Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
May 2013 Volume 5 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May 2013 Volume 5 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis

  • Authors:
    • Zong-Huan Li
    • Ai-Xi Yu
    • Xiao-Peng Guo
    • Bai-Wen Qi
    • Min Zhou
    • Wei-Yang Wang
  • View Affiliations / Copyright

    Affiliations: Department of Micro-Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China
  • Pages: 1531-1537
    |
    Published online on: March 19, 2013
       https://doi.org/10.3892/etm.2013.1017
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

This meta-analysis was performed to evaluate the efficiency and the safety of absorbable implants. Five major electronic databases (PubMed, Embase, Cochrane Library, SinoMed and Wanfang Data) were systematically searched for randomized controlled trials (RCTs) from their establishment to November 2012. Studies on absorbable implants and metal implants for ankle fractures were selected. The meta‑analysis was performed using RevMan 5.1. Ten studies with 762 patients were included and analyzed. Compared with metal implants, absorbable implants used for the internal fixation of ankle fractures produce similar radiographic and functional outcomes (P=0.52). Normally, removal of the internal fixation is unnecessary (P<0.0001) and the incidence of palpable implants is lower (P=0.02) for absorbable implants. No statistically significant difference was observed between the two groups with regard to foreign body reactions (P=0.07), infection (P=0.69), osteoarthritis (P=0.39), pain (P=0.06), refracture (P=0.67), skin necrosis (P=0.99), deep vein thrombosis (P=0.21) and nerve injury (P=0.94). Absorbable implants used in ankle fractures rarely require reoperation and result in similar functional outcomes and complications compared with metal implants. These characteristics make them efficient and reasonably safe for the treatment of ankle fractures.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

View References

1. 

Court-Brown CM and Caesar B: Epidemiology of adult fractures: A review. Injury. 37:691–697. 2006. View Article : Google Scholar : PubMed/NCBI

2. 

Scott AM: Diagnosis and treatment of ankle fractures. Radiol Technol. 81:457–475. 2010.

3. 

Ganesh SP, Pietrobon R, Cecilio WA, Pan D, Lightdale N and Nunley JA: The impact of diabetes on patient outcomes after ankle fracture. J Bone Joint Surg Am. 87:1712–1718. 2005. View Article : Google Scholar : PubMed/NCBI

4. 

Hopton BP and Harris NJ: Fractures of the foot and ankle. Surgery (Oxford). 28:502–507. 2010. View Article : Google Scholar

5. 

Böstman O, Hirvensalo E, Vainionpää S, Mäkelä A, Vihtonen K, Törmälä P and Rokkanen P: Ankle fractures treated using biodegradable internal fixation. Clin Orthop Relat Res. 195–203. 1989.PubMed/NCBI

6. 

Gaweda K, Walawski J, Weglowski R and Krzyzanowski W: Comparison of bioabsorbable interference screws and posts for distal fixation in anterior cruciate ligament reconstruction. Int Orthop. 33:123–127. 2009. View Article : Google Scholar : PubMed/NCBI

7. 

Zhang J, Xiao B and Wu Z: Surgical treatment of calcaneal fractures with bioabsorbable screws. Int Orthop. 35:529–533. 2011. View Article : Google Scholar : PubMed/NCBI

8. 

Rokkanen PU, Böstman O, Hirvensalo E, et al: Bioabsorbable fixation in orthopaedic surgery and traumatology. Biomaterials. 21:2607–2613. 2000. View Article : Google Scholar : PubMed/NCBI

9. 

Olerud C and Molander H: A scoring scale for symptom evaluation after ankle fracture. Arch Orthop Trauma Surg. 103:190–194. 1984. View Article : Google Scholar : PubMed/NCBI

10. 

Jiang N, Wang B, Chen A, Dong F and Yu B: Operative versus nonoperative treatment for acute Achilles tendon rupture: a meta-analysis based on current evidence. Int Orthop. 36:765–773. 2012. View Article : Google Scholar

11. 

Jung HN, Roh YH, Yang BG, Kim SW, Lee JS and Oh MK: Outcomes of operative treatment of unstable ankle fractures: a comparison of metallic and biodegradable implants. J Bone Joint Surg Am. 94:e1662012.PubMed/NCBI

12. 

Song ZL: The choice of fixators for surgery of trimalleolar fractures. Chinese Journal of Primary Medicine and Pharmacy. 18:2935–2936. 2011.(In Chinese).

13. 

Shi WY, Huang JJ and Huang L: Clinical efficiency of absorbable screws for the treatment of internal malleolus fractures. Journal of Minimally Invasive Medicine. 6:139–140. 2011.(In Chinese).

14. 

Yun C, Zhu JH, He JS and Yang T: Treating ankle joint fracture by simplified surgical techniques. Journal of Clinical Orthopaedics. 11:269–270. 2008.(In Chinese).

15. 

Springer MA, van Binsbergen EA, Patka P, Bakker FC and Haarman HJ: Resorbable rods and screws for fixation of ankle fractures. A randomized clinical prospective study. Unfallchirurg. 101:377–381. 1998.(In German).

16. 

Kankare J, Partio EK, Hirvensalo E, Böstman O and Rokkanen P: Biodegradable self-reinforced polyglycolide screws and rods in the fixation of displaced malleolar fractures in the elderly: A comparison with metallic implants. Ann Chir Gynaecol. 85:263–270. 1996.PubMed/NCBI

17. 

Kankare J, Hirvensalo E and Rokkanen P: Malleolar fractures in alcoholics treated with biodegradable internal fixation: 6/16 reoperations in a randomized study. Acta Orthop Scand. 66:524–528. 1995. View Article : Google Scholar : PubMed/NCBI

18. 

Bucholz RW, Henry S and Henley MB: Fixation with bioabsorbable screws for the treatment of fractures of the ankle. J Bone Joint Surg Am. 76:319–324. 1994.PubMed/NCBI

19. 

Dijkema AR, van der Elst M, Breederveld RS, Verspui G, Patka P and Haarman HJ: Surgical treatment of fracture-dislocations of the ankle joint with biodegradable implants: a prospective randomized study. J Trauma. 34:82–84. 1993. View Article : Google Scholar : PubMed/NCBI

20. 

Böstman O, Vainionpää S, Hirvensalo E, Mäkelä A, Vihtonen K, Törmälä P and Rokkanen P: Biodegradable internal fixation for malleolar fractures: A prospective randomised trial. J Bone Joint Surg Br. 69:615–619. 1987.PubMed/NCBI

21. 

Westerman RW and Porter K: Ankle fractures in adults: an overview. Trauma. 9:267–272. 2007. View Article : Google Scholar

22. 

Rangdal S, Singh D, Joshi N, Soni A and Sament R: Functional outcome of ankle fracture patients treated with biodegradable implants. Foot Ankle Surg. 18:153–156. 2012. View Article : Google Scholar : PubMed/NCBI

23. 

Pina S and Ferreira JMF: Bioresorbable plates and screws for clinical applications: a review. J Healthc Eng. 3:243–260. 2012. View Article : Google Scholar

24. 

Spitalny AD: Bioabsorbable implants. Clin Podiatr Med Surg. 23:673–694. 2006. View Article : Google Scholar : PubMed/NCBI

25. 

Stroud CC: Absorbable implants in fracture management. Foot Ankle Clin. 7:495–499. 2002. View Article : Google Scholar : PubMed/NCBI

26. 

Böstman OM: Osteoarthritis of the ankle after foreign-body reaction to absorbable pins and screws: a three- to nine-year follow-up study. J Bone Joint Surg Br. 80:333–338. 1998.PubMed/NCBI

27. 

Givissis PK, Stavridis SI, Papagelopoulos PJ, Antonarakos PD and Christodoulou AG: Delayed foreign-body reaction to absorbable implants in metacarpal fracture treatment. Clin Orthop Relat Res. 468:3377–3383. 2010. View Article : Google Scholar : PubMed/NCBI

28. 

Pihlajamäki HK, Salminen ST, Tynninen O, Böstman OM and Laitinen O: Tissue restoration after implantation of polyglycolide, polydioxanone, polylevolactide, and metallic pins in cortical bone: an experimental study in rabbits. Calcif Tissue Int. 87:90–98. 2010.PubMed/NCBI

29. 

Sinisaari I, Pätiälä H, Böstman O, et al: Metallic or absorbable implants for ankle fractures: a comparative study of infections in 3,111 cases. Acta Orthop Scand. 67:16–18. 1996. View Article : Google Scholar : PubMed/NCBI

30. 

Lübbeke A, Salvo D, Stern R, Hoffmeyer P, Holzer N and Assal M: Risk factors for post-traumatic osteoarthritis of the ankle: an eighteen year follow-up study. Int Orthop. 36:1403–1410. 2012.PubMed/NCBI

31. 

Böstman OM and Pihlajamäki HK: Adverse tissue reactions to bioabsorbable fixation devices. Clin Orthop Relat Res. 216–227. 2000.PubMed/NCBI

32. 

Horisberger M, Valderrabano V and Hintermann B: Posttraumatic ankle osteoarthritis after ankle-related fractures. J Orthop Trauma. 23:60–67. 2009. View Article : Google Scholar : PubMed/NCBI

33. 

Nourbakhsh A, Patil S, Vannemreddy P, Ogden A, Mukherjee D and Nanda A: The use of bioabsorbable screws to fix type II odontoid fractures: a biomechanical study. J Neurosurg Spine. 15:361–366. 2011. View Article : Google Scholar : PubMed/NCBI

34. 

Buijs GJ, van Bakelen NB, Jansma J, et al: A randomized clinical trial of biodegradable and titanium fixation systems in maxillofacial surgery. J Dent Res. 91:299–304. 2012. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Li Z, Yu A, Guo X, Qi B, Zhou M and Wang W: Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis. Exp Ther Med 5: 1531-1537, 2013.
APA
Li, Z., Yu, A., Guo, X., Qi, B., Zhou, M., & Wang, W. (2013). Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis. Experimental and Therapeutic Medicine, 5, 1531-1537. https://doi.org/10.3892/etm.2013.1017
MLA
Li, Z., Yu, A., Guo, X., Qi, B., Zhou, M., Wang, W."Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis". Experimental and Therapeutic Medicine 5.5 (2013): 1531-1537.
Chicago
Li, Z., Yu, A., Guo, X., Qi, B., Zhou, M., Wang, W."Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis". Experimental and Therapeutic Medicine 5, no. 5 (2013): 1531-1537. https://doi.org/10.3892/etm.2013.1017
Copy and paste a formatted citation
x
Spandidos Publications style
Li Z, Yu A, Guo X, Qi B, Zhou M and Wang W: Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis. Exp Ther Med 5: 1531-1537, 2013.
APA
Li, Z., Yu, A., Guo, X., Qi, B., Zhou, M., & Wang, W. (2013). Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis. Experimental and Therapeutic Medicine, 5, 1531-1537. https://doi.org/10.3892/etm.2013.1017
MLA
Li, Z., Yu, A., Guo, X., Qi, B., Zhou, M., Wang, W."Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis". Experimental and Therapeutic Medicine 5.5 (2013): 1531-1537.
Chicago
Li, Z., Yu, A., Guo, X., Qi, B., Zhou, M., Wang, W."Absorbable implants versus metal implants for the treatment of ankle fractures: A meta-analysis". Experimental and Therapeutic Medicine 5, no. 5 (2013): 1531-1537. https://doi.org/10.3892/etm.2013.1017
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team