1.
|
Fearon ER and Volgestein B: A genetic
model for colorectal tumorigenesis. Cell. 61:759–767. 1990.
View Article : Google Scholar : PubMed/NCBI
|
2.
|
De la Chapelle A: Genetic predisposition
to colorectal cancer. Nat Rev Cancer. 4:769–779. 2004.
|
3.
|
Carlson CS, Eberle MA, Rieder MJ, Yi Q,
Kruglyak L and Nickerson DA: Selecting a maximally informative set
of single nucleotide polymorphisms for association analyses using
linkage disequilibrium. Am J Hum Genet. 74:106–120. 2004.
View Article : Google Scholar
|
4.
|
Gabriel SB, Scaffner SF, Nguyen H, et al:
The structure of haplotypes blocks in the human genome. Science.
296:2225–2229. 2002. View Article : Google Scholar : PubMed/NCBI
|
5.
|
The International HapMap Consortium: A
haplotype map of the human genome. Nature. 437:1299–1320. 2005.
View Article : Google Scholar
|
6.
|
Zhang J, Rowe WL, Clark AG and Buetow KH:
Genomewide distribution of high-frequency, completely mismatching
SNP haplotype pairs observed to be common across human populations.
Am J Hum Genet. 73:1073–1081. 2003. View
Article : Google Scholar
|
7.
|
Bodmer WF, Bailey CJ, Bodmer J, et al:
Localization of the gene for familial adenomatous polyposis on
chromosome 5. Nature. 328:614–616. 1987. View Article : Google Scholar : PubMed/NCBI
|
8.
|
Fodde R: The APC gene in colorectal
cancer. Eur J Cancer. 38:867–871. 2002. View Article : Google Scholar
|
9.
|
Senda T, Iizuka-Kogo A, Onouchi T and
Shimomura A: Adenomatous polyposis coli (APC) plays multiple roles
in the intestinal and colorectal epithelia. Med Mol Morphol.
40:68–81. 2007. View Article : Google Scholar : PubMed/NCBI
|
10.
|
Powell SM, Zilz N, Beazer-Barclay Y, et
al: APC mutations occur early during colorectal tumorigenesis.
Nature. 359:235–237. 1992. View
Article : Google Scholar : PubMed/NCBI
|
11.
|
Rowan AJ, Lamlum H, Ilyas M, et al: APC
mutations in sporadic colorectal tumors: a mutational ‘hotspot’ and
interdependence of the ‘two hits’. Proc Natl Acad Sci USA.
97:3352–3357. 2000.
|
12.
|
Segditsas S, Sieber OM, Rowan A, et al:
Promoter hypermethylation leads to decreased APC mRNA expression in
familial polyposis and sporadic colorectal tumours, but does not
substitute for truncating mutations. Exp Mol Pathol. 85:201–206.
2008. View Article : Google Scholar
|
13.
|
Ionov Y, Peinado MA, Malkhosyan S, Shibata
D and Percho M: Ubiquitous somatic mutations in simple repeated
sequences reveal a new mechanism for colonic carcinogenesis.
Nature. 363:558–561. 1993. View
Article : Google Scholar : PubMed/NCBI
|
14.
|
Markowitz SD and Bertagnolli MM: Molecular
origins of cancer: molecular basis of colorectal cancer. N Engl J
Med. 361:2449–2460. 2009. View Article : Google Scholar : PubMed/NCBI
|
15.
|
Ribas G, Gonzalez-Neira A, Salas A, et al:
Evaluating HapMap SNP data transferability in a large-scale
genotyping project involving 175 cancer-associated genes. Hum
Genet. 118:669–679. 2006. View Article : Google Scholar : PubMed/NCBI
|
16.
|
Laken SJ, Petersen GM, Gruber SB, et al:
Familial colorectal cancer in Ashkenazim due to a hypermutable
tract in APC. Nat Genet. 17:79–83. 1997. View Article : Google Scholar : PubMed/NCBI
|
17.
|
Gryfe R, Di Nicola N, Gallinger S and
Redston M: Somatic instability of the APC I1307K allele in
colorectal neoplasia. Cancer Res. 58:4040–4043. 1998.PubMed/NCBI
|
18.
|
Frayling IM, Beck NE, Ilyas M, et al: The
APC variants I1307K and E1317Q are associated with colorectal
tumors, but not always with a family history. Pro Natl Acad Sci
USA. 95:10722–10727. 1998. View Article : Google Scholar : PubMed/NCBI
|
19.
|
Lamlum H, Al Tassan N, Jaeger E, et al:
Germline APC variants in patients with multiple colorectal
adenomas, with evidence for the particular inportance of E1317Q.
Hum Mol Genet. 9:2215–2221. 2000. View Article : Google Scholar : PubMed/NCBI
|
20.
|
Azzopardi D, Dallosso AR, Eliason K, et
al: Multiple rare nonsynonymous variants in the adenomatous
polyposis coli gene predispose to colorectal adenomas. Cancer Res.
68:358–363. 2008. View Article : Google Scholar : PubMed/NCBI
|
21.
|
Cui DH, Jiang KD, Jiang SD, Xu YF and Yao
H: The tumour suppressor adenomatous polyposis coli gene is
associated with susceptibility to schizophrenia. Mol Psychiatry.
10:669–677. 2005. View Article : Google Scholar : PubMed/NCBI
|
22.
|
Egan JB, Jacobs ET, Martínez ME, Gerner
EW, Jurutkan PW and Thompson PA: Presence of a TA haplotype in the
APC gene containing the common 1822 polymorphism and colorectal
adenoma. Cancer Res. 68:6006–6013. 2008. View Article : Google Scholar : PubMed/NCBI
|
23.
|
Miller SA, Dykes DD and Polesky HF: A
simple salting out procedure for extracting DNA from human
nucleated cells. Nucleic Acids Res. 16:12151998. View Article : Google Scholar : PubMed/NCBI
|
24.
|
Umar A, Boland CR, Terdiman JP, et al:
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal
cancer (Lynch Syndrome) and microsatellite instability. J Natl
Cancer Inst. 96:261–268. 2004. View Article : Google Scholar
|
25.
|
Ribas G, Milne RL, Gonzalez-Neira A and
Benitez J: Haplotype patterns in cancer-related genes with
long-range linkage disequilibrium: no evidence of association with
breast cancer or positive selection. Eur J Hum Genet. 16:252–260.
2008. View Article : Google Scholar
|