Intrahepatic portal vein aneurysm: A case report

Wang,Yinjiao; Cao,Aihong; Du,Peng

doi:10.3892/br.2025.1985

Intrahepatic portal vein aneurysm: A case report

Authors:
- Yinjiao Wang
- Aihong Cao
- Peng Du
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Affiliations: Department of Radiology, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221000, P.R. China
Published online on: April 28, 2025 https://doi.org/10.3892/br.2025.1985
Article Number: 107
Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Portal vein aneurysm (PVA), a rare vascular anomaly characterized by localized dilation of the portal venous system, demonstrates distinct pathological features, including progressive wall thinning with marked attenuation of both intimal and medial layers. Current classification systems categorize PVAs based on anatomical location. Intrahepatic variants involve portal vein branches within the hepatic parenchyma, while extrahepatic types predominantly affect the main portal trunk extending from the splenomesenteric confluence to the hepatic hilum, with the extrahepatic type being the most common. The current study presents a case of PVA, demonstrating the synergistic diagnostic value of abdominal ultrasonography and multiphase contrast‑enhanced CT in vascular malformation management. Multimodal imaging characterization not only precisely delineated the three‑dimensional anatomical heterogeneity of the lesion but also dynamically demonstrated the spatiotemporal hemodynamic evolution of the portal venous system, providing crucial imaging‑based evidence for clinical decision‑making in individualized treatment planning for patients with PVA.

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1	Barzilai R and Kleckner MS Jr: Hemocholecyst following ruptured aneurysm of portal vein; report of a case. AMA Arch Surg. 72:725–727. 1956.PubMed/NCBI View Article : Google Scholar
2	Laurenzi A, Ettorre GM, Lionetti R, Meniconi RL, Colasanti M and Vennarecci G: Portal vein aneurysm: What to know. Dig Liver Dis. 47:918–923. 2015.PubMed/NCBI View Article : Google Scholar
3	López-Sánchez J, Santabrígida Oreja G, Quiñones Sampedro JE and Muñoz-Bellvís L: Portal vein aneurysm associated with extensive portal-mesenteric thrombosis. Cir Esp (Engl Ed). 101(863)2023.PubMed/NCBI View Article : Google Scholar
4	Vine HS, Sequeira JC, Widrich WC and Sacks BA: Portal vein aneurysm. AJR Am J Roentgenol. 132:557–560. 1979.PubMed/NCBI View Article : Google Scholar
5	Chaubard S, Lacroix P, Kennel C and Jaccard A: Aneurysm of the portal venous system: A rare and unknown pathology. Rev Med Interne. 39:946–949. 2018.PubMed/NCBI View Article : Google Scholar : (In French).
6	Kurtcehajic A, Vele E and Hujdurovic A: Portal vein aneurysm and portal biliopathy. J Hepatobiliary Pancreat Sci. 23(658)2016.PubMed/NCBI View Article : Google Scholar
7	Levi Sandri GB, Sulpice L, Rayar M, Bosquet E, Boudjema K and Meunier B: Extrahepatic portal vein aneurysm. Ann Vasc Surg. 28:1319.e5–7. 2014.PubMed/NCBI View Article : Google Scholar
8	De Vloo C, Matton T, Meersseman W, Maleux G, Houthoofd S, Op de Beeck K, Laleman W, Van Malenstein H, Nevens F, Verbeke L, et al: Thrombosis of a portal vein aneurysm: A case report with literature review. Acta Clin Belg. 74:115–120. 2019.PubMed/NCBI View Article : Google Scholar
9	Ohnami Y, Ishida H, Konno K, Naganuma H, Hamashima Y, Zeniya A and Masamune O: Portal vein aneurysm: report of six cases and review of the literature. Abdom Imaging. 22:281–286. 1997.PubMed/NCBI View Article : Google Scholar
10	Binko MA, Andraska EA, Reitz KM, Handzel RM, Singh MJ, Sridharan ND, Chaer RA and Hager ES: The natural history of portal venous system aneurysms. J Vasc Surg Venous Lymphat Disord. 13(102163)2025.PubMed/NCBI View Article : Google Scholar
11	Andraus W, Amico EC, Machado MA, Bacchella T and Machado MC: Portal vein aneurysm. Clinics (Sao Paulo). 62:203–205. 2007.PubMed/NCBI View Article : Google Scholar
12	Tanaka H, Muromachi K, Tamai T, Hashiguchi M, Enokizono R, Nakajyo Y, Iryo Y, Hori T, Tsubouchi H and Ido A: Extrahepatic portal vein aneurysm in which the acute thrombogenic process triggered by trauma confirmed by abdominal ultrasonography: A case report. Clin J Gastroenterol. 16:702–708. 2023.PubMed/NCBI View Article : Google Scholar
13	Moreno JA, Fleming MD, Farnell MB and Gloviczki P: Extrahepatic portal vein aneurysm. J Vasc Surg. 54:225–226. 2011.PubMed/NCBI View Article : Google Scholar
14	Yedlicka GM, Maatman TK, Mangus RS and Nakeeb A: Operative treatment of portal vein aneurysm. Surg Open Sci. 10:165–167. 2022.PubMed/NCBI View Article : Google Scholar
15	Amato ACM, da Silva AEC, Bernal IM, de Oliveira JC, Di Paschoal Almeida Ribeiro M, Schinzari PS and Dos Santos RV: Combined nutcracker and ehlers-danlos syndromes: A case report. EJVES Vasc Forum. 47:12–17. 2020.PubMed/NCBI View Article : Google Scholar
16	Moretti G, Staeffen J, Broustet A and Le Bras M: Congenital malformations associated with stenosis of the portal vein. Sem Hop. 44:893–897. 1968.PubMed/NCBI(In French).
17	Passi N, Wadhwa AC and Naik S: Radiological evaluation of extrahepatic and intrahepatic portal vein aneurysms: A report of two cases. Radiol Case Rep. 17:4784–4789. 2022.PubMed/NCBI View Article : Google Scholar
18	Hirji SA, Robertson FC, Casillas S, McPhee JT, Gupta N, Martin MC and Raffetto JD: Asymptomatic portal vein aneurysms: To treat, or not to treat? Phlebology. 33:513–516. 2018.PubMed/NCBI View Article : Google Scholar
19	Koc Z, Oguzkurt L and Ulusan S: Portal venous system aneurysms: Imaging, clinical findings, and a possible new etiologic factor. AJR Am J Roentgenol. 189:1023–1030. 2007.PubMed/NCBI View Article : Google Scholar
20	Murty T and Negrete L: Portal venous aneurysm. Radiology. 307(e221311)2023.PubMed/NCBI View Article : Google Scholar
21	Tan RLW and Ng ZQ: Portal venous aneurysm. BMJ Case Rep. 14(e244704)2021.PubMed/NCBI View Article : Google Scholar
22	Nangou P, Bertrand P, Samann I, Filali A, el Hassani R, Benabdellah C, Elhadj R, Boulakia C and Icard P: Portal vein aneurysm. Ann Chir. 125:476–478. 2000.PubMed/NCBI View Article : Google Scholar : (In French).
23	Qi X, Yin Z, He C, Guo W, Han G and Fan D: Extrahepatic portal vein aneurysm. Clin Res Hepatol Gastroenterol. 37:1–2. 2013.PubMed/NCBI View Article : Google Scholar
24	Haddad A, Fraiman M and Mackey R: Portal vein aneurysm. Am Surg. 77:503–505. 2011.PubMed/NCBI
25	Cho SW, Marsh JW, Fontes PA, Daily MF, Nalesnik M, Tublin M, De Vera ME, Geller DA and Gamblin TC: Extrahepatic portal vein aneurysm-report of six patients and review of the literature. J Gastrointest Surg. 12:145–152. 2008.PubMed/NCBI View Article : Google Scholar
26	Kurtcehajic A, Zerem E, Alibegovic E, Kunosic S, Hujdurovic A and Fejzic JA: Portal vein aneurysm-etiology, multimodal imaging and current management. World J Clin Cases. 11:725–737. 2023.PubMed/NCBI View Article : Google Scholar
27	Ma R, Balakrishnan A, See TC, Liau SS, Praseedom R and Jah A: Extra-hepatic portal vein aneurysm: A case report, overview of the literature and suggested management algorithm. Int J Surg Case Rep. 3:555–558. 2012.PubMed/NCBI View Article : Google Scholar
28	Liu Y, Arief J, Xiu W, Hao X, Wang F, Xia N and Dong Q: Case Report: Management of a congenital intrahepatic portosystemic shunt with portal vein aneurysm in a child using 3D computer-assisted partial right hepatectomy. Front Pediatr. 12(1429537)2024.PubMed/NCBI View Article : Google Scholar
29	Kim HU, Mateja HL, Neris R, Kimyaghalam A and DeVito PM: Asymptomatic portal vein aneurysm uncovered during the evaluation of a gastrointestinal hemorrhage: A rare clinical case. Cureus. 16(e68388)2024.PubMed/NCBI View Article : Google Scholar
30	Lenaerts YF, Labarque V and Limantoro I: Thrombosed massive portal vein aneurysm in an adolescent boy. Pediatr Radiol. 54:1928–1932. 2024.PubMed/NCBI View Article : Google Scholar
31	Higashi S, Nakabori T, Mukai K, Seiki Y, Watsuji K, Hirao T, Kawamoto Y, Urabe M, Kai Y, Takada R, et al: Portal vein aneurysm in a patient with cirrhosis type C controlled by direct-acting antiviral treatment. Case Rep Gastroenterol. 18:74–80. 2024.PubMed/NCBI View Article : Google Scholar
32	Monville JF, Meurisse N and Dondelinger RF: Anticoagulant Treatment of a Thrombosed Giant Portal Vein Aneurysm. J Belg Soc Radiol. 108(8)2024.PubMed/NCBI View Article : Google Scholar