|
1
|
Bernaudin M, Marti HH, Roussel S, Divoux
D, Nouvelot A, MacKenzie ET and Petit E: A potential role for
erythropoietin in focal permanent cerebral ischemia in mice. J
Cereb Blood Flow Metab. 19:643–651. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Sakanaka M, Wen TC, Matsuda S, Masuda S,
Morishita E, Nagao M and Sasaki R: In vivo evidence that
erythropoietin protects neurons from ischemic damage. Proc Natl
Acad Sci USA. 95:4635–4640. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Siren AL, Fratelli M, Brines M, Goemans C,
Casagrande S, Lewczuk P, Keenan S, Gleiter C, Pasquali C,
Capobianco A, et al: Erythropoietin prevents neuronal apoptosis
after cerebral ischemia and metabolic stress. Proc Natl Acad Sci
USA. 98:4044–4049. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Brines M and Cerami A: Emerging biological
roles for erythropoietin in the nervous system. Nat Rev Neurosci.
6:484–494. 2005. View
Article : Google Scholar : PubMed/NCBI
|
|
5
|
Eid T and Brines M: Recombinant human
erythropoietin for neuroprotection: what is the evidence? Clin
Breast Cancer. 3(Suppl 3): S109–S115. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Tan CC, Eckardt KU, Firth JD and Ratcliffe
PJ: Feedback modulation of renal and hepatic erythropoietin mRNA in
response to graded anemia and hypoxia. Am J Physiol. 263:F474–F481.
1992.PubMed/NCBI
|
|
7
|
Marti HH, Wenger RH, Rivas LA, Straumann
U, Digicaylioglu M, Henn V, Yonekawa Y, Bauer C and Gassmann M:
Erythropoietin gene expression in human, monkey and murine brain.
Eur J Neurosci. 8:666–676. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kilic E, Kilic U, Soliz J, Bassetti CL,
Gassmann M and Hermann DM: Brain-derived erythropoietin protects
from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt
pathways. FASEB J. 19:2026–2028. 2005.PubMed/NCBI
|
|
9
|
Yatsiv I, Grigoriadis N, Simeonidou C,
Stahel PF, Schmidt OI, Alexandrovitch AG, Tsenter J and Shohami E:
Erythropoietin is neuroprotective, improves functional recovery,
and reduces neuronal apoptosis and inflammation in a rodent model
of experimental closed head injury. FASEB J. 19:1701–1703.
2005.
|
|
10
|
Boran BO, Colak A and Kutlay M:
Erythropoietin enhances neurological recovery after experimental
spinal cord injury. Restor Neuro Neurosci. 23:341–345.
2005.PubMed/NCBI
|
|
11
|
Gorio A, Gokmen N, Erbayraktar S, Yilmaz
O, Madaschi L, Cichetti C, Di Giulio AM, Vardar E, Cerami A and
Brines M: Recombinant human erythropoietin counteracts secondary
injury and markedly enhances neurological recovery from
experimental spinal cord trauma. Proc Natl Acad Sci USA.
99:9450–9455. 2002. View Article : Google Scholar
|
|
12
|
Lu D, Mahmood A, Qu C, Goussev A,
Schallert T and Chopp M: Erythropoietin enhances neurogenesis and
restores spatial memory in rats after traumatic brain injury. J
Neurotrauma. 22:1011–1017. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Kalialis LV and Olsen NV: Erythropoietin –
a new therapy in cerebral ischemia? Ugeskr Laeger. 165:2477–2481.
2003.(In Danish).
|
|
14
|
Buemi M, Cavallaro E, Floccari F, Sturiale
A, Aloisi C, Trimarchi M, Grasso G, Corica F and Frisina N:
Erythropoietin and the brain: from neurodevelopment to
neuroprotection. Clin Sci (Lond). 103:275–282. 2002.PubMed/NCBI
|
|
15
|
Feeney DM, Boyeson MG, Linn RT, Murray HM
and Dail WG: Responses to cortical injury: I. Methodology and local
effects of contusions in the rat. Brain Res. 211:67–77. 1981.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Mammis A, McIntosh TK and Maniker AH:
Erythropoietin as a neuroprotective agent in traumatic brain injury
Review. Surg Neurol. 71:527–531. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Hartley CE, Varma M, Fischer JP, Riccardi
R, Strauss JA, Shah S, Zhang S and Yang ZJ: Neuroprotective effects
of erythropoietin on acute metabolic and pathological changes in
experimentally induced neurotrauma. J Neurosurg. 109:708–714. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Agnello D, Bigini P, Villa P, Mennini T,
Cerami A, Brines ML and Ghezzi P: Erythropoietin exerts an
anti-inflammatory effect on the CNS in a model of experimental
autoimmune encephalomyelitis. Brain Res. 952:128–134. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Chong ZZ, Kang JQ and Maiese K:
Erythropoietin fosters both intrinsic and extrinsic neuronal
protection through modulation of microglia, Akt1, Bad, and
caspase-mediated pathways. Br J Pharmacol. 138:1107–1118. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chen G, Shi JX, Hang CH, Xie W, Liu J and
Liu X: Inhibitory effect on cerebral inflammatory agents that
accompany traumatic brain injury in a rat model: a potential
neuroprotective mechanism of recombinant human erythropoietin
(rhEPO). Neurosci Lett. 425:177–182. 2007. View Article : Google Scholar
|
|
21
|
Digicaylioglu M and Lipton SA:
Erythropoietin-mediated neuro-protection involves cross-talk
between Jak2 and NF-kappaB signalling cascades. Nature.
412:641–647. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
22
|
Chong ZZ, Kang JQ and Maiese K: Essential
cellular regulatory elements of oxidative stress in early and late
phases of apoptosis in the central nervous system. Antioxid Redox
Signal. 6:277–287. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Xiong Y, Mahmood A, Qu C, Kazmi H, Zhang
ZG, Noguchi CT, Schallert T and Chopp M: Erythropoietin improves
histological and functional outcomes after traumatic brain injury
in mice in the absence of the neural erythropoietin receptor. J
Neurotrauma. 27:205–215. 2010. View Article : Google Scholar
|
|
24
|
Gourmala NG, Buttini M, Limonta S, Sauter
A and Boddeke HW: Differential and time-dependent expression of
monocyte chemoattractant protein-1 mRNA by astrocytes and
macrophages in rat brain: effects of ischemia and peripheral
lipopolysaccharide administration. J Neuroimmunol. 74:35–44. 1997.
View Article : Google Scholar
|
|
25
|
Xiong Y, Lu D, Qu C, Goussev A, Schallert
T, Mahmood A and Chopp M: Effects of erythropoietin on reducing
brain damage and improving functional outcome after traumatic brain
injury in mice. J Neurosurg. 109:510–521. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Chong ZZ, Kang JQ and Maiese K:
Erythropoietin is a novel vascular protectant through activation of
Akt1 and mitochondrial modulation of cysteine proteases.
Circulation. 106:2973–2979. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Martínez-Estrada OM, Rodríguez-Millán E,
González-De Vicente E, Reina M, Vilaró S and Fabre M:
Erythropoietin protects the in vitro blood-brain barrier against
VEGF-induced permeability. Eur J Neurosci. 18:2538–2544.
2003.PubMed/NCBI
|
