The effect of electroacupuncture on postoperative immunoinflammatory response in patients undergoing supratentorial craniotomy

Li,Guoyan; Li,Shuqin; Wang,Baoguo; An,Lixin

doi:10.3892/etm.2013.1225

September 2013 Volume 6 Issue 3

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September 2013 Volume 6 Issue 3

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Article

The effect of electroacupuncture on postoperative immunoinflammatory response in patients undergoing supratentorial craniotomy

Authors:
- Guoyan Li
- Shuqin Li
- Baoguo Wang
- Lixin An
View Affiliations / Copyright

Affiliations: Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China, Department of Anesthesiology and Pain Management, Beijing Sanbo Brain Hospital, Capital Medical University, Beijing 100093, P.R. China
Pages: 699-702
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Published online on: July 16, 2013

https://doi.org/10.3892/etm.2013.1225
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Abstract

The aim of this study was to explore the effect of electroacupuncture (EA) on immune function in patients undergoing supratentorial craniotomy. We also examined whether point specificity in EA was present. The study involved 29 patients undergoing craniotomy. The patients were divided into three groups: a control (C, n=10), an EA (A, n=9) and a sham acupoints group (S, n=10). Blood samples were collected at the following time points: before anesthesia (T0), 4 h after the induction of anesthesia (T1), 1 day post-surgery (T2) and 2 days post-surgery (T3) to determine the levels of tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8), interleukin-10 (IL-10), immunoglobulin M (IgM), IgA and IgG. Data were analyzed using SPSS 13.0 software. When comparing the levels of cytokines following surgery, we observed that the peripheral blood IL-8 levels in groups A and S were increased significantly compared with those of group C at 1 and 2 days after surgery. When comparing immunoglobulin levels after surgery, we established that the peripheral blood IgA levels in group C had decreased significantly compared to those of group A and group S 4 h after induction of anesthesia and 1 day after surgery. However, there was no significant difference between group A and group S. Compared with simple general anesthesia, acupuncture combined with anesthesia partially reduces immune suppression in the perioperative periods under the same conditions as the simple general anesthesia. Point specificity in EA was not present.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

The effect of electroacupuncture on postoperative immunoinflammatory response in patients undergoing supratentorial craniotomy

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Abstract

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