Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis

  • Authors:
    • Zhi-Hua Liu
    • Chao Li
    • Xing-Wei Zhang
    • Liang Kang
    • Jian-Ping Wang
  • View Affiliations

  • Published online on: February 25, 2014     https://doi.org/10.3892/etm.2014.1584
  • Pages: 1181-1186
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Abstract

Appendicectomy has been the gold standard treatment of acute appendicitis for more than a century, while nonoperative therapies, including antibiotics, have acquired increased interest in recent years. The present meta‑analysis aimed to compare the therapeutic effects of antibiotics versus appendicectomy for the treatment of acute appendicitis. Medline, Embase and The Cochrane Library databases were searched. Prospective randomized controlled trials that compared antibiotic treatment with surgery were included. The outcomes evaluated included the time of hospital stay, complications and time to work. There were no statistically significant differences between the antibiotic and appendicectomy groups with regard to the time of hospital stay and complications. However, the time to work was significantly longer in the appendicectomy group when compared with the antibiotic group. In addition, the therapeutic effects of antibiotics and appendicectomy were comparable for the treatment of acute appendicitis.
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May-2014
Volume 7 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Liu Z, Li C, Zhang X, Kang L and Wang J: Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis. Exp Ther Med 7: 1181-1186, 2014
APA
Liu, Z., Li, C., Zhang, X., Kang, L., & Wang, J. (2014). Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis. Experimental and Therapeutic Medicine, 7, 1181-1186. https://doi.org/10.3892/etm.2014.1584
MLA
Liu, Z., Li, C., Zhang, X., Kang, L., Wang, J."Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis". Experimental and Therapeutic Medicine 7.5 (2014): 1181-1186.
Chicago
Liu, Z., Li, C., Zhang, X., Kang, L., Wang, J."Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis". Experimental and Therapeutic Medicine 7, no. 5 (2014): 1181-1186. https://doi.org/10.3892/etm.2014.1584