Treatment of patellar instability in a case of hereditary onycho-osteodysplasia (nail-patella syndrome) with medial patellofemoral ligament reconstruction: A case report

Gong,Yubao; Yang,Chen; Liu,Yang; Liu,Jianguo; Qi,Xin

doi:10.3892/etm.2016.3180

June-2016 Volume 11 Issue 6

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June-2016 Volume 11 Issue 6

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Case Report

Treatment of patellar instability in a case of hereditary onycho-osteodysplasia (nail-patella syndrome) with medial patellofemoral ligament reconstruction: A case report

Authors:
- Yubao Gong
- Chen Yang
- Yang Liu
- Jianguo Liu
- Xin Qi
View Affiliations / Copyright

Affiliations: Department of Bone and Joint Surgery, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of Radiology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China
Pages: 2361-2364
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Published online on: March 23, 2016

https://doi.org/10.3892/etm.2016.3180
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Abstract

Hereditary onycho-osteodysplasia, also known as nail-patella syndrome (NPS), is a rare genetic disorder that is primarily characterized by poorly developed nails and patella. Patients with NPS frequently suffer from patellar instability that requires surgical management. The present case report describes a 25‑year‑old man with NPS. The patient presented with left knee pain and was found to have recurrent left patellar dislocation. The knee pain was first reported 1‑year after a minor knee trauma incident. Following complete evaluation, a diagnosis of NPS was reached. The patient underwent surgical intervention using medial patellofemoral ligament (MPFL) reconstruction with a gracilis tendon autograft looped through two transverse 3.2‑mm drill holes in the patella and fixed at the natural MPFL insertion site on the medial femoral condyle with an interference screw. The surgery resulted in stabilization of the patella in the femoral trochlea and the patient did not have any subsequent dislocations or subluxations. The patient had an excellent range of knee movement in the follow‑up period. This case indicates that MPFL reconstruction in patients with patellar dislocation secondary to NPS can successfully restore normal patellar tracking and result in good range of movement and functional activity.

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1	Sweeney E, Fryer A, Mountford R, Green A and McIntosh I: Nail patella syndrome: A review of the phenotype aided by developmental biology. J Med Genet. 40:153–162. 2003. View Article : Google Scholar : PubMed/NCBI
2	Romero P, Sanhueza F, Lopez P, Reyes L and Herrera L: c.194 A>C (Q65P) mutation in the LMX1B gene in patients with nail-patella syndrome associated with glaucoma. Mol Vis. 17:1929–1939. 2011.PubMed/NCBI
3	Witzgall R: How are podocytes affected in nail-patella syndrome? Pediatr Nephrol. 23:1017–1020. 2008. View Article : Google Scholar : PubMed/NCBI
4	Granata A, Nori G, Ravazzolo R, Marini M, Castellino S, Sicurezza E, Fiore CE and Mignani R: Nail-patella syndrome and renal involvement. Description of three cases and literature review. Clin Nephrol. 69:377–382. 2008. View Article : Google Scholar : PubMed/NCBI
5	Turner JW: An hereditary arthrodysplasia associated with hereditary dystrophy of the nails. JAMA. 100:882–884. 1933. View Article : Google Scholar
6	Choczaj-Kukula, A and Janniger CK: Nail-patella syndrome. In emedicine: WebMD. http://emedicine.medscape.com/article/1106294-clinical#b4August 22–2014.
7	Scuderi G, Cuomo F and Scott WN: Lateral release and proximal realignment for patellar subluxation and dislocation. A long-term follow-up. J Bone Joint Surg Am. 70:856–861. 1988.PubMed/NCBI
8	Brown DE, Alexander AH and Lichtman DM: The Elmslie-Trillat procedure: Evaluation in patellar dislocation and subluxation. Am J Sports Med. 12:104–109. 1984. View Article : Google Scholar : PubMed/NCBI
9	Shelbourne KD, Porter DA and Rozzi W: Use of a modiﬁed Elmslie-Trillat procedure to improve abnormal patellar congruence angle. Am J Sports Med. 22:318–323. 1994. View Article : Google Scholar : PubMed/NCBI
10	Peterson L, Karlsson J and Brittberg M: Patellar instability with recurrent dislocation due to patellofemoral dysplasia. Results after surgical treatment. Bull Hosp Jt Dis Orthop Inst. 48:130–139. 1988.PubMed/NCBI
11	Christiansen SE, Jacobsen BW, Lund B and Lind M: Reconstruction of the medial patellofemoral ligament with gracilis tendon autograft in transverse patellar drill holes. Arthroscopy. 24:82–87. 2008. View Article : Google Scholar : PubMed/NCBI
12	Brixey AM Jr and Burke RM: Arthro-onychodysplasia; hereditary syndrome involving deformity of head of radius, absence of patellas, posterior iliac spurs, dystrophy of finger nails. Am J Med. 8:738–744. 1950. View Article : Google Scholar : PubMed/NCBI
13	Lind M, Jakobsen BW, Lund B and Christiansen SE: Reconstruction of the medial patellofemoral ligament for treatment of patellar instability. Acta Orthop. 79:354–360. 2008. View Article : Google Scholar : PubMed/NCBI
14	Feller JA, Amis AA, Andrish JT, Arendt EA, Erasmus PJ and Powers CM: Surgical biomechanics of the patellofemoral joint. Arthroscopy. 23:542–553. 2007. View Article : Google Scholar : PubMed/NCBI
15	Steensen RN, Dopirak RM and Maurus PB: Minimally invasive “crescentic” imbrication of the medial patellofemoral ligament for chronic patellar subluxation. Arthroscopy. 21:371–375. 2005. View Article : Google Scholar : PubMed/NCBI
16	Sillanpää PJ, Mäenpää HM, Mattila VM, Visuri T and Pihlajamäki H: A mini-invasive adductor magnus tendon transfer technique for medial patellofemoral ligament reconstruction: a technical note. Knee Surg Sports Traumatol Arthrosc. 17:508–512. 2009. View Article : Google Scholar : PubMed/NCBI
17	Gomes Ellera JL: Medial patellofemoral ligament reconstruction for recurrent dislocation of the patella: a preliminary report. Arthroscopy. 8:335–340. 1992. View Article : Google Scholar : PubMed/NCBI
18	Deie M, Ochi M, Sumen Y, Yasumoto M, Kobayashi K and Kimura H: Reconstruction of the medial patellofemoral ligament for the treatment of habitual or recurrent dislocation of the patella in children. J Bone Joint Surg Br. 85:887–890. 2003.PubMed/NCBI
19	Sillanpää PJ and Arendt E: Reconstruction of the medial patellofemoral ligament using the adductor magnus tendon. Arthroscopy. 28:1749–1750. 2012. View Article : Google Scholar : PubMed/NCBI
20	Arendt EA: MPFL reconstruction for PF instability. The soft (tissue) approach. Orthop Traumatol Surg Res. 95(Suppl 1): S97–S100. 2009. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Treatment of patellar instability in a case of hereditary onycho-osteodysplasia (nail-patella syndrome) with medial patellofemoral ligament reconstruction: A case report

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Abstract

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