A case of veno‑occlusive disease following liver transplantation

Chen,Hong; Wang,Xu; Fan,Tieyan; Li,Jun; Wang,Letian; Shen,Zhongyang

doi:10.3892/etm.2013.1401

2014-January Volume 7 Issue 1

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2014-January Volume 7 Issue 1

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Article

A case of veno‑occlusive disease following liver transplantation

Authors:
- Hong Chen
- Xu Wang
- Tieyan Fan
- Jun Li
- Letian Wang
- Zhongyang Shen
View Affiliations / Copyright

Affiliations: Institute of Organ Transplantation, The General Hospital of Chinese People's Armed Police Forces, Beijing 100039, P.R. China
Pages: 141-144
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Published online on: November 11, 2013

https://doi.org/10.3892/etm.2013.1401
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Abstract

The present case report describes the diagnosis and treatment of a patient with veno‑occlusive disease (VOD) following liver transplantation. Combining the clinical data and relevant literature, the study aimed to consider the causes of VOD following liver transplantation, and the pathogenesis, clinical diagnosis and auxiliary examination features of VOD. A 42‑year‑old man who had a long history of taking traditional Chinese medicine (essential components unknown) underwent an orthotropic liver transplantation on January 14, 2011, due to small venous occlusion disease of the liver. The patient was treated with tacrolimus as an antirejection therapy following the surgery, and gradually developed right upper quadrant pain and fatigue. The examination results were consistent with the diagnostic standards for VOD. Following treatment with methylprednisolone, the patient was treated with alprostadil and Danhong injections. Forty days later, the patient's total bilirubin (TBIL) level was observed to have decreased significantly, the liver function had returned to normal and the ascites had decreased, but had not completely disappeared. The patient then underwent a transjugular intrahepatic portosystemic shunt (TIPS) procedure, following which the ascites were shown to have completely disappeared.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

A case of veno‑occlusive disease following liver transplantation

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