Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
May-2015 Volume 9 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2015 Volume 9 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Review

Association between preeclampsia and the CXC chemokine family (Review)

  • Authors:
    • Xijing Liu
    • Li Dai
    • Rong Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
  • Pages: 1572-1576
    |
    Published online on: March 9, 2015
       https://doi.org/10.3892/etm.2015.2337
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Preeclampsia is a major cause of maternal and perinatal mortality and morbidity, characterized by gestational hypertension, proteinuria, systemic endothelial cell activation and an exaggerated inflammatory response. The precise cause of preeclampsia is not currently known; however, it is widely accepted that the pathogenesis of preeclampsia involves inadequate trophoblast invasion, leading to generalized endothelial dysfunction and an exaggerated inflammatory response. Chemokines are a superfamily of structurally similar proteins that mediate cell recruitment, angiogenesis, immunity and stem cell trafficking. CXC chemokines are a family of cytokines, unique in their ability to behave in a disparate manner in the regulation of angiogenesis. The CXC chemokine family further divides into two subfamilies; CXC ELR+, which promotes angiogenesis, and CXC ELR-, which inhibits angiogenesis. Furthermore, CXC chemokines are involved in the pathogenesis of various conditions, including malignant tumors, wound repair, chronic inflammation, atherosclerosis and potentially preeclampsia.
View Figures
View References

1 

Roberts JM and Hubel CA: The two stage model of preeclampsia: variations on the theme. Placenta. 30(Suppl A): S32–S37. 2009. View Article : Google Scholar : PubMed/NCBI

2 

Raymond D and Peterson E: A critical review of early-onset and late-onset preeclampsia. Obstet Gynecol Surv. 66:497–506. 2011. View Article : Google Scholar : PubMed/NCBI

3 

Redman CW: Platelets and the beginnings of preeclampsia. N Engl J Med. 323:478–480. 1990. View Article : Google Scholar : PubMed/NCBI

4 

Carty DM, Delles C and Dominiczak AF: Novel biomarkers for predicting preeclampsia. Trends Cardiovasc Med. 18:186–194. 2008. View Article : Google Scholar : PubMed/NCBI

5 

Gauster M, Moser G, Orendi K and Huppertz B: Factors involved in regulating trophoblast fusion: potential role in the development of preeclampsia. Placenta. 30(Suppl A): S49–S54. 2009. View Article : Google Scholar : PubMed/NCBI

6 

Goldman-Wohl D and Yagel S: Regulation of trophoblast invasion: from normal implantation to pre-eclampsia. Mol Cell Endocrinol. 187:233–238. 2002. View Article : Google Scholar : PubMed/NCBI

7 

Kim YN, Lee DS, Jeong DH, et al: The relationship of the level of circulating antiangiogenic factors to the clinical manifestations of preeclampsia. Prenat Diagn. 29:464–470. 2009. View Article : Google Scholar : PubMed/NCBI

8 

Steinberg G, Khankin EV and Karumanchi SA: Angiogenic factors and preeclampsia. Thromb Res. 123(Suppl 2): S93–S99. 2009. View Article : Google Scholar : PubMed/NCBI

9 

Cerdeira AS and Karumanchi SA: Angiogenic factors in preeclampsia and related disorders. Cold Spring Harb Perspect Med. 2(pii): a0065852012.PubMed/NCBI

10 

Hirashima C, Ohkuchi A, Matsubara S, et al: Alteration of serum soluble endoglin levels after the onset of preeclampsia is more pronounced in women with early-onset. Hypertens Res. 31:1541–1548. 2008. View Article : Google Scholar : PubMed/NCBI

11 

Zlotnik A and Yoshie O: Chemokines: a new classification system and their role in immunity. Immunity. 12:121–127. 2000. View Article : Google Scholar : PubMed/NCBI

12 

Keeley EC, Mehrad B and Strieter RM: Chemokines as mediators of neovascularization. Arterioscler Thromb Vasc Biol. 28:1928–1936. 2008. View Article : Google Scholar : PubMed/NCBI

13 

Addison CL, Daniel TO, Burdick MD, et al: The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity. J Immunol. 165:5269–5277. 2000. View Article : Google Scholar : PubMed/NCBI

14 

Strieter RM, Polverini PJ, Kunkel SL, et al: The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J Biol Chem. 270:27348–27357. 1995. View Article : Google Scholar : PubMed/NCBI

15 

Mehrad B, Keane MP and Strieter RM: Chemokines as mediators of angiogenesis. Thromb Haemost. 97:755–762. 2007.PubMed/NCBI

16 

Maione TE, Gray GS, Petro J, et al: Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides. Science. 247:77–79. 1990. View Article : Google Scholar : PubMed/NCBI

17 

Keeley EC, Mehrad B and Strieter RM: Chemokines as mediators of tumor angiogenesis and neovascularization. Exp Cell Res. 317:685–690. 2011. View Article : Google Scholar : PubMed/NCBI

18 

Loukinova E, Dong G, Enamorado-Ayalya I, et al: Growth regulated oncogene-alpha expression by murine squamous cell carcinoma promotes tumor growth, metastasis, leukocyte infiltration and angiogenesis by a host CXC receptor-2 dependent mechanism. Oncogene. 19:3477–3486. 2000. View Article : Google Scholar : PubMed/NCBI

19 

Murphy PM: The molecular biology of leukocyte chemoattractant receptors. Annu Rev Immunol. 12:593–633. 1994. View Article : Google Scholar : PubMed/NCBI

20 

Ahuja SK and Murphy PM: The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor. J Biol Chem. 271:20545–20550. 1996. View Article : Google Scholar : PubMed/NCBI

21 

Loetscher M, Gerber B, Loetscher P, et al: Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 184:963–969. 1996. View Article : Google Scholar : PubMed/NCBI

22 

Kakinuma T and Hwang ST: Chemokines, chemokine receptors, and cancer metastasis. J Leukoc Biol. 79:639–651. 2006. View Article : Google Scholar : PubMed/NCBI

23 

Tanegashima K, Suzuki K, Nakayama Y, et al: CXCL14 is a natural inhibitor of the CXCL12-CXCR4 signaling axis. FEBS Lett. 587:1731–1735. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Balabanian K, Lagane B, Infantino S, et al: The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem. 280:35760–35766. 2005. View Article : Google Scholar : PubMed/NCBI

25 

Strieter RM, Burdick MD, Mestas J, et al: Cancer CXC chemokine networks and tumour angiogenesis. Eur J Cancer. 42:768–778. 2006. View Article : Google Scholar : PubMed/NCBI

26 

Yoneda J, Kuniyasu H, Crispens MA, et al: Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice. J Natl Cancer Inst. 90:447–454. 1998. View Article : Google Scholar : PubMed/NCBI

27 

Arenberg DA, Keane MP, DiGiovine B, et al: Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer. J Clin Invest. 102:465–472. 1998. View Article : Google Scholar : PubMed/NCBI

28 

Addison CL, Belperio JA, Burdick MD and Strieter RM: Overexpression of the duffy antigen receptor for chemokines (DARC) by NSCLC tumor cells results in increased tumor necrosis. BMC Cancer. 4:282004. View Article : Google Scholar : PubMed/NCBI

29 

White ES, Flaherty KR, Carskadon S, et al: Macrophage migration inhibitory factor and CXC chemokine expression in non-small cell lung cancer: role in angiogenesis and prognosis. Clin Cancer Res. 9:853–860. 2003.PubMed/NCBI

30 

Arenberg DA, Kunkel SL, Polverini PJ, et al: Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice. J Clin Invest. 97:2792–2802. 1996. View Article : Google Scholar : PubMed/NCBI

31 

Moore BB, Arenberg DA, Stoy K, et al: Distinct CXC chemokines mediate tumorigenicity of prostate cancer cells. Am J Pathol. 154:1503–1512. 1999. View Article : Google Scholar : PubMed/NCBI

32 

Wente MN, Keane MP, Burdick MD, et al: Blockade of the chemokine receptor CXCR2 inhibits pancreatic cancer cell-induced angiogenesis. Cancer Lett. 241:221–227. 2006. View Article : Google Scholar : PubMed/NCBI

33 

Moser B and Loetscher P: Lymphocyte traffic control by chemokines. Nat Immunol. 2:123–128. 2001. View Article : Google Scholar : PubMed/NCBI

34 

Lasagni L, Francalanci M, Annunziato F, et al: An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. J Exp Med. 197:1537–1549. 2003. View Article : Google Scholar : PubMed/NCBI

35 

Ehlert JE, Addison CA, Burdick MD, et al: Identification and partial characterization of a variant of human CXCR3 generated by posttranscriptional exon skipping. J Immunol. 173:6234–6240. 2004. View Article : Google Scholar : PubMed/NCBI

36 

Yang J and Richmond A: The angiostatic activity of interferon-inducible protein-10/CXCL10 in human melanoma depends on binding to CXCR3 but not to glycosaminoglycan. Mol Ther. 9:846–855. 2004. View Article : Google Scholar : PubMed/NCBI

37 

Strieter RM, Burdick MD, Gomperts BN, et al: CXC chemokines in angiogenesis. Cytokine Growth Factor Rev. 16:593–609. 2005. View Article : Google Scholar : PubMed/NCBI

38 

Cole KE, Strick CA, Paradis TJ, et al: Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J Exp Med. 187:2009–2021. 1998. View Article : Google Scholar : PubMed/NCBI

39 

Coughlin CM, Salhany KE, Wysocka M, et al: Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis. J Clin Invest. 101:1441–1452. 1998. View Article : Google Scholar : PubMed/NCBI

40 

Borgström P, Discipio R and Maione TE: Recombinant platelet factor 4, an angiogenic marker for human breast carcinoma. Anticancer Res. 18:4035–4041. 1998.PubMed/NCBI

41 

Gupta SK and Singh JP: Inhibition of endothelial cell proliferation by platelet factor-4 involves a unique action on S phase progression. J Cell Biol. 127:1121–1127. 1994. View Article : Google Scholar : PubMed/NCBI

42 

Sgadari C, Angiolillo AL, Cherney BW, et al: Interferon-inducible protein-10 identified as a mediator of tumor necrosis in vivo. In: Proc Natl Acad Sci USA. 93. pp. 13791–13796. 1996; View Article : Google Scholar : PubMed/NCBI

43 

Arenberg DA, Kunkel SL, Polverini PJ, et al: Interferon-gamma-inducible protein 10 (IP-10) is an angiostatic factor that inhibits human non-small cell lung cancer (NSCLC) tumorigenesis and spontaneous metastases. J Exp Med. 184:981–992. 1996. View Article : Google Scholar : PubMed/NCBI

44 

Arenberg DA, White ES, Burdick MD, et al: Improved survival in tumor-bearing SCID mice treated with interferon-gamma-inducible protein 10 (IP-10/CXCL10). Cancer Immunol Immunother. 50:533–538. 2001. View Article : Google Scholar : PubMed/NCBI

45 

Balkwill F: Cancer and the chemokine network. Nat Rev Cancer. 4:540–550. 2004. View Article : Google Scholar : PubMed/NCBI

46 

Müller A, Homey B, Soto H, et al: Involvement of chemokine receptors in breast cancer metastasis. Nature. 410:50–56. 2001. View Article : Google Scholar : PubMed/NCBI

47 

Zagzag D, Lukyanov Y, Lan L, et al: Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion. Lab Invest. 86:1221–1232. 2006. View Article : Google Scholar : PubMed/NCBI

48 

Sun X, Cheng G, Hao M, et al: CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression. Cancer Metastasis Rev. 29:709–722. 2010. View Article : Google Scholar : PubMed/NCBI

49 

Burns JM, Summers BC, Wang Y, et al: A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med. 203:2201–2213. 2006. View Article : Google Scholar : PubMed/NCBI

50 

Maishi N, Ohga N, Hida Y, et al: CXCR7: a novel tumor endothelial marker in renal cell carcinoma. Pathol Int. 62:309–317. 2012. View Article : Google Scholar : PubMed/NCBI

51 

Song EY, Shurin MR, Tourkova IL, et al: Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells. Cancer Res. 70:4394–4401. 2010. View Article : Google Scholar : PubMed/NCBI

52 

Tessema M, Klinge DM, Yingling CM, et al: Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis. Oncogene. 29:5159–5170. 2010. View Article : Google Scholar : PubMed/NCBI

53 

Jovanović M, Stefanoska I, Radojcić L and Vićovac L: Interleukin-8 (CXCL8) stimulates trophoblast cell migration and invasion by increasing levels of matrix metalloproteinase (MMP)2 and MMP9 and integrins alpha5 and beta1. Reproduction. 139:789–798. 2010. View Article : Google Scholar : PubMed/NCBI

54 

Kuang H, Chen Q, Zhang Y, et al: The cytokine gene CXCL14 restricts human trophoblast cell invasion by suppressing gelatinase activity. Endocrinology. 150:5596–5605. 2009. View Article : Google Scholar : PubMed/NCBI

55 

Kuang H, Chen Q, Fan X, et al: CXCL14 inhibits trophoblast outgrowth via a paracrine/autocrine manner during early pregnancy in mice. J Cell Physiol. 221:448–457. 2009. View Article : Google Scholar : PubMed/NCBI

56 

Li MQ, Tang CL, Du MR, et al: CXCL12 controls over-invasion of trophoblasts via upregulating CD82 expression in DSCs at maternal-fetal interface of human early pregnancy in a paracrine manner. Int J Clin Exp Pathol. 4:276–286. 2011.PubMed/NCBI

57 

Gotsch F, Romero R, Friel L, et al: CXCL10/IP-10: a missing link between inflammation and anti-angiogenesis in preeclampsia? J Matern Fetal Neonatal Med. 20:777–792. 2007. View Article : Google Scholar : PubMed/NCBI

58 

Boij R, Svensson J, Nilsson-Ekdahl K, et al: Biomarkers of coagulation, inflammation, and angiogenesis are independently associated with preeclampsia. Am J Reprod Immunol. 68:258–270. 2012. View Article : Google Scholar : PubMed/NCBI

59 

Schanz A, Winn VD, Fisher SJ, et al: Pre-eclampsia is associated with elevated CXCL12 levels in placental syncytiotrophoblasts and maternal blood. Eur J Obstet Gynecol Reprod Biol. 157:32–37. 2011. View Article : Google Scholar : PubMed/NCBI

60 

Gui S, Ni S, Jia J, Gong Y, Gao L, Zhang L and Zhou R: Inconformity of CXCL3 plasma level and placenta expression in preeclampsia and its effect on trophoblast viability and invasion. PLoS One. 9:e1144082014. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Liu X, Dai L and Zhou R: Association between preeclampsia and the CXC chemokine family (Review). Exp Ther Med 9: 1572-1576, 2015.
APA
Liu, X., Dai, L., & Zhou, R. (2015). Association between preeclampsia and the CXC chemokine family (Review). Experimental and Therapeutic Medicine, 9, 1572-1576. https://doi.org/10.3892/etm.2015.2337
MLA
Liu, X., Dai, L., Zhou, R."Association between preeclampsia and the CXC chemokine family (Review)". Experimental and Therapeutic Medicine 9.5 (2015): 1572-1576.
Chicago
Liu, X., Dai, L., Zhou, R."Association between preeclampsia and the CXC chemokine family (Review)". Experimental and Therapeutic Medicine 9, no. 5 (2015): 1572-1576. https://doi.org/10.3892/etm.2015.2337
Copy and paste a formatted citation
x
Spandidos Publications style
Liu X, Dai L and Zhou R: Association between preeclampsia and the CXC chemokine family (Review). Exp Ther Med 9: 1572-1576, 2015.
APA
Liu, X., Dai, L., & Zhou, R. (2015). Association between preeclampsia and the CXC chemokine family (Review). Experimental and Therapeutic Medicine, 9, 1572-1576. https://doi.org/10.3892/etm.2015.2337
MLA
Liu, X., Dai, L., Zhou, R."Association between preeclampsia and the CXC chemokine family (Review)". Experimental and Therapeutic Medicine 9.5 (2015): 1572-1576.
Chicago
Liu, X., Dai, L., Zhou, R."Association between preeclampsia and the CXC chemokine family (Review)". Experimental and Therapeutic Medicine 9, no. 5 (2015): 1572-1576. https://doi.org/10.3892/etm.2015.2337
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team