Pediatric sinonasal rhabdomyosarcoma: A case report

Bostanci,Asli; Asik,Mehmet; Turhan,Murat

doi:10.3892/etm.2015.2839

December-2015 Volume 10 Issue 6

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December-2015 Volume 10 Issue 6

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Case Report

Pediatric sinonasal rhabdomyosarcoma: A case report

Authors:
- Asli Bostanci
- Mehmet Asik
- Murat Turhan
View Affiliations / Copyright

Affiliations: Department of Otolaryngology, Head and Neck Surgery, Akdeniz University School of Medicine, Antalya 07070, Turkey
Pages: 2444-2446
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Published online on: October 30, 2015

https://doi.org/10.3892/etm.2015.2839
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Abstract

Pediatric sinonasal rhabdomyosarcoma (PSR) is a rare condition, with a limited number of previously reported cases. It is an aggressive malignancy associated with poor outcomes, and no consensus has been reached on the optimal therapeutic strategy. The present study reported the case of embryonal PSR in a 2‑year old girl, presenting with unilateral nasal obstruction and a polypoid mass protruding from the left nasal cavity. The pediatric patient was initially treated with surgical resection, followed by adjuvant chemotherapy containing vincristine (1.5 mg/m2, weekly) and actinomycin‑D (1.5 mg/m2, three times weekly). On the 10th month of follow‑up, tumor recurrence was detected and a salvage surgery was performed, while the same chemotherapy regimen was resumed. Following the first cycle of chemotherapy, the patient developed a fungal bronchopneumonia and succumbed due to disease progression, acute respiratory distress syndrome and septic shock 12 months after diagnosis.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Pediatric sinonasal rhabdomyosarcoma: A case report

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Abstract

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