Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
October 2012 Volume 4 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October 2012 Volume 4 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis

  • Authors:
    • Xueying Hu
    • Yang Zhou
    • Jianxiong Long
    • Qiming Feng
    • Rensheng Wang
    • Li Su
    • Tingting Zhao
    • Bo Wei
  • View Affiliations / Copyright

    Affiliations: School of Public Health, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, P.R. China, Department of Radiotherapy, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, P.R. China
  • Pages: 665-668
    |
    Published online on: August 14, 2012
       https://doi.org/10.3892/etm.2012.665
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

This aim of this study was to assess the diagnostic accuracy of the International HIV Dementia Scale (IHDS) or HIV Dementia Scale (HDS) for the diagnosis of HIV-associated neurocognitive disorders (HAND). A comprehensive and systematic search was carried out in PubMed and EMBASE databases. Sensitivity, specificity, Q*-values, summary receiver operating characteristic curves and other measures of accuracy of IHDS or HDS in the diagnosis of HAND were summarized. Summary receiver operator characteristic (SROC) curve analysis for HAND data demonstrates a pooled sensitivity of 0.90 [95% confidence interval (CI), 0.88-0.91] and overall specificity of 0.96 (95% CI, 0.95‑0.97) for IHDS, the Q*-value for IHDS was 0.9195 and the diagnostic odds ratio (DOR) was 162.28 (95% CI, 91.82‑286.81). HDS had an overall sensitivity of 0.39 (95% CI, 0.34‑0.43) and specificity of 0.90 (95% CI, 0.89‑0.91), the Q*-value for HDS was 0.6321 and DOR was 5.81 (95% CI, 3.64‑9.82). There was significant heterogeneity for studies that reported IHDS and HDS. This meta-analysis has shown that IHDS and HDS may offer high diagnostic performance accuracy for the detection of HAND in primary health care and resource-limited settings. IHDS and HDS may require reformed neuropsychological characterization of impairments in accordance with regional culture and language in future international studies.
View Figures
View References

1 

Joint United Nations Program on HIV/AIDS (UNAIDS) and World Health Organization (WHO): AIDS Epidemic Update. UNAIDS; Geneva: 2003

2 

Heaton RK, Clifford DB, Franklin DR Jr, et al: HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study. Neurology. 75:2087–2096. 2010. View Article : Google Scholar

3 

Robertson KR, Smurzynski M, Parsons TD, et al: The prevalence and incidence of neurocognitive impairment in the HAART era. AIDS. 21:1915–1921. 2007. View Article : Google Scholar : PubMed/NCBI

4 

Simioni S, Cavassini M, Annoni JM, et al: Cognitive dysfunction in HIV patients despite long-standing suppression of viremia. AIDS. 24:1243–1250. 2010.PubMed/NCBI

5 

Pumpradit W, Ananworanich J, Lolak S, et al: Neurocognitive impairment and psychiatric comorbidity in well-controlled human immunodeficiency virus-infected Thais from the 2NN Cohot Study. J Neurovirol. 16:76–82. 2010. View Article : Google Scholar

6 

Sacktor N, McDermott MP, Marder K, et al: HIV-associated cognitive impairment before and after the advent of combination therapy. J Neurovirol. 8:136–142. 2002. View Article : Google Scholar : PubMed/NCBI

7 

Gorman AA, Foley JM, Ettenhofer ML, Hinkin CH and van Gorp WG: Functional consequences of HIV-associated neuropsychological impairment. Neuropsychol Rev. 19:186–203. 2009. View Article : Google Scholar : PubMed/NCBI

8 

Antinori A, Arendt G, Becker JT, et al: Updated research nosology for HIV-associated neurocognitive disorders. Neurology. 69:1789–1799. 2007. View Article : Google Scholar : PubMed/NCBI

9 

Nomenclature and research case definitions for neurological manifestations of human immunodeficiency virus type-1 (HIV-1) infection. Report of a Working Group of the American Academy of Neurology AIDS Task Force. Neurology. 41:778–785. 1991. View Article : Google Scholar

10 

Folstein MF, Folstein SE and McHugh PR: Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 12:189–198. 1975.

11 

Bleecker ML, Bolla-Wilson K, Kawas C and Agnew J: Age-specific norms for the Mini-Mental State Exam. Neurology. 38:1565–1568. 1988. View Article : Google Scholar : PubMed/NCBI

12 

Sacktor NC, Wong M, Nakasujja N, et al: The International HIV Dementia Scale: a new rapid screening test for HIV dementia. AIDS. 19:1367–1374. 2005.PubMed/NCBI

13 

Singh D, Sunpath H, John S, Eastham L and Gouden R: The utility of a rapid screening tool for depression and HIV dementia amongst patients with low CD4 counts - a preliminary report. Afr J Psychiatry (Johannesbg). 11:282–286. 2008.

14 

Skinner S, Adewale AJ, DeBlock L, Gill MJ and Power C: Neurocognitive screening tools in HIV/AIDS: comparative performance among patients exposed to antiretroviral therapy. HIV Med. 10:246–252. 2009. View Article : Google Scholar : PubMed/NCBI

15 

Joska JA, Westgarth-Taylor J, Hoare J, et al: Validity of the International HIV Dementia Scale in South Africa. AIDS Patient Care STDS. 25:95–101. 2011. View Article : Google Scholar : PubMed/NCBI

16 

Power C, Selnes OA, Grim JA and McArthur JC: HIV Dementia Scale: a rapid screening test. J Acquir Immune Defic Syndr Hum Retrovirol. 8:273–278. 1995. View Article : Google Scholar : PubMed/NCBI

17 

Berghuis JP, Uldall KK and Lalonde B: Validity of two scales in identifying HIV-associated dementia. J Acquir Immune Defic Syndr. 21:134–140. 1999.PubMed/NCBI

18 

Smith CA, van Gorp WG, Ryan ER, Ferrando SJ and Rabkin J: Screening subtle HIV-related cognitive dysfunction: the clinical utility of the HIV dementia scale. J Acquir Immune Defic Syndr. 33:116–118. 2003. View Article : Google Scholar : PubMed/NCBI

19 

Carey CL, Woods SP, Rippeth JD, et al: Initial validation of a screening battery for the detection of HIV-associated cognitive impairment. Clin Neuropsychol. 18:234–248. 2004. View Article : Google Scholar : PubMed/NCBI

20 

Wojna V, Skolasky RL, McArthur JC, et al: Spanish validation of the HIV dementia scale in women. AIDS Patient Care STDS. 21:930–941. 2007. View Article : Google Scholar : PubMed/NCBI

21 

Lyon ME, McCarter R and D’Angelo LJ: Detecting HIV associated neurocognitive disorders in adolescents: what is the best screening tool? J Adolesc Health. 44:133–135. 2009. View Article : Google Scholar : PubMed/NCBI

22 

Whiting PF, Weswood ME, Rutjes AW, Reitsma JB, Bossuyt PN and Kleijnen J: Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies. BMC Med Res Methodol. 6:92006. View Article : Google Scholar : PubMed/NCBI

23 

Zamora J, Abraira V, Muriel A, et al: Meta-DiSc: a software for meta-analysis of test accuracy data. BMC Med Res Methodol. 6:312006. View Article : Google Scholar : PubMed/NCBI

24 

Choi Y, Townend J, Vincent T, et al: Neurologic manifestations of human immunodeficiency virus-2: dementia, myelopathy, and neuropathy in West Africa. J Neurovirol. 17:166–175. 2011. View Article : Google Scholar : PubMed/NCBI

25 

Morgan EE, Woods SP, Scott JC, et al: Predictive validity of demographically adjusted normative standards for the HIV Dementia Scale. J Clin Exp Neuropsychol. 30:83–90. 2008. View Article : Google Scholar : PubMed/NCBI

26 

Bottiggi KA, Chang JJ, Schmitt FA, et al: The HIV Dementia Scale: predictive power in mild dementia and HAART. J Neurolsci. 260:11–15. 2007.PubMed/NCBI

27 

von Giesen HJ, Haslinger BA, Rohe S, Köller H and Arendt G: HIV Dementia Scale and psychomotor slowing - the best methods in screening for neuro-AIDS. J Neuropsychiatry Clin Neurosci. 17:185–191. 2005.PubMed/NCBI

28 

Ganasen KA, Fincham D, Smit J, Seedat S and Stein D: Utility of the HIV Dementia Scale (HDS) in identifying HIV dementia in a South African sample. J Neurol Sci. 269:62–64. 2008. View Article : Google Scholar : PubMed/NCBI

29 

McArthur JC, Cohen BA, Selnes OA, et al: Low prevalence of neurological and neuropsychological abnormalities in otherwise healthy HIV-1-infected individuals: results from the multicenter AIDS Cohort Study. Ann Neurol. 26:601–611. 1989. View Article : Google Scholar

30 

Sacktor NC, Bacellar H, Hoover DR, et al: Psychomotor slowing in HIV infection: a predictor of dementia, AIDS and death. J Neurovirol. 2:404–410. 1996. View Article : Google Scholar : PubMed/NCBI

31 

Hinkin CH, Hardy DJ, Mason KI, et al: Medication adherence in HIV-infected adults: effect of patient age, cognitive status, and substance abuse. AIDS. 18(Suppl 1): S19–S25. 2004. View Article : Google Scholar : PubMed/NCBI

32 

Sacktor N, Lyles RH, Skolasky RL, et al: Combination antiretroviral therapy improves psychomotor speed performance in HIV-seropositive homosexual men. Neurology. 52:1640–1647. 1999. View Article : Google Scholar : PubMed/NCBI

33 

Sacktor N, Skolasky RL, Lyles RH, Esposito D, Selnes OA and McArthur JC: Improvement in HIV-associated motor slowing after antiretroviral therapy including protease inhibitors. J Neurovirol. 6:84–88. 2000. View Article : Google Scholar : PubMed/NCBI

34 

Pham B, Platt R, McAuley L, et al: Is there a ‘best’ way to detect and minimize publication bias? An empirical evaluation. Eval Health Prof. 24:109–125. 2001.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Hu X, Zhou Y, Long J, Feng Q, Wang R, Su L, Zhao T and Wei B: Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis. Exp Ther Med 4: 665-668, 2012.
APA
Hu, X., Zhou, Y., Long, J., Feng, Q., Wang, R., Su, L. ... Wei, B. (2012). Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis. Experimental and Therapeutic Medicine, 4, 665-668. https://doi.org/10.3892/etm.2012.665
MLA
Hu, X., Zhou, Y., Long, J., Feng, Q., Wang, R., Su, L., Zhao, T., Wei, B."Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis". Experimental and Therapeutic Medicine 4.4 (2012): 665-668.
Chicago
Hu, X., Zhou, Y., Long, J., Feng, Q., Wang, R., Su, L., Zhao, T., Wei, B."Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis". Experimental and Therapeutic Medicine 4, no. 4 (2012): 665-668. https://doi.org/10.3892/etm.2012.665
Copy and paste a formatted citation
x
Spandidos Publications style
Hu X, Zhou Y, Long J, Feng Q, Wang R, Su L, Zhao T and Wei B: Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis. Exp Ther Med 4: 665-668, 2012.
APA
Hu, X., Zhou, Y., Long, J., Feng, Q., Wang, R., Su, L. ... Wei, B. (2012). Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis. Experimental and Therapeutic Medicine, 4, 665-668. https://doi.org/10.3892/etm.2012.665
MLA
Hu, X., Zhou, Y., Long, J., Feng, Q., Wang, R., Su, L., Zhao, T., Wei, B."Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis". Experimental and Therapeutic Medicine 4.4 (2012): 665-668.
Chicago
Hu, X., Zhou, Y., Long, J., Feng, Q., Wang, R., Su, L., Zhao, T., Wei, B."Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis". Experimental and Therapeutic Medicine 4, no. 4 (2012): 665-668. https://doi.org/10.3892/etm.2012.665
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team