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Article

Correlation of high‑sensitivity C‑reactive protein and carotid plaques with coronary artery disease in elderly patients

  • Authors:
    • Yanhong Liang
    • Yuanping Hou
    • Hongyu Niu
    • Mei Lu
    • Lei Xue
    • Qianmei Sun
  • View Affiliations / Copyright

    Affiliations: Department of Geriatric Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China
  • Pages: 275-278
    |
    Published online on: May 11, 2015
       https://doi.org/10.3892/etm.2015.2486
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Abstract

The aim of this study was to explore the correlation of high‑sensitivity C‑reactive protein (hs‑CRP) and carotid plaques with the severity of coronary artery disease (CAD). A total of 140 patients with angina who underwent coronary angiography were selected and divided into a single‑vessel disease group (n=11), double‑vessel disease group (n=18), multi‑vessel disease group (n=71) and control group (n=40). Color Doppler ultrasound was applied to measure the intima‑media thickness (IMT) of the common carotid artery (CCA) and carotid bifurcation, and to record the location and number of carotid plaques. The serum hs‑CRP level was also determined. Compared with the control and single‑vessel disease groups, the multi‑vessel disease group showed significantly higher IMT of the CCA (P<0.05). The serum hs‑CRP level was highest in the multi‑vessel disease group (P<0.01). The hs‑CRP level and carotid plaque characteristics were found to correlate closely with the severity of CAD. Therefore, they may be used to improve the prediction of CAD severity in elderly patients.
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Copy and paste a formatted citation
Spandidos Publications style
Liang Y, Hou Y, Niu H, Lu M, Xue L and Sun Q: Correlation of high‑sensitivity C‑reactive protein and carotid plaques with coronary artery disease in elderly patients. Exp Ther Med 10: 275-278, 2015.
APA
Liang, Y., Hou, Y., Niu, H., Lu, M., Xue, L., & Sun, Q. (2015). Correlation of high‑sensitivity C‑reactive protein and carotid plaques with coronary artery disease in elderly patients. Experimental and Therapeutic Medicine, 10, 275-278. https://doi.org/10.3892/etm.2015.2486
MLA
Liang, Y., Hou, Y., Niu, H., Lu, M., Xue, L., Sun, Q."Correlation of high‑sensitivity C‑reactive protein and carotid plaques with coronary artery disease in elderly patients". Experimental and Therapeutic Medicine 10.1 (2015): 275-278.
Chicago
Liang, Y., Hou, Y., Niu, H., Lu, M., Xue, L., Sun, Q."Correlation of high‑sensitivity C‑reactive protein and carotid plaques with coronary artery disease in elderly patients". Experimental and Therapeutic Medicine 10, no. 1 (2015): 275-278. https://doi.org/10.3892/etm.2015.2486
Copy and paste a formatted citation
x
Spandidos Publications style
Liang Y, Hou Y, Niu H, Lu M, Xue L and Sun Q: Correlation of high‑sensitivity C‑reactive protein and carotid plaques with coronary artery disease in elderly patients. Exp Ther Med 10: 275-278, 2015.
APA
Liang, Y., Hou, Y., Niu, H., Lu, M., Xue, L., & Sun, Q. (2015). Correlation of high‑sensitivity C‑reactive protein and carotid plaques with coronary artery disease in elderly patients. Experimental and Therapeutic Medicine, 10, 275-278. https://doi.org/10.3892/etm.2015.2486
MLA
Liang, Y., Hou, Y., Niu, H., Lu, M., Xue, L., Sun, Q."Correlation of high‑sensitivity C‑reactive protein and carotid plaques with coronary artery disease in elderly patients". Experimental and Therapeutic Medicine 10.1 (2015): 275-278.
Chicago
Liang, Y., Hou, Y., Niu, H., Lu, M., Xue, L., Sun, Q."Correlation of high‑sensitivity C‑reactive protein and carotid plaques with coronary artery disease in elderly patients". Experimental and Therapeutic Medicine 10, no. 1 (2015): 275-278. https://doi.org/10.3892/etm.2015.2486
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