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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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October 2014 Volume 8 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report

Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review

  • Authors:
    • Lisheng Xu
    • Wei Xiao
    • Dedong Ma
    • Shengyu Zhou
    • Qinghui Zhang
  • View Affiliations / Copyright

    Affiliations: Departments of Respiratory Disease, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China, Department of Pathology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China
  • Pages: 1229-1236
    |
    Published online on: August 11, 2014
       https://doi.org/10.3892/etm.2014.1895
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Abstract

The aim of this study was to investigate the clinical features of ulcerative colitis (UC) combined with acute interstitial lung disease (ILD). One case with acute UC combined with ILD and airway disease was reported, and the pathological diagnosis of previous cases of UC combined with ILD was retrospectively analyzed according to the corresponding literature. The present case concerned a male patient with UC who presented with dry cough and progressive dyspnea. The chest computed tomography (CT) images showed as normal on the seventh day; diffuse ground‑glass shadows were observed on the 11th day and diffuse reticular, patchy, nodular shadows and lung cysts were observed on the 21st day. The results of an open lung biopsy on the 23rd day indicated pleural adhesions, and the pathologies were pulmonary fibrosis and airway inflammation. Glucocorticoid therapy was ineffective in the patient, but cyclophosphamide combined with γ globulin rapidly caused the disease to remit. A total of 24 cases with UC combined with ILD and two cases of UC combined with acute ILD were retrieved through PubMed. UC combined with acute ILD was rare in clinical practice. Patients with dry cough, progressive dyspnea and diffuse ground‑glass shadows in pulmonary CT images should be closely monitored. Glucocorticoid therapy should be carefully selected and precautions should be taken against opportunistic infections of the lung. Cyclophosphamide combined with γ globulin may be an effective treatment strategy.
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Copy and paste a formatted citation
Spandidos Publications style
Xu L, Xiao W, Ma D, Zhou S and Zhang Q: Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review. Exp Ther Med 8: 1229-1236, 2014.
APA
Xu, L., Xiao, W., Ma, D., Zhou, S., & Zhang, Q. (2014). Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review. Experimental and Therapeutic Medicine, 8, 1229-1236. https://doi.org/10.3892/etm.2014.1895
MLA
Xu, L., Xiao, W., Ma, D., Zhou, S., Zhang, Q."Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review". Experimental and Therapeutic Medicine 8.4 (2014): 1229-1236.
Chicago
Xu, L., Xiao, W., Ma, D., Zhou, S., Zhang, Q."Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review". Experimental and Therapeutic Medicine 8, no. 4 (2014): 1229-1236. https://doi.org/10.3892/etm.2014.1895
Copy and paste a formatted citation
x
Spandidos Publications style
Xu L, Xiao W, Ma D, Zhou S and Zhang Q: Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review. Exp Ther Med 8: 1229-1236, 2014.
APA
Xu, L., Xiao, W., Ma, D., Zhou, S., & Zhang, Q. (2014). Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review. Experimental and Therapeutic Medicine, 8, 1229-1236. https://doi.org/10.3892/etm.2014.1895
MLA
Xu, L., Xiao, W., Ma, D., Zhou, S., Zhang, Q."Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review". Experimental and Therapeutic Medicine 8.4 (2014): 1229-1236.
Chicago
Xu, L., Xiao, W., Ma, D., Zhou, S., Zhang, Q."Ulcerative colitis combined with acute interstitial lung disease and airway disease: A case report and literature review". Experimental and Therapeutic Medicine 8, no. 4 (2014): 1229-1236. https://doi.org/10.3892/etm.2014.1895
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