Acupuncture: Emerging evidence for its use as an analgesic (Review)
- Authors:
- Peng Gao
- Xi Gao
- Tairan Fu
- Dan Xu
- Qingping Wen
-
Affiliations: Department of Anesthesiology, Dalian Medical University, Dalian, Liaoning 116044, P.R. China, Department of Anesthesiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China - Published online on: March 12, 2015 https://doi.org/10.3892/etm.2015.2348
- Pages: 1577-1581
This article is mentioned in:
Abstract
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Yang L, Yue N, Zhu X, Han Q, Li B, Liu Q, Wu G and Yu J: Electroacupuncture promotes proliferation of amplifying neural progenitors and preserves quiescent neural progenitors from apoptosis to alleviate depressive-like and anxiety-like behaviours. Evid Based Complement Alternat Med. 2014:8725682014. View Article : Google Scholar : PubMed/NCBI | |
|
Xu T, Li W, Liang Y, Yang Z, Liu J, Wang Y and Su N: Neuroprotective effects of electro acupuncture on hypoxic-ischemic encephalopathy in newborn rats Ass. Pak J Pharm Sci. 27(6 Suppl): 1991–2000. 2014.PubMed/NCBI | |
|
Yu J and Zhou J: Effect of auricular point sticking on lactation of puerperant. Zhongguo Zhen Jiu. 32:1087–1089. 2012.[In Chinese]. PubMed/NCBI | |
|
Bigeleisen PE and Goehner N: Novel approaches in pain management in cardiac surgery. Curr Opin Anaesthesiol. 28:89–94. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Hinman RS, McCrory P, Pirotta M, et al: Acupuncture for chronic knee pain: A randomized clinical trial. JAMA. 312:1313–1322. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Wu C, Qu S, Zhang J, Chen J, Zhang S, Li Z, Chen J, Ouyang H, Huang Y and Tang C: Correlation between the effects of acupuncture at Taichong (LR3) and functional brain areas: A resting-state functional magnetic resonance imaging study using true versus sham acupuncture. Evid Based Complement Alternat Med. 2014.7290912014.PubMed/NCBI | |
|
Fang JQ, Fang JF, Liang Y and Du JY: Electroacupuncture mediates extracellular signal-regulated kinase 1/2 pathways in the spinal cord of rats with inflammatory pain. BMC Complement Altern Med. 14:2852014. View Article : Google Scholar : PubMed/NCBI | |
|
Li C, Yang J, Park K, Wu H, Hu S, Zhang W, Bu J, Xu C, Qiu B and Zhang X: Prolonged repeated acupuncture stimulation induces habituation effects in pain-related brain areas: An FMRI study. PLoS One. 9:e975022014. View Article : Google Scholar : PubMed/NCBI | |
|
Kim KH, Ryu JH, Park MR, et al: Acupuncture as analgesia for non-emergent acute non-specific neck pain, ankle sprain and primary headache in an emergency department setting: A protocol for a parallel group, randomised, controlled pilot trial. BMJ Open. 4:e0049942014. View Article : Google Scholar : PubMed/NCBI | |
|
Moré AO, Cidral-Filho FJ, Mazzardo-Martins L, Martins DF, Nascimento FP, Li SM and Santos AR: Caffeine at moderate doses can inhibit acupuncture-induced analgesia in a mouse model of postoperative pain. J Caffeine Res. 3:143–148. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Grillo CM, Wada RS and da Luz Rosário de Sousa M: Acupuncture in the management of acute dental pain. J Acupunct Meridian Stud. 7:65–70. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Ruan H, Li X and Cai W: Effect of 5-HT and somatostatin on SP and chronic pain initiated electrical activity of neurons in spinal dorsal horn. Zhen Ci Yan Jiu. 21:27–31. 1996.[In Chinese]. PubMed/NCBI | |
|
Qiao LN, Yang YS, Wang JY, Gao YH, Han YJ, Chen SP, Ji CF and Liu JL: Effects of electroacupuncture at “Futu” (LI 18), etc. on expression of spinal 5-HT 1 AR mRNA, 5-HT 2 AR mRNA and protein in rats with neck incision pain. Zhen Ci Yan Jiu. 36:391–396. 2011.PubMed/NCBI | |
|
Schaible HG: Basic mechanisms of deep somatic painWall and Melzacks Textbook of Pain. McMahon SB and Koltzenburg M: Churchill-Livingston; London: pp. 621–633. 2006, View Article : Google Scholar | |
|
Zyloney CE, Jensen K, Polich G, Loiotile RE, Cheetham A, LaViolette PS, Tu P, Kaptchuk TJ, Gollub RL and Kong J: Imaging the functional connectivity of the Periaqueductal Gray during genuine and sham electroacupuncture treatment. Mol Pain. 6:802010. View Article : Google Scholar : PubMed/NCBI | |
|
Tobaldini G, Aisengart B, Lima MMS, Tambeli CH and Fischer L: Ascending nociceptive control contributes to the antinociceptive effect of acupuncture in a rat model of acute pain. J Pain. 15:422–434. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Lee CH, Jung HS, Lee TY, Lee SR, Yuk SW, Lee KG and Lee BH: Studies of the central neural pathways to the stomach and Zusanli (ST36). Am J Chin Med. 29:211–220. 2001. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang Y, Zhang RX, Zhang M, Shen XY, Li A, Xin J, Ren K, Berman BM, Tan M and Lao L: Electroacupuncture inhibition of hyperalgesia in an inflammatory pain rat model: Involvement of distinct spinal serotonin and norepinephrine receptor subtypes. Br J Anaesth. 109:245–252. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Kim KW, Kim HW, Li J and Kwon YB: Effect of bee venom acupuncture on methamphetamine-induced hyperactivity, hyperthermia and Fos expression in mice. Brain Res Bull. 84:61–68. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Shelton L, Pendse G, Maleki N, Moulton EA, Lebel A, Becerra L and Borsook D: Mapping pain activation and connectivity of the human habenula. J Neurophysiol. 107:2633–2648. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Liu GJ and Wang S: Effects of nucleus raphe magnus and locus coeruleus in descending modulation of the habenula on pain threshold and acupuncture analgesia. Zhongguo Yao Li Xue Bao. 9:18–22. 1988.[In Chinese]. PubMed/NCBI | |
|
Wang H, Jiang J and Can X: Changes of norepinephrine release in rats nucleus reticularis paragigantocellularis lateralis in acupuncture analgesia. Zhen Ci Yan Jiu. 19:20–25. 1994.[In Chinese]. PubMed/NCBI | |
|
Wang JY, Meng FY, Chen SP, Gao YH and Liu JL: Analysis on interrelation between electroacupuncture-induced cumulative analgesic effect and hypothalamic cholinergic activities in chronic neuropathic pain rats. Chin J Integr Med. 18:699–707. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Guan X, Wang C, Yu B, Liang X, Zhang Y, Zeng X, Liu X, Shi J and Ai M: Research on the relationship between central acetylcholine and acupuncture analgesia. Zhen Ci Yan Jiu. 16:129–137. 1991.[In Chinese]. PubMed/NCBI | |
|
Wang JY, Chen SP, Li YH, Meng FY, Gao YH and Liu JL: Observation on the accumulative analgesic effect of electroacupuncture and the expression of protein kinase A in hypothalamus and hippocampus in chronic pain or/and ovariectomized rats. Zhen Ci Yan Jiu. 33:80–87. 2008.[In Chinese]. PubMed/NCBI | |
|
Xu Q, Liu T, Chen S, Gao Y, Wang J, Qiao L and Liu J: Correlation between the cumulative analgesic effect of electroacupuncture intervention and synaptic plasticity of hypothalamic paraventricular nucleus neurons in rats with sciatica. Neural Regen Res. 8:218–225. 2013.PubMed/NCBI | |
|
Zhu JM, Li KY and Cao XD: Effects of destruction of preoptic catecholaminergic nerve terminals on acupuncture analgesia. Sheng Li Xue Bao. 42:135–140. 1990.[In Chinese]. PubMed/NCBI | |
|
Wang SJ, Zhu B, Ren XX, Ben H, Li YQ and Li YH: Effect of acupuncture of different acupoints on electrical activities of hypothalamic sexual arousal stimulation-related neurons at different stages of oestrous cycle in rats. Zhen Ci Yan Jiu. 32:313–318. 2007.[In Chinese]. PubMed/NCBI | |
|
Newberg AB, Lariccia PJ, Lee BY, Farrar JT, Lee L and Alavi A: Cerebral blood flow effects of pain and acupuncture: A preliminary single-photon emission computed tomography imaging study. J Neuroimaging. 15:43–49. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Yi M, Zhang H, Lao L, Xing GG and Wan Y: Anterior cingulate cortex is crucial for contra- but not ipsi-lateral electro-acupuncture in the formalin-induced inflammatory pain model of rats. Mol Pain. 7:612011. View Article : Google Scholar : PubMed/NCBI | |
|
Li J, Zhang JH, Yi T, Tang WJ, Wang SW and Dong JC: Acupuncture treatment of chronic low back pain reverses an abnormal brain default mode network in correlation with clinical pain relief. Acupunct Med. 32:102–108. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Huang C, Wang Y, Chang JK and Han JS: Endomorphin and mu-opioid receptors in mouse brain mediate the analgesic effect induced by 2 Hz but not 100 Hz electroacupuncture stimulation. Neurosci Lett. 294:159–162. 2000. View Article : Google Scholar : PubMed/NCBI | |
|
Harris RE, Zubieta JK, Scott DJ, Napadow V, Gracely RH and Clauw DJ: Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on mu-opioid receptors (MORs). Neuroimage. 47:1077–1085. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Pasternak GW: Pharmacological mechanisms of opioid analgesics. Clin Neuropharmacol. 16:1–18. 1993. View Article : Google Scholar : PubMed/NCBI | |
|
Han JS: Acupuncture and endorphins. Neurosci Lett. 361:258–261. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang GG, Yu C, Lee W, Lao L, Ren K and Berman BM: Involvement of peripheral opioid mechanisms in electroacupuncture analgesia. Explore (NY). 1:365–371. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Cabot PJ, Carter L, Schäfer M and Stein C: Methionine-enkephalin and Dynorphin A-release from immune cells and control of inflammatory pain. Pain. 93:207–212. 2001. View Article : Google Scholar : PubMed/NCBI | |
|
Cheng XD, Wu GC, He QZ and Cao XD: Effect of continued electroacupuncture on induction of interleukin-2 production of spleen lymphocytes from the injured rats. Acupunct Electrother Res. 22:1–8. 1997.PubMed/NCBI | |
|
Miao EY: Clinical critical qualitative evaluation of the selected randomized controlled trials in current acupuncture researches for low back pain. Zhong Xi Yi Jie He Xue Bao. 8:1133–1146. 2010.[In Chinese]. View Article : Google Scholar : PubMed/NCBI | |
|
Weiss J, Quante S, Xue F, Muche R and Reuss-Borst M: Effectiveness and acceptance of acupuncture in patients with chronic low back pain: Results of a prospective, randomized, controlled trial. J Altern Complement Med. 19:935–941. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Goldman N, Chen M, Fujita T, et al: Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nat Neurosci. 13:883–888. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Meeus M, Nijs J, Van de Wauwer N, Toeback L and Truijen S: Diffuse noxious inhibitory control is delayed in chronic fatigue syndrome: An experimental study. Pain. 139:439–448. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Cao W, Deng Y, Dong X, Wang Y and Lu Z: Effects of electroacupuncture at different frequencies on the nociceptive response and central contents of GABA and glutamic acid in arthritic rats. Zhen Ci Yan Jiu. 18:48–52. 1993.[In Chinese]. PubMed/NCBI | |
|
Li X, Zhou K, Zhang E, Qi Z, Sun W, Xu L, Xu J, Cai Y and Wang R: Therapeutic effect of electroacupuncture, massage, and blocking therapy on external humeral epicondylitis. J Tradit Chin Med. 34:261–266. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Malan TP Jr, Mata HP and Porreca F: Spinal GABA(A) and GABA(B) receptor pharmacology in a rat model of neuropathic pain. Anesthesiology. 96:1161–1167. 2002. View Article : Google Scholar : PubMed/NCBI | |
|
Knabl J, Witschi R, Hösl K, et al: Reversal of pathological pain through specific spinal GABAA receptor subtypes. Nature. 451:330–334. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Tambeli CH, Quang P, Levine JD and Gear RW: Contribution of spinal inhibitory receptors in heterosegmental antinociception induced by noxious stimulation. Eur J Neurosci. 18:2999–3006. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Hu JH, Yang N, Ma YH, Zhou XG, Jiang J, Duan SH, Mei ZT, Fei J and Guo LH: Hyperalgesic effects of γ-aminobutyric acid transporter I in mice. J Neurosci Res. 73:565–572. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Moon JY, Roh DH, Yoon SY, et al: σ1 receptors activate astrocytes via p38 MAPK phosphorylation leading to the development of mechanical allodynia in a mouse model of neuropathic pain. Br J Pharmacol. 171:5881–5897. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Gong QJ, Li YY, Xin WJ, Zang Y, Ren WJ, Wei XH, Li YY, Zhang T and Liu XG: ATP induces long-term potentiation of C-fiber-evoked field potentials in spinal dorsal horn: The roles of P2×4 receptors and p38 MAPK in microglia. Glia. 57:583–591. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Pu L, Xu N, Xia P, Gu Q, Ren S, Fucke T, Pei G and Schwarz W: Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor. Evid Based Complement Alternat Med. 2012.8184512012.PubMed/NCBI | |
|
Cui XY, Dai Y, Wang SL, Yamanaka H, Kobayashi K, Obata K, Chen J and Noguchi K: Differential activation of p38 and extracellular signal-regulated kinase in spinal cord in a model of bee venom-induced inflammation and hyperalgesia. Mol Pain. 4:172008. View Article : Google Scholar : PubMed/NCBI | |
|
Zaringhalam J, Tekieh E, Manaheji H and Akhtari Z: Cellular events during arthritis-induced hyperalgesia are mediated by interleukin-6 and p38 MAPK and their effects on the expression of spinal mu-opioid receptors. Rheumatol Int. 33:2291–2299. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Fang JQ, Du JY, Liang Y and Fang JF: Intervention of electroacupuncture on spinal p38 MAPK/ATF-2/VR-1 pathway in treating inflammatory pain induced by CFA in rats. Mol Pain. 9:132013. View Article : Google Scholar : PubMed/NCBI | |
|
Boyle DL, Jones TL, Hammaker D, Svensson CI, Rosengren S, Albani S, Sorkin L and Firestein GS: Regulation of peripheral inflammation by spinal p38 MAP kinase in rats. PLoS Med. 3:e3382006. View Article : Google Scholar : PubMed/NCBI | |
|
Park JY, Park JJ, Jeon S, Doo AR, Kim SN, Lee H, Chae Y, Maixner W, Lee H and Park HJ: From peripheral to central: The role of ERK signaling pathway in acupuncture analgesia. J Pain. 15:535–549. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Cheng SJ, Chen CC, Yang HW, Chang YT, Bai SW, Chen CC, Yen CT and Min MY: Role of extracellular signal-regulated kinase in synaptic transmission and plasticity of a nociceptive input on capsular central amygdaloid neurons in normal and acid-induced muscle pain mice. J Neurosci. 31:2258–2270. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Lu J, Liang J, Wang JR, Hu L, Tu Y and Guo JY: Acupuncture activates ERK-CREB pathway in rats exposed to chronic unpredictable mild stress. Evid Based Complement Alternat Med. 2013:4697652013. View Article : Google Scholar : PubMed/NCBI | |
|
Wang SJ, Yang HY and Xu GS: Acupuncture alleviates colorectal hypersensitivity and correlates with the regulatory mechanism of TrpV1 and p-ERK. Evid Based Complement Alternat Med. 2012.4831232012.PubMed/NCBI | |
|
Shi X, Wang L, Clark JD and Kingery WS: Keratinocytes express cytokines and nerve growth factor in response to neuropeptide activation of the ERK1/2 and JNK MAPK transcription pathways. Regul Pept. 186:92–103. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Sekido R, Ishimaru K and Sakita M: Corticotropin-releasing factor and interleukin-1beta are involved in the electroacupuncture-induced analgesic effect on inflammatory pain elicited by carrageenan. Am J Chin Med. 32:269–279. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Gonzalez-Rey E, Chorny A, Fernandez-Martin A, Ganea D and Delgado M: Vasoactive intestinal peptide generates human tolerogenic dendritic cells that induce CD4 and CD8 regulatory T cells. Blood. 107:3632–3638. 2006. View Article : Google Scholar : PubMed/NCBI | |
|
Atanassova N, McKinnell C, Fisher J and Sharpe RM: Neonatal treatment of rats with diethylstilboestrol (DES) induces stromal-epithelial abnormalities of the vas deferens and cauda epididymis in adulthood following delayed basal cell development. Reproduction. 129:589–601. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Huang T, Yang L, Jia S, Mu X, Wu M, Ye H, Liu W and Cheng X: Capillary blood flow in patients with dysmenorrhea treated with acupuncture. J Tradit Chin Med. 33:757–760. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Li ZZ, Chen JZ, Guo Y, Guo YM and Liu YY: Influence of acupuncture or thermal acupuncture stimulation at ʻZusanliʼ (ST 36) on thoracic duct lymph volume and the relevant chemical substances in normal rats. Zhen Ci Yan Jiu. 37:453–457. 2012.[In Chinese]. PubMed/NCBI | |
|
Fu X, Zhu ZH, Wang YQ and Wu GC: Regulation of proinflammatory cytokines gene expression by nociceptin/orphanin FQ in the spinal cord and the cultured astrocytes. Neuroscience. 144:275–285. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Gao YH, Wang JY, Qiao LN, Chen SP, Tan LH, Xu QL and Liu JL: NK cells mediate the cumulative analgesic effect of electroacupuncture in a rat model of neuropathic pain. BMC Complement Altern Med. 14:3162014. View Article : Google Scholar : PubMed/NCBI | |
|
Peng G: Acupuncture and innate immunity. Zhen Ci Yan Jiu. 33:49–52. 2008.[In Chinese]. PubMed/NCBI | |
|
Jeong HJ, Hong SH, Nam YC, Yang HS, Lyu YS, Baek SH, Lee HJ and Kim HM: The effect of acupuncture on proinflammatory cytokine production in patients with chronic headache: A preliminary report. Am J Chin Med. 31:945–954. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Yu JN, Guo CQ, Hu B, Liu NG, et al: Effects of acupuncture knife on inflammatory factors and pain in third lumbar vertebrae transverse process syndrome model rats. Evid Based Complement Alternat Med. 2014.8924062014.PubMed/NCBI | |
|
Erthal V, da Silva MD, Cidral-Filho FJ, Santos AR and Nohama P: ST36 laser acupuncture reduces pain-related behavior in rats: Involvement of the opioidergic and serotonergic systems. Lasers Med Sci. 28:1345–1351. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Kayser V, Elfassi IE, Aubel B, Melfort M, Julius D, Gingrich JA, Hamon M and Bourgoin S: Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A-/-, 5-HT1B-/-, 5-HT2A-/-, 5-HT3A-/- and 5-HTT-/- knock-out male mice. Pain. 130:235–248. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Huang C, Hu ZP, Jiang SZ, Li HT, Han JS and Wan Y: CCK(B) receptor antagonist L365,260 potentiates the efficacy to and reverses chronic tolerance to electroacupuncture-induced analgesia in mice. Brain Res Bull. 71:447–451. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Li M, Tjen-A-Looi SC, Guo ZL and Longhurst JC: Electroacupuncture modulation of reflex hypertension in rats: Role of cholecystokinin octapeptide. Am J Physiol Regul Integr Comp Physiol. 305:R404–R413. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Yamada Y, Ohinata K, Lipkowski AW and Yoshikawa M: Rapakinin, Arg-Ile-Tyr, derived from rapeseed napin, shows anti-opioid activity via the prostaglandin IP receptor followed by the cholecystokinin CCK(2) receptor in mice. Peptides. 32:281–285. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Romanelli L, Morrone LA, Amico MC, Palmery M, Tucci P and Valeri P: Inhibitory control of the acute mu-withdrawal response by indirectly activated adenosine A1 and kappa-opioid systems in the Guinea-pig ileum; reversal by cholecystokinin. Neurotoxicology. 26:829–839. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Du J and He L: Alterations of spinal dorsal horn substance P following electroacupuncture analgesia - A study of the formalin test with immunohistochemistry and densitometry. Acupunct Electrother Res. 17:1–6. 1992.PubMed/NCBI | |
|
Huang B, Zhou ZL, Wang LL, Zuo C, Lu Y and Chen Y: Electrical response grading versus House-Brackmann scale for evaluation of facial nerve injury after Bells palsy: A comparative study. J Integr Med. 12:367–371. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Shokrani O, Saghaei M, Ashrafi F and Sadeghi A: Electrical stimulation of acupuncture points for analgesia during bone marrow aspiration and biopsy: A randomized double-blind placebo-controlled trial. Adv Biomed Res. 3:1252014. View Article : Google Scholar : PubMed/NCBI |
