Clinical efficacy of ʻSpleen‑kidney‑careʼ Yiqi Huayu and Jiangzhuo traditional Chinese medicine for the treatment of patients with diabetic nephropathy

  • Authors:
    • Hong Liu
    • Jin Zheng
    • Rong‑Heng Li
  • View Affiliations

  • Published online on: July 7, 2015     https://doi.org/10.3892/etm.2015.2627
  • Pages: 1096-1102
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Abstract

The aim of the present study was to investigate the effect of the traditional Chinese medicine (TCM), ʻSpleen‑kidney‑careʼ Yiqi Huayu and Jiangzhuo decoction (SKC‑YJ), as an adjuvant therapy in diabetic nephropathy (DN) treatment. In total, 72 patients with DN were randomly divided into control (n=54) and experimental (n=18) groups, with the latter administered SKC‑YJ treatment. Indicators for determining the condition of the patients included the levels of proteinuria, blood glucose, glycosylated hemoglobin, blood lipids, blood viscosity and C‑reactive protein, which were used to analyze the treatment protocols for DN. Following SKC‑YJ treatment, the urinary albumin excretion rate, fasting blood glucose, 2 h‑postprandial blood glucose, glycosylated hemoglobin, triglyceride, total cholesterol, blood viscosity, fibrinogen and C‑reactive protein levels were detected in the two groups, and were all demonstrated to decrease significantly following treatment with SKC‑YJ. Furthermore, the results revealed that SKC‑YJ treatment exhibited no significant side‑effects on the blood, liver and renal functions or gastrointestinal reactions. By contrast, SKC‑YJ improved the symptoms of nausea, vomiting and diarrhea in the patients with DN, while showing no allergic reaction during the observation period. Therefore, SKC‑YJ treatment was shown to significantly improve the clinical efficacy of DN treatment, illustrating novel roles for TCM in DN treatment.
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September-2015
Volume 10 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Liu H, Zheng J and Li RH: Clinical efficacy of ʻSpleen‑kidney‑careʼ Yiqi Huayu and Jiangzhuo traditional Chinese medicine for the treatment of patients with diabetic nephropathy. Exp Ther Med 10: 1096-1102, 2015
APA
Liu, H., Zheng, J., & Li, R. (2015). Clinical efficacy of ʻSpleen‑kidney‑careʼ Yiqi Huayu and Jiangzhuo traditional Chinese medicine for the treatment of patients with diabetic nephropathy. Experimental and Therapeutic Medicine, 10, 1096-1102. https://doi.org/10.3892/etm.2015.2627
MLA
Liu, H., Zheng, J., Li, R."Clinical efficacy of ʻSpleen‑kidney‑careʼ Yiqi Huayu and Jiangzhuo traditional Chinese medicine for the treatment of patients with diabetic nephropathy". Experimental and Therapeutic Medicine 10.3 (2015): 1096-1102.
Chicago
Liu, H., Zheng, J., Li, R."Clinical efficacy of ʻSpleen‑kidney‑careʼ Yiqi Huayu and Jiangzhuo traditional Chinese medicine for the treatment of patients with diabetic nephropathy". Experimental and Therapeutic Medicine 10, no. 3 (2015): 1096-1102. https://doi.org/10.3892/etm.2015.2627