|
1.
|
Li ZQ, Rong XY, Liu YJ, Ni C, Tian XS, Mo
N, Chui DH and Guo XY: Activation of the canonical nuclear
factor-κB pathway is involved in isoflurane-induced hippocampal
interleukin-1β elevation and the resultant cognitive deficits in
aged rats. Biochem Biophys Res Commun. 438:628–634. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
2.
|
Cao Y, Ni C, Li Z, Li L, Liu Y, Wang C,
Zhong Y, Cui D and Guo X: Isoflurane anesthesia results in
reversible ultrastructure and occludin tight junction protein
expression changes in hippocampal blood-brain barrier in aged rats.
Neurosci Lett. 587:51–56. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
3.
|
Jevtovic-Todorovic V, Absalom AR, Blomgren
K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold
KF, Loepke AW, et al: Anaesthetic neurotoxicity and
neuroplasticity: an expert group report and statement based on the
BJA Salzburg Seminar. Br J Anaesth. 111:143–151. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
4.
|
Rappaport BA, Suresh S, Hertz S, Evers AS
and Orser BA: Anesthetic neurotoxicity-clinical implications of
animal models. N Engl J Med. 372:796–797. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
5.
|
Zurek AA, Yu J, Wang DS, Haffey SC,
Bridgwater EM, Penna A, Lecker I, Lei G, Chang T, Salter EW, et al:
Sustained increase in α5GABAA receptor function impairs memory
after anesthesia. J Clin Invest. 124:5437–5441. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
6.
|
Shipton OA and Paulsen O: GluN2A and
GluN2B subunit-containing NMDA receptors in hippocampal plasticity.
Philos Trans R Soc Lond B Biol Sci. 369:201301632013. View Article : Google Scholar : PubMed/NCBI
|
|
7.
|
Lee YS and Silva AJ: The molecular and
cellular biology of enhanced cognition. Nat Rev Neurosci.
10:126–40. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
8.
|
Rammes G, Starker LK, Haseneder R,
Berkmann J, Plack A, Zieglgänsberger W, Ohl F, Kochs EF and Blobner
M: Isoflurane anaesthesia reversibly improves cognitive function
and long-term potentiation (LTP) via an up-regulation in NMDA
receptor 2B subunit expression. Neuropharmacology. 56:626–636.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
9.
|
Mawhinney LJ, de Rivero Vaccari JP, Alonso
OF, Jimenez CA, Furones C, Moreno WJ, Lewis MC, Dietrich WD and
Bramlett HM: Isoflurane/nitrous oxide anesthesia induces increases
in NMDA receptor subunit NR2B protein expression in the aged rat
brain. Brain Res. 1431:23–34. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
10.
|
Chi H, Kawano T, Tamura T, Iwata H,
Takahashi Y, Eguchi S, Yamazaki F, Kumagai N and Yokoyama M:
Postoperative pain impairs subsequent performance on a spatial
memory task via effects on N-methyl-D-aspartate receptor in aged
rats. Life Sci. 93:986–993. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
11.
|
Wang WY, Jia LJ, Luo Y, Zhang HH, Cai F,
Mao H, Xu WC, Fang JB, Peng ZY, Ma ZW, et al: Location- and
subunit-specific NMDA receptors determine the developmental
sevoflurane neurotoxicity through ERK1/2 signaling. Mol Neurobiol.
53:216–230. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
12.
|
Liu J, Zhang X, Zhang W, Gu G and Wang P:
Effects of sevoflurane on young male adult C57BL/6 mice spatial
cognition. PLoS One. 10:e01342172015. View Article : Google Scholar : PubMed/NCBI
|
|
13.
|
Ivanov A, Pellegrino C, Rama S, Dumalska
I, Salyha Y, Ben-Ari Y and Medina I: Opposing role of synaptic and
extrasynaptic NMDA receptors in regulation of the extracellular
signal-regulated kinases (ERK) activity in cultured rat hippocampal
neurons. J Physiol. 572:789–798. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
14.
|
Hardingham GE and Bading H: Synaptic
versus extrasynaptic NMDA receptor signalling: Implications for
neurodegenerative disorders. Nat Rev Neurosci. 11:682–696. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
15.
|
Soria FN, Pérez-Samartín A, Martin A, Gona
KB, Llop J, Szczupak B, Chara JC, Matute C and Domercq M:
Extrasynaptic glutamate release through cystine/glutamate
antiporter contributes to ischemic damage. JClin Invest.
124:3645–3655. 2014. View
Article : Google Scholar
|
|
16.
|
Zhang X, Xin X, Dong Y, Zhang Y, Yu B, Mao
J and Xie Z: Surgical incision-induced nociception causes cognitive
impairment and reduction in synaptic NMDA receptor 2B in mice. J
Neurosci. 33:17737–17748. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
17.
|
Goebel-Goody SM, Davies KD, Alvestad
Linger RM, Freund RK and Browning MD: Phospho-regulation of
synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult
hippocampal slices. Neuroscience. 158:1446–1459. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18.
|
Hudson AE and Hemmings HC Jr: Are
anaesthetics toxic to the brain? Br J Anaesth. 107:30–7. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
19.
|
Rappaport BA, Suresh S , Hertz S, Evers AS
and Orser BA: Anesthetic neurotoxicity-clinical implications of
animal models. N Engl J Med. 372:796–7. 2015.
|
|
20.
|
Brambrink AM, Orfanakis A and Kirsch JR:
Anesthetic neurotoxicity. Anesthesiol Clin. 30:207–228. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
21.
|
Moller JT, Cluitmans P, Rasmussen LS, Houx
P, Rasmussen H, Canet J, Rabbitt P, Jolles J, Larsen K, Hanning CD,
et al: Long-term postoperative cognitive dysfunction in the elderly
ISPOCD1 study. ISPOCD investigators. International study of
post-operative cognitive dysfunction. Lancet. 351:857–861. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
22.
|
Newman S, Stygall J, Hirani S, Shaefi S
and Maze M: Postoperative cognitive dysfunction after noncardiac
surgery: A systematic review. Anesthesiology. 106:572–590. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
23.
|
Nadelson MR, Sanders RD and Avidan MS:
Perioperative cognitive trajectory in adults. Br J Anaesth.
112:440–451. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24.
|
Stratmann G, Sall JW, Bell JS, Alvi RS,
May L, Ku B, Dowlatshahi M, Dai R, Bickler PE, Russell I, et al:
Isoflurane does not affect brain cell death, hippocampal
neurogenesis, or long-term neurocognitive outcome in aged rats.
Anesthesiology. 112:305–315. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
25.
|
Liu H and Weng H: Up-regulation of
Alzheimer's disease-associated proteins may cause enflurane
anesthesia induced cognitive decline in aged rats. Neurol Sci.
35:185–189. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
26.
|
Selkoe DJ: Alzheimer's disease is a
synaptic failure. Science. 298:789–791. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
27.
|
Arendt T: Synaptic degeneration in
Alzheimer's disease. Acta Neuropathol. 118:167–179. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
28.
|
Querfurth HW and LaFerla FM: Alzheimer's
disease. N Engl J Med. 362:329–344. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29.
|
Shipton OA, Leitz JR, Dworzak J, Acton CE,
Tunbridge EM, Denk F, Dawson HN, Vitek MP, Wade-Martins R, Paulsen
O, et al: Tau protein is required for amyloid {beta}-induced
impairment of hippocampal long-term potentiation. J Neurosci.
31:1688–1692. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
30.
|
Pooler AM, Noble W and Hanger DP: A role
for tau at the synapse in Alzheimer's disease pathogenesis.
Neuropharmacology. 76(Pt A): 1–8. 2014.doi:
10.1016/j.neuropharm.2013.09.018. View Article : Google Scholar : PubMed/NCBI
|
|
31.
|
Parsons MP and Raymond LA: Extrasynaptic
NMDA receptor involvement in central nervous system disorders.
Neuron. 82:279–293. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
32.
|
Nagy J: The NR2B subtype of NMDA receptor:
a potential target for the treatment of alcohol dependence. Curr
Drug Targets CNS Neurol Disord. 3:169–179. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
33.
|
Ming Z, Griffith BL, Breese GR, Mueller RA
and Criswell HE: Changes in the effect of isoflurane on
N-methyl-D-aspartic acid-gated currents in cultured cerebral
cortical neurons with time in culture: evidence for subunit
specificity. Anesthesiology. 97:856–867. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
34.
|
Liu DD, Yang Q and Li ST: Activation of
extrasynaptic NMDA receptors induces LTD in rat hippocampal CA1
neurons. Brain Res Bull. 93:10–16. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35.
|
Li S, Jin M, Koeglsperger T, Shepardson
NE, Shankar GM and Selkoe DJ: Soluble Aβ oligomers inhibit
long-term potentiation through a mechanism involving excessive
activation of extrasynaptic NR2B-containing NMDA receptors. J
Neurosci. 31:6627–6638. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
36.
|
Tang YP, Shimizu E, Dube GR, Rampon C,
Kerchner GA, Zhuo M, Liu G and Tsien JZ: Genetic enhancement of
learning and memory in mice. Nature. 401:63691999.
|
|
37.
|
Hawasli AH, Benavides DR, Nguyen C, Kansy
JW, Hayashi K, Chambon P, Greengard P, Powell CM, Cooper DC and
Bibb JA: Cyclin-dependent kinase 5 governs learning and synaptic
plasticity via control of NMDAR degradation. Nat Neurosci.
10:880–886. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
38.
|
Zhao X, Rosenke R, Kronemann D, Brim B,
Das SR, Dunah AW and Magnusson KR: The effects of aging on
N-methyl-D-aspartate receptor subunits in the synaptic membrane and
relationships to long-term spatial memory. Neuroscience.
162:933–945. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
39.
|
Chen BS and Roche KW: Regulation of NMDA
receptors by phosphorylation. Neuropharmacology. 53:3622007.
View Article : Google Scholar : PubMed/NCBI
|
|
40.
|
Pehar M, Ko MH, Li M, Scrable H and
Puglielli L: P44, the ‘longevity-assurance’ isoform of P53,
regulates tau phosphorylation and is activated in an age-dependent
fashion. Aging Cell. 13:449–456. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
41.
|
Song WJ, Son MY, Lee HW, Seo H, Kim JH and
Chung SH: Enhancement of BACE1 activity by p25/Cdk5-mediated
phosphorylation in Alzheimer's disease. PLoS One. 10:e01369502015.
View Article : Google Scholar : PubMed/NCBI
|
|
42.
|
Wang WY, Luo Y, Jia LJ, Hu SF, Lou XK,
Shen SL, Lu H, Zhang HH, Yang R, Wang H, et al: Inhibition of
aberrant cyclin-dependent kinase 5 activity attenuates isoflurane
neurotoxicity in the developing brain. Neuropharmacology. 77:90–99.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
43.
|
Zhang S, Edelmann L, Liu J, Crandall JE
and Morabito MA: Cdk5 regulates the phosphorylation of tyrosine
1472 NR2B and the surface expression of NMDA receptors. J Neurosci.
28:415–424. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
44.
|
Sato S, Xu J, Okuyama S, Martinez LB,
Walsh SM, Jacobsen MT, Swan RJ, Schlautman JD, Ciborowski P and
Ikezu T: Spatial learning impairment, enhanced CDK5/p35 activity,
and downregulation of NMDA receptor expression in transgenic mice
expressing tau-tubulin kinase 1. J Neurosci. 28:14511–14521. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
45.
|
Plattner F, Hernández A, Kistler TM, Pozo
K, Zhong P, Yuen EY, Tan C, Hawasli AH, Cooke SF, Nishi A, et al:
Memory enhancement by targeting Cdk5 regulation of NR2B. Neuron.
81:1070–1083. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
46.
|
Howland JG and Cazakoff BN: Effects of
acute stress and GluN2B-containing NMDA receptor antagonism on
object and object-place recognition memory. Neurobiol Learn Mem.
93:261–267. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
47.
|
Ge Y, Dong Z, Bagot RC, Howland JG,
Phillips AG, Wong TP and Wang YT: Hippocampal long-term depression
is required for the consolidation of spatial memory. Proc Natl Acad
Sci USA. 107:16697–16702. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
48.
|
Mathur P, Graybeal C, Feyder M, Davis MI
and Holmes A: Fear memory impairing effects of systemic treatment
with the NMDA NR2B subunit antagonist, Ro 25–6981, in mice:
attenuation with ageing. Pharmacol Biochem Behav. 91:453–460. 2009.
View Article : Google Scholar : PubMed/NCBI
|
