Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
September-2020 Volume 13 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September-2020 Volume 13 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Acute myocardial infarction with cardiogenic shock in a young physically active physician concurrently using the anabolic steroid sustanon: A case report

  • Authors:
    • Nasr Alrabadi
    • Mohamad Ismail Jarrah
    • Karem Hasan Alzoubi
  • View Affiliations / Copyright

    Affiliations: Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan, Department of Internal Medicine, Interventional Cardiology Division, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan, Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan
  • Article Number: 14
    |
    Published online on: June 26, 2020
       https://doi.org/10.3892/br.2020.1321
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The association between ischemic heart disease (IHD) and the concurrent use of anabolic androgenic steroids (AASs) is underestimated in clinical settings. The tendency of patients to not disclose AASs use may explain this underestimation. In the present case report, the clinical case of a 26‑year‑old physically active male, who was a physician, without any classical coronary risk factors, who presented with chest pain that was misdiagnosed by the peripheral care unit as skeletal muscle pain is described. Later, the patient was brought to our central hospital (King Abdullah University Hospital) suffering from a massive acute myocardial infarction with marked ECG changes and cardiogenic shock. Following stabilization of his condition, a detailed history of the patient was taken, during which the patient admitted that he was a chronic user of the anabolic steroid sustanon (250 mg, once/week for 6 months) and amino acid supplements (whey protein isolate, 6 tabs every day for 1 year). Specific cardiac markers were increased and the patient exhibited dynamic ischemic changes in his electrocardiogram. Notably, the coronary angiogram of the patient demonstrated ostial occlusion of the left anterior descending artery, which was associated with mid‑right coronary artery embolic obstruction. Other than the anabolic steroids and protein supplementation use, the patient history, examination and lab evaluation were normal. During follow up, the patient continued to suffer heart failure with low ejection fraction. In addition, he developed apical thrombus 2 months after primary admission. The patient developed tachycardia in spite of optimal medical treatment and finally received an implantable cardioverter defibrillator. Physicians should always be aware of the possibility of AASs use in young physically active patients. IHD should always be suspected and investigated with typical chest pain in healthy young patients, even if regular risk factors are not present. Medical professionals should not be excluded as potential AASs users/abusers.
View Figures

Figure 1

Figure 2

View References

1 

Santos RP, Pereira A, Guedes H, Lourenço C, Azevedo J and Pinto P: Anabolic drugs and myocardial infarction-a clinical case report. Arq Bras Cardiol. 105:316–319. 2015.PubMed/NCBI View Article : Google Scholar : (In English, Portuguese).

2 

Stergiopoulos K, Brennan JJ, Mathews R, Setaro JF and Kort S: Anabolic steroids, acute myocardial infarction and polycythemia: A case report and review of the literature. Vasc Health Risk Manag. 4:1475–1480. 2008.PubMed/NCBI View Article : Google Scholar

3 

Luijkx T, Velthuis BK, Backx FJ, Buckens CF, Prakken NH, Rienks R, Mali WP and Cramer MJ: Anabolic androgenic steroid use is associated with ventricular dysfunction on cardiac MRI in strength trained athletes. Int J Cardiol. 167:664–668. 2013.PubMed/NCBI View Article : Google Scholar

4 

Kersey RD, Elliot DL, Goldberg L, Kanayama G, Leone JE, Pavlovich M and Pope HG Jr: National Athletic Trainers' Association. National athletic trainers' association position statement: Anabolic-androgenic steroids. J Athl Train. 47:567–588. 2012.PubMed/NCBI View Article : Google Scholar

5 

Christou GA, Christou KA, Nikas DN and Goudevenos JA: Acute myocardial infarction in a young bodybuilder taking anabolic androgenic steroids: A case report and critical review of the literature. Eur J Prev Cardiol. 23:1785–1796. 2016.PubMed/NCBI View Article : Google Scholar

6 

Peoples K, Kobe D, Campana C and Simon E: Hyperhomocysteinemia-induced myocardial infarction in a young male using anabolic steroids. Am J Emerg Med. 32:948.e1–2. 2014.PubMed/NCBI View Article : Google Scholar

7 

Ilhan E, Demirci D, Güvenç TS and Calık AN: Acute myocardial infarction and renal infarction in a bodybuilder using anabolic steroids. Turk Kardiyol Dern Ars. 38:275–278. 2010.PubMed/NCBI

8 

Wysoczanski M, Rachko M and Bergmann SR: Acute myocardial infarction in a young man using anabolic steroids. Angiology. 59:376–378. 2008.PubMed/NCBI View Article : Google Scholar

9 

Hartgens F, Rietjens G, Keizer HA, Kuipers H and Wolffenbuttel BH: Effects of androgenic-anabolic steroids on apolipoproteins and lipoprotein (a). Br J Sports Med. 38:253–259. 2004.PubMed/NCBI View Article : Google Scholar

10 

Fineschi V, Riezzo I, Centini F, Silingardi E, Licata M, Beduschi G and Karch SB: Sudden cardiac death during anabolic steroid abuse: Morphologic and toxicologic findings in two fatal cases of bodybuilders. Int J Legal Med. 121:48–53. 2007.PubMed/NCBI View Article : Google Scholar

11 

Kennedy MC, Corrigan AB and Pilbeam ST: Myocardial infarction and cerebral haemorrhage in a young body builder taking anabolic steroids. Aust N Z J Med. 23(713)1993.PubMed/NCBI View Article : Google Scholar

12 

Lyngberg KK: Myocardial infarction and death of a body builder after using anabolic steroids. Ugeskr Laeger. 153:587–588. 1991.PubMed/NCBI(In Danish).

13 

Pilo R, Aharony D and Raz A: Testosterone potentiation of ionophore and ADP induced platelet aggregation: Relationship to arachidonic acid metabolism. Thromb Haemost. 46:538–542. 1981.PubMed/NCBI

14 

Kokkonen L, Anttonen O, Penttilä O and Voutilainen S: Protein C deficiency and use of anabolic steroids behind the myocardial infarction in a young man. Duodecim. 117:2279–2281. 2001.PubMed/NCBI(In Finnish).

15 

Buttner A, Sachs H, Mall G, Tutsch-Bauer E and Weis S: Progressive idiopathic bilateral striato-pallido-dentate calcinosis (Fahr's disease) in a person with anabolic steroid abuse. Leg Med (Tokyo). 3:114–118. 2001.PubMed/NCBI View Article : Google Scholar

16 

Sonmez E, Turkdogan KA, Yilmaz C, Kucukbuzcu S, Ozkan A and Sogutt O: Chronic anabolic androgenic steroid usage associated with acute coronary syndrome in bodybuilder. Turk J Emerg Med. 16:35–37. 2016.PubMed/NCBI View Article : Google Scholar

17 

Skogastierna C, Hotzen M, Rane A and Ekström L: A supraphysiological dose of testosterone induces nitric oxide production and oxidative stress. Eur J Prev Cardiol. 21:1049–1054. 2014.PubMed/NCBI View Article : Google Scholar

18 

Tischer KH, Heyny-von Haussen R, Mall G and Doenecke P: Coronary thrombosis and ectasia of coronary arteries after long-term use of anabolic steroids. Z Kardiol. 92:326–331. 2003.PubMed/NCBI View Article : Google Scholar : (In German).

19 

Phillis BD, Abeywardena MY, Adams MJ, Kennedy JA and Irvine RJ: Nandrolone potentiates arrhythmogenic effects of cardiac ischemia in the rat. Toxicol Sci. 99:605–611. 2007.PubMed/NCBI View Article : Google Scholar

20 

Sculthorpe N, Grace F, Jones P and Davies B: Evidence of altered cardiac electrophysiology following prolonged androgenic anabolic steroid use. Cardiovasc Toxicol. 10:239–243. 2010.PubMed/NCBI View Article : Google Scholar

21 

Maior AS, Carvalho AR, Marques-Neto SR, Menezes P, Soares PP and Nascimento JH: Cardiac autonomic dysfunction in anabolic steroid users. Scand J Med Sci Sports. 23:548–555. 2013.PubMed/NCBI View Article : Google Scholar

22 

Kasikcioglu E, Oflaz H, Umman B and Bugra Z: Androgenic anabolic steroids also impair right ventricular function. Int J Cardiol. 134:123–125. 2009.PubMed/NCBI View Article : Google Scholar

23 

Frati P, Busardò FP, Cipolloni L, Dominicis ED and Fineschi V: Anabolic androgenic steroid (AAS) related deaths: Autoptic, histopathological and toxicological findings. Curr Neuropharmacol. 13:146–159. 2015.PubMed/NCBI View Article : Google Scholar

24 

Gheshlaghi F, Piri-Ardakani MR, Masoumi GR, Behjati M and Paydar P: Cardiovascular manifestations of anabolic steroids in association with demographic variables in body building athletes. J Res Med Sci. 20:165–168. 2015.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Alrabadi N, Jarrah MI and Alzoubi KH: Acute myocardial infarction with cardiogenic shock in a young physically active physician concurrently using the anabolic steroid sustanon: A case report. Biomed Rep 13: 14, 2020.
APA
Alrabadi, N., Jarrah, M.I., & Alzoubi, K.H. (2020). Acute myocardial infarction with cardiogenic shock in a young physically active physician concurrently using the anabolic steroid sustanon: A case report. Biomedical Reports, 13, 14. https://doi.org/10.3892/br.2020.1321
MLA
Alrabadi, N., Jarrah, M. I., Alzoubi, K. H."Acute myocardial infarction with cardiogenic shock in a young physically active physician concurrently using the anabolic steroid sustanon: A case report". Biomedical Reports 13.3 (2020): 14.
Chicago
Alrabadi, N., Jarrah, M. I., Alzoubi, K. H."Acute myocardial infarction with cardiogenic shock in a young physically active physician concurrently using the anabolic steroid sustanon: A case report". Biomedical Reports 13, no. 3 (2020): 14. https://doi.org/10.3892/br.2020.1321
Copy and paste a formatted citation
x
Spandidos Publications style
Alrabadi N, Jarrah MI and Alzoubi KH: Acute myocardial infarction with cardiogenic shock in a young physically active physician concurrently using the anabolic steroid sustanon: A case report. Biomed Rep 13: 14, 2020.
APA
Alrabadi, N., Jarrah, M.I., & Alzoubi, K.H. (2020). Acute myocardial infarction with cardiogenic shock in a young physically active physician concurrently using the anabolic steroid sustanon: A case report. Biomedical Reports, 13, 14. https://doi.org/10.3892/br.2020.1321
MLA
Alrabadi, N., Jarrah, M. I., Alzoubi, K. H."Acute myocardial infarction with cardiogenic shock in a young physically active physician concurrently using the anabolic steroid sustanon: A case report". Biomedical Reports 13.3 (2020): 14.
Chicago
Alrabadi, N., Jarrah, M. I., Alzoubi, K. H."Acute myocardial infarction with cardiogenic shock in a young physically active physician concurrently using the anabolic steroid sustanon: A case report". Biomedical Reports 13, no. 3 (2020): 14. https://doi.org/10.3892/br.2020.1321
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team