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Clinical characteristics among patients with COVID‑19: A single‑center retrospective study

  • Authors:
    • Anjum Farhana
    • Bilal Ahmad Tantry
    • Naveed Nazir Shah
    • Altaf Bandy
    • Mudasar Nabi
    • Syed Quibtiya Khursheed
    • Mir Shahnawaz
    • Hena Mustafa
  • View Affiliations / Copyright

    Affiliations: Department of Microbiology, Government Medical College, Srinagar, Jammu and Kashmir 190010, India, Department of Pulmonary Medicine, Chest Disease Hospital, Government Medical College, Drugjan, Srinagar, Jammu and Kashmir 190001, India, Department of Family and Community Medicine, College of Medicine, Jouf University, Sakaka, Al Jouf 70214, Kingdom of Saudi Arabia, Department of Biochemistry, University of Kashmir, Srinagar, Jammu and Kashmir 190010, India, Department of Surgery, SKIMS Medical College, Srinagar, Jammu and Kashmir 191101, India, Department of Respiratory Medicine, Chest Disease Hospital, Government Medical College, Drugjan, Srinagar, Jammu and Kashmir 190010, India
    Copyright: © Farhana et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 94
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    Published online on: October 14, 2022
       https://doi.org/10.3892/br.2022.1577
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Abstract

The aim of the present study was to investigate the clinical features and laboratory parameters of hospitalized patients with coronavirus disease 2019 (COVID‑19) and assess the characteristics between severe and non‑severe cases. The study retrospectively analyzed the clinical data of 1,096 patients, of which, 626 (57.11%) and 470 (42.89%) were categorized into severe and non‑severe groups, respectively. Clinical parameters such as signs and symptoms, comorbidities, levels of D‑dimer, C‑reactive protein (CRP), interleukin 6 (IL‑6) and lactate dehydrogenase were analyzed. The data are presented as frequencies, means and standard deviations. The chi‑square test and Mann‑Whitney U test were used to assess any significant differences between the severe and non‑severe COVID‑19 groups. The clinical symptoms in severe COVID‑19 cases included anosmia (P≤0.01), sore throat (P≤0.01), fatigue (P≤0.01), headache (P≤0.01), and shortness of breath (P≤0.01). Laboratory findings showed a significant increase in CRP (21.90±40.23 vs. 16.13±21.82; P≤0.01) and IL‑6 levels (58.92±55.07 vs. 41.41±38.30; P≤0.01). Patients with severe COVID‑19 had significant lymphopenia compared with that in non‑severe cases. Among the comorbidities, hypertension (P≤0.01) was significantly more frequent in patients with severe COVID‑19. In conclusion, major derangements in laboratory parameters were observed in patients with severe COVID‑19 infection.
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Copy and paste a formatted citation
Spandidos Publications style
Farhana A, Tantry BA, Shah NN, Bandy A, Nabi M, Khursheed SQ, Shahnawaz M and Mustafa H: Clinical characteristics among patients with COVID‑19: A single‑center retrospective study. Biomed Rep 17: 94, 2022.
APA
Farhana, A., Tantry, B.A., Shah, N.N., Bandy, A., Nabi, M., Khursheed, S.Q. ... Mustafa, H. (2022). Clinical characteristics among patients with COVID‑19: A single‑center retrospective study. Biomedical Reports, 17, 94. https://doi.org/10.3892/br.2022.1577
MLA
Farhana, A., Tantry, B. A., Shah, N. N., Bandy, A., Nabi, M., Khursheed, S. Q., Shahnawaz, M., Mustafa, H."Clinical characteristics among patients with COVID‑19: A single‑center retrospective study". Biomedical Reports 17.6 (2022): 94.
Chicago
Farhana, A., Tantry, B. A., Shah, N. N., Bandy, A., Nabi, M., Khursheed, S. Q., Shahnawaz, M., Mustafa, H."Clinical characteristics among patients with COVID‑19: A single‑center retrospective study". Biomedical Reports 17, no. 6 (2022): 94. https://doi.org/10.3892/br.2022.1577
Copy and paste a formatted citation
x
Spandidos Publications style
Farhana A, Tantry BA, Shah NN, Bandy A, Nabi M, Khursheed SQ, Shahnawaz M and Mustafa H: Clinical characteristics among patients with COVID‑19: A single‑center retrospective study. Biomed Rep 17: 94, 2022.
APA
Farhana, A., Tantry, B.A., Shah, N.N., Bandy, A., Nabi, M., Khursheed, S.Q. ... Mustafa, H. (2022). Clinical characteristics among patients with COVID‑19: A single‑center retrospective study. Biomedical Reports, 17, 94. https://doi.org/10.3892/br.2022.1577
MLA
Farhana, A., Tantry, B. A., Shah, N. N., Bandy, A., Nabi, M., Khursheed, S. Q., Shahnawaz, M., Mustafa, H."Clinical characteristics among patients with COVID‑19: A single‑center retrospective study". Biomedical Reports 17.6 (2022): 94.
Chicago
Farhana, A., Tantry, B. A., Shah, N. N., Bandy, A., Nabi, M., Khursheed, S. Q., Shahnawaz, M., Mustafa, H."Clinical characteristics among patients with COVID‑19: A single‑center retrospective study". Biomedical Reports 17, no. 6 (2022): 94. https://doi.org/10.3892/br.2022.1577
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