102. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Sparks JA and Costenbader KH: Genetics,
environment, and gene-environment interactions in the development
of systemic rheumatic diseases. Rheum Dis Clin North Am.
40:637–657. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Zan H: Epigenetics in lupus. Autoimmunity.
47:213–214. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Richardson B: Impact of aging on DNA
methylation. Ageing Res Rev. 2:245–261. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Egger G, Liang G, Aparicio A and Jones PA:
Epigenetics in human disease and prospects for epigenetic therapy.
Nature. 429:457–463. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Robertson KD: DNA methylation and human
disease. Nat Rev Genet. 6:597–610. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Richardson B, Scheinbart L, Strahler J,
Gross L, Hanash S and Johnson M: Evidence for impaired T cell DNA
methylation in systemic lupus erythematosus and rheumatoid
arthritis. Arthritis Rheum. 33:1665–1673. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Lu Q, Kaplan M, Ray D, Ray D, Zacharek S,
Gutsch D and Richardson B: Demethylation of ITGAL (CD11a)
regulatory sequences in systemic lupus erythematosus. Arthritis
Rheum. 46:1282–1291. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Oelke K, Lu Q, Richardson D, Wu A, Deng C,
Hanash S and Richardson B: Overexpression of CD70 and
overstimulation of IgG synthesis by lupus T cells and T cells
treated with DNA methylation inhibitors. Arthritis Rheum.
50:1850–1860. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Richardson B: Primer: E pigenetics of
autoimmunity. Nat Clin Pract Rheumatol. 3:521–527. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Basu D, Liu Y, Wu A, Yarlagadda S, Gorelik
GJ, Kaplan MJ, Hewagama A, Hinderer RC, Strickland FM and
Richardson BC: Stimulatory and inhibitory killer Ig-like receptor
molecules are expressed and functional on lupus T cells. J Immunol.
183:3481–3487. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lei W, Luo Y, Lei W, Luo Y, Yan K, Zhao S,
Li Y, Qiu X, Zhou Y, Long H, et al: Abnormal DNA methylation in
CD4+ T cells from patients with systemic lupus
erythematosus, systemic sclerosis, and dermatomyositis. Scand J
Rheumatol. 38:369–374. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lu Q, Wu A, Tesmer L, Ray D, Yousif N and
Richardson B: Demethylation of CD40LG on the inactive X in T cells
from women with lupus. J Immunol. 179:6352–6358. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Hewagama A, Gorelik G, Patel D,
Liyanarachchi P, McCune WJ, Somers E, Gonzalez-Rivera T, Strickland
F and Richardson B: Michigan Lupus Cohort. Overexpression of
X-linked genes in T cells from women with lupus. J Autoimmun.
41:60–71. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Jeffries MA, Dozmorov M, Tang Y, Merrill
JT, Wren JD and Sawalha AH: Genome-wide DNA methylation patterns in
CD4+ T cells from patients with systemic lupus
erythematosus. Epigenetics. 6:593–601. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Coit P, Jeffries M, Altorok N, Dozmorov
MG, Koelsch KA, Wren JD, Merrill JT, McCune WJ and Sawalha AH:
Genome-wide DNA methylation study suggests epigenetic accessibility
and transcriptional poising of interferon-regulated genes in naïve
CD4+ T cells from lupus patients. J Autoimmun. 43:78–84.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Chung SA, Nititham J, Elboudwarej E, Quach
HL, Taylor KE, Barcellos LF and Criswell LA: Genome-wide assessment
of differential DNA methylation associated with autoantibody
production in systemic lupus erythematosus. PLoS One.
10:e01298132015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Chan RW, Jiang P, Peng X, Tam LS, Liao GJ,
Li EK, Wong PC, Sun H, Chan KC, Chiu RW, et al: Plasma DNA
aberrations in systemic lupus erythematosus revealed by genomic and
methylomic sequencing. Proc Natl Acad Sci USA. 111:E5302–E5311.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Jenuwein T and Allis CD: Translating the
histone code. Science. 293:1074–1080. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Javierre BM, Fernandez AF, Richter J,
Al-Shahrour F, Martin-Subero JI, Rodriguez-Ubreva J, Berdasco M,
Fraga MF, O'Hanlon TP, Rider LG, et al: Changes in the pattern of
DNA methylation associate with twin discordance in systemic lupus
erythematosus. Genome Res. 20:170–179. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Zhang Z, Song L, Maurer K, Petri MA and
Sullivan KE: Global H4 acetylation analysis by ChIP-chip in
systemic lupus erythematosus monocytes. Genes Immun. 11:124–133.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Pieterse E, Hofstra J, Berden J, Herrmann
M, Dieker J and van der Vlag J: Acetylated histones contribute to
the immunostimulatory potential of neutrophil extracellular traps
in systemic lupus erythematosus. Clin Exp Immunol. 179:68–74. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Mamula MJ, Gee RJ, Elliott JI, Sette A,
Southwood S, Jones PJ and Blier PR: Isoaspartyl post-translational
modification triggers autoimmune responses to self-proteins. J Biol
Chem. 274:22321–22327. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Doyle HA, Aswad DW and Mamula MJ:
Autoimmunity to isomerized histone H2B in systemic lupus
erythematosus. Autoimmunity. 46:6–13. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Liu CL, Tangsombatvisit S, Rosenberg JM,
Mandelbaum G, Gillespie EC, Gozani OP, Alizadeh AA and Utz PJ:
Specific post-translational histone modifications of neutrophil
extracellular traps as immunogens and potential targets of lupus
autoantibodies. Arthritis Res Ther. 14:R252012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Apostolidis SA, Rauen T, Hedrich CM,
Tsokos GC and Crispín JC: Protein phosphatase 2A enables expression
of interleukin 17 (IL-17) through chromatin remodeling. J Biol
Chem. 288:26775–26784. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
White CA, Pone EJ, Lam T, Tat C, Hayama
KL, Li G, Zan H and Casali P: Histone deacetylase inhibitors
upregulate B cell microRNAs that silence AID and Blimp-1 expression
for epigenetic modulation of antibody and autoantibody responses. J
Immunol. 193:5933–5950. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Regna NL, Chafin CB, Hammond SE,
Puthiyaveetil AG, Caudell DL and Reilly CM: Class I and II histone
deacetylase inhibition by ITF2357 reduces SLE pathogenesis in vivo.
Clin Immunol. 151:29–42. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Yang Y, Tang Q, Zhao M, Liang G, Wu H, Li
D, Xie Y, Tan Y, Dai Y, Yung S, et al: The effect of mycophenolic
acid on epigenetic modifications in lupus CD4+ T cells.
Clin Immunol. 158:67–76. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Mir AR: Moinuddin: G lyoxidation of
histone proteins in autoimmune disorders. Clin Chim Acta.
450:25–30. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Khan MA and Dixit K: Moinuddin,A rif Z and
Alam K: Studies on peroxynitrite-modified H1 histone: Implications
in systemic lupus erythematosus. Biochimie. 97:104–113. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Alzolibani AA, Al Robaee AA, Al-Shobaili
HA and Rasheed Z: 4-Hydroxy-2-nonenal modified histone-H2A: A
possible antigenic stimulus for systemic lupus erythematosus
autoantibodies. Cell Immunol. 284:154–162. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Moran VA, Perera RJ and Khalil AM:
Emerging functional and mechanistic paradigms of mammalian long
non-coding RNAs. Nucleic Acids Res. 40:6391–6400. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Ørom UA, Derrien T, Beringer M, Gumireddy
K, Gardini A, Bussotti G, Lai F, Zytnicki M, Notredame C, Huang Q,
et al: Long noncoding RNAs with enhancer-like function in human
cells. Cell. 143:46–58. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Sun L, Goff LA, Trapnell C, Alexander R,
Lo KA, Hacisuleyman E, Sauvageau M, Tazon-Vega B, Kelley DR,
Hendrickson DG, et al: Long noncoding RNAs regulate adipogenesis.
Proc Natl Acad Sci USA. 110:3387–3392. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Davis-Dusenbery BN and Hata A: Mechanisms
of control of microRNA biogenesis. J Biochem. 148:381–392.
2010.PubMed/NCBI
|
|
42
|
Dai Y, Huang YS, Tang M, Lv TY, Hu CX, Tan
YH, Xu ZM and Yin YB: Microarray analysis of microRNA expression in
peripheral blood cells of systemic lupus erythematosus patients.
Lupus. 16:939–946. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Tang Y, Luo X, Cui H, Ni X, Yuan M, Guo Y,
Huang X, Zhou H, de Vries N, Tak PP, et al: MicroRNA-146A
contributes to abnormal activation of the type I interferon pathway
in human lupus by targeting the key signaling proteins. Arthritis
Rheum. 60:1065–1075. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Deng Y, Zhao J, Sakurai D, Kaufman KM,
Edberg JC, Kimberly RP, Kamen DL, Gilkeson GS, Jacob CO, Scofield
RH, et al: MicroRNA-3148 modulates allelic expression of toll-like
receptor 7 variant associated with systemic lupus erythematosus.
PLoS Genet. 9:e10033362013. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Zhao X, Tang Y, Qu B, Cui H, Wang S, Wang
L, Luo X, Huang X, Li J, Chen S, et al: MicroRNA-125a contributes
to elevated inflammatory chemokine RANTES levels via targeting
KLF13 in systemic lupus erythematosus. Arthritis Rheum.
62:3425–3435. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Chauhan SK, Singh VV, Rai R, Rai M and Rai
G: Differential microRNA profile and post-transcriptional
regulation exist in systemic lupus erythematosus patients with
distinct autoantibody specificities. J Clin Immunol. 34:491–503.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Te JL, Dozmorov IM, Guthridge JM, Nguyen
KL, Cavett JW, Kelly JA, Bruner GR, Harley JB and Ojwang JO:
Identification of unique microRNA signature associated with lupus
nephritis. PLoS One. 5:e103442010. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Pan W, Zhu S, Yuan M, Cui H, Wang L, Luo
X, Li J, Zhou H, Tang Y and Shen N: MicroRNA-21 and microRNA-148a
contribute to DNA hypomethylation in lupus CD4+ T cells
by directly and indirectly targeting DNA methyltransferase 1. J
Immunol. 184:6773–6781. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Zhao S, Wang Y, Liang Y, Zhao M, Long H,
Ding S, Yin H and Lu Q: MicroRNA-126 regulates DNA methylation in
CD4+ T cells and contributes to systemic lupus
erythematosus by targeting DNA methyltransferase 1. Arthritis
Rheum. 63:1376–1386. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Garchow BG, Bartulos Encinas O, Leung YT,
Tsao PY, Eisenberg RA, Caricchio R, Obad S, Petri A, Kauppinen S
and Kiriakidou M: Silencing of microRNA-21 in vivo ameliorates
autoimmune splenomegaly in lupus mice. EMBO Mol Med. 3:605–615.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Stagakis E, Bertsias G, Verginis P, Nakou
M, Hatziapostolou M, Kritikos H, Iliopoulos D and Boumpas DT:
Identification of novel microRNA signatures linked to human lupus
disease activity and pathogenesis, miR-21 regulates aberrant T cell
responses through regulation of PDCD4 expression. Ann Rheum Dis.
70:1496–1506. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Perkel JM: Visiting ‘noncodarnia’.
Biotechniques. 54(301): 303–304. 2013.
|
|
53
|
Kaikkonen MU, Lam MT and Glass CK:
Non-coding RNAs as regulators of gene expression and epigenetics.
Cardiovasc Res. 90:430–440. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Fitzgerald KA and Caffrey DR: Long
noncoding RNAs in innate and adaptive immunity. Curr Opin Immunol.
26:140–146. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Liu CC, Kao AH, Manzi S and Ahearn JM:
Biomarkers in systemic lupus erythematosus, Challenges and
prospects for the future. Ther Adv Musculoskelet Dis. 5:210–233.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Wu Y, Zhang F, Ma J, Zhang X, Wu L, Qu B,
Xia S, Chen S, Tang Y and Shen N: Association of large intergenic
noncoding RNA expression with disease activity and organ damage in
systemic lupus erythematosus. Arthritis Res Ther. 17:1312015.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Haywood ME, Rose SJ, Horswell S, Lees MJ,
Fu G, Walport MJ and Morley BJ: Overlapping BXSB congenic
intervals, in combination with microarray gene expression, reveal
novel lupus candidate genes. Genes Immun. 7:250–263. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Suarez-Gestal M, Calaza M, Endreffy E,
Pullmann R, Ordi-Ros J, Sebastiani GD, Ruzickova S, Santos Jose M,
Papasteriades C, Marchini M, et al: European Consortium of SLE DNA
Collections: Replication of recently identified systemic lupus
erythematosus genetic associations: A case-control study. Arthritis
Res Ther. 11:R692009. View
Article : Google Scholar : PubMed/NCBI
|
|
59
|
Kino T, Hurt DE, Ichijo T, Nader N and
Chrousos GP: Noncoding RNA gas5 is a growth arrest- and
starvation-associated repressor of the glucocorticoid receptor. Sci
Signal. 3:ra82010. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Yacqub-Usman K, Pickard MR and Williams
GT: Reciprocal regulation of GAS5 lncRNA levels and mTOR inhibitor
action in prostate cancer cells. Prostate. 75:693–705. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Gomez JA, Wapinski OL, Yang YW, Bureau JF,
Gopinath S, Monack DM, Chang HY, Brahic M and Kirkegaard K: The
NeST long ncRNA controls microbial susceptibility and epigenetic
activation of the interferon-γ locus. Cell. 152:743–754. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Masutani K, Taniguchi M, Nakashima H, et
al: Upregulated interleukin-4 production by peripheral T-helper
cells in idiopathic membranous nephropathy. Nephrol Dial
Transplant. 19:580–586. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Chan RW, Lai FM, Li EK, et al: Intrarenal
cytokine gene expression in lupus nephritis. Ann Rheum Dis.
66:886–892. 2007. View Article : Google Scholar : PubMed/NCBI
|