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Article

Evaluation of transvaginal sonography in detecting endometrial polyps and the pregnancy outcome following hysteroscopic polypectomy in infertile women

  • Authors:
    • Huili Zhu
    • Jing Fu
    • Haike Lei
    • Yong Song
    • Licong Shen
    • Wei Huang
  • View Affiliations / Copyright

    Affiliations: Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
  • Pages: 1196-1200
    |
    Published online on: May 31, 2016
       https://doi.org/10.3892/etm.2016.3407
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Abstract

The aims of the present study were to evaluate the effectiveness of transvaginal sonography (TVS) in the detection of endometrial polyps (EPs), and to assess the pregnancy outcome in infertile women following hysteroscopic polypectomy. A total of 145 women diagnosed with primary or secondary infertility and intrauterine disorders by TVS and hysterosalpingography (HSG) were included in the current study. All subjects were divided into three groups based on hysteroscopic findings, including the EP, intrauterine adhesion and normal groups. EPs were removed for biopsy and intrauterine adhesions were treated. Pregnancy rates between groups were compared. In total, 34 EPs were detected by TVS, while 45 subjects were later confirmed with EP by hysteroscopy. The sensitivity, specificity, positive predictive value and negative predictive value of TVS in the detection of EPs were 67, 96, 88.23 and 86.49%, respectively. Of the included patients, 120 subjects were followed up, including 40 patients diagnosed with EPs, 42 with intrauterine adhesions and 38 with normal cavities. The results indicated no statistically significant differences in the age, type and duration of infertility, least function (LF) score and classification of the extent of tubal disease with the distal fimbrial obstruction between the three groups. In addition, pregnancy rate and spontaneous abortion rate in the EP group following hysteroscopic polypectomy were 45 and 5.6%, respectively. No significant difference was observed in the fertility rate following surgery. In conclusion, TVS features high sensitivity, specificity and certain unique sonographic characteristics in diagnosing EPs, and may be used as a preliminary diagnostic procedure to select patients for hysteroscopy. Furthermore, hysteroscopic polypectomy is an important approach for the treatment of infertile patients with EPs and appears to help increase the pregnancy rate of previously infertile women.
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1 

Valle RF: Therapeutic hysteroscopy in infertility. Int J Fertil. 29:143–148. 1984.PubMed/NCBI

2 

Bakour SH, Khan KS and Gupta JK: The risk of premalignant and malignant pathology in endometrial polyps. Acta Obstet Gynecol Scand. 81:182–183. 2002. View Article : Google Scholar : PubMed/NCBI

3 

Tanos V: Endometrial polyps and infertility. Reproductive Surgery in Assisted Conception. Metwally M and Li TC: Springer London. (London). 219–221. 2015.

4 

Bocca SM: Endometrial polyps. Ultrasound Imaging in Reproductive Medicine. Stadmauer LA and Tur-Kaspa I: Springer London. (London). 133–149. 2014. View Article : Google Scholar

5 

Lass A, Williams G, Abusheikha N and Brinsden P: The effect of endometrial polyps on outcomes of in vitro fertilization (IVF) cycles. J Assist Reprod Genet. 16:410–415. 1999. View Article : Google Scholar : PubMed/NCBI

6 

Shen L, Wang Q, Huang W, Wang Q, Yuan Q, Huang Y and Lei H: High prevalence of endometrial polyps in endometriosis-associated infertility. Fertil Steril. 95:2722–2724. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Haider Z, Alkatib M, Syed A and Bourne T: Transvaginal scan (TVS) versus TVS and saline infusion hydrosonography for the diagnosis of endometrial polyps and submucous fibroids. BJOG. 113:868. 2006.

8 

Gao YY, Xin YL, Wei XQ, Hou QN and Zhang CL: A study on the diagnostic value of three examination methods for endometrial polyps in patients with infertility. Xian Dai Sheng Wu Yi Xue Jin Zhan. 15:3053–3057. 2015.(In Chinese).

9 

Farquhar C, Ekeroma A, Furness S and Arrol B: A systematic review of transvaginal ultrasonography, sonohysterography and hysteroscopy for the investigation of abnormal uterine bleeding in premnopausal women. Acta Obstet Gynecol Scand. 82:493–504. 2003. View Article : Google Scholar : PubMed/NCBI

10 

Timmermans A, Gerritse MB, Opmeer BC, Jansen FW, Mol BW and Veersema S: Diagnostic accuracy of endometrial thickness to exclude polyps in women with postmenopausal bleeding. J Clin Ultrasound. 36:286–290. 2008. View Article : Google Scholar : PubMed/NCBI

11 

Dueholm M, Jensen ML, Laursen H and Kracht P: Can the endometrial thickness as measured by trans-vaginal sonography be used to exclude polyps or hyperplasia in pre-menopausal patients with abnormal uterine bleeding? Acta Obstet Gynecol Scand. 80:645–651. 2001. View Article : Google Scholar : PubMed/NCBI

12 

Song Y, Shen LC, Huang W, Lei HK, Wang QS and Zhu HL: Diagnostic value of endometrial thickness determined by transvaginal sonography in infertile women with endometrial polyps. Chin Med J (Engl). 125:2279–2283. 2012.PubMed/NCBI

13 

Balić D: Balić: Office hysteroscopy, transvaginal ultrasound and endometrial histology: A comparison in infertile patients. Acta Medica Academica. 40:34–38. 2011. View Article : Google Scholar

14 

Roma Dalfó A, Ubeda B, Ubeda A, Monzón M, Rotger R, Ramos R and Placio A: Diagnostic value of hysterosalpingography in the detection of intrauterine abnormalities: A comparison with hysteroscopy. American Journal of Roentgenology. 183:1405–1409. 2004. View Article : Google Scholar : PubMed/NCBI

15 

Adamson GD and Pasta DJ: Pregnancy rates can be predicted by validated endometriosis fertility index (EFI). Fertil Steril. 77(Suppl 1): S482002. View Article : Google Scholar

16 

Rock JA, Katayama KP, Martin EJ, Woodruff JD and Jones HW Jr: Factors influencing the success of salpingostomy techniques for distal fimbrial obstruction. Obstet Gynecol. 52:591–596. 1978.PubMed/NCBI

17 

de Jong P, Doel F and Falconer A: Outpatient diagnostic hysteroscopy. Br J Obstet Gynaecol. 97:299–303. 1990. View Article : Google Scholar : PubMed/NCBI

18 

Granberg S, Wickland M, Karlsson B, Norström A and Friberg LG: Endometrial thickness as measured by endovaginal ultrasonography for indetifying endometrial abnormality. Am J Obstet Gynecol. 164:47–52. 1991. View Article : Google Scholar : PubMed/NCBI

19 

Shalev J, Meizner I, Bar-Hava I, Dicker D, Mashiach R and Ben-Rafael Z: Predictive value of transvaginal value of transvaginal sonography performed before routing diagnostic hyseroscopy for evaluation of infertility. Fertil Steril. 73:412–417. 2000. View Article : Google Scholar : PubMed/NCBI

20 

Yantapant A: Comparison of the accuracy of transvaginal sonography and hysteroscopy for the diagnosis of endometrial polyps at Rajavithi Hospital. J Med Assoc Thai. 95(Suppl 3): S92–S97. 2012.PubMed/NCBI

21 

Vitner D, Filmer S, Goldstein I, Khatib N and Weiner Z: A comparison between ultrasonography and hysteroscopy in the diagnosis of uterine pathology. Eur J Obstet Gynecol Reprod Biol. 171:143–145. 2013. View Article : Google Scholar : PubMed/NCBI

22 

Mendelson EB, Bohm-Velez M, Josef N and Neiman HL: Endometrial abnormalities: Evaluation with transvaginal sonography. AJR Am J Roentgenol. 150:139–142. 1988. View Article : Google Scholar : PubMed/NCBI

23 

Ahmadi F, Rashidy Z, Haghighi H, Akhoond M, Niknejadi M, Hemat M and Shamsipour M: Uterine cavity assessment in infertile women: Sensitivity and specificity of three-dimensional hysterosonography versus hysteroscopy. Iran J Reprod Med. 11:977–982. 2013.PubMed/NCBI

24 

De Placido G, Clarizia R, Cadente C, Castaldo G, Romano C, Mollo A, Alviggi C and Conforti S: Compliance and diagnostic efficacy of mini-hysteroscopy versus traditional hysteroscopy in infertility investigation. Eu J Obstet Gynecol Reprod Biol. 135:83–87. 2007. View Article : Google Scholar

25 

Silló-Seidl G: The analysis of the endometrium of 1,000 sterile women. Hormones. 2:70–75. 1971.PubMed/NCBI

26 

Hereter L, Carreras O, Pascual MA, Martinez F and Barri PN: Repercussion of the presence of endometrial polyps in an I.V.F. cycle. Minerva Medica. 29:1071–1074. 1998.

27 

Varasteh NN, Neuwirth RS, Levin B and Keltz MD: Pregnancy rates after hysteroscopic polypectomy and myomectomy in infertile women. Obstet Gynecol. 94:168–171. 1999. View Article : Google Scholar : PubMed/NCBI

28 

Spiewankiewicz B, Stelmachów J, Sawicki W, Cendrowski K, Wypych P and Swiderska K: The effectiveness of hysteroscopic polypectomy in cases of female infertility. Clin Exp Obstet Gynecol. 30:23–25. 2003.PubMed/NCBI

29 

Stamatellos I, Apostolides A, Stamatopoulos P and Bontis J: Pregnancy rates after hysteroscopic polypectomy depending on the size or number of the polyps. Arch Gynecol Obstet. 277:395–399. 2008. View Article : Google Scholar : PubMed/NCBI

30 

Pérez-Medina T, Bajo-Arenas J, Salazar F, Redondo T, Sanfrutos L, Alvarez P and Engels V: Endometrial polyps and their implication in the pregnancy rates of patients undergoing intrauterine insemination: A prospective, randomized study. Hum Reprod. 20:1632–1635. 2005. View Article : Google Scholar : PubMed/NCBI

31 

Fernandez H, Sefrioui O, Virelizier C, Gervaise A, Gomel V and Frydman R: Hysteroscopic resection of submucosal myomas in patients with infertility. Hum Reprod. 16:1489–1492. 2001. View Article : Google Scholar : PubMed/NCBI

32 

Shoekir TA, Shalan HM and El Shafei MM: Significance of endometrial polyps detected hysteroscopically in eumenorrhoeic infertile women. J Obstet Gynaecol Res. 30:84–89. 2004. View Article : Google Scholar : PubMed/NCBI

33 

Preutthipan S and Herabutya Y: Hysteroscopic polypectomy in 240 premenopausal and postmenopausal women. Fertil Steril. 83:705–709. 2005. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhu H, Fu J, Lei H, Song Y, Shen L and Huang W: Evaluation of transvaginal sonography in detecting endometrial polyps and the pregnancy outcome following hysteroscopic polypectomy in infertile women. Exp Ther Med 12: 1196-1200, 2016.
APA
Zhu, H., Fu, J., Lei, H., Song, Y., Shen, L., & Huang, W. (2016). Evaluation of transvaginal sonography in detecting endometrial polyps and the pregnancy outcome following hysteroscopic polypectomy in infertile women. Experimental and Therapeutic Medicine, 12, 1196-1200. https://doi.org/10.3892/etm.2016.3407
MLA
Zhu, H., Fu, J., Lei, H., Song, Y., Shen, L., Huang, W."Evaluation of transvaginal sonography in detecting endometrial polyps and the pregnancy outcome following hysteroscopic polypectomy in infertile women". Experimental and Therapeutic Medicine 12.2 (2016): 1196-1200.
Chicago
Zhu, H., Fu, J., Lei, H., Song, Y., Shen, L., Huang, W."Evaluation of transvaginal sonography in detecting endometrial polyps and the pregnancy outcome following hysteroscopic polypectomy in infertile women". Experimental and Therapeutic Medicine 12, no. 2 (2016): 1196-1200. https://doi.org/10.3892/etm.2016.3407
Copy and paste a formatted citation
x
Spandidos Publications style
Zhu H, Fu J, Lei H, Song Y, Shen L and Huang W: Evaluation of transvaginal sonography in detecting endometrial polyps and the pregnancy outcome following hysteroscopic polypectomy in infertile women. Exp Ther Med 12: 1196-1200, 2016.
APA
Zhu, H., Fu, J., Lei, H., Song, Y., Shen, L., & Huang, W. (2016). Evaluation of transvaginal sonography in detecting endometrial polyps and the pregnancy outcome following hysteroscopic polypectomy in infertile women. Experimental and Therapeutic Medicine, 12, 1196-1200. https://doi.org/10.3892/etm.2016.3407
MLA
Zhu, H., Fu, J., Lei, H., Song, Y., Shen, L., Huang, W."Evaluation of transvaginal sonography in detecting endometrial polyps and the pregnancy outcome following hysteroscopic polypectomy in infertile women". Experimental and Therapeutic Medicine 12.2 (2016): 1196-1200.
Chicago
Zhu, H., Fu, J., Lei, H., Song, Y., Shen, L., Huang, W."Evaluation of transvaginal sonography in detecting endometrial polyps and the pregnancy outcome following hysteroscopic polypectomy in infertile women". Experimental and Therapeutic Medicine 12, no. 2 (2016): 1196-1200. https://doi.org/10.3892/etm.2016.3407
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