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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2012 Volume 4 Issue 4

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Impact Factor: 2.3

Review

Genotoxicity and carcinogenicity of cobalt-, nickel- and copper-based nanoparticles (Review)

Ruth Magaye, Jinshun Zhao, Linda Bowman, Min Ding
Pages: 551-561
Published online on: 07 August 2012

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Article

First-line single-agent chemotherapy for patients with recurrent or metastatic gastric cancer with poor performance status

Jun-Eul Hwang, Ha-Na Kim, Dae-Eun Kim, Hyun-Jeong Shim, Woo-Kyun Bae, Eu-Chang Hwang, Sang-Hee Cho, Ik-Joo Chung
Pages: 562-568
Published online on: 23 July 2012

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Article

MDM2 SNP309 polymorphism is associated with lung cancer risk in women: A meta-analysis using METAGEN

Wenwu He, Jianxiong Long, Lei Xian, Feng Pang, Li  Su, Shixiu Wei, Bo Wei, Yanling Hu
Pages: 569-576
Published online on: 18 July 2012

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Article

Evaluation of the effect of a chicken comb extract-containing supplement on cartilage and bone metabolism in athletes

Masafumi Yoshimura, Yukihiro Aoba, Taiji Watari, Rei Momomura, Keita Watanabe, Akihito Tomonaga, Michitaka Matsunaga, Yoshimasa Suda, Woo Young Lee, Katsuhito Asai, Kaori Yoshimura, Takashi Nakagawa, Tetsuro Yamamoto, Hideyo Yamaguchi, Isao Nagaoka
Pages: 577-580
Published online on: 24 July 2012

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Article

Serum prohepcidin levels are potential prognostic markers in patients with multiple myeloma

Kouichi Haraguchi, Hirofumi Uto, Nobuhito Ohnou, Masahito Tokunaga, Mayumi Tokunaga, Atae Utsunomiya, Shuichi Hanada, Hirohito Tsubouchi
Pages: 581-588
Published online on: 13 August 2012

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Article

Expression of thymidylate synthase and orotate phosphoribosyltransferase in thymic carcinoma

Keisuke Yokota, Hidefumi Sasaki, Katsuhiro Okuda, Masayuki Shitara, Yu Hikosaka, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii
Pages: 589-593
Published online on: 19 July 2012

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Article

Propranolol treatment of infantile hemangioma endothelial cells: A molecular analysis

Jessica Stiles, Clarissa Amaya, Robert Pham, Rebecca K. Rowntree, Mary Lacaze, Arlynn Mulne, Joyce Bischoff, Victor Kokta, Laura E. Boucheron, Dianne C. Mitchell, Brad A. Bryan
Pages: 594-604
Published online on: 03 August 2012

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Article

Stellera chamaejasme L. extract induces apoptosis of human lung cancer cells via activation of the death receptor-dependent pathway

Xiaoni Liu, Xiaoxin Zhu
Pages: 605-610
Published online on: 20 July 2012

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Article

Study of the role of epidermal growth factor on lung fluid transport in rabbits with acute lung injury caused by endotoxin

Binou Yang, Weiqing Huang, Jieyun Han, Zijing Liang
Pages: 611-614
Published online on: 16 August 2012

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Article

Diet-induced obesity potentiates the growth of gastric cancer in mice

Hai-Jun Li, Xiang-Ming Che, Wei Zhao, Shi-Cai He, Zheng-Liang Zhang, Rui Chen
Pages: 615-620
Published online on: 07 August 2012

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Article

Effect of enhanced expression of COL8A1 on lymphatic metastasis of hepatocellular carcinoma in mice Retraction in /10.3892/etm.2026.13098

Zhen-Hai Ma, Jin-Hui Ma, Li Jia, Yong-Fu Zhao
Pages: 621-626
Published online on: 01 August 2012

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Article

Antidepressant effect of geranylgeranylacetone in a chronic mild stress model of depression and its possible mechanism

Jing-Mei Zhong, Shao-Yuan Wu, Jie Bai, Qiang Guo, Jian Tao, Hui Chen, Nai-Wei Zhao, Zhong Zhao, Hao Fu
Pages: 627-632
Published online on: 16 August 2012

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Article

Relationship between expression and prognostic ability of PTEN, STAT3 and VEGF-C in colorectal cancer

Canhui Jin, Aihong Wang, Jianmin Chen, Xiaomin Liu, Gongping Wang
Pages: 633-639
Published online on: 31 July 2012

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Article

Evaluation of the effect of methionine and glucosamine on adjuvant arthritis in rats

Yoshie Yamagishi, Mamoru Igarashi, Atsuko Suzuki, Shiori  Suguro, Shin-Ichi Hirano, Isao Nagaoka
Pages: 640-644
Published online on: 16 August 2012

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Article

Protective effects of capillary artemisia polysaccharide on oxidative injury to the liver in rats with obstructive jaundice

Chang-Sheng He, Hong-Yi Yue, Jian Xu, Feng Xue, Jian Liu, Yuan-Yuan Li, Hong-En Jing
Pages: 645-648
Published online on: 14 August 2012

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Article

Embelin-induced apoptosis of HepG2 human hepatocellular carcinoma cells and blockade of HepG2 cells in the G2/M phase via the mitochondrial pathway

Asaf Taghiyev, Deguang Sun, Zhen Ming Gao, Rui Liang, Liming Wang
Pages: 649-654
Published online on: 11 July 2012

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Article

Co-transfection of dendritic cells with AFP and IL-2 genes enhances the induction of tumor antigen-specific antitumor immunity

Jing-Yue Yang, Xiao Li, Li Gao, Zeng-Hui Teng, Wen-Chao Liu
Pages: 655-660
Published online on: 06 July 2012

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Case Report

Challenging delivery of VLHL NS plasminogen activator inhibitor-1 by osmotic pumps in diabetic mouse: A case report

Jerzy Jankun
Pages: 661-664
Published online on: 17 July 2012

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Article

Diagnostic accuracy of the International HIV Dementia Scale and HIV Dementia Scale: A meta-analysis

Xueying Hu, Yang Zhou, Jianxiong Long, Qiming Feng, Rensheng Wang, Li Su, Tingting Zhao, Bo Wei
Pages: 665-668
Published online on: 14 August 2012

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Article

Impact of intense pulsed light irradiation on cultured primary fibroblasts and a vascular endothelial cell line

Di Wu, Bingrong Zhou, Yang Xu, Zhiqiang Yin, Dan Luo
Pages: 669-674
Published online on: 14 August 2012

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Article

Comparison of subcutaneous central venous port via jugular and subclavian access in 347 patients at a single center

Bilgin Kadri Aribaş, Kemal Arda, Özge Aribaş, Nazan Çiledağ, Zeynel Yoloğlu, Elif Aktaş, Turgut Seber, Şeyhmus Kavak, Yusuf Coşar, Hidir Kaygusuz, Ekrem Tekin
Pages: 675-680
Published online on: 30 July 2012

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Article

Effects of low doses of estrone on the proliferation, differentiation and mineralization of osteoprecursor cells

Jun-Beom Park
Pages: 681-684
Published online on: 03 August 2012

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Article

Simultaneous transurethral resection of bladder cancer and prostate may reduce recurrence rates: A systematic review and meta-analysis

Sheng Li, Xian-Tao Zeng, Xiao-Lan Ruan, Xing-Huan Wang, Yi Guo, Zhong-Hua Yang
Pages: 685-692
Published online on: 09 August 2012

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Article

Clinical impact of 18F-FDG PET/CT on initial staging and therapy planning for breast cancer

Bengul Gunalp, Semra Ince, Alper Ozgur Karacalioglu, Asli Ayan, Ozdes Emer, Engin Alagoz
Pages: 693-698
Published online on: 09 August 2012

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Article

Red clover extract exerts antidiabetic and hypolipidemic effects in db/db mice

Longxin Qiu, Tong Chen, Fojin Zhong, Yamin Hong, Limei Chen, Hong Ye
Pages: 699-704
Published online on: 09 August 2012

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Article

Detection of active P‑glycoprotein in systemic lupus erythematosus patients with poor disease control

Bo Zhang, Ying Shi, Tie‑Chi Lei
Pages: 705-710
Published online on: 16 August 2012

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Article

Comparison of the characteristics of mesenchymal stem cells obtained from prostate tumors and from bone marrow cultured in conditioned medium

Guanxiong Ding, Jialiang Shao, Qiang Ding, Zujun Fang, Zhong Wu, Jianfeng Xu, Peng Gao
Pages: 711-715
Published online on: 20 July 2012

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Article

Effect of NF-κB inhibitors on the chemotherapy-induced apoptosis of the colon cancer cell line HT-29

Ting Liu, Dan Liu, Jing Liu, Ji-Tao Song, Shan-Ling Gao, Hui Li, Li-Hong Hu, Bing-Rong Liu
Pages: 716-722
Published online on: 24 July 2012

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Article

Complement factor C5a and C5a receptor contribute to morphine tolerance and withdrawal-induced hyperalgesia in rats

Yan-Hua Li, Hua Jin, Jing-Shu Xu, Guang-Qiong Guo, Da-Lin Chen, Yun Bo
Pages: 723-727
Published online on: 10 July 2012

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Article

The -149C>T polymorphism of DNMT3B is not associated with colorectal cancer risk: Evidence from a meta-analysis based on case-control studies

Chunyan Fang, Wenqi Sun, Huirong Han, Lihong Shi, Lin Wang, Yan Zhao, Yang Tan
Pages: 728-732
Published online on: 17 July 2012

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Article

Detection of benign proliferative lesions on vocal cords with voice handicap index

Xuekun Huang, Gehua Zhang, Xiujin Liu, Tao Wang, Ling Zhu
Pages: 733-735
Published online on: 24 July 2012

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Article

The membrane-cytoskeletal protein 4.1N is involved in the process of cell adhesion, migration and invasion of breast cancer cells

Zhenyu Ji, Xiaofang Shi, Xin Liu, Yu Shi, Qingqing Zhou, Xilong Liu, Li Li, Xiang Ji, Yanfeng Gao, Yuanming Qi, Qiaozhen Kang
Pages: 736-740
Published online on: 03 August 2012

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Article

Association of angiotensin‑converting enzyme gene I/D and CYP11B2 gene -344T/C polymorphisms with lone atrial fibrillation and its recurrence after catheter ablation

Xian-Ling Zhang, Li-Qun Wu, Xu Liu, Yi-Qing Yang, Hong-Wei Tan, Xin-Hua Wang, Li Zhou, Wei-Feng Jiang, Zheng Li
Pages: 741-747
Published online on: 31 July 2012

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Article

Lack of association of the cyclin D1 G870A variation with oral carcinoma risk: Evidence from 2,404 subjects

Xian-Lu Zhuo, Jun-Jun Ling, Hou-Yu Zhao, Yan Zhou, Yu-Feng Song, Ying-Hui Tan
Pages: 748-754
Published online on: 24 July 2012

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Article

Effects of siRNA-mediated knockdown of jumonji domain containing 2A on proliferation, migration and invasion of the human breast cancer cell line MCF-7

Bei-Xu Li, Cheng-Liang Luo, Hui Li, Peng Yang, Ming-Chang Zhang, Hong-Mei Xu, Hong-Fei Xu, Yi-Wen Shen, Ai-Min Xue, Zi-Qin Zhao
Pages: 755-761
Published online on: 13 August 2012

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Article

CASP-8 -652 6N ins/del polymorphism and cancer risk: A literature-based systematic HuGE review and meta-analysis

Da Chen, Tao Ma, Xiao-Wei Liu, Zhi Liu
Pages: 762-770
Published online on: 13 August 2012

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.3

Review Open Access

FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
Published online on: 26 March 2026

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Article Open Access

A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
Article Number: 145
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Article

Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Article Open Access

Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
Article Number: 142
Published online on: 19 March 2026

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Article Open Access

Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
Article Number: 141
Published online on: 19 March 2026

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Review Open Access

Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
Published online on: 19 March 2026

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Review Open Access

Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Article Open Access

Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
Published online on: 19 March 2026

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Review Open Access

Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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Retraction Open Access

[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Article Open Access

Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
Article Number: 135
Published online on: 13 March 2026

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Article Open Access

Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Article

Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Article Open Access

Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Article Open Access

Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Article

Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Case Report Open Access

Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Article

Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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Article Open Access

RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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Article Open Access

A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.3

Article Open Access

Effects of rok1 gene deletion on mitosis in fission yeast at appropriate and stressful temperatures and the molecular mechanisms

Jiayi He, Mengnan Liu, Jiani Xu, Xiang Ding, Yiling Hou
Article Number: 151
Published online on: 02 April 2026

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Review Open Access

Therapeutic potential of allicin against viral infections: Mechanisms and safety profile (Review)

Ming-Jun Yu, Yong Zhu, Wei Zhang, Qiao-Ping Xu, Hai-Ming Wang, Zhao Ma
Article Number: 150
Published online on: 02 April 2026

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Interacting proteins of AMPK studied using TurboID proximity labeling technology

Xiaoshan Liu, Jieyu Guo, Qiongyao Wang, Wu Liu, Yan Xue, Shuang Guo, Miao Li
Article Number: 149
Published online on: 02 April 2026

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Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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