Analysis of multiple factors involved in acute progressive cerebral infarction and extra‑ and intracranial arterial lesions

Chen,Yuefu; Liu,Yajie; Luo,Chenghong; Lu,Weiheng; Su,Binru

doi:10.3892/etm.2014.1624

June-2014 Volume 7 Issue 6

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June-2014 Volume 7 Issue 6

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Analysis of multiple factors involved in acute progressive cerebral infarction and extra‑ and intracranial arterial lesions

Authors:
- Yuefu Chen
- Yajie Liu
- Chenghong Luo
- Weiheng Lu
- Binru Su
View Affiliations / Copyright

Affiliations: Department of Neurology, Shilong People's Hospital, Southern Medical University, Dongguan, Guangdong 523326, P.R. China, Department of Neurology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China
Pages: 1495-1505
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Published online on: March 14, 2014

https://doi.org/10.3892/etm.2014.1624
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Abstract

In order to identify the potential factors involved in the development of acute progressive cerebral infarction (PCI), the association between potential risk factors and extra‑ and intracranial arterial lesions was investigated. A total of 608 patients underwent cerebral angiography to analyze the morphological characteristics between the PCI and NPCI groups. In addition, data from numerous cases of extra‑ and intracranial arterial lesions were collected and compared with the control groups, and the associations between the severity of arterial lesions and the potential influential factors were analyzed. In the blood vessels responsible for cerebral infarction, various degrees of atherosclerotic plaques and stenosis were observed. Age, high‑density lipoprotein (HDL) levels, glycosylated hemoglobin and blood pressure affected the degrees of hardening, plaques and stenosis. Analysis of cerebral artery stenosis revealed that age, diabetes mellitus and plasma fibrinogen were risk factors for cerebral artery stenosis, while the HDL/low density lipoprotein ratio was a protective factor. Therefore, the results of the present study indicate that the lesions of blood vessels are a major pathological change in PCI and multiple factors are involved in the pathogenesis.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Analysis of multiple factors involved in acute progressive cerebral infarction and extra‑ and intracranial arterial lesions

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