Comparison of the toxicity of aqueous and ethanol fractions of Angelica keiskei leaf using the eye irritancy test

Sørensen JM: Herb-drug, food-drug, nutrient-drug, and drug-drug interactions: mechanisms involved and their medical implications. J Altern Complement Med. 8:293–308. 2002.PubMed/NCBI

Pan MH, Lai CS, Dushenkov S and Ho CT: Modulation of inflammatory genes by natural dietary bioactive compounds. J Agric Food Chem. 57:4467–4477. 2009. View Article : Google Scholar : PubMed/NCBI

Pan MH, Ghai G and Ho CT: Food bioactives, apoptosis, and cancer. Mol Nutr Food Res. 52:43–52. 2008. View Article : Google Scholar : PubMed/NCBI

Sarker SD and Nahar L: Natural medicine: the genus Angelica. Curr Med Chem. 11:1479–1500. 2004. View Article : Google Scholar : PubMed/NCBI

Piersen CE: Phytoestrogens in botanical dietary supplements: implications for cancer. Integr Cancer Ther. 2:120–138. 2003. View Article : Google Scholar

Lopes D and Strobl H: Kolodziejczyk P: 14-Methylpentadecano-15-lactone (muscolide): a new macrocyclic lactone from the oil of Angelica keiskei L. Chem Biodivers. 1:1880–1887. 2004. View Article : Google Scholar : PubMed/NCBI

Sigurdsson S, Ogmundsdottir HM and Gudbjarnason S: Antitumour activity of Angelica keiskei leaf extract. In Vivo. 19:191–194. 2005.

Sigurdsson S, Ogmundsdottir HM and Gudbjarnason S: The cytotoxic effect of two chemotypes of essential oils from the fruits of Angelica keiskei L. Anticancer Res. 25:1877–1880. 2005.PubMed/NCBI

Yeh ML, Liu CF, Huang CF and Huang TC: Hepatoprotective effect of Angelica keiskei in chronically ethanol-treated mice. Pharmacology. 68:70–73. 2003.

Heo JC and Lee SH: Amelioration of asthmatic-related symptoms by an aqueous extract of Angelica archangelica L. J Life Sci. 18:1336–1341. 2008. View Article : Google Scholar

Tavaszi J, Budai P, Pálovics A and Kismányoki A: An alternative test battery in detecting ocular irritancy of agrochemicals. Commun Agric Appl Biol Sci. 73:891–895. 2008.PubMed/NCBI

Scott L, Eskes C, Hoffmann S, Adriaens E, Alepée N, Bufo M, Clothier R, Facchini D, Faller C, Guest R, et al: A proposed eye irritation testing strategy to reduce and replace in vivo studies using bottom-up and top-down approaches. Toxicol In Vitro. 24:1–9. 2010. View Article : Google Scholar : PubMed/NCBI

Osborne R, Perkins MA and Roberts DA: Development and intralaboratory evaluation of an in vitro human cell-based test to aid ocular irritancy assessments. Fundam Appl Toxicol. 28:139–153. 1995. View Article : Google Scholar : PubMed/NCBI

Nigam PK: Adverse reactions to cosmetics and methods of testing. Indian J Dermatol Venereol Leprol. 75:10–18. 2009. View Article : Google Scholar : PubMed/NCBI

Zimmermann M: Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 16:109–110. 1983. View Article : Google Scholar : PubMed/NCBI

Draize JH, Woodard G and Calvery HO: Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J Pharmacol Exp Ther. 82:377–390. 1944.

Aoshima H, Saitoh Y, Ito S, Yamana S and Miwa N: Safety evaluation of highly purified fullernenes: based on screening of eye and skin damage. J Toxicol Sci. 34:555–562. 2009. View Article : Google Scholar : PubMed/NCBI

Draize JH: Dermal toxicity. Appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics. Association of Food and Drug Officials of the United States. Texas State Departmemt of Health; Austin, Texas: pp. 46–59. 1959

Heo JC, Park JY, Kwon TK, Chung SK, Kim SU and Lee SH: Development of high-throughput screening method for anti-asthmatic agents by food-derived libraries. Korean J Food Preserv. 12:267–274. 2005.

Heo JC, Woo SW, Kweon MA, Park JY, Lee HK, Son M, Rho JR and Lee SH: Aqueous extract of a seed from Helianthus annuus alleviates asthmatic symptoms in vivo. Int J Mol Med. 21:57–61. 2008.

Korting HC, Herzinger T, Hartinger A, Kerscher M, Angerpointner T and Maibach HI: Discrimination of the irritancy potential of surfactants in vitro by two cytotoxicity assays using normal human keratinocytes, HaCaT cells and 3T3 mouse fibroblasts: correlation with in vivo data from a soap chamber assay. J Dermatol Sci. 7:119–129. 1994. View Article : Google Scholar

Tardiff RG, Hubner RP and Graves CG: Harmonization of thresholds for primary skin irritation from results of human repeated insult patch tests and laboratory animal skin irritation tests. J Appl Toxicol. 23:279–281. 2003. View Article : Google Scholar : PubMed/NCBI

Basketter DA and Kimber I: Skin irritation, false positives and the local lymph node assay: a guideline issue? Regul Toxicol Pharmacol. 61:137–140. 2011. View Article : Google Scholar : PubMed/NCBI