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Article

Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging

  • Authors:
    • Tomoyoshi Aoyagi
    • Kiyohiko Shuto
    • Shinichi Okazumi
    • Hideaki Shimada
    • Yoshihiro Nabeya
    • Toshiki Kazama
    • Hisahiro Matsubara
  • View Affiliations / Copyright

    Affiliations: Department of Frontier Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan, Department of Radiology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan
  • Pages: 847-851
    |
    Published online on: July 12, 2010
       https://doi.org/10.3892/etm.2010.112
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Abstract

The purpose of this study was to assess the effectiveness of the apparent diffusion coefficient (ADC) using diffusion-weighted imaging (DWI) for the clinical staging of esophageal cancer. The ADC of the tumors was compared to the standardized uptake value (SUV) of 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET). A total of 123 consecutive patients with esophageal squamous cell cancer were enrolled. DW images were obtained using a 1.5T whole-body scanner equipped with a phased-array body coil. A single shot spin-echo type of echo-planar sequence that provided diffusion weighting in the direction of the slice selection was used to obtain DW images. There was a negative correlation between the ADC value of the tumors and tumor diameter. A negative correlation was also found between the ADC value/SUV of the FDG-PET and serum levels of the tumor markers squamous cell carcinoma antigen and CYFRA. The ADC value was significantly correlated with clinical T and N stages. The ADC values of advanced-stage tumors were significantly lower than those of early-stage tumors. The ADC value of esophageal cancer decreased as the clinical stage advanced, and was correlated with the clinical findings. This non-invasive modality may be a valid clinical imaging method for the staging of esophageal cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Aoyagi T, Shuto K, Okazumi S, Shimada H, Nabeya Y, Kazama T and Matsubara H: Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging. Exp Ther Med 1: 847-851, 2010.
APA
Aoyagi, T., Shuto, K., Okazumi, S., Shimada, H., Nabeya, Y., Kazama, T., & Matsubara, H. (2010). Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging. Experimental and Therapeutic Medicine, 1, 847-851. https://doi.org/10.3892/etm.2010.112
MLA
Aoyagi, T., Shuto, K., Okazumi, S., Shimada, H., Nabeya, Y., Kazama, T., Matsubara, H."Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging". Experimental and Therapeutic Medicine 1.5 (2010): 847-851.
Chicago
Aoyagi, T., Shuto, K., Okazumi, S., Shimada, H., Nabeya, Y., Kazama, T., Matsubara, H."Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging". Experimental and Therapeutic Medicine 1, no. 5 (2010): 847-851. https://doi.org/10.3892/etm.2010.112
Copy and paste a formatted citation
x
Spandidos Publications style
Aoyagi T, Shuto K, Okazumi S, Shimada H, Nabeya Y, Kazama T and Matsubara H: Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging. Exp Ther Med 1: 847-851, 2010.
APA
Aoyagi, T., Shuto, K., Okazumi, S., Shimada, H., Nabeya, Y., Kazama, T., & Matsubara, H. (2010). Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging. Experimental and Therapeutic Medicine, 1, 847-851. https://doi.org/10.3892/etm.2010.112
MLA
Aoyagi, T., Shuto, K., Okazumi, S., Shimada, H., Nabeya, Y., Kazama, T., Matsubara, H."Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging". Experimental and Therapeutic Medicine 1.5 (2010): 847-851.
Chicago
Aoyagi, T., Shuto, K., Okazumi, S., Shimada, H., Nabeya, Y., Kazama, T., Matsubara, H."Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging". Experimental and Therapeutic Medicine 1, no. 5 (2010): 847-851. https://doi.org/10.3892/etm.2010.112
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