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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May-2016 Volume 11 Issue 5

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Impact Factor: 2.3

Review Open Access

The role of heart rate variability in sports physiology (Review)

Jin‑Guo Dong
Pages: 1531-1536
Published online on: 23 February 2016

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Review Open Access

Non-invasive treatment options for focal cortical dysplasia (Review)

Ting‑Ting Wang, Dong Zhou
Pages: 1537-1541
Published online on: 22 February 2016

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Review Open Access

Advances in neonatal screening for primary immune deficiencies (Review)

Tingting Jiang, Zhenguang Li, Qiuli Zhang
Pages: 1542-1544
Published online on: 01 March 2016

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Review Open Access

Protein intake and obesity in young adolescents (Review)

Shumei Xu, Ying Xue
Pages: 1545-1549
Published online on: 09 March 2016

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Review Open Access

Current diagnosis and treatments for critical congenital heart defects (Review)

Zhandong Zeng, Hongwei Zhang, Fengli Liu, Ning Zhang
Pages: 1550-1554
Published online on: 15 March 2016

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Article Open Access

Diagnostic value of contrast‑enhanced ultrasound in papillary thyroid microcarcinoma

Hong Yan Chen, Wei Yan Liu, Hui Zhu, Dao Wen Jiang, Dong Hua Wang, Yongqi Chen, Weihua Li, Gaofeng Pan
Pages: 1555-1562
Published online on: 19 February 2016

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Article Open Access

Inhibition of the NMDA receptor protects the rat sciatic nerve against ischemia/reperfusion injury

Tie Ke, Renbin Li, Wenchang Chen
Pages: 1563-1572
Published online on: 11 March 2016

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Article Open Access

Protective effect of adipose-derived mesenchymal stem cells against acute kidney injury induced by ischemia-reperfusion in Sprague-Dawley rats

Hussein Sheashaa, Ahmed Lotfy, Fatma Elhusseini, Azza Abdel Aziz, Azza Baiomy, Samah Awad, Aziza Alsayed, Abdel‑Hady El‑Gilany, Mohamed‑Ahdy A.A. Saad, Khaled Mahmoud, Faten Zahran, Dalia A. Salem, Ahmed Sarhan, Hassan Abdel Ghaffar, Mohamed Sobh
Pages: 1573-1580
Published online on: 26 February 2016

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Article Open Access

Association of endothelial progenitor cells and peptic ulcer treatment in patients with type 2 diabetes mellitus

Zhihong Nie, Limin Xu, Chuanyuan Li, Tao Tian, Pingping Xie, Xia Chen, Bojing Li
Pages: 1581-1586
Published online on: 26 February 2016

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Article Open Access

Human lymphatic endothelial cells contribute to epithelial ovarian carcinoma metastasis by promoting lymphangiogenesis and tumour cell invasion

Yihong Xie, Yanping Zhong, Ting Gao, Xinying Zhang, Li Li, Heyun Ruan, Danrong Li
Pages: 1587-1594
Published online on: 09 March 2016

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Article Open Access

Transplantation of mesenchymal stem cells promotes the functional recovery of the central nervous system following cerebral ischemia by inhibiting myelin‑associated inhibitor expression and neural apoptosis

Nianping Feng, Guang Hao, Fenggang Yang, Fujun Qu, Haihong Zheng, Songlan Liang, Yonghua Jin
Pages: 1595-1600
Published online on: 19 February 2016

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Article Open Access

Evaluation of 29 indicators for the prognosis of advanced non‑small cell lung cancer with cytokine‑induced killer cell therapy combined with chemotherapy

Hejin Jia, Yaping Tian, Chao Guang Jiang, Weidong Han
Pages: 1601-1610
Published online on: 22 February 2016

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Article Open Access

Astragalus membranaceus ameliorates renal interstitial fibrosis by inhibiting tubular epithelial-mesenchymal transition in vivo and in vitro

Guang Shan, Xiang‑Jun Zhou, Yue Xia, Hui‑Jun Qian
Pages: 1611-1616
Published online on: 11 March 2016

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Article

Effect of lysophosphatidic acid on the immune inflammatory response and the connexin 43 protein in myocardial infarction

Duoduo Zhang, Yan Zhang, Chunyan Zhao, Wenjie Zhang, Guoguang Shao, Hong Zhang
Pages: 1617-1624
Published online on: 09 March 2016

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Article

Protective role of adenovirus vector-mediated interleukin-10 gene therapy on endogenous islet β-cells in recent-onset type 1 diabetes in NOD mice

Cheng Li, Lijuan Zhang, Yanyan Chen, Xiaojie Lin, Tang Li
Pages: 1625-1632
Published online on: 15 March 2016

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Article Open Access

Association between glutathione S-transferase M1/T1 gene polymorphisms and susceptibility to endometriosis: A systematic review and meta-analysis

Xiaoyan Xin, Zhishan Jin, Huajian Gu, Yuanyue Li, Tingting Wu, Teng Hua, Hongbo Wang
Pages: 1633-1646
Published online on: 26 February 2016

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Article Open Access

An examination of the effects of different doses of recombinant human growth hormone on children with growth hormone deficiency

Ying Xue, Yiqing Gao, Shuqin Wang, Pei Wang
Pages: 1647-1652
Published online on: 19 February 2016

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Article Open Access

Gas chromatography-mass spectrometric method-based urine metabolomic profile of rats with pelvic inflammatory disease

Wei Zou, Xiaoke Wen, Xiaoqi Sheng, Yi Zheng, Zuoqi Xiao, Jieying Luo, Shuqiong Chen, Yichao Wang, Zeneng Cheng, Daxiong Xiang, Yichu Nie
Pages: 1653-1660
Published online on: 10 March 2016

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Article Open Access

Notch signaling is active in normal mouse middle ear epithelial cells

Xiang Liu, Hai‑Bin Sheng, Rui Ma, Juan‑Mei Yang, Wen‑Wei Luo, Xiao‑Yu Yang, Dong‑Dong Ren, Fang‑Lu Chi
Pages: 1661-1667
Published online on: 11 March 2016

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Article Open Access

Expression and function of hematopoiesis-stimulating factor receptors on the GPI‑ and GPI+ hematopoietic stem cells of patients with paroxysmal nocturnal hemoglobinuria/aplastic anemia syndrome

Rong Fu, Shao‑Xue Ding, Yi Liu, Li‑Juan Li, Hui Liu, Hong‑Lei Wang, Tian Zhang, Zong‑Hong Shao
Pages: 1668-1672
Published online on: 15 March 2016

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Article Open Access

Fibroscan improves the diagnosis sensitivity of liver fibrosis in patients with chronic hepatitis B

Rengang Huang, Nan Jiang, Renguo Yang, Xiaoxia Geng, Jianmei Lin, Gang Xu, Dandan Liu, Jidog Chen, Guo Zhou, Shuqiang Wang, Tingting Luo, Jiazhen Wu, Xiaoshu Liu, Kaiju Xu, Xingxiang Yang
Pages: 1673-1677
Published online on: 09 March 2016

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Article Open Access

Effect of bisphosphonates on the mandibular bone and gingival epithelium of rats without tooth extraction

Francesco Saverio De Ponte, Luciano Catalfamo, Gregorio Micali, Michele Runci, Giuseppina Cutroneo, Giovanna Vermiglio, Antonio Centofanti, Giuseppina Rizzo
Pages: 1678-1684
Published online on: 15 March 2016

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Article Open Access

Selected gene profiles of stressed NSC‑34 cells and rat spinal cord following peripheral nerve reconstruction and minocycline treatment

Gerburg Keilhoff, Benjamin Lucas, Katja Uhde, Hisham Fansa
Pages: 1685-1699
Published online on: 02 March 2016

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Article Open Access

Metformin induces apoptosis via a mitochondria-mediated pathway in human breast cancer cells in vitro

Zhen‑Yuan Gao, Zhe Liu, Ming‑Hong Bi, Jing‑Jing Zhang, Zheng‑Quan Han, Xiao Han, Hong‑Ya Wang, Guo‑Ping Sun, Hao Liu
Pages: 1700-1706
Published online on: 10 March 2016

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Article Open Access

Co‑expression network‑based analysis of hippocampal expression data associated with Alzheimer's disease using a novel algorithm

Hong Yue, Bo Yang, Fang Yang, Xiao‑Li Hu, Fan‑Bin Kong
Pages: 1707-1715
Published online on: 03 March 2016

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Article Open Access

Diagnostic accuracy of deep vein thrombosis is increased by analysis using combined optimal cut‑off values of postoperative plasma D‑dimer levels

Yong Jiang, Jie Li, Yang Liu, Weiguo Zhang
Pages: 1716-1720
Published online on: 02 March 2016

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Article Open Access

Efficacy, safety and administration timing of trastuzumab in human epidermal growth factor receptor 2 positive breast cancer patients: A meta‑analysis

Yuan‑Yuan Chen, Lin‑Wei Wang, Fang‑Fang Chen, Bi‑Bo Wu, Bin Xiong
Pages: 1721-1733
Published online on: 19 February 2016

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Article Open Access

Establishment of a prediction model of changing trends in cardiac hypertrophy disease based on microarray data screening

Caiyan Ma, Yongjun Ying, Tianjie Zhang, Wei Zhang, Hui Peng, Xufeng Cheng, Lin Xu, Hong Tong
Pages: 1734-1740
Published online on: 24 February 2016

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Case Report Open Access

Effect of immune suppression on metastasis in a patient with hepatocellular carcinoma metastasized to the colon and stomach: A case report

Dongde Wu, Shaozhong Wei, Baozhen Liu, Xinghong Wu, Yaojun Feng, Chenggang Luo, Yiqing Ju, Jianjun Liang
Pages: 1741-1747
Published online on: 26 February 2016

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Article Open Access

Imperatorin derivative OW1 inhibits the upregulation of TGF-β and MMP-2 in renovascular hypertension-induced cardiac remodeling

Nan Zhou, Yaning Zhu, Peng Zhang, Yu Zhang, Mingyao Zhou, Tao Wang, Langchong He
Pages: 1748-1754
Published online on: 15 March 2016

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Article Open Access

NSAIDs modulate GABA-activated currents via Ca2+-activated Cl‑ channels in rat dorsal root ganglion neurons

Lei Zhao, Li Li, Ke‑Tao Ma, Yang Wang, Jing Li, Wen‑Yan Shi, He Zhu, Zhong‑Shuang Zhang, Jun‑Qiang Si
Pages: 1755-1761
Published online on: 15 March 2016

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Article Open Access

Expression, purification and production of antisera against recombinant truncated VP22 protein

Xian Yu, Jun Lei, Qin Yang, Zhengmin Xu, Yan Wang
Pages: 1762-1766
Published online on: 22 February 2016

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Article Open Access

Association between insulin dosage and insulin usage time, and coronary artery lesions in patients with type 2 diabetes and coronary heart disease

Xiao‑Li Luo, Qing‑Kai Yan, Yan Wang, Hui Fang, Hong‑Yong Wang, Yun Bai, Chun‑Yu Zeng, Xu‑Kai Wang
Pages: 1767-1771
Published online on: 29 February 2016

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Article Open Access

Value of UVJ-M in the diagnosis of SUI in late pregnancy and postpartum

Guixin Zhang, Wei Jiang, Quanwei Guo, Quanrong Guo
Pages: 1772-1776
Published online on: 01 March 2016

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Article

Negative signals for adenomyomatosis of the gallbladder upon diffusion‑weighted whole body imaging with background body signal suppression/T2‑weighted image fusion analysis

Minoru Tomizawa, Fuminobu Shinozaki, Kazunori Fugo, Takafumi Sunaoshi, Eriko Sugiyama, Daisuke Kano, Misaki Shite, Ryouta Haga, Yoshiya Fukamizu, Satoshi Kagayama, Rumiko Hasegawa, Yoshinori Shirai, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Takashi Kishimoto, Naoki Ishige
Pages: 1777-1780
Published online on: 02 March 2016

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Article

Analysis of renal function during telaprevir-based triple therapy for chronic hepatitis C

Motoyuki Kohjima, Miho Kurokawa, Munechika Enjoji, Tsuyoshi Yoshimoto, Tsukasa Nakamura, Tomoko Ohashi, Kunitaka Fukuizumi, Naohiko Harada, Yusuke Murata, Kazuhisa Matsunaga, Masaki Kato, Kazuhiro Kotoh, Makoto Nakamuta
Pages: 1781-1787
Published online on: 09 March 2016

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Article

Immunogenicity of varicella zoster virus glycoprotein E DNA vaccine

Lidao Bao, Guomin Wei, Hongmei Gan, Xianhua Ren, Ruilian Ma, Yi Wang, Haijun Lv
Pages: 1788-1794
Published online on: 19 February 2016

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Case Report

Gallbladder agenesis and atrial septal defect: A case report

Yongqiang Liu, Ni Ao, Haiping Zhao
Pages: 1795-1798
Published online on: 29 February 2016

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Case Report

An unusual case of anaplastic lymphoma kinase‑positive large B‑cell lymphoma in an elderly patient: A case report and discussion

Hanzhen Xiong, Shao‑Yan Liu, Yue‑Xin Yang, Xue‑Xian Tan, Qiu‑Ping Luo, Juan Peng, Zhong‑Tang Xiong, Hui Chen, Juan Chen, Zhi Li, Qing‑Ping Jiang
Pages: 1799-1802
Published online on: 02 March 2016

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Article

miR141 expression is downregulated and negatively correlated with STAT5 expression in esophageal squamous cell carcinoma

Hongwu Tan, Yunfeng Zhu, Jiling Zhang, Lijun Peng, Tao Ji
Pages: 1803-1808
Published online on: 19 February 2016

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Case Report

Abdominal distension and diarrhea as the main symptoms of primary amyloidosis: A case report and literature review

Jian Zhang, Chuxiao Shao, Jinde Zhu, Chaoyong Tu, Xinliang Lv
Pages: 1809-1811
Published online on: 19 February 2016

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Article

Sclerostin is essential for alveolar bone loss in occlusal hypofunction

Yang Xu, Lufei Wang, Yao Sun, Xianglong Han, Tian Gao, Xin Xu, Tian Chen, Xuefeng Zhao, Huan Zeng, Yanmin Wang, Ding Bai
Pages: 1812-1818
Published online on: 02 March 2016

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Article

Opioid endocrinopathy: A clinical problem in patients with cancer pain

Alparslan Merdin, Fatma Avci Merdin, Şeyda Gündüz, Hakan Bozcuk, Hasan Şenol Coşkun
Pages: 1819-1822
Published online on: 11 March 2016

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Case Report

Secondary erythromelalgia successfully treated with patient‑controlled epidural analgesia and interferon α‑2b: A case report and review of the literature

Xingzhi Li, Yaomin Li, Yao Qu, Laijin Lu
Pages: 1823-1826
Published online on: 19 February 2016

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Article

Penehyclidine ameliorates acute lung injury by inhibiting Toll-like receptor 2/4 expression and nuclear factor-κB activation

Na Wang, Yue Su, Xiang‑Ming Che, Hui Zheng, Zhi‑Guo Shi
Pages: 1827-1832
Published online on: 11 March 2016

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Article

Efficient inhibition of human immunodeficiency virus replication using novel modified microRNA-30a targeting 3'-untranslated region transcripts

Ahmad Nejati, Shohreh Shahmahmoodi, Ehsan Arefian, Zabihollah Shoja, Sayed‑Mahdi Marashi, Hamideh Tabatabaie, Yaghoub Mollaei‑Kandelous, Masoud Soleimani, Rakhshandeh Nategh
Pages: 1833-1838
Published online on: 02 March 2016

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Article

Effects of Shenqi Fuzheng injection on Fas/FasL protein expression levels in the cardiomyocytes of a mouse model of viral myocarditis

Tianmin Wu, Jinshui Chen, Liufang Fan, Wenyan Xie, Changsheng Xu, Huajun Wang
Pages: 1839-1846
Published online on: 15 March 2016

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Article

Expression of pituitary tumor-transforming 2 in human glioblastoma cell lines and its role in glioblastoma tumorigenesis

Yunbao Guo, Yimeng Shao, Jing Chen, Songbai Xu, Xingdong Zhang, Haiyan Liu
Pages: 1847-1852
Published online on: 15 March 2016

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Article

Genistein induces adipogenic differentiation in human bone marrow mesenchymal stem cells and suppresses their osteogenic potential by upregulating PPARγ

Li‑Yan Zhang, Hao‑Gang Xue, Ji‑Ying Chen, Wei Chai, Ming Ni
Pages: 1853-1858
Published online on: 02 March 2016

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Article

Autophagy mediates oral submucous fibrosis

Jiang Li, Ting‑Ting Zhao, Peng Zhang, Chao‑Jin Xu, Zhuo‑Xiang Rong, Zi‑Yi Yan, Chang‑Yun Fang
Pages: 1859-1864
Published online on: 11 March 2016

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Article

CXCR4 inhibitor attenuates ovalbumin-induced airway inflammation and hyperresponsiveness by inhibiting Th17 and Tc17 cell immune response

Huilong Chen, Xiangqin Xu, Jieming Teng, Sheng Cheng, Hansvin Bunjhoo, Yong Cao, Jin Liu, Jungang Xie, Congyi Wang, Yongjian Xu, Weining Xiong
Pages: 1865-1870
Published online on: 10 March 2016

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Case Report

Collapsing glomerulopathy with rare associated coxsackie virus infection: A case report

Xuejing Zhu, Hong Liu, Shuguang Yuan, Xiangqing Xu, Zhen Dong, Fuyou Liu
Pages: 1871-1874
Published online on: 15 March 2016

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Article

Effects of nitric oxide on the biological behavior of HepG2 human hepatocellular carcinoma cells

Lei Zhou, Heng Zhang, Jie Wu
Pages: 1875-1880
Published online on: 02 March 2016

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Article

Olive oil exhibits osteoprotection in ovariectomized rats without estrogenic effects

Xiaohua Zheng, Huijuan Huang, Xiaobing Zheng, Baoheng Li
Pages: 1881-1888
Published online on: 10 March 2016

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Case Report

Novel therapy for anti-glomerular basement membrane disease with IgA nephropathy: A case report

Dechao Xu, Jianxiang Wu, Jun Wu, Chenggang Xu, Yuqiang Zhang, Changlin Mei, Xiang Gao
Pages: 1889-1892
Published online on: 11 March 2016

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Case Report

Local recurrent vaginal aggressive angiomyxoma misdiagnosed as cellular angiomyofibroblastoma: A case report

Yin‑Feng Wang, Hong‑Lang Qian, Hang‑Mei Jin
Pages: 1893-1895
Published online on: 19 February 2016

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Article

Allicin inhibits transient outward potassium currents in mouse ventricular myocytes

Hong Cao, Congxin Huang, Xin Wang
Pages: 1896-1900
Published online on: 29 February 2016

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Article

CDKN2B, SLC19A3 and DLEC1 promoter methylation alterations in the bone marrow of patients with acute myeloid leukemia during chemotherapy

Qingxiao Hong, Yirun Li, Xiaoying Chen, Huadan Ye, Linlin Tang, Annan Zhou, Yan Hu, Yuting Gao, Rongrong Chen, Yongming Xia, Shiwei Duan
Pages: 1901-1907
Published online on: 19 February 2016

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Article

Characteristics of CD4+CD25+Foxp3+ regulatory T cells in patients with multiple organ dysfunction syndrome

Xiuxian Zang, Yanfang Jiang, Xiujiang Li, Yujun Du, Junqi Niu
Pages: 1908-1912
Published online on: 15 March 2016

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Article

Endothelial nitric oxide synthase gene polymorphism is associated with Legg-Calvé-Perthes disease

Yulong Zhao, Shijie Liao, Rongbin Lu, Hao Dang, Jinmin Zhao, Xiaofei Ding
Pages: 1913-1917
Published online on: 26 February 2016

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Article

Association between hypoxemia and anemia following arthroplasty: A pilot clinical study

Fuqiang Gao, Wei Sun, Wanshou Guo, Liming Cheng, Zirong Li, Nepali Kush
Pages: 1918-1922
Published online on: 26 February 2016

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Article

Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease

Igor Govorov, Lena Ekelund, Roza Chaireti, Petra Elfvinge, Margareta Holmström, Katarina Bremme, Miriam Mints
Pages: 1923-1929
Published online on: 10 March 2016

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Article

Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis

Tian-Ying Feng, Xue-Feng Han, Rui Lang, Fei Wang, Qiong Wu
Pages: 1930-1936
Published online on: 15 March 2016

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Article

Effect of heart rate on the diagnostic accuracy of 256-slice computed tomography angiography in the detection of coronary artery stenosis: ROC curve analysis

Gang Wang, Yifen Wu, Zhentao Zhang, Xiaolin Zheng, Yulan Zhang, Manqiu Liang, Huanchu Yuan, Haiping Shen, Dewei Li
Pages: 1937-1942
Published online on: 11 March 2016

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Case Report

Giant cystic lymphangioma originating from the cardia of the stomach: A case report

Geng Chen, Mingqing Liu, Tayyab Hamid Malik, Shouying Li, Ying Tang, Hong Xu
Pages: 1943-1946
Published online on: 19 February 2016

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Article

Preventive activity of banana peel polyphenols on CCl4-induced experimental hepatic injury in Kunming mice

Rui Wang, Xia Feng, Kai Zhu, Xin Zhao, Huayi Suo
Pages: 1947-1954
Published online on: 11 March 2016

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Article

Effects of melatonin on liver function and lipid peroxidation in a rat model of hepatic ischemia/reperfusion injury

Wen‑Sheng Deng, Qing Xu, Ye Liu, Chun‑Hui Jiang, Hong Zhou, Lei Gu
Pages: 1955-1960
Published online on: 15 March 2016

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Article

Memory-enhancing effect of aspirin is mediated through opioid system modulation in an AlCl3-induced neurotoxicity mouse model

Saima Rizwan, Ayesha Idrees, Muhammad Ashraf, Touqeer Ahmed
Pages: 1961-1970
Published online on: 11 March 2016

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Article

Manipulations in HIWI level exerts influence on the proliferation of human non-small cell lung cancer cells

Yuguang Wang, Jia Liu, Guangyao Wu, Fang Yang
Pages: 1971-1976
Published online on: 24 February 2016

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Article

Effects of preoperative bromocriptine treatment on prolactin-secreting pituitary adenoma surgery

Yingxiao Cao, Fengju Wang, Zhenbo Liu, Baohua Jiao
Pages: 1977-1982
Published online on: 02 March 2016

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Case Report

Treatment of internal carotid artery dissection with Willis covered stent: A case report of recurrent limb weakness and no response to medical therapy

Xueli Cai, Jianhong Guan, Shaojun Ren, Yixin Wei, Xiao Peng, Weiwen Qiu, Jun Chen
Pages: 1983-1986
Published online on: 26 February 2016

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Article

Effects of carvedilol reduce conjunctivitis through changes in inflammation, NGF and VEGF levels in a rat model

Ying Chen, Xianfei Hong
Pages: 1987-1992
Published online on: 10 March 2016

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Article

Regulatory role of microRNA-30b and plasminogen activator inhibitor-1 in the pathogenesis of cognitive impairment

Xiuqin Li, Yong Gao, Zhaoyun Meng, Cui Zhang, Qinde Qi
Pages: 1993-1998
Published online on: 15 March 2016

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Article

3,4‑Dihydroxyphenylethanol alleviates early brain injury by modulating oxidative stress and Akt and nuclear factor‑κB pathways in a rat model of subarachnoid hemorrhage Retraction in /10.3892/etm.2024.12734

Peng Fu, Quan Hu
Pages: 1999-2004
Published online on: 22 February 2016

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Article

Triptolide reduces the viability of osteosarcoma cells by reducing MKP-1 and Hsp70 expression

Lei Zhao, Bo Jiang, Dong Wang, Wei Liu, Huawu Zhang, Weisheng Liu, Zhen Qiu
Pages: 2005-2010
Published online on: 15 March 2016

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Article

Expression of TGF-β1 and miRNA-145 in patients with diabetic foot ulcers

Fengmei Zhang, Yuguo Ren, Peng Liu, Yufeng Ren, Debao Wang
Pages: 2011-2014
Published online on: 02 March 2016

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Article

Efficacy and safety comparison of DL-3-n-butylphthalide and Cerebrolysin: Effects on neurological and behavioral outcomes in acute ischemic stroke

Li‑Xia Xue, Ting Zhang, Yu‑Wu Zhao, Zhi Geng, Jing‑Jiong Chen, Hao Chen
Pages: 2015-2020
Published online on: 10 March 2016

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Article

Protective effects of thoracic epidural anesthesia on hypoxia-induced acute lung injury in rabbits

Lijun Wang, Jing Cang, Zhanggang Xue
Pages: 2021-2027
Published online on: 11 March 2016

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Article

Assessment of vulnerable and unstable carotid atherosclerotic plaques on endarterectomy specimens

Doina Butcovan, Veronica Mocanu, Dana Baran, Diana Ciurescu, Grigore Tinica
Pages: 2028-2032
Published online on: 19 February 2016

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Article

Neurolytic celiac plexus block enhances skeletal muscle insulin signaling and attenuates insulin resistance in GK rats

Jun Li, Tao Chen, Kun Li, Hongtao Yan, Xiaowei Li, Yun Yang, Yulan Zhang, Bingyin Su, Fuxiang Li
Pages: 2033-2041
Published online on: 19 February 2016

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Article

Possible involvement of AMP‑activated protein kinase in PGE1‑induced synthesis of osteoprotegerin in osteoblasts

Shingo Kainuma, Takanobu Otsuka, Gen Kuroyanagi, Naohiro Yamamoto, Rie Matsushima‑Nishiwaki, Osamu Kozawa, Haruhiko Tokuda
Pages: 2042-2048
Published online on: 22 February 2016

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Article

Role of α-II-spectrin breakdown products in the prediction of the severity and clinical outcome of acute traumatic brain injury

Shangyu Chen, Qiankun Shi, Shuyun Zheng, Liangshen Luo, Shoutao Yuan, Xiang Wang, Zihao Cheng, Wenhao Zhang
Pages: 2049-2053
Published online on: 11 March 2016

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Article

Chlorogenic acid induces apoptosis to inhibit inflammatory proliferation of IL-6-induced fibroblast-like synoviocytes through modulating the activation of JAK/STAT and NF-κB signaling pathways

Lixia Lou, Jingwei Zhou, Yujun Liu, Yi Wei, Jiuli Zhao, Jiagang Deng, Bin Dong, Lingqun Zhu, Aiming Wu, Yingxi Yang, Limin Chai
Pages: 2054-2060
Published online on: 09 March 2016

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Article

Association between the concentration of imatinib in bone marrow mononuclear cells, mutation status of ABCB1 and therapeutic response in patients with chronic myelogenous leukemia

Chang‑Xin Yin, Wei‑Wei Chen, Qing‑Xiu Zhong, Xue‑Jie Jiang, Zhi‑Xiang Wang, Xiao‑Dong Li, Jie‑Yu Ye, Rui Cao, Li‑Bing Liao, Fu‑Qun Wu, Dan Xu, Jian‑Sheng Zhong, Fan‑Yi Meng
Pages: 2061-2065
Published online on: 02 March 2016

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Article

Neonatal hypoglycemic brain injury is a cause of infantile spasms

Guang Yang, Li‑Ping Zou, Jing Wang, Xiuyu Shi, Shuping Tian, Xiaofan Yang, Jun Ju, Hongxiang Yao, Yujie Liu
Pages: 2066-2070
Published online on: 25 February 2016

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Retraction

[Retracted] Expression and clinical significance of the DNA repair enzyme MYH in esophageal squamous cell carcinoma

Kai Shen, Yong Ji, Guo-Qiang Chen, Bin Huang, Xian Zhang, Song Wu, Gui-Ping Yu, Xiao-Chen Wang
Pages: 2071-2071
Published online on: 15 March 2016

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Journal Cover
March-2026 Volume 31 Issue 3

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Article Open Access

Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Article Open Access

Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Article Open Access

Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Article Open Access

Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Article Open Access

Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Article Open Access

Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro-González, Josefina Vegara-Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Case Report Open Access

Postoperative hypofractionated intensity-modulated proton therapy to control recurrent paraganglioma at the jugular foramen: A case report and literature review

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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Article Open Access

No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Article

Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 31 Issue 4

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Impact Factor: 2.3

Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Article Open Access

Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Review Open Access

Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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Article Open Access

PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Review Open Access

Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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