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Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two‑dimensional tissue motion annular displacement

  • Authors:
    • Liwen Liu
    • Shengjun Tuo
    • Jianlei Zhang
    • Lei Zuo
    • Fang Liu
    • Lili Hao
    • Yandan Sun
    • Liping Yang
    • Hong Shao
    • Wei Qi
    • Xiaodong Zhou
    • Shuping Ge
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasound, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China, Department of Cardiology, The Heart Center, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, PA 19134, USA
  • Pages: 1457-1464
    |
    Published online on: March 12, 2014
       https://doi.org/10.3892/etm.2014.1617
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Abstract

The early detection of abnormal left ventricular systolic functions in patients with hypertrophic cardiomyopathy (HCM) remains a challenge. The aim of this study was to identify a novel method for the assessment of left ventricular systolic function in patients with HCM. A total of 65 patients with HCM were included in this study. The patients were divided into obstructive HCM (HOCM; 16 cases) and non‑obstructive HCM (NOHCM; 49 cases) groups. The healthy control group comprised 48 participants. Two‑dimensional (2D) speckle‑tracking technology was used to measure the left ventricular global and segmental longitudinal strains and mitral annular displacement (MADs). Compared with healthy control group, the six segmental strains and the global strain of the left ventricle (LSglobal) increased while six segmental MADs and MADglobal of the mitral annulus decreased in the HOCM and NOHCM groups (P<0.05). In addition, the six segmental MADs of the mitral annulus were significantly negatively correlated with the six segmental strains of the left ventricle (r=‑0.744 to ‑0.647, P<0.001). MADglobal was significantly negatively correlated with LSglobal (r=‑0.857, P<0.001). The tissue motion annular displacement (TMAD) at the midpoint was significantly negatively correlated with LSglobal (r=‑0.871, P<0.001). The 2D TMAD technique of measuring MAD was feasible and practically approachable for rapidly evaluating the left ventricular longitudinal global and segmental systolic functions of patients with HCM.
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Copy and paste a formatted citation
Spandidos Publications style
Liu L, Tuo S, Zhang J, Zuo L, Liu F, Hao L, Sun Y, Yang L, Shao H, Qi W, Qi W, et al: Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two‑dimensional tissue motion annular displacement. Exp Ther Med 7: 1457-1464, 2014.
APA
Liu, L., Tuo, S., Zhang, J., Zuo, L., Liu, F., Hao, L. ... Ge, S. (2014). Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two‑dimensional tissue motion annular displacement. Experimental and Therapeutic Medicine, 7, 1457-1464. https://doi.org/10.3892/etm.2014.1617
MLA
Liu, L., Tuo, S., Zhang, J., Zuo, L., Liu, F., Hao, L., Sun, Y., Yang, L., Shao, H., Qi, W., Zhou, X., Ge, S."Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two‑dimensional tissue motion annular displacement". Experimental and Therapeutic Medicine 7.6 (2014): 1457-1464.
Chicago
Liu, L., Tuo, S., Zhang, J., Zuo, L., Liu, F., Hao, L., Sun, Y., Yang, L., Shao, H., Qi, W., Zhou, X., Ge, S."Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two‑dimensional tissue motion annular displacement". Experimental and Therapeutic Medicine 7, no. 6 (2014): 1457-1464. https://doi.org/10.3892/etm.2014.1617
Copy and paste a formatted citation
x
Spandidos Publications style
Liu L, Tuo S, Zhang J, Zuo L, Liu F, Hao L, Sun Y, Yang L, Shao H, Qi W, Qi W, et al: Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two‑dimensional tissue motion annular displacement. Exp Ther Med 7: 1457-1464, 2014.
APA
Liu, L., Tuo, S., Zhang, J., Zuo, L., Liu, F., Hao, L. ... Ge, S. (2014). Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two‑dimensional tissue motion annular displacement. Experimental and Therapeutic Medicine, 7, 1457-1464. https://doi.org/10.3892/etm.2014.1617
MLA
Liu, L., Tuo, S., Zhang, J., Zuo, L., Liu, F., Hao, L., Sun, Y., Yang, L., Shao, H., Qi, W., Zhou, X., Ge, S."Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two‑dimensional tissue motion annular displacement". Experimental and Therapeutic Medicine 7.6 (2014): 1457-1464.
Chicago
Liu, L., Tuo, S., Zhang, J., Zuo, L., Liu, F., Hao, L., Sun, Y., Yang, L., Shao, H., Qi, W., Zhou, X., Ge, S."Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two‑dimensional tissue motion annular displacement". Experimental and Therapeutic Medicine 7, no. 6 (2014): 1457-1464. https://doi.org/10.3892/etm.2014.1617
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