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Review Open Access

Exploring the optimal vaccination strategy against hepatitis B virus in childhood (Review)

  • Authors:
    • Anna Kramvis
    • Ioannis N. Mammas
    • Demetrios A. Spandidos
  • View Affiliations / Copyright

    Affiliations: Hepatitis Virus Diversity Research Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of The Witwatersrand, Johannesburg 2193, South Africa, Paediatric Clinic, Aliveri, 34500 Island of Euboea, Greece, Department of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece
    Copyright: © Kramvis et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 48
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    Published online on: June 9, 2023
       https://doi.org/10.3892/br.2023.1631
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Abstract

Vaccination against hepatitis B virus (HBV) remains the most effective strategy against HBV infection in humans. The present review summarized the optimal vaccination strategies against HBV in childhood. The following points are discussed: i) When and how the first HBV vaccines were developed; ii) the dosages, schedules and injection routes that are used for HBV vaccination; iii) the contraindications for HBV vaccination in the general paediatric population; iv) the challenges with the use of multivalent vaccines; v) the long‑term immunogenicity and duration of protection against HBV; vi) the use of selective HBV vaccination and the hepatitis B immune globulin strategy in HBV‑exposed infants; and vii) the effectiveness of the current HBV vaccination schemes. The present review is based on a Paediatric Virology Study Group (PVSG) webinar performed in the context of the 8th Workshop on Paediatric Virology.
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Copy and paste a formatted citation
Spandidos Publications style
Kramvis A, Mammas IN and Spandidos DA: Exploring the optimal vaccination strategy against hepatitis B virus in childhood (Review). Biomed Rep 19: 48, 2023.
APA
Kramvis, A., Mammas, I.N., & Spandidos, D.A. (2023). Exploring the optimal vaccination strategy against hepatitis B virus in childhood (Review). Biomedical Reports, 19, 48. https://doi.org/10.3892/br.2023.1631
MLA
Kramvis, A., Mammas, I. N., Spandidos, D. A."Exploring the optimal vaccination strategy against hepatitis B virus in childhood (Review)". Biomedical Reports 19.1 (2023): 48.
Chicago
Kramvis, A., Mammas, I. N., Spandidos, D. A."Exploring the optimal vaccination strategy against hepatitis B virus in childhood (Review)". Biomedical Reports 19, no. 1 (2023): 48. https://doi.org/10.3892/br.2023.1631
Copy and paste a formatted citation
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Spandidos Publications style
Kramvis A, Mammas IN and Spandidos DA: Exploring the optimal vaccination strategy against hepatitis B virus in childhood (Review). Biomed Rep 19: 48, 2023.
APA
Kramvis, A., Mammas, I.N., & Spandidos, D.A. (2023). Exploring the optimal vaccination strategy against hepatitis B virus in childhood (Review). Biomedical Reports, 19, 48. https://doi.org/10.3892/br.2023.1631
MLA
Kramvis, A., Mammas, I. N., Spandidos, D. A."Exploring the optimal vaccination strategy against hepatitis B virus in childhood (Review)". Biomedical Reports 19.1 (2023): 48.
Chicago
Kramvis, A., Mammas, I. N., Spandidos, D. A."Exploring the optimal vaccination strategy against hepatitis B virus in childhood (Review)". Biomedical Reports 19, no. 1 (2023): 48. https://doi.org/10.3892/br.2023.1631
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