Intramuscular schwannoma of the musculocutaneous nerve: An uncommon clinical presentation

Nishio,Jun; Ueki,Takayuki; Naito,Masatoshi

doi:10.3892/etm.2013.1084

July 2013 Volume 6 Issue 1

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July 2013 Volume 6 Issue 1

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Article

Intramuscular schwannoma of the musculocutaneous nerve: An uncommon clinical presentation

Authors:
- Jun Nishio
- Takayuki Ueki
- Masatoshi Naito
View Affiliations / Copyright

Affiliations: Department of Orthopaedic Surgery, Faculty of Medicine, Fukuoka University, Fukuoka 814-0180, Japan
Pages: 164-166
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Published online on: April 29, 2013

https://doi.org/10.3892/etm.2013.1084
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Abstract

A schwannoma is a benign peripheral nerve sheath tumor composed exclusively of Schwann cells. A major-nerve schwannoma with an intramuscular location is an extremely rare condition. We present a rare case of intramuscular schwannoma originating from the musculocutaneous nerve in a 71-year-old female. The patient presented with a 7-month history of a slowly growing, painless mass in the medial aspect of the proximal upper arm. Magnetic resonance imaging revealed an oval-shaped intramuscular soft tissue mass with iso-signal intensity relative to skeletal muscle on T1-weighted images and high signal intensity on T2-weighted images. A rim of fat surrounding the mass, suggesting the split-fat sign, was also observed. The tumor was completely enucleated using an intracapsular technique. Histological examination confirmed the diagnosis of schwannoma consisting of Antoni A and B areas. There was no immediate neurological deficit following surgery. The patient had no evidence of local recurrence and no neurological deficit at final follow-up. To the best of our knowledge, this is the first report of musculocutaneous nerve schwannoma within the coracobrachialis muscle.

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1.	Kwon BC, Baek GH, Chung MS, Lee SH, Kim HS and Oh JH: Intramuscular neurilemoma. J Bone Joint Surg Br. 85:723–725. 2003.
2.	Shimose S, Sugita T, Kubo T, Matsuo T, Nobuto H, Tanaka K, Arihiro K and Ochi M: Major-nerve schwannomas versus intramuscular schwannomas. Acta Radiol. 48:672–677. 2007. View Article : Google Scholar : PubMed/NCBI
3.	Osborne AW, Birch RM, Munshi P and Bonney G: The musculo-cutaneous nerve. J Bone Joint Surg Br. 82:1140–1142. 2000. View Article : Google Scholar
4.	Tagliafico AS, Michaud J, Marchetti A, Garello I, Padua L and Martinoli C: US imaging of the musculocutaneous nerve. Skeletal Radiol. 40:609–616. 2011. View Article : Google Scholar : PubMed/NCBI
5.	Knight DM, Birch R and Pringle J: Benign solitary schwannomas: a review of 234 cases. J Bone Joint Surg Br. 89:382–387. 2007. View Article : Google Scholar : PubMed/NCBI
6.	Rodriguez FJ, Folpe AL, Giannini C and Perry A: Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems. Acta Neuropathol. 123:295–319. 2012. View Article : Google Scholar : PubMed/NCBI
7.	Donner TR, Voorhies RM and Kline DG: Neural sheath tumors of major nerves. J Neurosurg. 81:362–373. 1994. View Article : Google Scholar : PubMed/NCBI
8.	Park MJ, Seo KN and Kang HJ: Neurological deficit after surgical enucleation of schwannomas of the upper limb. J Bone Joint Surg Br. 91:1482–1486. 2009. View Article : Google Scholar : PubMed/NCBI
9.	Date R, Muramatsu K, Ihara K and Taguchi T: Advantages of intra-capsular micro-enucleation of schwannoma arising from extremities. Acta Neurochir (Wien). 154:173–178. 2012. View Article : Google Scholar : PubMed/NCBI
10.	Kim SM, Seo SW, Lee JY and Sung KS: Surgical outcome of Schwannomas arising from major peripheral nerves in the lower limb. Int Orthop. 36:1721–1725. 2012. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Intramuscular schwannoma of the musculocutaneous nerve: An uncommon clinical presentation

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