Splenic metastasis of ovarian clear cell adenocarcinoma: A case report and review of the literature

  • Authors:
    • Meiling Lv
    • Yuyao Li
    • Changqin Luo
    • Peijun Liu
    • Jin Yang
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  • Published online on: January 24, 2014     https://doi.org/10.3892/etm.2014.1500
  • Pages: 982-986
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Abstract

Splenic metastasis of ovarian cancer appears to be more common in serous cystadenocarcinomas. Splenic metastasis usually occurs postoperatively and simultaneously with dissemination to the greater omentum and pelvic cavity. Compared with other ovarian cancer subtypes, ovarian clear cell adenocarcinoma (OCCA) is rare, accounting for <5% of all ovarian malignancies. OCCA has a distinct histological type with poor prognosis and resistance to platinum-based chemotherapy. In the present study, a case of isolated splenic metastasis of OCCA was reported. A 53-year-old female presented with a mass in the left upper quadrant without any other clinical manifestations. Subsequent abdominal and pelvic computed tomography scans revealed multiple mixed cystic-solid lesions, potentially predicting ovarian malignancy. Pathological tests following ovarian cytoreductive surgery revealed primary OCCA with metastases to the spleen. The current study also reviewed recently published literature on splenic metastasis of ovarian carcinoma and demonstrated that the reported case was a rare case of isolated splenic metastasis of OCCA.
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2014-April
Volume 7 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Lv M, Li Y, Luo C, Liu P and Yang J: Splenic metastasis of ovarian clear cell adenocarcinoma: A case report and review of the literature. Exp Ther Med 7: 982-986, 2014
APA
Lv, M., Li, Y., Luo, C., Liu, P., & Yang, J. (2014). Splenic metastasis of ovarian clear cell adenocarcinoma: A case report and review of the literature. Experimental and Therapeutic Medicine, 7, 982-986. https://doi.org/10.3892/etm.2014.1500
MLA
Lv, M., Li, Y., Luo, C., Liu, P., Yang, J."Splenic metastasis of ovarian clear cell adenocarcinoma: A case report and review of the literature". Experimental and Therapeutic Medicine 7.4 (2014): 982-986.
Chicago
Lv, M., Li, Y., Luo, C., Liu, P., Yang, J."Splenic metastasis of ovarian clear cell adenocarcinoma: A case report and review of the literature". Experimental and Therapeutic Medicine 7, no. 4 (2014): 982-986. https://doi.org/10.3892/etm.2014.1500