|
1.
|
Rhee JG, Li D, O’Malley BW Jr and
Suntharalingam M: Combination radiation and adenovirus-mediated
P16(INK4A) gene therapy in a murine model for head and neck cancer.
ORL J Otorhinolaryngol Relat Spec. 65:144–154. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
2.
|
Rhee JG, Li D, Suntharalingam M, Guo C,
O’Malley BW Jr and Carney JP: Radiosensitization of head/neck
squamous cell carcinoma by adenovirus-mediated expression of the
Nbs1 protein. Int J Radiat Oncol Biol Phys. 67:273–278. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
3.
|
Takeda K, Noguchi K, Shi W, et al:
Targeted disruption of the mouse Stat3 gene leads to early
embryonic lethality. Proc Natl Acad Sci USA. 94:3801–3804. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
4.
|
Fukada T, Ohtani T, Yoshida Y, et al:
STAT3 orchestrates contradictory signals in cytokine-induced G1 to
S cell-cycle transition. EMBO J. 17:6670–6677. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
5.
|
Catlett-Falcone R, Landowski TH, Oshiro
MM, et al: Constitutive activation of Stat3 signaling confers
resistance to apoptosis in human U266 myeloma cells. Immunity.
10:105–115. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
6.
|
Bromberg JF: Activation of STAT proteins
and growth control. Bioessays. 23:161–169. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
7.
|
Niu G, Wright KL, Ma Y, et al: Role of
Stat3 in regulating p53 expression and function. Mol Cell Biol.
25:7432–7440. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8.
|
Odajima J, Matsumura I, Sonoyama J, et al:
Full oncogenic activities of v-Src are mediated by multiple
signaling pathways. Ras as an essential mediator for cell survival.
J Biol Chem. 275:24096–24105. 2000.PubMed/NCBI
|
|
9.
|
Ning ZQ, Li J, McGuinness M and Arceci RJ:
STAT3 activation is required for Asp(816) mutant c-Kit induced
tumorigenicity. Oncogene. 20:4528–4536. 2001. View Article : Google Scholar
|
|
10.
|
Bowman T, Broome MA, Sinibaldi D, et al:
Stat3-mediated Myc expression is required for Src transformation
and PDGF-induced mitogenesis. Proc Natl Acad Sci USA. 98:7319–7324.
2001. View Article : Google Scholar : PubMed/NCBI
|
|
11.
|
Sinibaldi D, Wharton W, Turkson J, Bowman
T, Pledger WJ and Jove R: Induction of p21WAF1/CIP1 and cyclin D1
expression by the Src oncoprotein in mouse fibroblasts: role of
activated STAT3 signaling. Oncogene. 19:5419–5427. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
12.
|
Karni R, Jove R and Levitzki A: Inhibition
of pp60c-Src reduces Bcl-XL expression and reverses the transformed
phenotype of cells overexpressing EGF and HER-2 receptors.
Oncogene. 18:4654–4662. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
13.
|
Aoki Y, Feldman GM and Tosato G:
Inhibition of STAT3 signaling induces apoptosis and decreases
survivin expression in primary effusion lymphoma. Blood.
101:1535–1542. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
14.
|
Gritsko T, Williams A, Turkson J, et al:
Persistent activation of stat3 signaling induces survivin gene
expression and confers resistance to apoptosis in human breast
cancer cells. Clin Cancer Res. 12:11–19. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
15.
|
Epling-Burnette PK, Liu JH,
Catlett-Falcone R, et al: Inhibition of STAT3 signaling leads to
apoptosis of leukemic large granular lymphocytes and decreased
Mcl-1 expression. J Clin Invest. 107:351–362. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
16.
|
Wei D, Le X, Zheng L, et al: Stat3
activation regulates the expression of vascular endothelial growth
factor and human pancreatic cancer angiogenesis and metastasis.
Oncogene. 22:319–329. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
17.
|
Li X, Wang H, Lu X and Di B: STAT3
blockade with shRNA enhances radiosensitivity in Hep-2 human
laryngeal squamous carcinoma cells. Oncol Rep. 23:345–353.
2010.PubMed/NCBI
|
|
18.
|
Bissery MC, Guenard D, Gueritte-Voegelein
F and Lavelle F: Experimental antitumor activity of taxotere (RP
56976, NSC 628503), a taxol analogue. Cancer Res. 51:4845–4852.
1991.PubMed/NCBI
|
|
19.
|
Crisby M, Nordin-Fredriksson G, Shah PK,
Yano J, Zhu J and Nilsson J: Pravastatin treatment increases
collagen content and decreases lipid content, inflammation,
metalloproteinases, and cell death in human carotid plaques:
implications for plaque stabilization. Circulation. 103:926–933.
2001. View Article : Google Scholar
|
|
20.
|
Weidner N, Semple JP, Welch WR and Folkman
J: Tumor angio-genesis and metastasis – correlation in invasive
breast carcinoma. N Engl J Med. 324:1–8. 1991.
|
|
21.
|
Turkson J and Jove R: STAT proteins: novel
molecular targets for cancer drug discovery. Oncogene.
19:6613–6626. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
22.
|
Bharti AC, Shishodia S, Reuben JM, et al:
Nuclear factor-kappaB and STAT3 are constitutively active in CD138+
cells derived from multiple myeloma patients, and suppression of
these transcription factors leads to apoptosis. Blood.
103:3175–3184. 2004.
|
|
23.
|
Greten FR, Weber CK, Greten TF, et al:
Stat3 and NF-kappaB activation prevents apoptosis in pancreatic
carcinogenesis. Gastroenterology. 123:2052–2063. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
24.
|
Real PJ, Sierra A, De Juan A, Segovia JC,
Lopez-Vega JM and Fernandez-Luna JL: Resistance to chemotherapy via
Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer
cells. Oncogene. 21:7611–7618. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
25.
|
Otero DC, Poli V, David M and Rickert RC:
Cutting edge: inherent and acquired resistance to radiation-induced
apoptosis in B cells: a pivotal role for STAT3. J Immunol.
177:6593–6597. 2006. View Article : Google Scholar
|
|
26.
|
Calvin DP, Nam S, Buettner R, Sekharam M,
Torres-Roca J and Jove R: Inhibition of STAT3 activity with STAT3
antisense oligonucleotide (STAT3-ASO) enhances radiation induced
apoptosis in DU145 prostate cancer cells. Int J Radiat Oncol Biol
Phys. 57:S2972003. View Article : Google Scholar
|
|
27.
|
Zhang YC, Taylor MM, Samson WK and
Phillips MI: Antisense inhibition: oligonucleotides, ribozymes, and
siRNAs. Methods Mol Med. 106:11–34. 2005.PubMed/NCBI
|
|
28.
|
Amin HM, McDonnell TJ, Ma Y, et al:
Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle
arrest in ALK-positive anaplastic large cell lymphoma. Oncogene.
23:5426–5434. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
29.
|
Niu G, Wright KL, Huang M, et al:
Constitutive Stat3 activity up-regulates VEGF expression and tumor
angiogenesis. Oncogene. 21:2000–2008. 2002. View Article : Google Scholar : PubMed/NCBI
|
