A case of veno‑occlusive disease following liver transplantation

  • Authors:
    • Hong Chen
    • Xu Wang
    • Tieyan Fan
    • Jun Li
    • Letian Wang
    • Zhongyang Shen
  • View Affiliations

  • Published online on: November 11, 2013     https://doi.org/10.3892/etm.2013.1401
  • Pages: 141-144
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Abstract

The present case report describes the diagnosis and treatment of a patient with veno‑occlusive disease (VOD) following liver transplantation. Combining the clinical data and relevant literature, the study aimed to consider the causes of VOD following liver transplantation, and the pathogenesis, clinical diagnosis and auxiliary examination features of VOD. A 42‑year‑old man who had a long history of taking traditional Chinese medicine (essential components unknown) underwent an orthotropic liver transplantation on January 14, 2011, due to small venous occlusion disease of the liver. The patient was treated with tacrolimus as an antirejection therapy following the surgery, and gradually developed right upper quadrant pain and fatigue. The examination results were consistent with the diagnostic standards for VOD. Following treatment with methylprednisolone, the patient was treated with alprostadil and Danhong injections. Forty days later, the patient's total bilirubin (TBIL) level was observed to have decreased significantly, the liver function had returned to normal and the ascites had decreased, but had not completely disappeared. The patient then underwent a transjugular intrahepatic portosystemic shunt (TIPS) procedure, following which the ascites were shown to have completely disappeared.
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2014-January
Volume 7 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Chen H, Wang X, Fan T, Li J, Wang L and Shen Z: A case of veno‑occlusive disease following liver transplantation. Exp Ther Med 7: 141-144, 2014
APA
Chen, H., Wang, X., Fan, T., Li, J., Wang, L., & Shen, Z. (2014). A case of veno‑occlusive disease following liver transplantation. Experimental and Therapeutic Medicine, 7, 141-144. https://doi.org/10.3892/etm.2013.1401
MLA
Chen, H., Wang, X., Fan, T., Li, J., Wang, L., Shen, Z."A case of veno‑occlusive disease following liver transplantation". Experimental and Therapeutic Medicine 7.1 (2014): 141-144.
Chicago
Chen, H., Wang, X., Fan, T., Li, J., Wang, L., Shen, Z."A case of veno‑occlusive disease following liver transplantation". Experimental and Therapeutic Medicine 7, no. 1 (2014): 141-144. https://doi.org/10.3892/etm.2013.1401