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Application of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis

  • Authors:
    • Zhongwei Li
    • Naikun Li
    • Yanyan Qu
    • Feng Gai
    • Guowei Zhang
    • Guanghui Zhang
  • View Affiliations / Copyright

    Affiliations: CT Room, Yantaishan Hospital, Yantai, Shandong 264001, P.R. China, Department of Medical Imaging, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China, Department of Endocrinology, Yantaishan Hospital, Yantai, Shandong 264001, P.R. China, Department of Radiology, Yantai Municipal Laiyang Central Hospital, Yantai, Shandong 265200, P.R. China
    Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 297-301
    |
    Published online on: May 9, 2016
       https://doi.org/10.3892/etm.2016.3318
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Abstract

The application value of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis was evaluated. A total of 58 cases of transient ischemic attack (TIA) and 60 cases of ischemic cerebral apoplexy cases were selected. The cases were analysed using a GE Healthcare Signa HDx 3.0T superconducting whole‑body magnetic resonance scan within 24 h of attack. Eight‑channel head phased array coils and conventional sequence were used to create T1‑weighted images (T1WI), T2WI, diffusion‑weighted imaging, magnetic resonance angiography (MRA) and ASL imaging, which were generated into ASL pseudo‑color images (blue was hypoperfusion area) through post-processing in order to compare and analyze the correlation and differences between ASL and conventional imaging in terms of lesion location, size, blood perfusion situation and signal range of relative cerebral blood flow (rCBF). The results showed that, 13 TIA cases of abnormal signal in conventional magnetic resonance imaging (MRI) can also be found through ASL technology. Diameter stenosis beyond 30% in MRA can also be tested in ASL. A positive rate in ASL was significantly higher than that of conventional MRI (χ2=29.078, P<0.001) and hypoperfusion area was greatly increased (t=32.526, P<0.001). The rCBF value was positively correlated with the degree of diameter stenosis shown in MRA (r=0.524, P=0.012). Additionally, the positive rate of ASL was positively correlated with the attack times of TIA (r=0.352, P=0.027). A total of 39 cerebral apoplexy cases of abnormal signal in conventional MRI were also found through ASL technology. A positive rate in ASL was significantly higher than that of conventional MRI (χ2=7.685, P=0.006) and hypoperfusion area was greatly increased (t=9.425, P<0.001). The rCBF value was positively correlated with the degree of diameter stenosis (r=0.635, P=0.009). In conclusion, 3.0T ASL correlated with early diagnosis of TIA and mild and moderate intracranial arterial stenosis of cerebral apoplexy.
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Copy and paste a formatted citation
Spandidos Publications style
Li Z, Li N, Qu Y, Gai F, Zhang G and Zhang G: Application of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis. Exp Ther Med 12: 297-301, 2016.
APA
Li, Z., Li, N., Qu, Y., Gai, F., Zhang, G., & Zhang, G. (2016). Application of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis. Experimental and Therapeutic Medicine, 12, 297-301. https://doi.org/10.3892/etm.2016.3318
MLA
Li, Z., Li, N., Qu, Y., Gai, F., Zhang, G., Zhang, G."Application of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis". Experimental and Therapeutic Medicine 12.1 (2016): 297-301.
Chicago
Li, Z., Li, N., Qu, Y., Gai, F., Zhang, G., Zhang, G."Application of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis". Experimental and Therapeutic Medicine 12, no. 1 (2016): 297-301. https://doi.org/10.3892/etm.2016.3318
Copy and paste a formatted citation
x
Spandidos Publications style
Li Z, Li N, Qu Y, Gai F, Zhang G and Zhang G: Application of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis. Exp Ther Med 12: 297-301, 2016.
APA
Li, Z., Li, N., Qu, Y., Gai, F., Zhang, G., & Zhang, G. (2016). Application of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis. Experimental and Therapeutic Medicine, 12, 297-301. https://doi.org/10.3892/etm.2016.3318
MLA
Li, Z., Li, N., Qu, Y., Gai, F., Zhang, G., Zhang, G."Application of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis". Experimental and Therapeutic Medicine 12.1 (2016): 297-301.
Chicago
Li, Z., Li, N., Qu, Y., Gai, F., Zhang, G., Zhang, G."Application of 3.0T magnetic resonance arterial spin labeling (ASL) technology in mild and moderate intracranial atherosclerotic stenosis". Experimental and Therapeutic Medicine 12, no. 1 (2016): 297-301. https://doi.org/10.3892/etm.2016.3318
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