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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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2014-January Volume 7 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report

Intractable epilepsy due to angiocentric glioma: A case report and minireview

  • Authors:
    • Guoqiang Chen
    • Lin Wang
    • Jinting Wu
    • Yongjian Jin
    • Xiaosong Wang
    • Yulan Jin
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China, Department of Neurosurgery, Yuquan Hospital, Tsinghua University, Beijing 100049, P.R. China, Department of Pathology, Tongren Hospital, Capital Medical University, Beijing 100730, P.R. China
  • Pages: 61-65
    |
    Published online on: November 11, 2013
       https://doi.org/10.3892/etm.2013.1402
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Abstract

The aim of this case report and minireview was to investigate the diagnosis of and therapeutic approaches for angiocentric glioma (AG) and to summarize the clinical manifestations and the pathological and imaging characteristics of the disease. Intraoperative cortical electroencephalogram (ECoG) monitoring was performed to locate the epileptic foci in a child with AG who presented with intractable epilepsy, prior to the total resection of the tumor being performed under the microscope. The clinical features, imaging characteristics, intraoperative conditions, surgical methods and pathological results were analyzed and compared with the literature. The review revealed that to date, the clinical features of the 52 reported cases of AG (including this case) have been mainly characterized by epilepsy. High T2‑weighted image (WI) and fluid‑attenuated inversion recovery (FLAIR) signals may be detected with magnetic resonance imaging (MRI) scanning of the cranium; however, no enhancement signals are detected by enhanced scanning. The prognosis following surgical resection is favorable. The lesions in the present case demonstrated clear boundaries with a central cystic affection accompanied by an arachnoid cyst on the left temporal pole. Pathological examination revealed that the lesion was positive for glial fibrillary acidic protein (GFAP), S‑100 protein, vimentin, epithelial membrane antigen (EMA), cluster of differentiation 99 (CD99) and D2‑40. The Ki‑67/MIBk‑1 labeling index was ~1%. In conclusion, AG exhibits characteristic features in imaging; however, its diagnosis depends on histopathological examination. The prognosis of total surgical resection is good and intraoperative ECoG may be used to assist positioning.
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Copy and paste a formatted citation
Spandidos Publications style
Chen G, Wang L, Wu J, Jin Y, Wang X and Jin Y: Intractable epilepsy due to angiocentric glioma: A case report and minireview. Exp Ther Med 7: 61-65, 2014.
APA
Chen, G., Wang, L., Wu, J., Jin, Y., Wang, X., & Jin, Y. (2014). Intractable epilepsy due to angiocentric glioma: A case report and minireview. Experimental and Therapeutic Medicine, 7, 61-65. https://doi.org/10.3892/etm.2013.1402
MLA
Chen, G., Wang, L., Wu, J., Jin, Y., Wang, X., Jin, Y."Intractable epilepsy due to angiocentric glioma: A case report and minireview". Experimental and Therapeutic Medicine 7.1 (2014): 61-65.
Chicago
Chen, G., Wang, L., Wu, J., Jin, Y., Wang, X., Jin, Y."Intractable epilepsy due to angiocentric glioma: A case report and minireview". Experimental and Therapeutic Medicine 7, no. 1 (2014): 61-65. https://doi.org/10.3892/etm.2013.1402
Copy and paste a formatted citation
x
Spandidos Publications style
Chen G, Wang L, Wu J, Jin Y, Wang X and Jin Y: Intractable epilepsy due to angiocentric glioma: A case report and minireview. Exp Ther Med 7: 61-65, 2014.
APA
Chen, G., Wang, L., Wu, J., Jin, Y., Wang, X., & Jin, Y. (2014). Intractable epilepsy due to angiocentric glioma: A case report and minireview. Experimental and Therapeutic Medicine, 7, 61-65. https://doi.org/10.3892/etm.2013.1402
MLA
Chen, G., Wang, L., Wu, J., Jin, Y., Wang, X., Jin, Y."Intractable epilepsy due to angiocentric glioma: A case report and minireview". Experimental and Therapeutic Medicine 7.1 (2014): 61-65.
Chicago
Chen, G., Wang, L., Wu, J., Jin, Y., Wang, X., Jin, Y."Intractable epilepsy due to angiocentric glioma: A case report and minireview". Experimental and Therapeutic Medicine 7, no. 1 (2014): 61-65. https://doi.org/10.3892/etm.2013.1402
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