Research into europium complexes as magnetic resonance imaging contrast agents (Review)

  • Authors:
    • Guocan Han
    • Yangwei Deng
    • Jihong Sun
    • Jun Ling
    • Zhiquan Shen
  • View Affiliations

  • Published online on: February 17, 2015     https://doi.org/10.3892/etm.2015.2297
  • Pages: 1561-1566
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Abstract

Europium (Eu) is a paramagnetic lanthanide element that possesses an outstanding luminescent property. Eu complexes are ideal fluorescence imaging (FI) agents. Eu2+ has satisfactory relaxivity and optical properties, and can realize magnetic resonance (MRI)‑FI dual imaging applications when used with appropriate cryptands that render it oxidatively stable. By contrast, based on the chemical exchange saturation transfer (CEST) mechanism, Eu3+ complexes can provide enhanced MRI sensitivity when used with optimal cryptands, incorporated into polymeric CEST agents or blended with Gd3+. Eu complexes are promising in MRI‑FI dual imaging applications and have a bright future.
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May-2015
Volume 9 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Han G, Deng Y, Sun J, Ling J and Shen Z: Research into europium complexes as magnetic resonance imaging contrast agents (Review). Exp Ther Med 9: 1561-1566, 2015
APA
Han, G., Deng, Y., Sun, J., Ling, J., & Shen, Z. (2015). Research into europium complexes as magnetic resonance imaging contrast agents (Review). Experimental and Therapeutic Medicine, 9, 1561-1566. https://doi.org/10.3892/etm.2015.2297
MLA
Han, G., Deng, Y., Sun, J., Ling, J., Shen, Z."Research into europium complexes as magnetic resonance imaging contrast agents (Review)". Experimental and Therapeutic Medicine 9.5 (2015): 1561-1566.
Chicago
Han, G., Deng, Y., Sun, J., Ling, J., Shen, Z."Research into europium complexes as magnetic resonance imaging contrast agents (Review)". Experimental and Therapeutic Medicine 9, no. 5 (2015): 1561-1566. https://doi.org/10.3892/etm.2015.2297