Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects

Lu,Chengwen; Song,Yanqin; Zhang,Jianqiao; Du,Yuan; Wang,Tian; Xue,Yunli; Fu,Fenghua; Zhang,Leiming

doi:10.3892/etm.2014.1524

2014-April Volume 7 Issue 4

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2014-April Volume 7 Issue 4

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Article

Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects

Authors:
- Chengwen Lu
- Yanqin Song
- Jianqiao Zhang
- Yuan Du
- Tian Wang
- Yunli Xue
- Fenghua Fu
- Leiming Zhang
View Affiliations / Copyright

Affiliations: Department of Pharmacology, School of Pharmacy, Yantai University, Yantai, Shandong 264005, P.R. China, Shandong Luye Pharmaceutical Company, Ltd., Yantai, Shandong 264003, P.R. China
Pages: 990-994
|
Published online on: February 6, 2014

https://doi.org/10.3892/etm.2014.1524
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Abstract

Chronic pharyngitis is chronic inflammation that is often caused by repeated occurrences of acute pharyngitis or upper respiratory tract infections, including Streptococcus and Staphylococcus. The present study aimed to investigate the effects of Yanshu spraying agent (Yanshu) in relieving chronic pharyngitis, as well as the possible underlying mechanisms. The results revealed that Yanshu inhibited chronic inflammation in ammonia‑induced chronic pharyngitis in rabbits and cotton pellet-induced granuloma tissue formation in rats. Yanshu also demonstrated antibacterial effects on Streptococcus and Staphylococcus in vitro. Yanshu did not exhibit any effects on the immune system, including the spleen and thymus indexes, immunocyte count and monocyte-macrophage function, when compared with the effects of dexamethasone. Therefore, the results of the present study indicate that Yanshu may relieve chronic pharyngitis via its anti-inflammatory and antibacterial activities.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Yanshu spraying agent, a traditional Chinese medicine, relieves chronic pharyngitis in animals by anti-inflammatory and antibacterial effects

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