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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-October 2010 Volume 1 Issue 5

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Impact Factor: 2.3

Review

Gas plasma sterilization of microorganisms and mechanisms of action (Review)

Hideharu Shintani, Akikazu Sakudo, Peter Burke, Gerald McDonnell
Pages: 731-738
Published online on: 21 July 2010

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Article Open Access

Inhibition of tumor angiogenesis by oral etoposide

Dipak Panigrahy, Arja Kaipainen, Catherine E. Butterfield, Deviney M. Chaponis, Andrea M. Laforme, Judah Folkman, Mark W. Kieran
Pages: 739-746
Published online on: 21 July 2010

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Article Open Access

Ki-67 as a prognostic marker according to breast cancer subtype and a predictor of recurrence time in primary breast cancer

Reiki Nishimura, Tomofumi Osako, Yasuhiro Okumura, Mitsuhiro  Hayashi, Yasuo Toyozumi, Nobuyuki Arima
Pages: 747-754
Published online on: 21 July 2010

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Article

Osteoclast-related cytokines from biopsy specimens predict mandibular invasion by oral squamous cell carcinoma

Nianhui Cui, Takeshi Nomura, Nobuo Takano, Enbo Wang, Wei Zhang, Takeshi Onda, Takahiko Shibahara
Pages: 755-760
Published online on: 21 July 2010

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Article

Diesel exhaust particles induce a Th2 phenotype in mouse naïve mononuclear cells in vitro

Ken-ichiro Inoue, Eiko Koike, Akiko Endoh, Daigo Sumi, Yoshito Kumagai, Kazuichi Hayakawa, Masako Kiyono, Michitaka Tanaka, Hirohisa Takano
Pages: 761-767
Published online on: 21 July 2010

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Article

Non-surgical therapy and radiologic assessment of stage I breast cancer treatment with novel enzyme-targeting radiosensitization: Kochi Oxydol-Radiation Therapy for Unresectable Carcinomas, type II (KORTUC II)

Jiro Hitomi, Kei Kubota, Yasuhiro Ogawa, Norihiko Hamada, Yoriko Murata, Akihito Nishioka
Pages: 769-775
Published online on: 20 July 2010

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Article

Effectiveness of oral iron to manage anemia in long-term hemodialysis patients with the use of ultrapure dialysate

Akiyasu Tsuchida, Bishnuhari Paudyal, Pramila Paudyal, Yoshitaka Ishii, Keiju Hiromura, Yoshihisa Nojima, Minoru Komai
Pages: 777-781
Published online on: 20 July 2010

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Article

Prognostic significance of the mitochondrial scoring system in ovarian cancer

Ryuma Matsumoto, Seiji Isonishi, Kazuhiko Ochiai, Tomomi Hamada, Takako Kiyokawa, Toshiaki Tachibana, Hiroshi Ishikawa
Pages: 783-788
Published online on: 20 July 2010

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Article

Claudin-4 expression is associated with tumor invasion, MMP-2 and MMP-9 expression in gastric cancer

Tsann-Long Hwang, Li-Yu Lee, Chee-Chan Wang, Ying Liang, Shu-Fang Huang, Chi-Ming Wu
Pages: 789-797
Published online on: 12 July 2010

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Article

Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in surgically resectable stage III non-small cell lung cancer

Kyoichi Kaira, Noboru Oriuchi, Hisao Imai, Kimihiro Shimizu, Noriko Yanagitani, Noriaki Sunaga, Takeshi Hisada, Osamu Kawashima, Yosuke Kamide, Tamotsu Ishizuka, Yoshikatsu Kanai, Takashi Nakajima, Masatomo Mori
Pages: 799-808
Published online on: 20 July 2010

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Article

Characteristic expression pattern of oxidative stress in livers with cryptogenic hepatocellular carcinoma

Nobuyoshi Fukushima, Ryoko Kuromatsu, Jun Akiba, Eiji Ando, Akio Takata, Shuji Sumie, Masahito Nakano, Toru Nakamura, Akihiko Kawahara, Takuji Torimura, Osamu Nakashima, Koji Okuda, Hirohisa Yano, Masayoshi Kage, Masamichi Kojiro, Michio Sata
Pages: 809-816
Published online on: 21 July 2010

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Article

Evaluation of the effects of a supplementary diet containing chicken comb extract on symptoms and cartilage metabolism in patients with knee osteoarthritis

Isao Nagaoka, Kunihiro Nabeshima, Saya Murakami, Tetsuro Yamamoto, Keita Watanabe, Akihito Tomonaga, Hideyo Yamaguchi
Pages: 817-827
Published online on: 12 July 2010

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Article Open Access

FDG positron emission tomography/computed tomography findings for the prediction of early recurrence of hepatocellular carcinoma after surgical resection

Atsushi Hiraoka, Hironori Ochi, Satoshi Hidaka, Takahide Uehara, Aki Hasebe, Tetsuya Tanihira, Yasunao Miyamoto, Tomoyuki Ninomiya, Hideki Kawasaki, Ichiro Sogabe, Yoshihiro Ishimaru, Masao Miyagawa, Keizo Furuya, Masashi Hirooka, Masanori Abe, Yoichi Hiasa, Bunzo Matsuura, Morikazu Onji, Kojiro Michitaka
Pages: 829-832
Published online on: 21 July 2010

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Article

A β-tubulin 5-derived peptide induces cytotoxic T lymphocytes restricted to the HLA-A24 allele in prostate cancer patients

Nobukazu Komatsu, Yasunobu Terasaki, Fukuko Moriya, Shigetaka Suekane, Masanori Noguchi, Satoru Todo, Kyogo Itoh, Shigeki Shichijo
Pages: 833-839
Published online on: 20 July 2010

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Article

Decreased expression of FBXW7 is correlated with poor prognosis in patients with esophageal squamous cell carcinoma

Yasuhiro Naganawa, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Takeyasu Katada, Tatsuya Tanaka, Midori Shiozaki, Yoshitaka Fujii, Hiromitsu Takeyama
Pages: 841-846
Published online on: 12 July 2010

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Article

Evaluation of the clinical staging of esophageal cancer by using diffusion-weighted imaging

Tomoyoshi Aoyagi, Kiyohiko Shuto, Shinichi Okazumi, Hideaki Shimada, Yoshihiro Nabeya, Toshiki Kazama, Hisahiro Matsubara
Pages: 847-851
Published online on: 12 July 2010

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Article

Gemcitabine and paclitaxel suppress the production of vascular endothelial growth factor induced by deferoxamine in human non-small cell lung cancer A549 cells

Ryuji Ikeda, Lee C. Vermeulen, Zhisheng Jiang, Elim Lau, Jill M. Kolesar
Pages: 853-857
Published online on: 21 July 2010

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Article

Effects of carboxymethyl-glucan from Saccharomyces cerevisiae on the peripheral blood cells of patients with advanced prostate cancer

Marciane Magnani, Raul Hernan Castro-Gomez, Mateus Nobrega Aoki, Emerson Pereira Gregório, Farid Libos, Maria Angelica Ehara Watanabe
Pages: 859-862
Published online on: 20 July 2010

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Article

Sorafenib suppresses the cell cycle and induces the apoptosis of hepatocellular carcinoma cell lines in serum-free media

Minoru Tomizawa, Fuminobu Shinozaki, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi, Takanobu Yoshida
Pages: 863-866
Published online on: 21 July 2010

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Article

High-risk early breast cancer in patients under 40 years of age: Improved clinical outcome with total estrogen blockade and tailored chemotherapy

Francesco Recchia, Giampiero Candeloro, Stefania Discepoli, Marisa Grimaldi, Giovambattista Desideri, Stefano Necozione, Silvio Rea
Pages: 867-872
Published online on: 21 July 2010

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Article

Concentrations of IL-15, IL-18, IFN-γ and activity of CD4+, CD8+ and NK cells at admission in children with viral bronchiolitis

Elżbieta Grześk, Sylwia Kołtan, Robert Dębski, Mariusz  Wysocki, Marzena  Gruszka, Małgorzata  Kubicka, Andrzej  Kołtan, Grzegorz  Grześk, Sławomir Manysiak, Grażyna Odrowąż-Sypniewska
Pages: 873-877
Published online on: 20 July 2010

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Article

APC Yin-Yang haplotype associated with colorectal cancer risk

P. Garre, M. de la Hoya, P. Iniesta, A. Romera, P. Llovet, S. Gonzalez, P. Perez-Segura, G. Capella, E. Diaz-Rubio, T. Caldes
Pages: 879-883
Published online on: 21 July 2010

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Article

Relation between proinflammatory mediators and epithelial-mesenchymal transition in head and neck squamous cell carcinoma

Geun-Woo Dong, Nam-Yong Do, Sung-Chul Lim
Pages: 885-891
Published online on: 21 July 2010

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Article

High Dickkopf-1 expression is associated with poor prognosis in patients with advanced urothelial carcinoma

Cheng-Huang Shen, Hsiao-Yen Hsieh, Yuan-Hung Wang, Syue-Yi Chen, Chun-Liang Tung, Jiann-Der Wu, Chang-Te Lin, Michael W.-Y. Chan, Cheng-Da Hsu, Deching Chang
Pages: 893-898
Published online on: 21 July 2010

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Article

siRNA-mediated knockdown of VEGF-A, VEGF-C and VEGFR-3 suppresses the growth and metastasis of mouse bladder carcinoma in vivo

Feng Wang, Hui-Ming Li, Hui-Ping Wang, Jia-Lie Ma, Xia-Fang Chen, Fang Wei, Miao-Ying Yi, Qian Huang
Pages: 899-904
Published online on: 12 July 2010

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Article

Analysis of differential gene expression by bead-based fiber‑optic array in growth-hormone-secreting pituitary adenomas

Zhiquan Jiang, Songbo Gui, Yazhuo Zhang
Pages: 905-910
Published online on: 21 July 2010

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Journal Cover
May-2026 Volume 31 Issue 5

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Impact Factor: 2.3

Review Open Access

FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
Published online on: 26 March 2026

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Article Open Access

A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
Article Number: 145
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Article

Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Article Open Access

Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
Article Number: 142
Published online on: 19 March 2026

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Article Open Access

Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
Article Number: 141
Published online on: 19 March 2026

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Review Open Access

Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
Published online on: 19 March 2026

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Review Open Access

Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Article Open Access

Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
Published online on: 19 March 2026

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Review Open Access

Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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Retraction Open Access

[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Article Open Access

Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
Article Number: 135
Published online on: 13 March 2026

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Article Open Access

Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Article

Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Article Open Access

Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Article Open Access

Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Article

Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Case Report Open Access

Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Article

Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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Article Open Access

RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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Article Open Access

A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Impact Factor: 2.3

Article Open Access

Effects of rok1 gene deletion on mitosis in fission yeast at appropriate and stressful temperatures and the molecular mechanisms

Jiayi He, Mengnan Liu, Jiani Xu, Xiang Ding, Yiling Hou
Article Number: 151
Published online on: 02 April 2026

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Review Open Access

Therapeutic potential of allicin against viral infections: Mechanisms and safety profile (Review)

Ming-Jun Yu, Yong Zhu, Wei Zhang, Qiao-Ping Xu, Hai-Ming Wang, Zhao Ma
Article Number: 150
Published online on: 02 April 2026

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Interacting proteins of AMPK studied using TurboID proximity labeling technology

Xiaoshan Liu, Jieyu Guo, Qiongyao Wang, Wu Liu, Yan Xue, Shuang Guo, Miao Li
Article Number: 149
Published online on: 02 April 2026

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Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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