Thrombotic thrombocytopenic purpura (TPP) successfully rescued by plasma exchange in the ICU: A report of two cases

Zou,Xiuli; Wu,Tiejun; Zhang,Xihong; Qu,Aijun; Tian,Suochen

doi:10.3892/etm.2016.3265

July-2016 Volume 12 Issue 1

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July-2016 Volume 12 Issue 1

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Article

Thrombotic thrombocytopenic purpura (TPP) successfully rescued by plasma exchange in the ICU: A report of two cases

Authors:
- Xiuli Zou
- Tiejun Wu
- Xihong Zhang
- Aijun Qu
- Suochen Tian
View Affiliations / Copyright

Affiliations: Intensive Care Unit, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China
Pages: 329-332
|
Published online on: April 18, 2016

https://doi.org/10.3892/etm.2016.3265
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Abstract

Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder, which is characterized by thrombus formation in small blood vessels. The present study retrospectively analyzed the clinical data from two patients with severe TTP, who were treated successfully in the intensive care unit (ICU) at the Liaocheng People's Hospital in 2013. Comprehensive therapies were administered to the patients, including plasma exchange (PE), mechanical ventilation (case 1 only), steroid therapy, blood transfusion and anti-inflammatory treatment (case 2 only). The two patients returned to a stable state and were transferred back to the hematology department following PE. The positive outcome achieved for these patients suggests that early intervention involving bedside PE in the ICU may reduce the mortality rate of patients with severe TTP who have concurrent respiratory or circulatory failure and cannot be treated in the dialysis unit.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Thrombotic thrombocytopenic purpura (TPP) successfully rescued by plasma exchange in the ICU: A report of two cases

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