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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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December-2015 Volume 10 Issue 6

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Article Open Access

Novel antiepileptic drug lacosamide exerts neuroprotective effects by decreasing glial activation in the hippocampus of a gerbil model of ischemic stroke

Ji Yun Ahn, Bing Chun Yan, Joon Ha Park, Ji Hyeon Ahn, Dae Hwan Lee, In Hye Kim, Jeong‑Hwi Cho, Bai Hui Chen, Jae‑Chul Lee, Young Shin Cho, Myoung Chul Shin, Jun Hwi Cho, Seongkweon Hong, Moo‑Ho Won, Sung Koo Kim
Pages: 2007-2014
Published online on: 13 October 2015

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Article Open Access

Effects of acute exercise on liver function and blood redox status in heavy drinkers

Kalliopi Georgakouli, Eirini Manthou, Ioannis G. Fatouros, Chariklia K. Deli, Demetrios A. Spandidos, Aristidis M. Tsatsakis, Demetrios Kouretas, Yiannis Koutedakis, Yannis Theodorakis, Athanasios Z. Jamurtas
Pages: 2015-2022
Published online on: 13 October 2015

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Article Open Access

Surgical methods and efficacies for cervicothoracolumbar spinal schwannoma

Qiang Deng, Zheng Tian, Weibin Sheng, Hailong Guo, Mai Er Dan
Pages: 2023-2028
Published online on: 15 October 2015

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Article Open Access

Effect of peritoneal lavage with ulinastatin on the expression of NF-κB and TNF-α in multiple organs of rats with severe acute pancreatitis

Cong Feng, Bei Li, Li‑Li Wang, Li Chen, Xuan Zhou, Fa‑Qin Lv, Tan‑Shi Li
Pages: 2029-2034
Published online on: 15 October 2015

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Article Open Access

Establishment of a rat model for osteoarthritis resulting from anterior cruciate ligament rupture and its significance

Xiao Ouyang, Jian Wang, Shi Dong Hong, Feng Xin, Lin Wang, Xiao Wei Yang, Jing Rong Wang, Li Ming Wang, Bo Wei, Qing Wang, Wei Ding Cui
Pages: 2035-2038
Published online on: 25 September 2015

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Article Open Access

Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis

Shi‑Bin Guo, Zhi‑Jun Duan, Qiu‑Ming Wang, Qin Zhou, Qing Li, Xiao‑Yu Sun
Pages: 2039-2046
Published online on: 22 October 2015

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Article Open Access

Advantages of a dual-color fluorescence-tracing glioma orthotopic implantation model: Detecting tumor location, angiogenesis, cellular fusion and the tumor microenvironment

Yuntian Shen, Quanbin Zhang, Jinshi Zhang, Zhaohui Lu, Aidong Wang, Xifeng Fei, Xingliang Dai, Jinding Wu, Zhimin Wang, Yaodong Zhao, Ye Tian, Jun Dong, Qing Lan, Qiang Huang
Pages: 2047-2054
Published online on: 22 October 2015

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Article Open Access

Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by stimulating aquaporin-5 expression

Xuejun Chen, Chunxia Zhou, Chunxiao Yan, Jiong Ma, Wei Zheng
Pages: 2055-2062
Published online on: 26 October 2015

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Article Open Access

Neuroprotective effects of Rhizoma Dioscoreae polysaccharides against neuronal apoptosis induced by in vitro hypoxia

Qin Xiang, Wen‑Yun Zhou, Wei‑Xu Hu, Zhu Wen, Dan He, Xiao‑Mu Wu, Hui‑Ping Wei, Wen‑Ding Wang, Guo‑Zhu Hu
Pages: 2063-2070
Published online on: 20 October 2015

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Article Open Access

Isolation and characterization of side population cells from the human ovarian cancer cell line SK-OV-3

Zhengyi Ruan, Jianhua Liu, Yanping Kuang
Pages: 2071-2078
Published online on: 30 October 2015

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Article Open Access

Effect of 131I ‘clear residual thyroid tissue’ after surgery on the function of parathyroid gland in differentiated thyroid cancer

Zhi‑Hua Zhao, Feng‑Qi Li, Jian‑Kui Han, Xian‑Jun Li
Pages: 2079-2082
Published online on: 19 October 2015

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Article Open Access

Simultaneous integrated dose reduction intensity-modulated radiotherapy applied to an elective nodal area of limited-stage small-cell lung cancer

Zhiyan Liu, Weishuai Liu, Kai Ji, Ping Wang, Xin Wang, Lujun Zhao
Pages: 2083-2087
Published online on: 30 October 2015

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Article Open Access

E-cadherin expression in a rat model of acute pancreatitis

Weihong Yuan, Qi Pan, Guochang Chen, Jun Yan, Jiazeng Xia, Yigang Chen
Pages: 2088-2092
Published online on: 05 October 2015

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Article Open Access

Impact of collection, isolation and storage methodology of circulating microvesicles on flow cytometric analysis

Fancong Kong, Liming Zhang, Hongxiang Wang, Guolin Yuan, Anyuan Guo, Qiubai Li, Zhichao Chen
Pages: 2093-2101
Published online on: 25 September 2015

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Article Open Access

In vitro gene expression profile of bovine peripheral blood mononuclear cells in early Mycobacterium bovis infection

Yafen Cheng, Chung‑Hsi Chou, Hsiang‑Jung Tsai
Pages: 2102-2118
Published online on: 19 October 2015

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Article Open Access

Enhanced expression of glucose‑regulated protein 78 correlates with malondialdehyde levels during the formation of liver cirrhosis in rats

Yun Zhang, Huiying Zhang, Zhongfu Zhao, Minli Lv, Jiantao Jia, Lili Zhang, Xiaoxia Tian, Yunxia Chen, Baohong Li, Mingshe Liu, Dewu Han, Cheng Ji
Pages: 2119-2125
Published online on: 01 October 2015

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Article Open Access

The use of fluorine-18 fluorodeoxyglucose positron emission tomography for imaging human motor neuronal activation in the brain

Kisoo Pahk, Kun‑Woo Park, Sung Bom Pyun, Jae Sung Lee, Sungeun Kim, Jae Gol Choe
Pages: 2126-2130
Published online on: 06 October 2015

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Article Open Access

Mesenchymal stem cells attenuate acute ischemia-reperfusion injury in a rat model

Weifeng Lu, Yi Si, Jianyong Ding, Xiaoli Chen, Xiangman Zhang, Zhihui Dong, Weiguo Fu
Pages: 2131-2137
Published online on: 15 October 2015

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Article Open Access

Expression levels of vascular endothelial cell growth factor and microRNA‑210 are increased in medulloblastoma and metastatic medulloblastoma

Yong Gao, Puxian Li, Zhenrui Liu, Xingtao Diao, Chunyun Song
Pages: 2138-2144
Published online on: 16 October 2015

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Article Open Access

Glycated albumin is an optimal biomarker for gestational diabetes mellitus

Yaping Huang, Yongwei Hu, Yu Ma, Guangyong Ye
Pages: 2145-2149
Published online on: 16 October 2015

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Article

Topographic analysis of the mandibular symphysis in a normal occlusion population using cone-beam computed tomography

Ji‑Eun Lee, Yoon‑Jin Lee, Seong‑Ho Jin, Yoonji Kim, Yoon‑Ah Kook, Youngkyung Ko, Jun‑Beom Park
Pages: 2150-2156
Published online on: 02 November 2015

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Article

Association between colon diverticula and hemoglobin, triglyceride and uric acid levels

Minoru Tomizawa, Fuminobu Shinozaki, Rumiko Hasegawa, Yoshinori Shirai, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Pages: 2157-2160
Published online on: 15 October 2015

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Article

Mechanisms of human amniotic epithelial cell transplantation in treating stage III pressure ulcer in a rat model

Aiting Zhou, Xilan Zheng, Limei Yu, Mingtao Quan, Xing Shao, Zhixia Jiang
Pages: 2161-2168
Published online on: 25 September 2015

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Article

Comparative study of HPV16 integration in cervical lesions between ethnicities with high and low rates of infection with high‑risk HPV and the correlation between integration rate and cervical neoplasia

Lili Han, Tuerxunayi Maimaitiming, Sulaiya Husaiyin, Lin Wang, Kunduozi Wusainahong, Chunhua Ma, Mayinuer Niyazi
Pages: 2169-2174
Published online on: 10 September 2015

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Article

Clinical value of plasma B‑type natriuretic peptide assay in pediatric pneumonia accompanied by heart failure

Dan Hu, Yang Liu, Huixian Tao, Jinping Gao
Pages: 2175-2179
Published online on: 01 October 2015

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Article

Comparative efficacy and cost effectiveness of splenectomy and thrombopoietin prior to peginterferon and ribavirin therapy with compensatory cirrhosis associated with hepatitis C and thrombocytopenia

Bing Li, Ying Jie Ji, Qing Shao, Zhenyu Zhu, Dong Ji, Fan Li, Guofeng Chen
Pages: 2180-2186
Published online on: 23 October 2015

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Article

Use of a correlation analysis model in the optimization of intensity-modulated radiotherapy of prostate cancer

Xiadong Li, Qinghua Deng, Shenglin Ma, Ke Zhang, Zhibing Wu, Jianjun Lai, Rongjun Tang, Yao Ren, Jiahao Wang, Lixia Xu
Pages: 2187-2193
Published online on: 26 October 2015

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Case Report

Bladder exstrophy-epispadias complex with adenocarcinoma in an adult patient: A case report

Wei Xiong, Ran Peng, Liang Zhu, Zhaohui Zhong
Pages: 2194-2196
Published online on: 13 October 2015

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Article

Pharmacological preconditioning and postconditioning with nicorandil attenuates ischemia/reperfusion‑induced myocardial necrosis and apoptosis in hypercholesterolemic rats

Wenna Li, Nan Wu, Wenqi Shu, Dalin Jia, Pengyu Jia
Pages: 2197-2205
Published online on: 01 October 2015

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Article

Naringenin attenuates pressure overload-induced cardiac hypertrophy

Ning Zhang, Zheng Yang, Yuan Yuan, Fangfang Li, Yuan Liu, Zhenguo Ma, Haihan Liao, Zhouyan Bian, Yao Zhang, Heng Zhou, Wei Deng, Mengqiao Zhou, Qizhu Tang
Pages: 2206-2212
Published online on: 19 October 2015

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Article

A rare case of juvenile localised scleroderma with intra-oral and dental involvement

Peng Wang, Wei Guo, Shutai Liu
Pages: 2213-2215
Published online on: 12 October 2015

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Article

Cell sheet-engineered bones used for the reconstruction of mandibular defects in an animal model

Chunhua Du, Chao Yao, Ningyi Li, Shuangyi Wang, Yuanyong Feng, Xuecai Yang
Pages: 2216-2220
Published online on: 30 October 2015

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Case Report

Adult cervicomedullary pilocytic astrocytoma: A case report

Yaodong Zhao, Lijin Feng, Qing Wei, Liang Gao
Pages: 2221-2223
Published online on: 23 October 2015

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Article

Downregulation of telomerase maintenance-related ACD expression in patients undergoing immunosuppresive therapy following kidney transplantation

Agnieszka Witkowska, Barbara Strzalka‑Mrozik, Aleksander Owczarek, Joanna Gola, Urszula Mazurek, Wladyslaw Grzeszczak, Janusz Gumprecht
Pages: 2224-2230
Published online on: 02 October 2015

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Article

Epigallocatechin‑3‑gallate‑induced inhibition of interleukin‑6 release and adjustment of the regulatory T/T helper 17 cell balance in the treatment of colitis in mice

Zhenglei Xu, Cheng Wei, Ru Zhang, Jun Yao, Dinguo Zhang, Lisheng Wang
Pages: 2231-2238
Published online on: 23 October 2015

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Article

Solitaire AB stent‑assisted coiling embolization for the treatment of ruptured very small intracranial aneurysms

Jifang Zhang, Donghai Wang, Xingang Li
Pages: 2239-2244
Published online on: 23 October 2015

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Article

microRNA and gene networks in human laryngeal cancer

Fengyu Zhang, Zhiwen Xu, Kunhao Wang, Linlin Sun, Genghe Liu, Baixu Han
Pages: 2245-2252
Published online on: 23 October 2015

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Article

Peritoneal dialysis treatment for severe lupus nephritis patients complicated with essential organ dysfunction

Yan Zhou, Yusheng Yu, Zheng Tang, Shijun Li, Weixin Hu, Chunlei Luo, Zhihong Liu
Pages: 2253-2258
Published online on: 14 October 2015

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Article

Eriodictyol, a plant flavonoid, attenuates LPS‑induced acute lung injury through its antioxidative and anti‑inflammatory activity

Guang‑Fa Zhu, Hong‑Juan Guo, Yan Huang, Chun‑Ting Wu, Xiang‑Feng Zhang
Pages: 2259-2266
Published online on: 23 October 2015

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Article

Caspase-8 polymorphisms and risk of oral squamous cell carcinoma

Yi Tang, Yang Liu, Wei Zhao, Tao Yu, Haiyang Yu
Pages: 2267-2276
Published online on: 26 October 2015

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Article

Hydrogen-rich saline attenuates chemotherapy-induced ovarian injury via regulation of oxidative stress

Xiaoyin Meng, Hongguang Chen, Guolin Wang, Yonghao Yu, Keliang Xie
Pages: 2277-2282
Published online on: 05 October 2015

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Article

Construction and identification of an RNA interference lentiviral vector targeting the mouse TNF-α gene

Jibo Wang, Hongda Liang, Yingjie Zhao, Xiangping Liu, Kun Yang, Aihua Sui
Pages: 2283-2288
Published online on: 19 October 2015

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Article

Antiproliferative effect and characterization of a novel antifungal peptide derived from human Chromogranin A

Rui‑Fang Li, Ya‑Li Lu, Yan‑Bo Lu, Hui‑Ru Zhang, Liang Huang, Yanli Yin, Lin Zhang, Shuai Liu, Zhifang Lu, Yanan Sun
Pages: 2289-2294
Published online on: 30 October 2015

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Article

Long-term remission induced by low-dose rituximab for relapsed and refractory thrombotic thrombocytopenic purpura: A report of two cases

Hong‑Yan Tong, Li Ye, Xing‑Nong Ye, De‑Min Lu, Ying Li
Pages: 2295-2298
Published online on: 14 October 2015

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Article

Clinical and histological predictive risk factors of atrial fibrillation in patients undergoing open-heart surgery

Grigore Tinica, Veronica Mocanu, Florin Zugun‑Eloae, Doina Butcovan
Pages: 2299-2304
Published online on: 12 October 2015

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Article

Anticancer activity of bicalutamide-loaded PLGA nanoparticles in prostate cancers

Jun Guo, Shu‑Hong Wu, Wei‑Guo Ren, Xin‑Li Wang, Ai‑Qing Yang
Pages: 2305-2310
Published online on: 14 October 2015

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Article

Effect of changes in sympathovagal balance on the accuracy of heart rate variability obtained from photoplethysmography

Xiang Chen, Yuan‑Yuan Huang, Feng Yun, Tian‑Jun Chen, Jin Li
Pages: 2311-2318
Published online on: 02 October 2015

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Article

BET protein inhibition mitigates acute myocardial infarction damage in rats via the TLR4/TRAF6/NF-κB pathway

Yangli Sun, Jie Huang, Kunpeng Song
Pages: 2319-2324
Published online on: 08 October 2015

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Article

Ultrastructural identification of telocytes in the muscularis of chicken ileum

Ping Yang, Ya'an Liu, Nisar Ahmed, Shakeeb Ullah, Yi Liu, Qiusheng Chen
Pages: 2325-2330
Published online on: 30 October 2015

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Article

Low‑molecular‑weight heparin and intermittent pneumatic compression for thromboprophylaxis in critical patients

Bing Wan, Hai‑Yan Fu, Jiang‑Tao Yin, Guo‑Qing Ren
Pages: 2331-2336
Published online on: 13 October 2015

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Article

Epidemiology and clinical features of segmental/lobar pattern Mycoplasma pneumoniae pneumonia: A ten-year retrospective clinical study

Jian Gao, Baozhu Yue, Haitao Li, Rong Chen, Chunlian Wu, Mili Xiao
Pages: 2337-2344
Published online on: 19 October 2015

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Article

Effect of low-dose diuretics on the level of serum cystatin C and prognosis in patients with asymptomatic chronic heart failure

Yuan Zhang, Yanming Li, Guanchang Cheng
Pages: 2345-2350
Published online on: 30 October 2015

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Article

Protective effects of paeoniflorin against FasL‑induced apoptosis of intervertebral disc annulus fibrosus cells via Fas‑FasL signalling pathway

Shao‑Qing Chen, Jian‑Ping Lin, Qi‑Kai Zheng, Shui‑Jin Chen, Ming Li, Xian‑Zhao Lin, Shi‑Zhong Wang
Pages: 2351-2355
Published online on: 25 September 2015

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Article

Effects of paternal cadmium exposure on the sperm quality of male rats and the neurobehavioral system of their offspring

Xiaoguo Zhao, Zhenzhen Cheng, Yi Zhu, Shan Li, Liang Zhang, Yunbo Luo
Pages: 2356-2360
Published online on: 25 September 2015

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Article

Analysis of mutations of MDR3 exons 9 and 23 in infants with parenteral nutrition-associated cholestasis

Xiu‑Fang Yang, Guo‑Sheng Liu, Min‑Xu Li
Pages: 2361-2365
Published online on: 14 October 2015

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Article

Evaluation of extrahepatic collateral arteries in hepatocellular carcinoma in three independent groups in a single center

Yilin Zhao, Zhuting Fang, Jianjun Luo, Qingxin Liu, Gang Xu, Heng Pan, Wei Wei, Zhiping Yan
Pages: 2366-2374
Published online on: 22 October 2015

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Article

Long-term outcomes of rotational atherectomy in coronary bifurcation lesions

Yuxiang Dai, Atsutoshi Takagi, Hakuoh Konishi, Tetsuro Miyazaki, Hiroshi Masuda, Kazunori Shimada, Katsumi Miyauchi, Hiroyuki Daida
Pages: 2375-2383
Published online on: 19 October 2015

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Article

Chronic nerve injury-induced Mas receptor expression in dorsal root ganglion neurons alleviates neuropathic pain

Yuanting Zhao, Yue Qin, Tuanjiang Liu, Dingjun Hao
Pages: 2384-2388
Published online on: 15 October 2015

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Article

Effects of thymosin β4 on a rat model of severe acute pancreatitis

Xiaobo He, Jia Yu, Wenyi Guo, Teng Zuo, Qiao Shi, Kailiang Zhao, Weixing Wang
Pages: 2389-2395
Published online on: 14 October 2015

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Article

Correlation analysis of severe aplastic anemia immunosuppressive therapy and human leukocyte antigen alleles in pediatric patients

Ru‑Ting Fu, Hong‑Man Xue, Bi‑Hong Zhang, Jian Wang, Shao‑Fen Lin, Chun Chen
Pages: 2396-2402
Published online on: 15 October 2015

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Article

In vitro analysis of the role of the mitochondrial apoptosis pathway in CSBE therapy against human gastric cancer

Yu‑Bin Ji, Lei Yu
Pages: 2403-2409
Published online on: 25 September 2015

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Article

Cardiac shockwave therapy improves myocardial function in patients with refractory coronary artery disease by promoting VEGF and IL-8 secretion to mediate the proliferation of endothelial progenitor cells

Hong‑Yan Cai, Lin Li, Tao Guo, Yu Wang, Tie‑Kun Ma, Jian‑Ming Xiao, Ling Zhao, Yin Fang, Ping Yang, Hu Zhao
Pages: 2410-2416
Published online on: 20 October 2015

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Article

Neonatal capsaicin treatment in rats induces chronic hyperthermia resulting in infectious disease

Keun‑Yeong Jeong, Hwan Mook Kim
Pages: 2417-2423
Published online on: 23 October 2015

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Article

Use of high-resolution 3.0-T magnetic resonance imaging to characterize atherosclerotic plaques in patients with cerebral infarction

Peng Xu, Lulu Lv, Shaodong Li, Haitao Ge, Yutao Rong, Chunfeng Hu, Kai Xu
Pages: 2424-2428
Published online on: 19 October 2015

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Case Report

Airway loss during inhalation induction of anesthesia with sevoflurane in a pediatric patient with laryngeal papillomatosis: A case report

Xiao Hu, Xia Shen
Pages: 2429-2431
Published online on: 15 October 2015

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Novel keratin 5 mutation in a family with epidermolysis bullosa simplex

Jiajia Gao, Xuebin Wang, Fang Zheng, Sufang Dong, Xueping Qiu
Pages: 2432-2436
Published online on: 16 October 2015

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Interleukin-2 is upregulated in patients with a prolapsed lumbar intervertebral disc and modulates cell proliferation, apoptosis and extracellular matrix metabolism of human nucleus pulposus cells

Zhirong Wang, Genlin Wang, Xuesong Zhu, Dechun Geng, Huilin Yang
Pages: 2437-2443
Published online on: 16 October 2015

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Pediatric sinonasal rhabdomyosarcoma: A case report

Asli Bostanci, Mehmet Asik, Murat Turhan
Pages: 2444-2446
Published online on: 30 October 2015

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[Corrigendum] Association between Parkinson's disease and G2019S and R1441C mutations of the LRRK2 gene

Xiao‑Xia Li, Qin Luo, Huan Xia, Xin‑Ling Yang
Pages: 2447-2447
Published online on: 26 October 2015

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October-2026 Volume 32 Issue 4

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Promoting expertise knowledge sharing in paediatric virology: An update (Review)

Ioannis N. Mammas, Anna Kramvis, Anastasia Stouraiti, Tina Dalianis, Patra Koletsi, Georgia Papaioannou, Alexia Papatheodoropoulou, Chryssie Koutsaftiki, Paraskevi Korovessi, Simon B. Drysdale, Maria Theodoridou, Demetrios A. Spandidos
Article Number: 293
Published online on: 07 September 2026

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ACT001 suppresses ox‑LDL‑mediated macrophage ferroptosis via activating the NRF2 pathway: An in vitro mechanistic study relevant to atherosclerosis

Yangyang Tao, Yuwu Chen, Yonghou Zhao, Jianbo Cai
Article Number: 292
Published online on: 07 September 2026

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From mitochondria to innate immunity: The mtDNA‑driven cGAS/STING‑NLRP3 cascade and its therapeutic implications in neurodegenerative diseases (Review)

Hui Liu, Yao Zhang, Ziliang Zhuo, Wei Zhong, Manyun Yan, Zhongbo Zhao
Article Number: 291
Published online on: 04 September 2026

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Active abdominal compression‑decompression cardiopulmonary resuscitation attenuates neuroinflammation associated with TLR4/NF‑κB signaling in a rat model of cardiac arrest

Xiaopeng Liu, Xiaoqing Yang, Yifan Huang, Xinyuan Kong, Jiankai Gao, Hongyu Wang, Sisen Zhang
Article Number: 290
Published online on: 04 September 2026

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ASF1A: A versatile histone chaperone bridging chromatin dynamics, disease mechanisms and clinical potential (Review)

Jun Yin, Xiaojian Zhuo, Lihui Wen, Xianmin Wang, Tongyong Luo, Qingsong Wang
Article Number: 289
Published online on: 02 September 2026

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Preventive administration of verapamil attenuates dextran sulfate sodium‑induced colitis in mice

Natsuki Ota, Keisuke Sato, Ryosuke Tatsunami
Article Number: 288
Published online on: 02 September 2026

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Gut microbiome dynamics in acute infectious diarrhea: A conceptual framework from acute dysbiosis toward precision restoration (Review)

Cong Yuan, Jiale Tong, Weiwei Qian, Qian He
Article Number: 287
Published online on: 02 September 2026

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Mapping and anatomo‑surgical techniques for language preservation in brain tumours (Review)

Xiaoyuan Liu, Jia Ouyang, Jiangfei Wang
Article Number: 286
Published online on: 02 September 2026

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[Corrigendum] Circular RNA expression profiles significantly altered in UVA‑irradiated human dermal fibroblasts

Mengbi Lin, Yue Zheng, Qian Li, Yufang Liu, Qingfang Xu, Yuying Li, Wei Lai
Article Number: 285
Published online on: 01 September 2026

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Generation and evaluation of multimers of anti C‑reactive protein Nb and alkaline phosphatase based on three self‑assembly peptides

Honghe Li, Chenchen Zhou, Xiaomei Zhang, Ning Ding, Qiong Wu, Junming Li, Yang Zheng, Xuejun Hu
Article Number: 284
Published online on: 28 August 2026

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New insights into diagnostic values and mechanisms of ferroptosis associated with immune infiltration in diabetic kidney disease

Ying Tan, Zihui Liu, Siyuan Song, Lingling Zhu, Yun She, Xiqiao Zhou, Jiangyi Yu, Qianhua Yan
Article Number: 283
Published online on: 28 August 2026

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Biological mechanisms underlying the effects of low‑magnitude mechanical stress in osteoporosis (Review)

Zhi Liu, Dan Han, Yanfei Wang, Hongfan Li, Xuedong Pei, Zhijing Song
Article Number: 282
Published online on: 28 August 2026

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Expression of Concern Open Access

[Expression of Concern] Transformation of nomifensine using ionizing radiation and exploration of its anticancer effects in MCF‑7 cells

Seong Hee Kang, Dong-Ho Bak, Byung Yeoup Chung, Hyoung-Woo Bai
Article Number: 281
Published online on: 21 August 2026

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Retrospective study of infusion‑related reactions in subcutaneous daratumumab administration in Japan

Yoko Ino, Kazuhide Tanaka, Fuka Ito, Nao Yamagishi, Futa Takemura, Masahiro Yasuda, Senji Kasahara
Article Number: 280
Published online on: 20 August 2026

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[Retracted] Combined effects of Lenvatinib and iodine‑131 on cell apoptosis in nasopharyngeal carcinoma through inducing endoplasmic reticulum stress

Guoyu Wang, Juhua Zhuang, Jing Ni, Ying Ye, Saifei He, Wei Xiai
Article Number: 279
Published online on: 17 August 2026

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PDK1/AKT signaling is involved in the anti‑tumor effect of gramine and cisplatin chemoresistance in ovarian cancer cells

Haiyan Wang, Ruiming Zheng, Bujun Wang, Sumiao Hong, Hongxia Chen
Article Number: 278
Published online on: 14 August 2026

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Integrating clinical outcomes with molecular simulations to guide the selection of non‑classical EGFR‑TKIs: A comprehensive analysis and development of treatment strategies

Fang Wei, Niu Niu, Chang Li, Ge Gao, Nan Li, Yan Wang
Article Number: 277
Published online on: 14 August 2026

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Case Report Open Access

Clinicopathological analysis of neuroendocrine carcinoma discovered incidentally in hemorrhoids: A case report and literature review

Bin Huang, Haiyan Zhou, Jianping Shi, Hongsheng Liu
Article Number: 276
Published online on: 12 August 2026

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Mechanism of microRNA‑30b‑5p enhancing the response of MDA‑MB‑231 cells to cisplatin by regulating RAP1B expression

Kewei Tang, Site Bai, Yajun Tong, Songjiang Liu, Leilan Yin, Ludi Ou, Qinghua Yin, Qiang Zhou
Article Number: 275
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Platelet‑rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors

Guilin Huang, Sha Hua, Tuanmin Yang, Jianbing Ma, Wenxing Yu, Xiujin Chen
Article Number: 274
Published online on: 12 August 2026

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Establishment of a novel asymmetric force degenerative lumbar scoliosis aging bipedal rat model

Jing Peng, Daigui Cao, Xu Zhou, Zhiwei Liu, Xinxing Wang, Anwei Zhang, Kai Shen
Article Number: 273
Published online on: 11 August 2026

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Case Report Open Access

Rapid diagnosis of Chlamydia psittaci pneumonia with pleural effusion using multiplex PCR‑based targeted next‑generation sequencing: A case report

Yang Jin, Liqun He, Jiankun Wang, Tao Ren, Hansheng Wang, Yue Wang
Article Number: 272
Published online on: 11 August 2026

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Sanguinarine chloride inducing ferroptosis and downregulating GPX4 expression in liver cancer: An integrated in silico, in vitro and in vivo study

Wen Ouyang, Jianxin Gao, Jing Liu, Lulu Qin, Bang Liu, Ying He, Dai Zhou
Article Number: 271
Published online on: 11 August 2026

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[Retracted] Activated protein C overexpression suppresses the pyroptosis of subarachnoid hemorrhage model cells by regulating the NLRP3 inflammasome pathway

Ai Yan, Xuyan Pan, Xianqiang Wen, Xiaohu Nie, Yuntao Li
Article Number: 270
Published online on: 10 August 2026

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RPLP0 drives diffuse large B‑cell lymphoma cell proliferation through reactive oxygen species‑dependent AKT/mTOR activation and inhibition of stress‑induced autophagy

Shanshan Wang, Xutao Yang, Rochelle Mcgowan, Belinda Hodge, Daniel Shan, Nicolas Miller, Jiahong Tang
Article Number: 269
Published online on: 07 August 2026

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Baseline neutrophil‑to‑lymphocyte ratio is not associated with chemotherapy‑induced nausea and vomiting in patients with breast cancer: A single‑center retrospective cohort study

Ruhper Cekin, Akif Dogan
Article Number: 268
Published online on: 07 August 2026

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Case Report Open Access

First case of neonatal bloodstream infection caused by Malassezia furfur in mainland China diagnosed via metagenomic next‑generation sequencing: A case report

Shanshan Gao, Lanlan Song, Qiujuan Feng, Yazhen Li, Huiqiang Liang, Ke Lei, Zheng Li, Peter Kisembo
Article Number: 267
Published online on: 06 August 2026

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Article

Comparative analysis of early and late recurrence rates in perianal fistula surgery

Ahmed Taha, Hi̇kmet Haşemi̇, Mutali̇p Ertuş, Bülent Özçeti̇n
Article Number: 266
Published online on: 06 August 2026

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Case Report

Cystic lymphangioma presenting as an ovarian mass in an adolescent: A case report and literature review

Rui Sun, Chun-Run Yang
Article Number: 265
Published online on: 05 August 2026

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Case Report

Postmenopausal osseous metaplasia of the endometrium: An uncommon histopathological entity: A case report

Emmanouela Aliki Almperi, Chrysoula Margioula Siarkou, Aristarchos Almperis, Nikoleta Dimitra Savvidou, Stamatios Petousis
Article Number: 264
Published online on: 05 August 2026

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Experimental evaluation of Curcuma Longa in docetaxel‑induced systemic toxicity: Functional hepatorenal and target organ analysis

Isabella Morais Tavares Huber, Emerson Luiz Botelho Lourenço, Salviano Tramontin Bellettini, Guilherme Donadel, João Francisco Velasquez Matumoto, Sandra Marisa Pelloso, Maria Dalva De Barros Carvalho, Stéfane Lele Rossoni, Mariana Morais Tavares Colferai, Diego Ricardo Colferai, Roberto Kenji Nakamura Cuman, Leonardo Garcia Velasquez
Article Number: 263
Published online on: 04 August 2026

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Case Report Open Access

Nasopharyngeal carcinoma with inguinal lymph node metastasis: A case report

Zhibin Lin, Shiliang Li, Donghong Yang, Tongyuan Deng, Haiwen Li, Yongcun Wang
Article Number: 262
Published online on: 04 August 2026

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Case Report

Adult‑onset focal nodular non‑exophytic nesidioblastosis mimicking insulinoma detected by endoscopic ultrasonography: A case report

Mesut Pekmez, Ümit Özçelik, Kemal Yandakçi, Alper Bilal Özkardeş
Article Number: 261
Published online on: 04 August 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑221 regulates cell activity and apoptosis in acute lymphoblastic leukemia via regulating PTEN

Lingyan Zhang, Zibin Bu, Juan Shen, Liping Shang, Yuanyuan Chen, Ping Zhang, Yan Wang
Article Number: 260
Published online on: 29 July 2026

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Predicting lower extremity deep vein thrombosis in elderly patients with hip fracture: A machine learning model with emphasis on diabetes as a key risk factor

Qian Song, Ping'an Shi, Peng Tian, Aijun Chao, Yinguang Zhang, Qiang Dong
Article Number: 259
Published online on: 29 July 2026

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Spatial specificity of Epstein‑Barr virus infection in gastric cancer: A 44‑case clinicopathological analysis

Xuming Wang, Longkuan Xu, Xiaozhen Yang, Xiaolu Yuan, Houliang Lu, Qiong Liu, Lijiang Liu
Article Number: 258
Published online on: 29 July 2026

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Crocin I delays cellular senescence potentially via modulating SIRT1/PKM2 expression to improve lactate homeostasis in vitro

Yicheng Fu, Zhiwei Ding, Yunchuang Chang, Chunxia Wu, Sanying Wang, Genxiang Mao, Huili Su
Article Number: 257
Published online on: 29 July 2026

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Case Report

Immune‑mediated liver injury caused by checkpoint inhibitors: A case series and review of the literature

Maria Kyrkasiadou, Anastasios Kyriazoglou, Ioannis Kotsantis, Panagiota Economopoulou, George Kavourakis, Roubini Zakopoulou, Maria Anastasiou, Anastasios Pantazopoulos, Anna Boulouta, Myrto Moutafi, Niki Gavrielatou, Periklis Foukas, Menelaos Samaras, Konstantinos Palialexis, Amanda Psyrri
Article Number: 256
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Reduced expression levels of the death‑associated protein kinase and E‑cadherin are correlated with the development of esophageal squamous cell carcinoma

Jianwen Zhai, Xiaogang Yang, Yanli Zhang, Qingbin Qi, Jigang Hu, Qiaomei Wang
Article Number: 255
Published online on: 27 July 2026

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Hematopoietic cell‑specific knockout Hspa9 impairs natural killer cell function and alters the Akt/mTOR axis in mice

Xiaokang Zeng, Jieyu Zhang, Caiying Liang, Jie Yao, Zuqiang Wu
Article Number: 254
Published online on: 24 July 2026

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Comparative study on mouse models of acute exacerbation of pulmonary fibrosis

Xu Ye, Mingrui Zhang, Mengying Liu, Huihui Zhu, Xiaoling Ye, Cheng Jiang, Qi Li, Xinmei Huang, Mengshu Cao
Article Number: 253
Published online on: 24 July 2026

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Correction Open Access

[Corrigendum] TBL1XR1 as a potential therapeutic target that promotes epithelial‑mesenchymal transition in lung squamous cell carcinoma

Yuehua Zhao, Hao Lin, Jingwei Jiang, Mengxi Ge, Xiaohua Liang
Article Number: 252
Published online on: 23 July 2026

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November-2026 Volume 32 Issue 5

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Tislelizumab‑induced psoriasis in a patient with hepatocellular carcinoma: A case report

Zhaochen Sun, Yuqi Zhou, Yeliang Mei, Yitian Chen
Article Number: 319
Published online on: 23 September 2026

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Functional heterogeneity of exosomes in hepatocellular carcinoma (Review)

Shiyan He, Xia Wu, Zhihao Wang, Xiong Zeng, Jing Lin, Jie Wang
Article Number: 318
Published online on: 23 September 2026

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Transforming growth factor β‑activated kinase 1 as a central integrator of immune‑microbiota crosstalk in colitis (Review)

Haoyu Dong, Sirui Wang, Ridong Lai, Guofeng Li
Article Number: 317
Published online on: 23 September 2026

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Integrated bioinformatics and clinical validation of oxidative stress‑associated genes in atrial fibrillation and chronic kidney disease

Jiyi Liu, Zezhou Xie, Huimin Yu, Fengzhi Sun, Ruifeng Wang, Yunbo Ba, Hao Huang, Xiaomeng Yin, Yu Wang
Article Number: 316
Published online on: 23 September 2026

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Pulmonary tuberculosis occurring during the diagnosis and treatment of sarcoidosis complicated by chylothorax: A case report 

Huai-Jie Wang, Xue Li, Wen-Ge Han, Yuan-Yuan Tang, Yan-Yan Zhang, Yu-Bing Wang, Yong Zhang, Xiao-Qi Zhang, Mei-Hua Qu
Article Number: 315
Published online on: 23 September 2026

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[Retracted] Knockdown of lncRNA CCEPR suppresses colorectal cancer progression

Yuxia Duan, Zhixue Fang, Zeya Shi, Ling Zhang
Article Number: 314
Published online on: 22 September 2026

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Prognostic significance of the blood urea nitrogen‑to‑serum albumin ratio in patients with septic shock

Jianhua Liu, Zhengxiang Wei, Sheng Ye, Min Shao
Article Number: 313
Published online on: 21 September 2026

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Endometrial thickness and cancer risk in asymptomatic postmenopausal women: Defining evidence‑based cut‑offs by systematic review and diagnostic meta‑analysis

Yan Song, Hongying Wu, Ting Qin, Nana Li, Meng Wang
Article Number: 312
Published online on: 21 September 2026

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Neurosyphilis presenting as status epilepticus and hemiplegia diagnosed by metagenomic next-generation sequencing: A case report

Hongshan Chu, Shibo Dong, Yuan Zhang, Ruisheng Duan, Ling Li
Article Number: 311
Published online on: 21 September 2026

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BBS10‑related Bardet‑Biedl syndrome with an atypical presentation of diabetes mellitus: A case report

Lei Zhang, Guoliang Li, Hong Chang, Yanhui Dong, Nana Sun, Rina Wu, Likun Han
Article Number: 310
Published online on: 16 September 2026

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Development of a recombinase‑aided amplification assay for rapid and sensitive detection of Pneumocystis jirovecii infection: A single‑center molecular study

Hanhan Zhu, Ben Yang, Ke Chen, Fang Xu, Meihua Qu, Yuanyuan Tang
Article Number: 309
Published online on: 16 September 2026

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Severe steroid‑refractory immune checkpoint inhibitor‑associated pneumonitis and exploration of potential biomarkers: A case report

Yan-Jun Xue, Ai-Zhen Xu, Xin-Da Yin, Lei Wei
Article Number: 308
Published online on: 16 September 2026

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Article

Effects of ketamine and dexmedetomidine on ischemia‑ reperfusion injury in an experimental renal ischemia model

Muhammet Hanifi Erdoğan, Hakan Kardaş, Tülay Zenginkinet, Tuğba Bingöl Tanriverdi, Melek Güra Çelik
Article Number: 307
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox‑LDL‑induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway 

Tian-Jiao Lyu, Zi-Xiu Zhang, Jun Chen, Zong-Jun Liu
Article Number: 306
Published online on: 16 September 2026

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Carrageenan‑induced immunothrombotic models in rodents (Review)

Xiaomu Ma, Daihan Wu, Simin Lv
Article Number: 305
Published online on: 16 September 2026

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Retraction Open Access

[Retracted] Role of peptidylarginine deiminase type 4 in gastric cancer 

Jiang Xin, Xiuqi Song
Article Number: 304
Published online on: 15 September 2026

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Article Open Access

Immune checkpoint inhibitor‑induced myocarditis with myositis and/or myasthenia gravis overlap syndrome: A case series

Qing Sun, Qing Liu, Jiabin Zheng, Yanni Lou, Huijuan Cui, Junyu Ma, Yu Wang, Dantao Peng, Weihe Zhang, Renbin Wang
Article Number: 303
Published online on: 14 September 2026

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Cardiovascular health metrics and the risk of metabolic dysfunction‑associated steatosis liver disease: A meta‑analysis

Gang Fan, Hong Zuo, Bo Liu
Article Number: 302
Published online on: 14 September 2026

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Multiple relapses of cryptogenic organizing pneumonia: A case report

Sheng Xu, Beibei Li, Yanmin Li, Jian Sun, Qiang Wang
Article Number: 301
Published online on: 11 September 2026

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A diagnostic and classification model integrating cTnI, CK‑MB, MYO and NT‑proBNP for cardiovascular diseases

Huaxin Zhang, Jianan Wang, Qi Li, Tong Zhi, Xiandong Chang
Article Number: 300
Published online on: 11 September 2026

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A rare suprasellar lesion with multifocal central nervous system involvement in clinically diagnosed von Hippel‑Lindau disease: A case report

Zekai Wu, Lei Zhang, Meng Tan, Laian Zhang
Article Number: 299
Published online on: 11 September 2026

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Reversible osimertinib‑associated heart failure mimicking cancer recurrence in EGFR‑mutated non‑small cell lung cancer after pneumonectomy: A case report

Hirona Yokoyama, Nobuhito Hara, Rika Sasaki, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Takeshi Kawaguchi, Masatsugu Hamaji, Yuji Nitta, Maiko Takeda, Masayuki Takeda
Article Number: 298
Published online on: 11 September 2026

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Regenerative endodontic treatment for premolars with apical root segment separation and extensive periapical lesions secondary to severe inflammatory root resorption: A report of two cases

Qian Wu, Daniel J. Yen
Article Number: 297
Published online on: 11 September 2026

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Retraction Open Access

[Retracted] Hsp70 inducer, 17‑allylamino‑demethoxygeldanamycin, provides neuroprotection via anti‑inflammatory effects in a rat model of traumatic brain injury

Youquan Gu, Jun Chen, Tianhong Wang, Chaoning Zhou, Zhaodong Liu, Lanhua Ma
Article Number: 296
Published online on: 10 September 2026

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Case Report

Relapsed/refractory multiple myeloma with extramedullary plasmacytomas successfully rechallenged with humanized B‑cell maturation antigen‑directed chimeric antigen receptor T‑cell immunotherapy in an advanced disease stage: A case report

Runfeng Zhang, Lili Cheng, Jinghua Liu, Lu Zhang, Junling Zhuang
Article Number: 295
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] JWA regulates human esophageal squamous cell carcinoma and human esophageal cells through different mitogen‑activated protein kinase signaling pathways

Jie Lin, Tieliang Ma, Xiaodong Jiang, Zhijun Ge, Weiliang Ding, Yuanyuan Wu, Guojun Jiang, Jiake Feng, Guoxing Cui, Yongfei Tan
Article Number: 294
Published online on: 07 September 2026

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