Aspergillus in liquid‑based cervicovaginal cytology in a postmenopausal patient: A case report

Garza‑Guajardo,Raquel; Canales‑Martínez,Luis   Carlos; Rodríguez‑Sánchez,Irám   Pablo; Sánchez‑Chaparro,María   Marisela; Gómez-Macías,Gabriela   Sofía; Vilches-Cisneros,Natalia; Barboza-Quintana,Oralia

doi:10.3892/br.2017.974

October-2017 Volume 7 Issue 4

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October-2017 Volume 7 Issue 4

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Case Report

Aspergillus in liquid‑based cervicovaginal cytology in a postmenopausal patient: A case report

Authors:
- Raquel Garza‑Guajardo
- Luis Carlos Canales‑Martínez
- Irám Pablo Rodríguez‑Sánchez
- María Marisela Sánchez‑Chaparro
- Gabriela Sofía Gómez-Macías
- Natalia Vilches-Cisneros
- Oralia Barboza-Quintana
View Affiliations / Copyright

Affiliations: Department of Pathological Anatomy and Cytopathology, Universidad Autonoma de Nuevo Leon, Hospital Universitario ‘Dr José Eleuterio González’, Monterrey, Nuevo León 64460, Mexico, Department of Genetics, Universidad Autonoma de Nuevo Leon, College of Medicine, Monterrey, Nuevo León 64460, Mexico, Laboratory of Immunology and Virology, Universidad Autonoma de Nuevo Leon, College of Biological Sciences, San Nicolás de los Garza, Nuevo León 66450, Mexico
Pages: 306-308
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Published online on: August 25, 2017

https://doi.org/10.3892/br.2017.974
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Abstract

Aspergillus is an opportunistic fungus present in humid environments, whose natural environment is in soil, hay and compost. It is a frequent contaminant in the clinical laboratory. Because of this, the fungus is often inhaled, affecting those with an underlying pulmonary disease or immune deficiency. Fungal genitourinary tract infections are relatively common. A rare Aspergillus spp cervical infection diagnosed via liquid‑based cytology is presented in the current study. The 57‑year‑old woman attended her annual check‑up without any relevant medical history. The result of a gynecological examination by Papanicolaou smear was normal and routine liquid‑based cytology was performed. The specimen exhibited fungal organisms characterized by septate hyphae branching at acute angles, most consistent with the Aspergillus species. Subsequent cytology demonstrated the same results. Antifungal treatment was initiated and a second post‑treatment smear only exhibited atrophy. The cytomorphological features of Aspergillus spp. are discussed in the current study and a brief review of the few reported cases of a primary cervical infection in the literature is provided. In addition, the liquid‑based cytology was established as a tool to diagnose the rare Aspergillus infection.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Aspergillus in liquid‑based cervicovaginal cytology in a postmenopausal patient: A case report

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