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Review Open Access

Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review)

  • Authors:
    • Cut Raihanah
    • Sukrasno Sukrasno
    • Neng Fisheri Kurniati
  • View Affiliations / Copyright

    Affiliations: Department of Pharmaceutical Biology, School of Pharmacy, Bandung Institute of Technology, Bandung 40132, Indonesia, Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Bandung Institute of Technology, Bandung 40132, Indonesia
    Copyright: © Raihanah et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 80
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    Published online on: March 21, 2024
       https://doi.org/10.3892/br.2024.1768
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Abstract

Polycystic ovary syndrome (PCOS), a hormonal and metabolic disorder manifested in women of reproductive age, is still being treated using drugs with side effects. As an alternative to these drugs, isoflavone, also identified as phytoestrogen, has anti‑PCOS activity. Isoflavone can help relieve PCOS symptoms by lowering the level of testosterone, which causes hyperandrogenism, thereby normalizing the menstrual cycle and restoring normal ovarian morphology. Furthermore, isoflavone influences the improvement of the metabolic profile, which changes because of PCOS, as well as the reduction of inflammatory markers and oxidative stress. However, both significant and non‑significant results have been generated on the activity of isoflavones in PCOS. The present review aims to discuss the existing literature on the effect of isoflavone on PCOS symptoms based on in vivo and clinical trial studies.
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Copy and paste a formatted citation
Spandidos Publications style
Raihanah C, Sukrasno S and Kurniati N: Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review). Biomed Rep 20: 80, 2024.
APA
Raihanah, C., Sukrasno, S., & Kurniati, N. (2024). Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review). Biomedical Reports, 20, 80. https://doi.org/10.3892/br.2024.1768
MLA
Raihanah, C., Sukrasno, S., Kurniati, N."Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review)". Biomedical Reports 20.5 (2024): 80.
Chicago
Raihanah, C., Sukrasno, S., Kurniati, N."Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review)". Biomedical Reports 20, no. 5 (2024): 80. https://doi.org/10.3892/br.2024.1768
Copy and paste a formatted citation
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Spandidos Publications style
Raihanah C, Sukrasno S and Kurniati N: Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review). Biomed Rep 20: 80, 2024.
APA
Raihanah, C., Sukrasno, S., & Kurniati, N. (2024). Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review). Biomedical Reports, 20, 80. https://doi.org/10.3892/br.2024.1768
MLA
Raihanah, C., Sukrasno, S., Kurniati, N."Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review)". Biomedical Reports 20.5 (2024): 80.
Chicago
Raihanah, C., Sukrasno, S., Kurniati, N."Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review)". Biomedical Reports 20, no. 5 (2024): 80. https://doi.org/10.3892/br.2024.1768
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