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Article

Time course of various cell origin circulating microparticles in ST-segment elevation myocardial infarction patients undergoing percutaneous transluminal coronary intervention

  • Authors:
    • Boda Zhou
    • Jizhao Li
    • Shaomin Chen
    • Enchen Zhou
    • Lemin Zheng
    • Lingyun Zu
    • Wei Gao
  • View Affiliations / Copyright

    Affiliations: Department of Cardiovascular Medicine, Peking University Third Hospital, Beijing 100191, P.R. China, Institute of Cardiovascular Sciences and Institute of Systems Biomedicine, School of Basic Medical Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health, Peking University Health Science Center, Beijing 100191, P.R. China
  • Pages: 1481-1486
    |
    Published online on: February 9, 2016
       https://doi.org/10.3892/etm.2016.3060
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Abstract

The present study aimed to investigate the time course of changes in microparticles (MPs) in patients with ST-segment elevation myocardial infarction (STEMI) that underwent percutaneous transluminal coronary intervention (PCI). A total of 24 STEMI patients undergoing primary PCI were enrolled, and circulating MPs were detected immediately prior to and after PCI, and at 4, 24 and 48 h post-PCI. Standard Megamix beads, based measurement protocols, were employed to measure MPs of different cell origin, including endothelial MPs (EMPs), platelet MPs (PMPs) and leukocyte‑derived MPs (LMPs), which were identified by CD144, CD41 and CD45, respectively. The results indicated that PMP levels were evidently elevated immediately after PCI, and reached a maximum level at 48 h. In addition, LMP and EMP levels were significantly decreased immediately after the PCI, and then increased gradually with time. The total quantity of the three aforementioned MP types increased gradually at 48 h following PCI. Furthermore, coronary angiographic Gensini scores were significantly positively correlated with the level of PMPs (r2=0.42; P=0.0006). Log‑normalized high sensitivity‑C‑reactive‑protein was also significantly correlated with LMPs (r2=0.86; P<0.01). In conclusion, the time course of the changes in circulating MPs of different cell origin, provided information on possible functions of different MPs in STEMI.
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1 

György B, Szabó TG, Pásztói M, Pál Z, Misják P, Aradi B, László V, Pállinger E, Pap E, Kittel A, et al: Membrane vesicles, current state-of-the-art: Emerging role of extracellular vesicles. Cell Mol Life Sci. 68:2667–2688. 2011. View Article : Google Scholar : PubMed/NCBI

2 

Nozaki T, Sugiyama S, Koga H, Sugamura K, Ohba K, Matsuzawa Y, Sumida H, Matsui K, Jinnouchi H and Ogawa H: Significance of a multiple biomarkers strategy including endothelial dysfunction to improve risk stratification for cardiovascular events in patients at high risk for coronary heart disease. J Am Coll Cardiol. 54:601–608. 2009. View Article : Google Scholar : PubMed/NCBI

3 

Hansson GK: Inflammation, atherosclerosis and coronary artery disease. N Engl J Med. 352:1685–1695. 2005. View Article : Google Scholar : PubMed/NCBI

4 

Liuzzo G, Biasucci LM, Gallimore JR, Grillo RL, Rebuzzi AG, Pepys MB and Maseri A: The prognostic value of C-reactive protein and serum amyloid a protein in severe unstable angina. N Engl J Med. 331:417–424. 1994. View Article : Google Scholar : PubMed/NCBI

5 

Lindahl B, Toss H, Siegbahn A, Venge P and Wallentin L: Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. FRISC Study Group. Fragmin during Instability in Coronary Artery Disease. N Engl J Med. 343:1139–1147. 2000. View Article : Google Scholar : PubMed/NCBI

6 

Habersberger J, Strang F, Scheichl A, Htun N, Bassler N, Merivirta RM, Diehl P, Krippner G, Meikle P, Eisenhardt SU, et al: Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction. Cardiovasc Res. 96:64–72. 2012. View Article : Google Scholar : PubMed/NCBI

7 

Inoue T, Komoda H, Kotooka N, Morooka T, Fujimatsu D, Hikichi Y, Soma R, Uchida T and Node K: Increased circulating platelet-derived microparticles are associated with stent-induced vascular inflammation. Atherosclerosis. 196:469–476. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Biasucci LM, Porto I, Di Vito L, De Maria GL, Leone AM, Tinelli G, Tritarelli A, Di Rocco G, Snider F, Capogrossi MC and Crea F: Differences in microparticle release in patients with acute coronary syndrome and stable angina. Circ J. 76:2174–2182. 2012. View Article : Google Scholar : PubMed/NCBI

9 

Leroyer AS, Rautou PE, Silvestre JS, Castier Y, Lesèche G, Devue C, Duriez M, Brandes RP, Lutgens E, Tedgui A and Boulanger CM: CD40 ligand+ microparticles from human atherosclerotic plaques stimulate endothelial proliferation and angiogenesis a potential mechanism for intraplaque neovascularization. J Am Coll Cardiol. 52:1302–1311. 2008. View Article : Google Scholar : PubMed/NCBI

10 

Stępień E, Stankiewicz E, Zalewski J, Godlewski J, Zmudka K and Wybrańska I: Number of microparticles generated during acute myocardial infarction and stable angina correlates with platelet activation. Arch Med Res. 43:31–35. 2012. View Article : Google Scholar : PubMed/NCBI

11 

Pollack CV Jr, Diercks DB, Roe MT and Peterson ED: American College of Cardiology; American Heart Association: 2004 American college of cardiology/American Heart Association guidelines for the management of patients with ST-elevation myocardial infarction: Implications for emergency department practice. Ann Emerg Med. 45:363–376. 2005. View Article : Google Scholar : PubMed/NCBI

12 

Stringer KA: TIMI grade flow, mortality, and the GUSTO-III trial. Pharmacotherapy. 18:699–705. 1998.PubMed/NCBI

13 

Gensini GG: A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol. 51:6061983. View Article : Google Scholar : PubMed/NCBI

14 

Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, et al: 2011 ACCF/AHA/SCAI Guideline for percutaneous coronary intervention. A report of the American college of cardiology foundation/American heart association task force on practice guidelines and the society for cardiovascular angiography and interventions. J Am Coll Cardiol. 58:e44–e122. 2011. View Article : Google Scholar : PubMed/NCBI

15 

Chen S, Guo L, Cui M, Sun L and Mi L: Dynamic changes in serum angiopoietin-1, angiopoietin-2 and angiopoietin-2/angiopoietin-1 ratio in acute myocardial infarction patients treated with primary percutaneous coronary intervention. Biomarkers. 17:441–446. 2012. View Article : Google Scholar : PubMed/NCBI

16 

Robert S, Poncelet P, Lacroix R, Arnaud L, Giraudo L, Hauchard A, Sampol J and Dignat-George F: Standardization of platelet-derived microparticle counting using calibrated beads and a Cytomics FC500 routine flow cytometer: A first step towards multicenter studies? J Thromb Haemost. 7:190–197. 2009. View Article : Google Scholar : PubMed/NCBI

17 

Empana JP, Boulanger CM, Tafflet M, Renard JM, Leroyer AS, Varenne O, Prugger C, Silvain J, Tedgui A, Cariou A, et al: Microparticles and sudden cardiac death due to coronary occlusion. The TIDE (Thrombus and Inflammation in sudden DEath) study. Eur Heart J Acute Cardiovasc Care. 4:28–36. 2015. View Article : Google Scholar : PubMed/NCBI

18 

Wang K, Zuo G, Zheng L, Zhang C, Wang D, Cao Z, Hu S and Du X: Effects of tirofiban on platelet activation and endothelial function in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Cell Biochem Biophys. 71:135–142. 2015. View Article : Google Scholar : PubMed/NCBI

19 

Lacroix R, Robert S, Poncelet P, Kasthuri RS, Key NS and Dignat-George F: ISTH SSC Workshop: Standardization of platelet-derived microparticle enumeration by flow cytometry with calibrated beads: Results of the international society on thrombosis and haemostasis SSC collaborative workshop. J Thromb Haemost. 8:2571–2574. 2010. View Article : Google Scholar : PubMed/NCBI

20 

Robert S, Lacroix R, Poncelet P, Harhouri K, Bouriche T, Judicone C, Wischhusen J, Arnaud L and Dignat-George F: High-sensitivity flow cytometry provides access to standardized measurement of small-size microparticles-brief report. Arterioscler Thromb Vasc Biol. 32:1054–1058. 2012. View Article : Google Scholar : PubMed/NCBI

21 

Biasucci LM, Porto I, Di Vito L, De Maria GL, Leone AM, Tinelli G, Tritarelli A, Di Rocco G, Snider F, Capogrossi MC and Crea F: Differences in microparticle release in patients with acute coronary syndrome and stable angina. Circ J. 76:2174–2182. 2012. View Article : Google Scholar : PubMed/NCBI

22 

Sinauridze EI, Kireev DA, Popenko NY, Pichugin AV, Panteleev MA, Krymskaya OV and Ataullakhanov FI: Platelet microparticle membranes have 50- to 100-fold higher specific procoagulant activity than activated platelets. Thromb Haemost. 97:425–434. 2007.PubMed/NCBI

23 

Angelillo-Scherrer A: Leukocyte-derived microparticles in vascular homeostasis. Circ Res. 110:356–369. 2012. View Article : Google Scholar : PubMed/NCBI

24 

Vidal C, Spaulding C, Picard F, Schaison F, Melle J, Weber S and Fontenay-Roupie M: Flow cytometry detection of platelet procoagulation activity and microparticles in patients with unstable angina treated by percutaneous coronary angioplasty and stent implantation. Thromb Haemost. 86:784–790. 2001.PubMed/NCBI

25 

Lacroix R and Dignat-George F: Microparticles as a circulating source of procoagulant and fibrinolytic activities in the circulation. Thromb Res. 129(Suppl 2): S27–S29. 2012. View Article : Google Scholar : PubMed/NCBI

26 

Lacroix R, Plawinski L, Robert S, Doeuvre L, Sabatier F, de Lizarrondo Martinez S, Mezzapesa A, Anfosso F, Leroyer AS, Poullin P, et al: Leukocyte- and endothelial-derived microparticles: A circulating source for fibrinolysis. Haematologica. 97:1864–1872. 2012. View Article : Google Scholar : PubMed/NCBI

27 

Tan KT, Tayebjee MH, Lim HS and Lip GY: Clinically apparent atherosclerotic disease in diabetes is associated with an increase in platelet microparticle levels. Diabet Med. 22:1657–1662. 2005. View Article : Google Scholar : PubMed/NCBI

28 

Hron G, Kollars M, Weber H, Sagaster V, Quehenberger P, Eichinger S, Kyrle PA and Weltermann A: Tissue factor-positive microparticles: Cellular origin and association with coagulation activation in patients with colorectal cancer. Thromb Haemost. 97:119–123. 2007.PubMed/NCBI

29 

Pereira J, Alfaro G, Goycoolea M, Quiroga T, Ocqueteau M, Massardo L, Pérez C, Sáez C, Panes O, Matus V and Mezzano D: Circulating platelet-derived microparticles in systemic lupus erythematosus. Association with increased thrombin generation and procoagulant state. Thromb Haemost. 95:94–99. 2006.PubMed/NCBI

30 

Chen J, Zhang Y, Liu J, Chen MH, Guo YL, Zhu CG, Xu RX, Dong Q and Li JJ: Role of lipoprotein(a) in predicting the severity of new on-set coronary artery disease in type 2 diabetics: A Gensini score evaluation. Diab Vasc Dis Res. 12:258–264. 2015. View Article : Google Scholar : PubMed/NCBI

31 

Mori T, Sasaki J, Kawaguchi H, Handa K, Takada Y, Matsunaga A, Kono S and Arakawa K: Serum glycoproteins and severity of coronary atherosclerosis. Am Heart J. 129:234–238. 1995. View Article : Google Scholar : PubMed/NCBI

32 

Handa K, Kono S, Saku K, Sasaki J, Kawano T, Sasaki Y, Hiroki T and Arakawa K: Plasma fibrinogen levels as an independent indicator of severity of coronary atherosclerosis. Atherosclerosis. 77:209–213. 1989. View Article : Google Scholar : PubMed/NCBI

33 

Woloshin S and Schwartz LM: Distribution of C-reactive protein values in the United States. N Engl J Med. 352:1611–1613. 2005. View Article : Google Scholar : PubMed/NCBI

34 

Rohde LE, Hennekens CH and Ridker PM: Survey of C-reactive protein and cardiovascular risk factors in apparently healthy men. Am J Cardiol. 84:1018–1022. 1999. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhou B, Li J, Chen S, Zhou E, Zheng L, Zu L and Gao W: Time course of various cell origin circulating microparticles in ST-segment elevation myocardial infarction patients undergoing percutaneous transluminal coronary intervention. Exp Ther Med 11: 1481-1486, 2016.
APA
Zhou, B., Li, J., Chen, S., Zhou, E., Zheng, L., Zu, L., & Gao, W. (2016). Time course of various cell origin circulating microparticles in ST-segment elevation myocardial infarction patients undergoing percutaneous transluminal coronary intervention. Experimental and Therapeutic Medicine, 11, 1481-1486. https://doi.org/10.3892/etm.2016.3060
MLA
Zhou, B., Li, J., Chen, S., Zhou, E., Zheng, L., Zu, L., Gao, W."Time course of various cell origin circulating microparticles in ST-segment elevation myocardial infarction patients undergoing percutaneous transluminal coronary intervention". Experimental and Therapeutic Medicine 11.4 (2016): 1481-1486.
Chicago
Zhou, B., Li, J., Chen, S., Zhou, E., Zheng, L., Zu, L., Gao, W."Time course of various cell origin circulating microparticles in ST-segment elevation myocardial infarction patients undergoing percutaneous transluminal coronary intervention". Experimental and Therapeutic Medicine 11, no. 4 (2016): 1481-1486. https://doi.org/10.3892/etm.2016.3060
Copy and paste a formatted citation
x
Spandidos Publications style
Zhou B, Li J, Chen S, Zhou E, Zheng L, Zu L and Gao W: Time course of various cell origin circulating microparticles in ST-segment elevation myocardial infarction patients undergoing percutaneous transluminal coronary intervention. Exp Ther Med 11: 1481-1486, 2016.
APA
Zhou, B., Li, J., Chen, S., Zhou, E., Zheng, L., Zu, L., & Gao, W. (2016). Time course of various cell origin circulating microparticles in ST-segment elevation myocardial infarction patients undergoing percutaneous transluminal coronary intervention. Experimental and Therapeutic Medicine, 11, 1481-1486. https://doi.org/10.3892/etm.2016.3060
MLA
Zhou, B., Li, J., Chen, S., Zhou, E., Zheng, L., Zu, L., Gao, W."Time course of various cell origin circulating microparticles in ST-segment elevation myocardial infarction patients undergoing percutaneous transluminal coronary intervention". Experimental and Therapeutic Medicine 11.4 (2016): 1481-1486.
Chicago
Zhou, B., Li, J., Chen, S., Zhou, E., Zheng, L., Zu, L., Gao, W."Time course of various cell origin circulating microparticles in ST-segment elevation myocardial infarction patients undergoing percutaneous transluminal coronary intervention". Experimental and Therapeutic Medicine 11, no. 4 (2016): 1481-1486. https://doi.org/10.3892/etm.2016.3060
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