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Article

Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis

  • Authors:
    • Tian-Ying Feng
    • Xue-Feng Han
    • Rui Lang
    • Fei Wang
    • Qiong Wu
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasound, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia Autonomous Region 010017, P.R. China, Department of Emergency, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia Autonomous Region 010017, P.R. China, Department of Neurosurgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region 010050, P.R. China, Department of Magnetic Resonance Imaging, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region 010050, P.R. China
  • Pages: 1930-1936
    |
    Published online on: March 15, 2016
       https://doi.org/10.3892/etm.2016.3166
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Abstract

The aim of this meta-analysis was to investigate the accuracy of subtraction computed tomography angiography (CTA) for diagnosing intracranial aneurysms. A systematic literature search up to January 1, 2013 was performed in PubMed. Two independent reviewers selected 8 studies that compared subtraction CTA with digital subtraction angiography. Data from the studies were used to construct a 2x2 contingency table on a per‑patient basis in ≥5 diseased and 5 non‑diseased patients, with additional data on a per‑aneurysm basis. Overall, subtraction CTA had a pooled sensitivity of 99% [95% confidence interval (CI), 95‑100%] and specificity of 94% (95% CI, 86‑97%) for detecting and ruling out cerebral aneurysms, respectively, on a per‑patient basis. On a per‑aneurysm basis, the pooled sensitivity was 96% (95% CI, 90‑99%), and the specificity was 91% (95% CI, 85‑95%). In conclusion, subtraction CTA is a highly sensitive, specific and non‑inva­sive method for the diagnosis and evaluation of intracranial aneurysms.
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Copy and paste a formatted citation
Spandidos Publications style
Feng T, Han X, Lang R, Wang F and Wu Q: Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis. Exp Ther Med 11: 1930-1936, 2016.
APA
Feng, T., Han, X., Lang, R., Wang, F., & Wu, Q. (2016). Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis. Experimental and Therapeutic Medicine, 11, 1930-1936. https://doi.org/10.3892/etm.2016.3166
MLA
Feng, T., Han, X., Lang, R., Wang, F., Wu, Q."Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis". Experimental and Therapeutic Medicine 11.5 (2016): 1930-1936.
Chicago
Feng, T., Han, X., Lang, R., Wang, F., Wu, Q."Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis". Experimental and Therapeutic Medicine 11, no. 5 (2016): 1930-1936. https://doi.org/10.3892/etm.2016.3166
Copy and paste a formatted citation
x
Spandidos Publications style
Feng T, Han X, Lang R, Wang F and Wu Q: Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis. Exp Ther Med 11: 1930-1936, 2016.
APA
Feng, T., Han, X., Lang, R., Wang, F., & Wu, Q. (2016). Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis. Experimental and Therapeutic Medicine, 11, 1930-1936. https://doi.org/10.3892/etm.2016.3166
MLA
Feng, T., Han, X., Lang, R., Wang, F., Wu, Q."Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis". Experimental and Therapeutic Medicine 11.5 (2016): 1930-1936.
Chicago
Feng, T., Han, X., Lang, R., Wang, F., Wu, Q."Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis". Experimental and Therapeutic Medicine 11, no. 5 (2016): 1930-1936. https://doi.org/10.3892/etm.2016.3166
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