Quality of life of lung cancer patients receiving outpatient chemotherapy

Matsuda,Ayako; Kobayashi,Mika; Sakakibara,Yumi; Tamaoka,Meiyo; Furuiye,Masashi; Inase,Naohiko; Matsushima,Eisuke

doi:10.3892/etm.2011.185

March-April 2011 Volume 2 Issue 2

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March-April 2011 Volume 2 Issue 2

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Article

Quality of life of lung cancer patients receiving outpatient chemotherapy

Authors:
- Ayako Matsuda
- Mika Kobayashi
- Yumi Sakakibara
- Meiyo Tamaoka
- Masashi Furuiye
- Naohiko Inase
- Eisuke Matsushima
View Affiliations / Copyright

Affiliations: Department of Liaison Psychiatry and Palliative Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8519, Japan, Department of Integrated Pulmonology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
Pages: 291-294
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Published online on: January 5, 2011

https://doi.org/10.3892/etm.2011.185
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Abstract

An increasing number of cancer patients receive outpatient chemotherapy as an alternative to inpatient chemotherapy. The aim of this study was to investigate whether quality of life (QOL) during outpatient chemotherapy was better than QOL prior to hospital discharge, and to explore possible related factors prior to hospital discharge that affected the QOL of lung cancer patients who received outpatient chemotherapy. Lung cancer inpatients who were scheduled for outpatient chemotherapy were assessed two times (prior to hospital discharge and during outpatient chemotherapy) using the Functional Assessment of Cancer Therapy-Lung and Hospital Anxiety and Depression Scale. A total of 40 patients completed all assessments, both prior to hospital discharge and during outpatient chemotherapy. In the present study, QOL during outpatient chemotherapy was not significantly different when compared with the QOL prior to hospital discharge, and predictors prior to hospital discharge for a better QOL of patients during outpatient chemotherapy included better social, emotional and physical well-being. These results suggest that medical staff, in particular those involved in outpatient chemotherapy, need to recognize social and emotional as well as physical well-being prior to hospital discharge, regardless of cancer-related factors and the personal characteristics of the patients.

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1.	Parkin DM: Global cancer statistics in the year 2000. Lancet Oncol. 2:533–543. 2001.PubMed/NCBI
2.	Center for Cancer Control and Information Services, National Cancer Center, Japan: Data source of Vital Statistics Japan (Ministry of Health, Labour and Welfare). http://ganjoho.ncc.go.jp/professional/statistics/statistics.htmluri. Accessed October 1, 2006 (In Japanese).
3.	Clark R and Ihde DC: Small-cell lung cancer: treatment progress and prospects. Oncology. 12:647–658. 1998.PubMed/NCBI
4.	Novello S and Le Chevaliar T: Chemotherapy for non-small-cell lung cancer. Part 1 Early-stage disease. Oncology. 17:357–364. 2003.PubMed/NCBI
5.	Gridelli C, Perrone F, Nelli F, Ramponi S and De Marinis F: Quality of life in lung cancer patients. Ann Oncol. 12:S21–S25. 2001. View Article : Google Scholar : PubMed/NCBI
6.	Ettinger DS, Akerley W, Bepler G, et al: Non-small cell lung cancer: clinical practice guidelines in oncology. J Natl Compr Canc Netw. 6:228–269. 2008.
7.	De Petris L, Crinò L, Scagliotti GV, et al: Treatment of advanced non-small cell lung cancer. Ann Oncol. 17:ii36–ii41. 2006.
8.	Agra Y, Pelayo M, Sacristan M, Sacristan A, Serra C and Bonfill X: Chemotherapy versus best supportive care for extensive small-cell lung cancer. Cochrane Database Syst Rev. 7:CD0019902009.
9.	Yoneda S: Outpatient chemotherapy for lung cancer. Gan To Kagaku Ryoho. 34:533–537. 2007.(In Japanese).
10.	Ishiura Y, Yamamoto H, Terasaki Y, et al: Analysis of factors associated with quality of life for patients with non-small lung cancer receiving outpatient vinorelbine therapy as alternative inpatient therapy. Gan To Kagaku Ryoho. 34:1401–1404. 2007.(In Japanese).
11.	American Society of Clinical Oncology: Outcomes of cancer treatment for technology assessment and cancer treatment guidelines. J Clin Oncol. 14:671–679. 1996.PubMed/NCBI
12.	Montazeri A, Gillis CR and McEwen J: Quality of life in patients with lung cancer. Chest. 113:467–481. 1998. View Article : Google Scholar : PubMed/NCBI
13.	Cella DF, Bonomi AE, Lloyd SR, Tulsky DS, Kaplan E and Bonomi P: Reliability and validity of the Functional Assessment of Cancer Therapy-Lung (FACT-L) quality of life instrument. Lung Cancer. 12:199–220. 1995. View Article : Google Scholar : PubMed/NCBI
14.	Zigmond AS and Snaith RP: The hospital anxiety and depression scale. Acta Psychiatr Scand. 67:361–370. 1983. View Article : Google Scholar : PubMed/NCBI
15.	Kugaya A, Akechi T, Okuyama T, Okamura H and Uchitomi Y: Screening for psychological distress in Japanese cancer patients. Jpn J Clin Oncol. 28:333–338. 1998. View Article : Google Scholar : PubMed/NCBI
16.	Freedman OC and Zimmermann C: The role of palliative care in the lung cancer patient: can we improve quality while limiting futile care? Curr Opin Pulm Med. 15:321–326. 2009. View Article : Google Scholar : PubMed/NCBI
17.	McCorkle R and Quint-Benoliel J: Symptom distress, current concerns and mood disturbance after diagnosis of life-threatening disease. Soc Sci Med. 17:431–438. 1983. View Article : Google Scholar : PubMed/NCBI
18.	Hopwood P and Stephens RJ: Depression in patients with lung cancer: Prevalence and risk factors derived from quality-of-life data. J Clin Oncol. 18:893–903. 2000.PubMed/NCBI
19.	Derogatis LR, Morrow GR, Fetting J, et al: The prevalence of psychiatric disorders among cancer patients. JAMA. 249:751–757. 1983. View Article : Google Scholar : PubMed/NCBI
20.	Hollen PJ, Gralla RJ, Kris MG, et al: Measurement of quality of life in patients with lung cancer in multicenter trials of new therapies. Psychometric assessment of the Lung Cancer Symptom Scale. Cancer. 73:2087–2098. 1994. View Article : Google Scholar : PubMed/NCBI
21.	Gralla RJ and Thatcher N: Quality-of-life assessment in advanced lung cancer: considerations for evaluation in patients receiving chemotherapy. Lung Cancer. 46:S41–S47. 2004. View Article : Google Scholar : PubMed/NCBI
22.	Mystakidou K, Tsilika E, Parpa E, Smyrnioti M and Vlahos L: Assessment of anxiety and depression in advanced cancer patients and their relationship with quality of life. Qual Life Res. 14:1825–1833. 2005. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Quality of life of lung cancer patients receiving outpatient chemotherapy

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