Successful treatment of refractory chronic hand eczema with calcipotriol/betamethasone ointment: A report of three cases

Yang,Min; Chang,Jian‑Min

doi:10.3892/etm.2015.2729

Successful treatment of refractory chronic hand eczema with calcipotriol/betamethasone ointment: A report of three cases

Authors:
- Min Yang
- Jian‑Min Chang
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Affiliations: Department of Dermatology, Beijing Hospital, Beijing 100730, P.R. China
Published online on: September 4, 2015 https://doi.org/10.3892/etm.2015.2729
Pages: 1943-1946

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Abstract

Chronic hand eczema (CHE) is a common skin disorder with frequent relapses, and its treatment comprises a challenge due to its uncertain etiology. In particular, certain cases of CHE exhibiting severe keratinization have a very poor response to various treatments. The Daivobet ointment, a complex product comprising calcipotriol and betamethasone, has been successfully used for the treatment of patients with plaque‑type psoriasis for ~10 years; however, there are few reports on the effect of the ointment on other skin disorders of abnormal keratinization, such as eczema. The present study reported 3 cases of refractory hyperkeratotic eczema of the hand that did not respond to several treatments, but responded well to topical Daivobet treatment.

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