Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
October 2014 Volume 8 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October 2014 Volume 8 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Differential diagnosis of eccrine spiradenoma: A case report

  • Authors:
    • Yan Zheng
    • Qiong Tian
    • Juan Wang
    • Xinyu Dong
    • Huiling  Jing
    • Xin Wang
    • Yiguo Feng
    • Shengxiang Xiao

  • View Affiliations / Copyright

    Affiliations: Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China
  • Pages: 1097-1101
    |
    Published online on: August 14, 2014
       https://doi.org/10.3892/etm.2014.1906
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Eccrine spiradenoma (ES) is a rare, benign adnexal neoplasm that may easily be mistaken for glomus lesions or angioleiomyoma due to its painfulness and florid vascularization. A 44‑year‑old male with a blue-colored, nodular tumor on the left knee, present for 10 years, was submitted for diagnosis. Dermatological examination was undertaken, followed by surgical excision of the subcutaneous lesion and histopathological examination of the tissue. Subjective symptoms included tenderness upon palpation and routine investigations were within normal limits. Immunohistochemical analysis of the tumor cells demonstrated positive staining for CK5/CK6, CK8/CK18, S100, as well as small vacuole-like positive for EMA, and was therefore diagnosed as ES. The results of the present study suggest that immunohistochemical assays may be helpful to clarify the diagnosis and differentiate ES from other painful subcutaneous tumors exhibiting similar clinical and histological presentations.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

Figure 9

Figure 10

Figure 11

View References

1 

Nadig SK, Alderdice JM, Adair RA and Rao TJ: Eccrine spiradenoma: an unusual presentation with otalgia. Otolaryngol Head Neck Surg. 130:277–278. 2004. View Article : Google Scholar : PubMed/NCBI

2 

Wong DR, Olson DA and Dresner HS: A rare case of eccrine spiradenoma of the upper lip. The Laryngoscope. 120:S522010. View Article : Google Scholar

3 

Englander L, Emer JJ, McClain D, Amin B and Turner RB: A rare case of multiple segmental eccrine spiradenomas. J Clin Aesthet Dermatol. 4:38–44. 2011.PubMed/NCBI

4 

Kersting DW and Helwig EB: Eccrine spiradenoma. AMA Arch Derm. 73:199–227. 1956. View Article : Google Scholar : PubMed/NCBI

5 

Nath AK, Kumari R and Thappa DM: Eccrine spiradenoma with chondroid syringoma in Blaschkoid distribution. Indian J Dermatol Venereol Leprol. 75:600–602. 2009. View Article : Google Scholar : PubMed/NCBI

6 

Weyers W, Nilles M, Eckert F and Schill WB: Spiradenomas in Brooke-Spiegler syndrome. Am J Dermatopathol. 15:156–161. 1993. View Article : Google Scholar : PubMed/NCBI

7 

Braun-Falco M, Bonel H, Ring J and Hein R: Linear spiradenoma with focal malignant transformation. J Eur Acad Dermatol Venereol. 17:308–312. 2003. View Article : Google Scholar : PubMed/NCBI

8 

Park HR, Im SB, Kim HK, Shin DS and Park YL: Painful eccrine spiradenoma containing nerve fibers: a case report. Dermatology. 224:301–306. 2012. View Article : Google Scholar : PubMed/NCBI

9 

Bumgardner AC, Hsu S, Nunez-Gussman JK and Schwartz MR: Trichoepitheliomas and eccrine spiradenomas with spiradenoma/cylindroma overlap. Int J Dermatol. 44:415–417. 2005. View Article : Google Scholar : PubMed/NCBI

10 

Jin W, Kim GY, Lew BL, et al: Sonographic findings of an eccrine spiradenoma: case report and literature review. J Ultrasound Med. 27:813–818. 2008.PubMed/NCBI

11 

Wong TY, Suster S, Cheek RF and Mihm MC Jr: Benign cutaneous adnexal tumors with combined folliculosebaceous, apocrine, and eccrine differentiation: Clinicopathologic and immunohistochemical study of eight cases. Am J Dermatopathol. 18:124–136. 1996. View Article : Google Scholar

12 

Lian F and Cockerell CJ: Cutaneous appendage tumors: familial cylindromatosis and associated tumors update. Adv Dermatol. 21:217–234. 2005. View Article : Google Scholar : PubMed/NCBI

13 

Andreoli MT and Itani KM: Malignant eccrine spiradenoma: a meta-analysis of reported cases. Am J Surg. 201:695–699. 2011. View Article : Google Scholar : PubMed/NCBI

14 

Ter Poorten MC, Barrett K and Cook J: Familial eccrine spiradenoma: a case report and review of the literature. Dermatol Surg. 29:411–414. 2003.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zheng Y, Tian Q, Wang J, Dong X, Jing H, Wang X, Feng Y and Xiao S: Differential diagnosis of eccrine spiradenoma: A case report. Exp Ther Med 8: 1097-1101, 2014.
APA
Zheng, Y., Tian, Q., Wang, J., Dong, X., Jing, H., Wang, X. ... Xiao, S. (2014). Differential diagnosis of eccrine spiradenoma: A case report. Experimental and Therapeutic Medicine, 8, 1097-1101. https://doi.org/10.3892/etm.2014.1906
MLA
Zheng, Y., Tian, Q., Wang, J., Dong, X., Jing, H., Wang, X., Feng, Y., Xiao, S."Differential diagnosis of eccrine spiradenoma: A case report". Experimental and Therapeutic Medicine 8.4 (2014): 1097-1101.
Chicago
Zheng, Y., Tian, Q., Wang, J., Dong, X., Jing, H., Wang, X., Feng, Y., Xiao, S."Differential diagnosis of eccrine spiradenoma: A case report". Experimental and Therapeutic Medicine 8, no. 4 (2014): 1097-1101. https://doi.org/10.3892/etm.2014.1906
Copy and paste a formatted citation
x
Spandidos Publications style
Zheng Y, Tian Q, Wang J, Dong X, Jing H, Wang X, Feng Y and Xiao S: Differential diagnosis of eccrine spiradenoma: A case report. Exp Ther Med 8: 1097-1101, 2014.
APA
Zheng, Y., Tian, Q., Wang, J., Dong, X., Jing, H., Wang, X. ... Xiao, S. (2014). Differential diagnosis of eccrine spiradenoma: A case report. Experimental and Therapeutic Medicine, 8, 1097-1101. https://doi.org/10.3892/etm.2014.1906
MLA
Zheng, Y., Tian, Q., Wang, J., Dong, X., Jing, H., Wang, X., Feng, Y., Xiao, S."Differential diagnosis of eccrine spiradenoma: A case report". Experimental and Therapeutic Medicine 8.4 (2014): 1097-1101.
Chicago
Zheng, Y., Tian, Q., Wang, J., Dong, X., Jing, H., Wang, X., Feng, Y., Xiao, S."Differential diagnosis of eccrine spiradenoma: A case report". Experimental and Therapeutic Medicine 8, no. 4 (2014): 1097-1101. https://doi.org/10.3892/etm.2014.1906
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team