Vitamin D receptor gene polymorphisms and musculoskeletal injuries in professional football players

  • Authors:
    • Myosotis Massidda
    • Laura Corrias
    • Valeria Bachis
    • Paolo Cugia
    • Francesco Piras
    • Marco Scorcu
    • Carla M. Calò
  • View Affiliations

  • Published online on: March 16, 2015     https://doi.org/10.3892/etm.2015.2364
  • Pages: 1974-1978
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Abstract

The aim of the present study was to investigate the association between vitamin D receptor (VDR) gene polymorphisms and musculoskeletal injury (MI) in elite football players. In total, 54 male professional football players were recruited from an official Italian professional championship team between 2009 and 2013. The cohort was genotyped for the ApaI, BsmI and FokI polymorphisms and MI data were collected over four football seasons. No significant differences were identified among the genotypes in the incidence rates or severity of MI (P=0.254). In addition, no significant associations were observed between VDR polymorphisms and MI phenotypes (P=0.460). However, the results of the casewise multiple regression analysis indicated that the ApaI genotypes accounted for 18% of injury severity (P=0.002). Therefore, while the BsmI and FokI polymorphisms did not appear to be associated with the severity or incidence of MI, the ApaI genotypes may have influenced the severity of muscle injury in top‑level football players.
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May-2015
Volume 9 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Massidda M, Corrias L, Bachis V, Cugia P, Piras F, Scorcu M and Calò CM: Vitamin D receptor gene polymorphisms and musculoskeletal injuries in professional football players. Exp Ther Med 9: 1974-1978, 2015
APA
Massidda, M., Corrias, L., Bachis, V., Cugia, P., Piras, F., Scorcu, M., & Calò, C.M. (2015). Vitamin D receptor gene polymorphisms and musculoskeletal injuries in professional football players. Experimental and Therapeutic Medicine, 9, 1974-1978. https://doi.org/10.3892/etm.2015.2364
MLA
Massidda, M., Corrias, L., Bachis, V., Cugia, P., Piras, F., Scorcu, M., Calò, C. M."Vitamin D receptor gene polymorphisms and musculoskeletal injuries in professional football players". Experimental and Therapeutic Medicine 9.5 (2015): 1974-1978.
Chicago
Massidda, M., Corrias, L., Bachis, V., Cugia, P., Piras, F., Scorcu, M., Calò, C. M."Vitamin D receptor gene polymorphisms and musculoskeletal injuries in professional football players". Experimental and Therapeutic Medicine 9, no. 5 (2015): 1974-1978. https://doi.org/10.3892/etm.2015.2364