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Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience

  • Authors:
    • Vlad Vunvulea
    • Bogdan Andrei Suciu
    • Iuliu Gabriel Cocuz
    • Nicolae Bacalbașa
    • Călin Molnar
    • Dana Valentina Ghiga
    • Ioana Hălmaciu
  • View Affiliations / Copyright

    Affiliations: Medicine and Pharmacy Doctoral School, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, 540142 Târgu Mureş, Romania, Anatomy Department, University of Medicine and Pharmacy of Târgu Mureş, 540139 Târgu Mureş, Romania, Department of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Surgery, George Emil Palade University of Medicine, Pharmacy Science and Technology, 540142 Târgu Mureş, Romania, Department of Methodology of Scientific Research, George Emil Palade University of Medicine, Pharmacy Science and Technology, 540142 Târgu Mureş, Romania
    Copyright: © Vunvulea et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 80
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    Published online on: August 17, 2022
       https://doi.org/10.3892/br.2022.1563
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Abstract

Abdominal trauma is a common diagnosis for patients admitted to the emergency room. Evaluation of the severity of such patients can sometimes be difficult due to rapid hemodynamic changes caused by the activation of inflammatory and anti‑inflammatory regulatory mechanisms. To evaluate the prognosis of trauma patients, it is crucial to identify these changes and adapt various treatment strategies. Using the records of the Mures County Emergency Clinical Hospital, 126 patients were included in the present study with traumatic splenic injury admitted over 6 years. Blood parameters such as the neutrophil, lymphocyte, and platelet counts, the neutrophil to lymphocyte ratio (NLR), and the platelet to lymphocyte ratio (PLR) were determined, and the association between these and the severity of the traumatic injury [quantified as the injury severity score (ISS)] was calculated. We used linear and multiple regression analyses to identify and quantify the relationships. We found statistically significant associations between the ISS and the NLR (P=0.002), with an AUC of 0.816 and a cut‑off value of NLR=6.075 (sensitivity=76.7%, specificity=74.3%), and between the ISS and hemoglobin (P<0.0001), hematocrit (P<0.0001), neutrophil count (P<0.0001), lymphocyte count (P=0.0224), and platelet count (P=0.0163). No association was found between the PLR and the severity of trauma. An elevated NLR at admission in trauma patients had significant predictive power for the severity of trauma. Patients with an NLR greater than the cut‑off value of 6.075 were more likely to have suffered serious injuries and undergone deterioration.
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1 

Haan JM, Bochicchio GV, Kramer N and Scalea TM: Nonoperative Management of Blunt Splenic Injury: A 5-Year Experience. J Trauma. 58:492–498. 2005.PubMed/NCBI View Article : Google Scholar

2 

Subedi N, Yadav BN, Jha S, Paudel IS and Regmi R: A profile of abdominal and pelvic injuries in medico-legal autopsy. J Forensic Leg Med. 20:792–796. 2013.PubMed/NCBI View Article : Google Scholar

3 

Girard E, Abba J, Cristiano N, Siebert M, Barbois S, Létoublon C and Arvieux C: Management of splenic and pancreatic trauma. J Visc Surg. 153 (Suppl 4):S45–S60. 2016.PubMed/NCBI View Article : Google Scholar

4 

Bulut F, Dervisoglu A, Kesim M, Guven H and Polat C: Is pneumoperitoneum harmful during intra-abdominal hemorrhage in rats? J Laparoendosc Adv Surg Tech A. 15:112–120. 2005.PubMed/NCBI View Article : Google Scholar

5 

Demetriades D, Scalea TM, Degiannis E, Barmparas G, Konstantinidis A, Massahis J and Inaba K: Blunt splenic trauma: Splenectomy increases early infectious complications: A prospective multicenter study. J Trauma Acute Care Surg. 72:229–234. 2012.PubMed/NCBI View Article : Google Scholar

6 

Dobremez E, Lefevre Y, Harper L, Rebouissoux L, Lavrand F, Bondonny JM and Vergnes P: Complications occurring during conservative management of splenic trauma in children. Eur J Pediatr Surg. 16:166–170. 2006.PubMed/NCBI View Article : Google Scholar

7 

Hildebrand DR, Ben-sassi A, Ross NP, Macvicar R, Frizelle FA and Watson AJ: Modern management of splenic trauma. BMJ. 348(g1864)2014.PubMed/NCBI View Article : Google Scholar

8 

Coccolini F, Montori G, Catena F, Kluger Y, Biffl W, Moore EE, Reva V, Bing C, Bala M, Fugazzola P, et al: Splenic trauma: WSES classification and guidelines for adult and pediatric patients. World J Emerg Surg. 12(40)2017.PubMed/NCBI View Article : Google Scholar

9 

Moore EE, Shackford SR, Pachter HL, McAninch JW, Browner BD, Champion HR, Flint LM, Gennarelli TA, Malangoni MA and Ramenofsky ML: Organ injury scaling: Spleen, liver, and kidney. J Trauma. 29:1664–1666. 1989.PubMed/NCBI

10 

Meldrum DR, Moore FA, Moore EE, Franciose RJ, Sauaia A and Burch JM: Prospective characterization and selective management of the abdominal compartment syndrome. Am J Surg. 174:667–672; discussion 672-3. 1997.PubMed/NCBI View Article : Google Scholar

11 

Patlas MN: CT Imaging and management of blunt splenic trauma: Lessons for today and tomorrow. Radiology. 299:131–132. 2021.PubMed/NCBI View Article : Google Scholar

12 

Shi H, Teoh WC, Chin FWK, Tirukonda PS, Cheong SCW and Yiin RSZ: CT of blunt splenic injuries: What the trauma team wants to know from the radiologist. Clin Radiol. 74:903–911. 2019.PubMed/NCBI View Article : Google Scholar

13 

Adibi A, Ferasat F, Baradaran Mahdavi M, Kazemi K and Sadeghian S: Assessment of blunt splenic trauma: Which imaging scoring system is superior? J Res Med Sci. 23(29)2018.PubMed/NCBI View Article : Google Scholar

14 

Fodor M, Primavesi F, Morell-Hofert D, Kranebitter V, Palaver A, Braunwarth E, Haselbacher M, Nitsche U, Schmid S, Blauth M, et al: Non-operative management of blunt hepatic and splenic injury: A time-trend and outcome analysis over a period of 17 years. World J Emerg Surg. 14(29)2019.PubMed/NCBI View Article : Google Scholar

15 

Seshadri A, Brat GA, Yorkgitis BK, Keegan J, Dolan J, Salim A, Askari R and Lederer JA: Phenotyping the immune response to trauma: A Multiparametric Systems Immunology Approach. Crit Care Med. 45:1523–1530. 2017.PubMed/NCBI View Article : Google Scholar

16 

Hildebrand F, Pape HC and Krettek C: The importance of cytokines in the posttraumatic inflammatory reaction. Unfallchirurg. 108:793–794, 796-803. 2005.PubMed/NCBI View Article : Google Scholar : (In German).

17 

Jogia T, Lübstorf T, Jacobson E, Scriven E, Atresh S, Nguyen QH, Liebscher T, Schwab JM, Kopp MA, Walsham J, et al: Prognostic value of early leukocyte fluctuations for recovery from traumatic spinal cord injury. Clin Transl Med. 11(e272)2021.PubMed/NCBI View Article : Google Scholar

18 

Hazeldine J, Naumann DN, Toman E, Davies D, Bishop JRB, Su Z, Hampson P, Dinsdale RJ, Crombie N, Duggal NA, et al: Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study. PLoS Med. 14(e1002338)2017.PubMed/NCBI View Article : Google Scholar

19 

Timmermans K, Kox M, Vaneker M, van den Berg M, John A, van Laarhoven A, van der Hoeven H, Scheffer GJ and Pickkers P: Plasma levels of danger-associated molecular patterns are associated with immune suppression in trauma patients. Intensive Care Med. 42:551–561. 2016.PubMed/NCBI View Article : Google Scholar

20 

Billiar TR and Vodovotz Y: Time for trauma immunology. PLoS Med. 14(e1002342)2017.PubMed/NCBI View Article : Google Scholar

21 

Soulaiman SE, Dopa D, Raad AT, Hasan W, Ibrahim N, Hasan AY, Sulaiman HA and Darwich M: Cohort retrospective study: The neutrophil to lymphocyte ratio as an independent predictor of outcomes at the presentation of the multi-trauma patient. Int J Emerg Med. 13(5)2020.PubMed/NCBI View Article : Google Scholar

22 

Namas RA, Vodovotz Y, Almahmoud K, Abdul-Malak O, Zaaqoq A, Namas R, Mi Q, Barclay D, Zuckerbraun B, Peitzman AB, et al: Temporal patterns of circulating inflammation biomarker networks differentiate susceptibility to nosocomial infection following blunt trauma in humans. Ann Surg. 263:191–198. 2016.PubMed/NCBI View Article : Google Scholar

23 

Orr SK, Butler KL, Hayden D, Tompkins RG, Serhan CN and Irimia D: Gene expression of proresolving lipid mediator pathways is associated with clinical outcomes in trauma patients. Crit Care Med. 43:2642–2650. 2015.PubMed/NCBI View Article : Google Scholar

24 

Vanzant EL, Hilton RE, Lopez CM, Zhang J, Ungaro RF, Gentile LF, Szpila BE, Maier RV, Cuschieri J, Bihorac A, et al: Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock. Crit Care. 19(77)2015.PubMed/NCBI View Article : Google Scholar

25 

Cheron A, Floccard B, Allaouchiche B, Guignant C, Poitevin F, Malcus C, Crozon J, Faure A, Guillaume C, Marcotte G, et al: Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma. Crit Care. 14(R208)2010.PubMed/NCBI View Article : Google Scholar

26 

Furman BD, Mangiapani DS, Zeitler E, Bailey KN, Horne PH, Huebner JL, Kraus VB, Guilak F and Olson SA: Targeting pro-inflammatory cytokines following joint injury: Acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis. Arthritis Res Ther. 16(R134)2014.PubMed/NCBI View Article : Google Scholar

27 

Tursich M, Neufeld RW, Frewen PA, Harricharan S, Kibler JL, Rhind SG and Lanius RA: Association of trauma exposure with proinflammatory activity: A transdiagnostic meta-analysis. Transl Psychiatry. 4(e413)2014.PubMed/NCBI View Article : Google Scholar

28 

Skjelbred P and Løkken P: Anti-inflammatory agents in acute tissue trauma. Choice and effects. Tidsskr Nor Laegeforen. 113:439–443. 1993.PubMed/NCBI(In Norwegian).

29 

Fung KW, Xu J and Bodenreider O: The new International classification of diseases 11th edition: A comparative analysis with ICD-10 and ICD-10-CM. J Am Med Inform Assoc. 27:738–746. 2020.PubMed/NCBI View Article : Google Scholar

30 

Russu E, Mureșan AV, Arbănași EM, Kaller R, Hosu I, Voidăzan S, Arbănași EM and Coșarcă CM: The predictive role of NLR and PLR in outcome and patency of lower limb revascularization in patients with femoropopliteal disease. Clin Med. 11(2620)2022.PubMed/NCBI View Article : Google Scholar

31 

Baker SP, O'Neill B, Haddon W Jr and Long WB: The injury severity score: A method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 14:187–196. 1974.PubMed/NCBI

32 

El-Matbouly M, Jabbour G, El-Menyar A, Peralta R, Abdelrahman H, Zarour A, Al-Hassani A and Al-Thani H: Blunt splenic trauma: Assessment, management and outcomes. Surgeon. 14:52–58. 2016.PubMed/NCBI View Article : Google Scholar

33 

Richards JR and McGahan JP: Focused assessment with sonography in trauma (FAST) in 2017: What radiologists can learn. Radiology. 283:30–48. 2017.PubMed/NCBI View Article : Google Scholar

34 

Stengel D, Bauwens K, Sehouli J, Porzsolt F, Rademacher G, Mutze S and Ekkernkamp A: Systematic review and meta-analysis of emergency ultrasonography for blunt abdominal trauma. Br J Surg. 88:901–912. 2001.PubMed/NCBI View Article : Google Scholar

35 

Yoong S, Kothari R and Brooks A: Assessment of sensitivity of whole body CT for major trauma. Eur J Trauma Emerg Surg. 45:489–492. 2019.PubMed/NCBI View Article : Google Scholar

36 

Wang J, Wood A, Gao C, Najarian K and Gryak J: Automated spleen injury detection using 3D active contours and machine learning. Entropy (Basel). 23(382)2021.PubMed/NCBI View Article : Google Scholar

37 

Malaki M and Mangat K: Hepatic and splenic trauma. Trauma. 13:2011.

38 

Harna B, Arya S and Bahl A: Epidemiology of trauma patients admitted to a trauma center in New Delhi, India. Indian J Crit Care Med. 24:1193–1197. 2020.PubMed/NCBI View Article : Google Scholar

39 

Lenz A, Franklin GA and Cheadle WG: Systemic inflammation after trauma. Injury. 38:1336–1345. 2007.PubMed/NCBI View Article : Google Scholar

40 

Chia TL, Chesney TR, Isa D, Mnatzakanian G, Colak E, Belmont C, Hirpara D, Veigas PV, Acuna SA, Rizoli S and Rezende-Neto J: Thrombocytosis in splenic trauma: In-hospital course and association with venous thromboembolism. Injury. 48:142–147. 2017.PubMed/NCBI View Article : Google Scholar

41 

Salim A, Hadjizacharia P, DuBose J, Kobayashi L, Inaba K, Chan LS and Margulies DR: What is the significance of thrombocytosis in patients with trauma? J Trauma. 66:1349–1354. 2009.PubMed/NCBI View Article : Google Scholar

42 

Khan PN, Nair RJ, Olivares J, Tingle LE and Li Z: Postsplenectomy reactive thrombocytosis. Proc (Bayl Univ Med Cent). 22:9–12. 2009.PubMed/NCBI View Article : Google Scholar

43 

Arbănași EM, Mureșan AV, Coșarcă CM, Kaller R, Bud TI, Hosu I, Voidăzan ST, Arbănași EM and Russu E: Neutrophil-to-Lymphocyte ratio and platelet-to-lymphocyte ratio impact on predicting outcomes in patients with acute limb ischemia. Life (Basel). 12(822)2022.PubMed/NCBI View Article : Google Scholar

44 

Younan D, Richman J, Zaky A and Pittet JF: An increasing neutrophil-to-lymphocyte ratio trajectory predicts organ failure in critically-Ill male trauma patients. An exploratory study. Healthcare (Basel). 7(42)2019.PubMed/NCBI View Article : Google Scholar

45 

Dilektasli E, Inaba K, Haltmeier T, Wong MD, Clark D, Benjamin ER, Lam L and Demetriades D: The prognostic value of neutrophil-to-lymphocyte ratio on mortality in critically ill trauma patients. J Trauma Acute Care Surg. 81:882–888. 2016.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Vunvulea V, Suciu BA, Cocuz IG, Bacalbașa N, Molnar C, Ghiga DV and Hălmaciu I: Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience. Biomed Rep 17: 80, 2022.
APA
Vunvulea, V., Suciu, B.A., Cocuz, I.G., Bacalbașa, N., Molnar, C., Ghiga, D.V., & Hălmaciu, I. (2022). Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience. Biomedical Reports, 17, 80. https://doi.org/10.3892/br.2022.1563
MLA
Vunvulea, V., Suciu, B. A., Cocuz, I. G., Bacalbașa, N., Molnar, C., Ghiga, D. V., Hălmaciu, I."Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience". Biomedical Reports 17.4 (2022): 80.
Chicago
Vunvulea, V., Suciu, B. A., Cocuz, I. G., Bacalbașa, N., Molnar, C., Ghiga, D. V., Hălmaciu, I."Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience". Biomedical Reports 17, no. 4 (2022): 80. https://doi.org/10.3892/br.2022.1563
Copy and paste a formatted citation
x
Spandidos Publications style
Vunvulea V, Suciu BA, Cocuz IG, Bacalbașa N, Molnar C, Ghiga DV and Hălmaciu I: Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience. Biomed Rep 17: 80, 2022.
APA
Vunvulea, V., Suciu, B.A., Cocuz, I.G., Bacalbașa, N., Molnar, C., Ghiga, D.V., & Hălmaciu, I. (2022). Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience. Biomedical Reports, 17, 80. https://doi.org/10.3892/br.2022.1563
MLA
Vunvulea, V., Suciu, B. A., Cocuz, I. G., Bacalbașa, N., Molnar, C., Ghiga, D. V., Hălmaciu, I."Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience". Biomedical Reports 17.4 (2022): 80.
Chicago
Vunvulea, V., Suciu, B. A., Cocuz, I. G., Bacalbașa, N., Molnar, C., Ghiga, D. V., Hălmaciu, I."Importance of the neutrophil‑to‑lymphocyte ratio as a prognostic factor in patients with spleen trauma: A single center experience". Biomedical Reports 17, no. 4 (2022): 80. https://doi.org/10.3892/br.2022.1563
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