Palliation double stenting for malignant biliary and duodenal obstruction

Zhao,Liang; Xu,Haitao; Zhang,Yubao

doi:10.3892/etm.2015.2875

January-2016 Volume 11 Issue 1

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January-2016 Volume 11 Issue 1

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Article

Palliation double stenting for malignant biliary and duodenal obstruction

Authors:
- Liang Zhao
- Haitao Xu
- Yubao Zhang
View Affiliations / Copyright

Affiliations: Department of Hepatopancreatobiliary Surgery, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang 150040, P.R. China
Pages: 348-352
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Published online on: November 18, 2015

https://doi.org/10.3892/etm.2015.2875
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Abstract

The surgical management of patients with malignant biliary and duodenal obstruction is complex. Tumor excision is no longer possible in the majority of patients with malignant obstructive jaundice and duodenal obstruction. The aim of the present study was to evaluate the effectiveness of intraluminal dual stent placement in malignant biliary and duodenal obstruction. In total, 20 patients with malignant obstructive jaundice and duodenal obstruction, including 6 with pancreatic carcinoma, 11 with cholangiocarcinoma, 1 with duodenal carcinoma and 2 with abdominal lymph node metastasis, were treated with intraluminal stent placement. Bile duct obstruction with late occurrence of duodenal obstruction was observed in 16 cases, and duodenal obstruction followed by a late occurrence of bile duct obstruction was observed in 3 cases, while, in 1 case, bile duct obstruction and duodenal obstruction occurred simultaneously. After X‑ray fluoroscopy revealed obstruction in the bile duct and duodenum, stents were placed into the respective lumens. Percutaneous transhepatic placement was employed for the biliary stent, while the duodenal stent was placed perioraly. The clinical outcomes, including complications associated with the procedures and patency of the stents, were evaluated. The biliary and duodenal stents were successfully implanted in 18 patients and the technical success rate was 90% (18/20). A total of 39 stents were implanted in 20 patients. In 2 cases, duodenal stent placement failed following biliary stent placement. Duodenal obstruction remitted in 15 patients, and 1 patient succumbed to aspiration pneumonia 5 days after the procedure. No severe complications were observed in any other patient. The survival time of the 18 patients was 5‑21 months (median, 9.6 months), and 6 of those patients survived for >12 months. The present study suggests that X‑ray fluoroscopy‑guided intraluminal stent implantation is an effective procedure for the treatment of malignant biliary and duodenal obstruction.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Palliation double stenting for malignant biliary and duodenal obstruction

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