Retrospective evaluation of endoscopic stenting of combined malignant common bile duct and gastric outlet‑duodenum obstructions

Yu,Jianfeng; Hao,Jianyu; Wu,Dongfang; Lang,Haibo

doi:10.3892/etm.2014.1899

Retrospective evaluation of endoscopic stenting of combined malignant common bile duct and gastric outlet‑duodenum obstructions

Authors:
- Jianfeng Yu
- Jianyu Hao
- Dongfang Wu
- Haibo Lang
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Affiliations: Department of Gastroenterology, Beijing Chao‑Yang Hospital, Capital Medical University, Beijing 100020, P.R. China
Published online on: August 11, 2014 https://doi.org/10.3892/etm.2014.1899
Pages: 1173-1177

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Abstract

Malignant dual obstruction in the common bile duct and gastric outlet‑duodenum can cause difficulties in palliative treatment. The purpose of this study was to summarize our successful experience with the endoscopic stenting procedure for the palliative treatment of malignant biliary and gastric outlet‑duodenum obstruction. Seventeen patients who underwent dual stenting procedures for the common bile duct and duodenum were retrospectively reviewed. The success rate of placement, palliative effect for biliary and duodenal obstruction, incidence of complication and restricture and stent patency were analyzed. Stent placement achieved a 100% success rate. Total bilirubin decreased from 263.4±62.5 to 157.6±25.1 µmol/l, direct bilirubin decreased from 233.2±66.5 to 130.9±27.7 µmol/l and alkaline phosphatase from 534.2±78.7 to 216.3±23.3 IU/l. The differences between the preoperative and postoperative results were statistically significant (P<0.01). The gastric outlet obstruction score increased significantly from 0.9±1.1 to 2.1±0.7 points (P<0.01). The general nutritional status of the patients was improved. No serious complications occurred in any of the patients, and the survival time of patients following stenting ranged between 70 and 332 days with a mean survival time of 192 days. In conclusion, our methodology for combined biliary and enteral stenting is highly effective for the palliation of malignant biliary and gastric outlet‑duodenal obstruction.

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